A previous Dutch guideline for prophylaxis of hematogenous PJI (HPJI) caused defensive medicine and incorrect own guidelines. There was a need for a better national guideline, developed cooperatively by orthopedic surgeons and dentist. A committee of Dutch Orthopedic and Dental Society, performed a systematic literature review to answer the question: We included 9 papers as follows: RCT's and systematic reviews: 539 abstracts > 33 full papers > 1 paper included. observational studies: 289 abstracts > 12 full papers > 5 papers. reference-to-reference: 3 papers. The nine papers’ quality was scored according the GRADE method. In addition we studied in non-included literature on further information about additional questions of pathophysiology, risk factors and risk procedures.Aim
Method
