In acetabular revision press-fit cups usually are used in smaller defects and contact to the host bone should be more than 50 %. Due to the thin wall thickness and the surface design the cementless press-fit cup Allofit S has a specific characteristic during implantation. Therefore this cup was used for revision with greater acetabular defects and analysed in a prospective study. The press-fit in these cases was 4 mm and additional 2 or 3 screws into the Os ilium were used. 64 cups were were followed prospectively for 38.3 months with a minimum of 24 months and examined clinically (Harris-Hip-Score) and radiographically for migration (Method of Nunn et al.) and loosening (Method of Delee and Charnley). Corresponding to Nunn et al. and Blum et al., cup migration was defined to be a change of position greater than 3 mm or referring to Cordero-Ampuero et al. and Dickob et al. a change of inclination greater than 5 degrees. There were 25 revisions of the cup and 39 complete exchanges of the prosthesis due to 54 aseptic and 10 septic loosenings (two-step revision with spacer and cementless reimplantation). There were acetabular defects of type Paprosky 2A in 12 cases, of type 2B in 15 cases, type 2C in 19 cases, type 3A in 16 cases and type 3 B in 2 cases. The average age of the patients was 70.9 ± 8.9 years. The Harris-Hip-Score increased from 45.4 ± 14.9 points preoperatively to 81.8 ± 17.5 points one year and 82.3 ± 17.1 points two years postoperative. There was no loosing or significant migration of the cups. The Allofit S press-fit cup shows good result in cup revisions with greater acetabular defects when using a press-fit of 4 mm and additional 2 or 3 screws. In these cases it seems to be a good and cheeper alternative to specific implants like trabecular metal cups.
We analysed the serum C-reactive protein level, synovial fluid obtained by joint aspiration and five synovial biopsies from 145 knee replacements prior to revision to assess the value of these parameters in diagnosing late peri-prosthetic infection. Five further synovial biopsies were used for histological analysis. Samples were also obtained during the revision and incubated and analysed in an identical manner for 14 days. A total of 40 total knee replacements were found to be infected (prevalence 27.6%). The aspiration technique had a sensitivity of 72.5% (95% confidence interval (CI) 58.7 to 86.3), a specificity of 95.2% (95% CI 91.2 to 99.2), a positive predictive value of 85.3% (95% CI 73.4 to 100), a negative predictive value of 90.1% (95% CI 84.5 to 95.7) and an accuracy of 89%. The biopsy technique had a sensitivity of 100%, a specificity of 98.1% (95% CI 95.5 to 100), a positive predictive value of 95.2% (95% CI 88.8 to 100), a negative predictive value of 100% and an accuracy of 98.6%. C-reactive protein with a cut-off-point of 13.5 mg/l had a sensitivity of 72.5% (95% CI 58.7 to 86.3), a specificity of 80.9% (95% CI 73.4 to 88.4), a positive predictive value of 59.2% (95% CI 45.4 to 73.0), a negative predictive value of 88.5% (95% 81.0 to 96.0 CI) and an accuracy of 78.1%. We found that biopsy was superior to joint aspiration and C-reactive protein in the diagnosis of late peri-prosthetic infection of total knee replacements.