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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XVIII | Pages 60 - 60
1 May 2012
McGonagle L Jones M Dowson D King P Theobald P
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Frictional resistance to tendon gliding is minimised by surrounding loose areolar tissues. During periods of prolonged immobilisation, for example post tendon-repair, adhesions can form between the two adjacent tissues, thereby limiting function. Whilst agents applied during surgery are recognised to succeed in adhesion prevention, they have also been reported to provide some reduction in friction during in vitro tendon-bony pulley investigations. This study investigated the effectiveness of common anti-adhesion agents in lubricating the tendon-surrounding tissue contact by comparison with a control study. By using a validated apparatus and with reference to the Stribeck curve, it was determined that the natural in vivo contact is likely to be lubricated by a film of synovial-like fluid. Application of all anti-adhesives generated a similarly efficient lubricating system, and hence administration of these agents should be encouraged to all regions of the tendon disrupted during surgery. Minimising frictional resistance to gliding will reduce the likelihood of tendon ‘gapping’ - and subsequently failure - at the repair site.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 59 - 59
1 Mar 2010
Landham* P Nokes L Byrne C Dowson D Dent C Theobald P
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Paratenonitis describes inflammation of the paratenon and commonly presents as an overuse injury. The paratenon is the connective tissue sheath that surrounds tendons - including tendo Achilles, and serves to minimise friction with the outer layer of the tendon, the epitenon. Whilst this conjunction allows the tendon to glide smoothly on muscular contraction, the presentation of paratenonitis typically follows periods of frequent, repetitive musculoskeletal movements; hence, paratenonitis commonly afflicts the elite and, albeit to a lesser extent, amateur athlete. The extent to which friction at the epitenon-paratenon juncture contributes to this tendinopathy remains unclear, and this study is therefore concerned with the coefficient of friction and the lubrication regime.

By using a specially designed and validated apparatus, the in vivo paratenon-epitenon conjunction was approximated using bovine flexor tendon paratenon and a glass disc; this is being an equivalent experimental set-up to that used in other studies exploring soft tissue contacts. Bovine synovial fluid was used to lubricate the conjunction at 37 deg C, and the frictional characteristics were analysed over a range of sliding speeds and loads.

The coefficient of friction was found to generally lie between 0.1 – 0.01. This range suggests that a system of mixed lubrication applies - where the synovial fluid is causing partial separation of the two surfaces. However, when the data is plotted in the form of a Stribeck curve, the trend suggests that boundary lubrication prevails - where lubrication is determined by surface-bound proteins.

The coefficient of friction at the epitenon-paratenon interface appears to be approximately one order of magnitude greater than that typically reported within the healthy synovial joint. Additionally, the synovial joint is thought to exhibit some fluid film lubrication (i.e. total surface separation), whereas the epitenon-paratenon lubrication regime appears to vary only between the inferior mixed and boundary systems - depending on the specific biomechanical conditions. This data would suggest that the coefficient of friction at the epitenon-paratenon interface is relatively high and thus is potentially significant in the incidence of paratenonitis. Such a hypothesis could be of particular interest to sports-medicine and orthopaedic specialists.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_III | Pages 416 - 416
1 Oct 2006
Isaac G Hardaker C Flett M Dowson D
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Purpose of study There is renewed scientific interest in the use of metal-metal bearings for hip replacements. Such bearings have lower volumetric wear rates compared to metal or ceramic on polyethylene bearings. They permit the use of large diameter bearings which potentially have the benefit of reduced dislocation. They also allow the use of thin components without the risk of fracture associated with similar ceramic-ceramic components. However, there remain concerns about the long-term effects of nanometre sized debris and the release of metal ions. It is therefore critical to understand which parameters are important in minimising the amount of debris generated. This study investigated the effect of design and materials on the wear rates in a hip simulator.

Methods Wear studies were carried out in a 10 station ProSim hip simulator in 25% newborn calf serum. A Paul type load curve was applied (maximum load 3000N, minimum 300N) in an anatomical configuration. The extent of a fluid film between the bearing surfaces was determind by measuring the voltage drop between the components. Test samples were made from low-carbon (< 0.05%) and high-carbon (> 0.20%) CoCrMo alloys in various conditions. These samples had bearing surface diameters of 16–54.5mm. The diametral clearance between the femoral head and acetabular cups were from 50–300um.

Results The results of this study were that the low-carbon material wears more than high-carbon materials, there is no significant difference in wear performance of the various forms of high-carbon material tested (wrought, cast, and cast and heat treated), and wear decreased with reduced clearances and increased component diameter. Voltage changes indicated that reduced clearances resulted in component separation and fluid film lubrication

Conclusions These results are consistent with the hypothesis that large diameter metal-on-metal bearings with optimized bearing surface geometry operate in the mixed and/or fluid film lubrication regime.


The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 2 | Pages 280 - 285
1 Mar 1996
Wroblewski BM Siney PD Dowson D Collins SN

We report the findings from independent prospective clinical and laboratory-based joint-simulator studies of the performance of ceramic femoral heads of 22.225 mm diameter in cross-linked polyethylene (XLP) acetabular cups. We found remarkable qualitative and quantitative agreement between the clinical and simulator results for the wear characteristics with time, and confirmed that ceramic femoral heads penetrate the XLP cups at only about half the rate of otherwise comparable metal heads.

In the clinical study, 19 hips in 17 patients were followed for an average of 77 months. In the hip-joint simulator a similar prosthesis was tested for 7.3 million cycles.

Both clinical and simulator results showed relatively high rates of penetration over the first 18 months or 1.5 million cycles, followed by a very much lower wear thereafter. Once an initial bedding-in of 0.2 mm to 0.4 mm had taken place the subsequent rates of penetration were very small. The initial clinical wear during bedding-in averaged 0.29 mm/year; subsequent progression was an order of magnitude lower at about 0.022 mm/year, lower than the 0.07 mm/year in metal-to-UHMWP Charnley LFAs.

Our results show the excellent tribological features of alumina-ceramic-to-XLP implants, and also confirm the value of well-designed joint simulators for the evaluation of total joint replacements.


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 1 | Pages 149 - 150
1 Jan 1990
Isaac G Wroblewski B Atkinson Dowson D


The Journal of Bone & Joint Surgery British Volume
Vol. 69-B, Issue 1 | Pages 61 - 63
1 Jan 1987
Wroblewski B Lynch M Atkinson Dowson D Isaac G

We examined 59 cemented high density polyethylene sockets removed at revision hip arthroplasty. Of these 19 showed areas of wear between the outside of the socket and the acetabular bone. This was associated with lack of acrylic cement in those areas and was also related to the depth of the wear on the articulating surface of the socket. It is suggested that, in some cases, changes at the bone-cement junction are secondary to socket loosening and abrasion against the bone of the acetabulum, rather than to particles migrating from the metal-polyethylene interface. It is therefore important that impingement of the neck of the femoral stem on the edge of the cup be avoided and that, when the socket is inserted, it is not in direct contact with the bone.


The Journal of Bone & Joint Surgery British Volume
Vol. 60-B, Issue 3 | Pages 375 - 382
1 Aug 1978
Dowling J Atkinson Dowson D Charnley J

In laboratory tests, the ultra-high molecular weight polyethylene used for the acetabular cups of Charnley hip prostheses has a very low wear rate against steel. In the body radiographic measurements indicate that the polyethylene wears more rapidly. In order to investigate this higher wear rate, the sockets of acetabular cups removed at post-mortem have been examined using optical and electron microscopy. It has been shown that a socket wears predominantly on its superior part and that this is a direct consequence of the orientation of the cup in the body and the direction of loading of the hip. In the worn region the femoral head in effect bores out a new socket for itself, a process which is visible with the naked eye after approximately eight years. Electron microscopy shows that the predominant wear mechanism is adhesion, but after about eight years the appearance of surface cracks suggests that surface fatigue is taking place in addition to this. Laboratory wear tests have shown that pure surface fatigue is not sufficient to account for the high clinical wear rate. Other deformation processes are suggested and discussed with regard to the higher clinical wear rate.