The volume of ambulatory total hip arthroplasty (THA) procedures is increasing due to the emphasis on value-based care. The purpose of the study is to identify the causes for failed same-day discharge (SDD) and perioperative factors leading to failed SDD. This retrospective cohort study followed pre-selected patients for SDD THA from 1 August 2018 to 31 December 2020. Inclusion criteria were patients undergoing unilateral THA with appropriate social support, age 18 to 75 years, and BMI < 37 kg/m2. Patients with opioid dependence, coronary artery disease, and valvular heart disease were excluded. Demographics, comorbidities, and perioperative data were collected from the electronic medical records. Possible risk factors for failed SDD were identified using multivariate logistic regression.Aims
Methods
Due to the opioid epidemic, our service developed a cultural change highlighted by decreasing discharge opioids after lower extremity arthroplasty. However, concern of potentially increasing refill requests exists. As such, the goal of this study was to analyze whether decreased discharge opioids led to increased postoperative opioid refills. We retrospectively reviewed 19,428 patients undergoing a primary hip or knee arthroplasty at a single institution from 2016–2019. Patients that underwent secondary procedures within that timeframe were excluded. Two-thousand two-hundred and forty-one patients (12%) were on narcotics preoperatively or had chronic pain syndrome. Two reductions in routine discharge narcotics were performed over this timeframe. First, 8,898 patients routinely received 750 morphine milligram equivalents (MMEs). After the first reduction, 4,842 patients routinely received 520 MMEs. After a second reduction, 5,688 patients routinely received 320 MMEs. We analyzed refill rates, refill MMEs, and whether discharge MMEs were associated with refill MMEs in a multivariate model.Introduction
Methods
In the United States, cementless femoral fixation remains the dominant mode of fixation for femoral neck fractures, despite strong worldwide registry data that supports cemented fixation. The reason for this discrepancy remains unknown, controversial and often difficult to compare due to multiple variables. The purpose of this study was to evaluate a matched cohort of patients undergoing arthroplasty for femoral neck fractures and assess outcomes of revisions, periprosthetic fractures and mortality. This is an exact matched cohort study. Cemented fixation cases were exact matched to cementless fixation cases in a 1:1 fashion based on age, sex and Charlson Comorbidity Index (CCI). Outcome variables included: revision for periprosthetic fracture; all cause revision and mortality at any time point; all cause revision and mortality within 1-year and within 90-days. The primary independent variable was femoral fixation (cemented, cementless) and covariates included race (black, white, other), ethnicity (hispanic, non-hispanic), teaching status (minor, major, nonteaching) and bedsize (1–99, 100–399, >=400). Chi-square tests and multivariable logistic regression models were used for statistical analysis.Introduction
Methods
Over the past few decades, opioid abuse has become a major threat to public health. In 2013 alone, enough opioid prescriptions were written in the United States for every American adult to have their own bottle of pills. Since then, opioid prescribing rates and opioid related deaths have continued to grow, with over 46 people dying on average each day from prescription opioid overdoses in 2016. Orthopaedic surgeons are among the top 5 specialties in the number of opioid prescriptions written. For many common surgeries, such as total knee arthroplasty (TKA), post-discharge prescriptions are based on prescriber habits and opinion. There exists limited data-driven protocols to guide post-operative opioid prescribing practices. The purpose of this prospective study was to determine the average postoperative opioid consumption in patients undergoing primary TKA using a novel mobile text messaging platform. We hypothesized that majority of patients undergoing TKA do not properly dispose of left over pills after surgery. 95 patients undergoing primary unilateral TKA with one of nine arthroplasty surgeons at a single orthopaedic specialty hospital were prospectively enrolled. Daily pain levels and opioid consumption, and quantity and disposal patterns for left over medications were collected for six weeks following surgery using a novel mobile phone text messaging system. This system automatically queried patients twice a day, storing responses on a secure third-party host that investigators monitored and used to generate data reports in real-time.Introduction
Methods
Tranexamic acid (TXA) and fibrin sealants have gained widespread use in total knee arthroplasty. They can decrease bleeding, drainage volume, hematoma formation, and incidence of blood transfusion. However, they are costly and carry a theoretical risk of infection transmission and thrombosis. This study compares the two pharmacologic interventions to preoperative autologous blood donation as well as no intervention. This prospective study evaluated a process change within our blood management program over the last five years. The program began initially with a comparison of only routine hemostasis compared to routine preoperative autologous blood donation (PABD) for all patients (Group 1), which then evolved into a targeted PABD protocol where only anaemic patients predonated (Group 2). Subsequently, patients received topical fibrin sealant for a year (Group 3), after which the topical TXA protocol was introduced and is still in place (Group 4).Background
Methods
This review summarises the technique of impaction
grafting with mesh augmentation for the treatment of uncontained
acetabular defects in revision hip arthroplasty. The ideal acetabular revision should restore bone stock, use
a small socket in the near-anatomic position, and provide durable
fixation. Impaction bone grafting, which has been in use for over
40 years, offers the ability to achieve these goals in uncontained
defects. The precepts of modern, revision impaction grafting are
that the segmental or cavitary defects must be supported with a
mesh; the contained cavity is filled with vigorously impacted morselised
fresh-frozen allograft; and finally, acrylic cement is used to stabilise
the graft and provide rigid, long-lasting fixation of the revised
acetabular component. Favourable results have been published with this technique. While
having its limitations, it is a viable option to address large acetabular
defects in revision arthroplasty. Cite this article:
In the 1960s Sir John Charnley introduced to clinical practice his low friction arthroplasty with a highly polished cemented femoral stem. The satisfactory long term results of this and other cemented stems support the use of cement for fixation. The constituents of acrylic cement remained virtually unchanged since the 1960s. However, in the last three decades, advances in the understanding of cement fixation, mixing techniques, application, pressurization, stem materials and design provided further improvements in the clinical results. The technical changes in cementing technique that proved to be beneficial include femoral preparation to diminish interface bleeding, careful lavage, reduced cement porosity by vacuum mixing, a cement restrictor, pre-heating of the stem and polymer, retrograde canal filling and pressurization with a cement gun, stem centralization and stem geometries that increase the intramedullary pressure and intrusion into the bone of the cement. Some other changes proved to be detrimental and were abandoned, such as the use of Boneloc cement that polymerised at a low temperature, and roughening and pre-coating of stem surface. In recent years there has been a tendency towards an increased use of cementless femoral fixation for primary hip arthroplasty. The shift in the type of fixation followed the consistent, durable fixation obtained with uncemented acetabular cups, ease of implantation and the poor results of cemented femoral fixation of rough and precoated stems. Unlike cementless femoral fixation, modern cemented femoral fixation has numerous advantages: it's versatile, durable and can be used regardless of the diagnosis, proximal femoral geometry, natural neck version, and bone quality. It can be used in combination with antibiotics in patients with a history or predisposition for infection. Intraoperative femoral fractures and postoperative thigh pain are extremely rare. Survivorship has not been surpassed by uncemented femoral fixation and it continues to be my preferred form of fixation. However, heavy, young male patients may exhibit a slightly higher aseptic loosening rate.
Uncontained acetabular defects with loss of superior iliac and posterior column support (Paprosky 3B) represent a reconstructive challenge as the deficient bone will preclude the use of a conventional hemispherical cup. Such defects can be addressed with large metallic constructs like cages with and without allograft, custom tri-flange cups, and more recently with trabecular metal augments. An underutilised alternative is impaction bone grafting, after creating a contained cavitary defect with a reinforcement mesh. This reconstructive option delivers a large volume of bone while using a small-size socket fixed with acrylic cement. Between 2006 and 2014, sixteen patients with a Paprosky 3B acetabular defect were treated with cancellous, fresh frozen impaction grafting supported by a peripheral reinforcement mesh secured to the pelvis with screws. A cemented all polyethylene cup was used. Preoperative diagnosis was aseptic loosening (10 cemented and 6 non-cemented). The femoral component was revised in 9 patients. Postoperative course consisted of 3 months of protected weight bearing. Patients were followed clinically and radiographically. One patient had an incomplete postoperative sciatic palsy. After a mean follow up of 40 months (24 to 104) none of the patients required re-revision. One asymptomatic patient presented with aseptic loosening 9 years postoperatively. Hardware failure was not observed. All patients had radiographic signs of graft incorporation and bone remodeling. There were no dislocations. The early and mid-term results of revisions for large acetabular defects with this technique are encouraging. Reconstitution of hip center of rotation and bone stock with the use of a small-size implant make this technique an attractive option for these large defects. Longer follow-up is needed to assess survivability.
Stiffness after total knee arthroplasty is a common occurrence. Despite its prevalence, little is known as to which patients are at risk for poor range of motion after total knee arthroplasty. The purpose of this study was to determine the risk factors for manipulation under anesthesia (MUA) after total knee arthroplasty (TKA). Using a single institution registry, 160 patients who underwent a manipulation under anesthesia after total knee arthroplasty between 2007 and 2013 were retrospectively evaluated. Each patient was 1:1 matched by age, gender and laterality to a control group of 160 patients who did not require MUA after TKA. Risk factors for MUA were assessed, and included medical co-morbidities, BMI, prior operations, and preoperative range of motion.Introduction
Methods
Wasted implants represent both an increased risk and cost to our healthcare system. In our institution, a sterilely packaged implant that is opened and not implanted is wasted in one out of 20 primary total knee replacement procedures. The cost of these wasted implants exceeds $1 million per year. We propose the introduction of a novel, computer based, e.Label and compatibility system to reduce implant-related medical errors and waste in total knee arthroplasty. We hypothesize that the implementation of this system will help reduce medical errors and wasted implants by improving and standardizing the visual markers and by ensuring that parts are compatible so that implant mismatches and inappropriate laterality are prevented. A software program was implemented which creates an e.Label for all components (Figure 1) and checks imbedded, manufacturer provided, compatibility charts to ensure that parts are of appropriate laterality, and are compatible with each other. Upon implementation, the program was studied prospectively for seven months and compared to a retrospective cohort in regards to number, type, and cost of wasted implants. Critical errors that were detected were also recorded.INTRODUCTION
METHODS
It is debatable whether high flexion total knee arthroplasty (TKA) designs will improve postoperative flexion, function or will diminish the need for manipulation under anesthesia (MUA). We retrospectively analyzed range of motion (ROM), flexion, Knee Society Score (KSS), and rate of MUA in a consecutive group of patients who underwent TKA with a conventional PS or a high flexion (HF) insert using identical surgical technique, implant design and postoperative care. Fifty TKAs with a standard posterior stabilized insert (PS) were matched with 50 who received a high flexion insert (HF) for patient’s age, gender, preoperative ROM, and KSS. The patient’s ROM and KSS were obtained at 6 weeks, 4 months, and 1 year postoperatively. The outcome variables (flexion, ROM, KSS and manipulation rate) in the two groups were compared using the generalized estimating equations method. A second analysis of patients with preoperative flexion equal or greater than 120 degrees was performed. The ROM, flexion, and patient reported KSS was similar in the PS and HF groups at each one of the time periods. The rate of MUA was also similar. Patients with a preoperative ROM of at least 120° showed similar results. Our study found that 1 year after surgery, patients who underwent TKA with a PS or a HF insert achieved similar flexion, ROM and function.
The role of surface finish on the survivorship of cemented stems is controversial. The purpose of this study is to prospectively evaluate the mid-term clinical and radiographic performance of a cohort of patients who underwent total hip replacement with two identical cemented femoral stems differing only in surface finish (VerSys, Zimmer, Warsaw, IN). 64 total hip replacements with a rough stem and 138 total hip replacements with a satin finish stem were followed clinically and radiographically for 4 to 7 years. All surgeries were performed by one surgeon. The groups had similar demographics, diagnosis, length of follow up, cement mantle quality and alignment. The preoperative and postoperative Hospital for Special Surgery Hip Score at last follow up was not significantly different among the two groups. Five hips in the rough group and none in the satin group developed aseptic loosening (p=0.0009). The femoral bone-cement interface revealed progressive radiolucent lines or osteolysis in 8 out of 64 rough stems and in 3 out of 138 satin stems (p=0.01). There were progressive radiolucencies or osteolysis in 44 out of possible 448 Gruen zones in the rough surface group and in 8 out of possible 966 Gruen zones in the satin finish group (p<
0.001). A rough, textured stem is more likely to fail at intermediate follow-up than a satin surface stem. We recommend that the surface of cemented stems should be satin or polished, with a Ra of less than 20 microinches.
Backside wear is generated at the non-articulating surfaces of modular acetabular cups. We compared the backside wear of retrieved liners from cementless non-modular and modular cups of first and second generation designs. We match paired for time in situ, patient age and weight, 9 retrieved Harris Galante type 1 liners, 9 Harris Galante type 2, 9 Trilogy, and 9 liners from a modern two-piece preassembled cup (Implex). The average time in situ was 2.5 years (1 to 7). The backside was divided in quadrants and each one examined under a 10x binocular loupe and rated with a score from 0 (absence of wear) to 3 (severe backside wear) for a total ranging from 0 to 12. Among 36 quadrants in the HG1 group there were 3 rated 1, 23 rated 2, and 10 rated 3. In the HG2 group, there was 1 quadrant rated 0, 16 rated 1, 14 rated 2, and 5 rated 3. In the Trilogy group, there were 6 quadrants rated 0, 27 rated 1, and 3 rated 2. In the Implex group, there were 15 quadrants rated 0, 21 rated 1. The average total backside wear score was 8.4; 7.3; 3.7; and 2.3 respectively. The HG cups demonstrated more severe backside wear than the Trilogy and Implex (HG1 vs Trilogy and HG1 vs Implex: p<
0.001; HG2 vs Trilogy and HG2 vs Implex: p<
0.02). There was a tendency towards less backside wear in the Implex cup when compared to the Trilogy (p=0.04). The difference between the HG1 and HG2 was not significant. Despite the limitations imposed by the small sample studied, the presence of multiple screw holes in the Harris-Galante retrievals, and sub-optimal matching for sex, height, and varied indication for revision, we detected significant reduction in the backside wear of modern modular and non-modular acetabular cups when compared to first generation modular designs.
Particles generated at the non articulating surface (backside) of modular acetabular components have been implicated in the development of periprosthetic osteolysis after THA. Several design changes have been introduced in modern acetabular cups in an attempt to reduce backside wear, including the use of “non-modular cups”. We compared the backside wear of retrieved cementless non-modular cups, with modular cups of first and second generation designs. Nine retrieved non-modular cups (Implex) were match-paired for time-in-situ, patient age and weight, with 9 retrieved Trilogy cups, 9 Harris-Galante 1, and 9 Harris-Galante 2. The average time in situ was 2.5 years (1–7). The backside was divided in quadrants and each rated with a value from 0 (absence of wear) to 3 (severe backside wear) for a total ranging from 0 to 12. This new score was validated for intra and inter observer reproducibility. Among 36 quadrants in the HG1 group there were 3 rated 1, 23 rated 2, and 10 rated 3. In the HG2 group, 1 quadrant was rated 0, 16 rated 1, 14 rated 2, and 5 rated 3. In the Trilogy group, 6 quadrants were rated 0, 27 rated 1, and 3 rated 2. In the Implex group, 15 quadrants were rated 0, 21 rated 1. The average backside wear score and 95%CI were 8.4 (7.6–9.3); 7.3 (5.5–9.1); 3.7 (3.2–4.1); and 2.3 (1.3–3.4) respectively. The HG cups demonstrated more severe backside wear than the Trilogy and Implex (p<
0.02). There was a tendency towards less backside wear in the Implex cup when compared to the Trilogy (p=0.04). The difference between the HG1 and HG2 was not significant. We detected significant reduction in the backside wear of modern modular and non-modular acetabular cups when compared to first generation modular designs.
The role of surface finish on the survivorship of cemented stems is controversial. The purpose of this study is to prospectively evaluate the mid-term clinical and radiographic performance of a cohort of patients who underwent total hip replacement with two identical cemented femoral stems differing only in surface finish (VerSys, Zimmer, Warsaw, IN). 64 total hip replacements with a rough stem (Ra: 70–100 microinches) and 138 total hip replacements with a satin finish stem (Ra: 20–25 microinches) were followed clinically and radiographically for 4 to 7 years. All surgeries were performed by one surgeon during a period of 1 year, utilizing the same surgical technique, acetabular cup, cement type and cementing technique. The groups had similar demographics, diagnosis, preoperative clinical score, cement mantle quality, alignment, and length of follow up. The preoperative and postoperative Hospital for Special Surgery Hip Score at last follow up of the patients with a successful operation was not significantly different among the two groups. Five hips in the rough group and none in the satin group developed aseptic loosening (p=0.0009). The femoral bone-cement interface revealed progressive radiolucent lines or osteolysis in 8 out of 64 rough stems and in 3 out of 138 satin stems (p=0.01). There were progressive radiolucencies or oste-olysis in 44 out of possible 448 Gruen zones in the rough surface group and in 8 out of possible 966 Gruen zones in the satin finish group (p<
0.001). A rough, textured stem is more likely to fail at intermediate follow-up than a satin surface stem. We recommend that the surface of cemented stems should be satin or polished, with a Ra of less than 20 microinches.
We evaluated the safety and efficacy of a multimodal approach for prophylaxis of thromboembolism after THA, which includes preoperative autologous blood donation; hypotensive epidural anesthesia; intravenous administration of heparin during surgery, before femoral preparation when the thrombogenesis is maximally activated; expeditious surgery, minimizing femoral vein occlusion and blood loss; pneumatic compression; and early mobilization after surgery. 1946 consecutive, non-selected patients (2016 THAs) who received multimodal thromboembolic prophylaxis were followed prospectively for 3 months. Only patients with history of thrombocytopenia (platelet count <
100.000) or adverse reaction to heparin were excluded. The average age was 65 years (14 to 93), ASA classification was 1 in 14%, 2 in 48%, 3 in 37% and 4 in 1% of patients. There was a history of DVT in 86 patients and PE in 35. After surgery, the patients also received pharmacologic prophylaxis for 6 weeks (aspirin 83%; warfarin 17%). The incidence of asymptomatic DVT assessed by ultrasound in the first 198 consecutive patients was 7.1% (14 of 198). The incidence of clinical DVT in the subsequent 1748 patients was 1.8% (32 of 1748). Symptomatic PE occurred in 0.56% (11 of 1946), none of them fatal. The rate of PE in patients receiving aspirin was 0.49% (8 of 1615) and warfarin 0.9% (3 of 331). There was 1 PE among 95 patients with a prior history of PE or DVT (1%). One morbidly obese patient died of a cardiac arrhythmia confirmed by autopsy. There was only one major bleeding complication: one patient with a history of coagulopathy developed hematuria requiring a bladder flush and five units of blood, with an uneventful recovery. No patients developed epidural hematoma following administration of intraoperative heparin. A multimodal approach to prevent thromboembolic disease, showed results that compare favorably with the literature, and with our historic control of 2592 THRs without intraoperative heparin (PE rate of 1%; 0.04% fatal). This multimodal approach appears safe and efficacious as thromboembolic prophylaxis. Our low rate of PE does not support routine anticoagulation prophylaxis with drugs with a significant risk of bleeding.