Advertisement for orthosearch.org.uk
Results 1 - 9 of 9
Results per page:
The Bone & Joint Journal
Vol. 101-B, Issue 1_Supple_A | Pages 41 - 45
1 Jan 2019
Jones CW De Martino I D’Apolito R Nocon AA Sculco PK Sculco TP

Aims

Instability continues to be a troublesome complication after total hip arthroplasty (THA). Patient-related risk factors associated with a higher dislocation risk include the preoperative diagnosis, an age of 75 years or older, high body mass index (BMI), a history of alcohol abuse, and neurodegenerative diseases. The goal of this study was to assess the dislocation rate, radiographic outcomes, and complications of patients stratified as high-risk for dislocation who received a dual mobility (DM) bearing in a primary THA at a minimum follow-up of two years.

Materials and Methods

We performed a retrospective review of a consecutive series of DM THA performed between 2010 and 2014 at our institution (Hospital for Special Surgery, New York, New York) by a single, high-volume orthopaedic surgeon employing a single prosthesis design (Anatomic Dual Mobility (ADM) Stryker, Mahwah, New Jersey). Patient medical records and radiographs were reviewed to confirm the type of implant used, to identify any preoperative risk factors for dislocation, and any complications. Radiographic analysis was performed to assess for signs of osteolysis or remodelling of the acetabulum.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 44 - 44
1 Jan 2018
Sculco T De Martino I Sculco P D'Apolito R Nocon A
Full Access

Instability continues to be a troublesome complication after THA and has been reported to be the main indication for revision in the United States, accounting for 22.5% of revisions. Risk factors associated with dislocation include: age of 75 years or older, body mass index (BMI) of 30 kg/m2 or greater, alcohol abuse, and neuro-degenerative diseases such as multiple sclerosis or Parkinson's disease. Dual-mobility articulations have become an increasingly popular option for these “at risk” primary THAs. Few studies have assessed their use in this complex patient population. The purpose of this study was to assess dislocation rate, radiographic outcomes and complications of the dual-mobility articulation in the setting of primary THA for patients at high risk for dislocation at a minimum follow up of 2 years.

We retrospectively reviewed 151 dual mobility acetabular components, that had been performed using a single design (ADM Stryker, Mahwah, NJ) between 2010 and 2014 at a single institution by a single surgeon. The mean age at time of index surgery was 82 years (range, 73–95), 114 patients were female, and mean BMI was 26.2 kg/m2 (range, 16.1–60.9). Dislocation rate and complications associated with dual mobility cups were reviewed, along with the radiographic outcomes after an average follow-up period of 3.6 years (range, 1.9–6.1 years).

The indication for hip replacement was osteoarthritis in all cases. We had one traumatic dislocation which required component revision after intraprosthetic dislocation following an attempt of closed reduction. There were no further dislocations in this cohort. No progressive radiolucencies or component positional changes were seen on radiographic assessment.

At short-term follow-up dual mobility provides a stable reconstruction in patients at high risk of dislocation with excellent radiographic results. Longer follow-up is needed to confirm the durability of these reconstructions.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 12 - 12
1 Jan 2018
De Martino I D'Apolito R Nocon A Sculco P Sculco TP Bostrom M
Full Access

Proximal femoral replacements are commonly used in oncologic limb salvage procedures. Recently, these megaprostheses have been utilized in complex revision arthroplasties where proximal femoral bone is compromised. The purpose of this study is to evaluate the clinical and radiographic survivorship of proximal femoral replacements as a salvage treatment for bone loss after hip arthroplasty. We retrospectively reviewed the clinical and radiographic outcomes of 31 proximal femoral replacements of a single design between 2004 and 2013 at a single institution. The mean age at time of index surgery was 62 years, 58% were female, and mean BMI was 28.1 Kg/m2. The indications and complications associated with megaprosthesis implantation were collected. Average follow-up was 60 months (range 24–120 months). Kaplan-Meier survivorship assessed clinical and radiographic survivorship. Indication for revision, use of a constrained liner and construct length were assessed as risk factors for construct failure.

The indications for proximal femoral replacement were periprosthetic infection (n=12, 38.7%), aseptic loosening (n=10, 32.3%), periprosthetic fracture (n=6, 19.3%), and non-union (n=3, 9.7%). A constrained liner was used in 22 hips (71%). The average length of bone resection was 148 cm (range 81–240 cm). There were nine revisions (29.2%): 3 for infection (9.7%) 2 for dislocation (6.5%), 2 for aseptic loosening (6.5%), and 2 for periprosthetic fracture (6.5%). Two of the 3 infections were in patients treated for infection. Overall survivorship was at 70.8%. There was no relation between the length of the bone resection, indication for revision and failure rate.

Proximal femoral replacement in non-oncologic revision hip arthroplasty demonstrated a high failure rate at 2–10 year follow-up. Despite the high failure rate, the benefits of this salvage construct are that they allow full weight-bearing and allow rapid mobilization with minimal morbidity.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 93 - 93
1 Feb 2017
De Martino I Sculco P Meyers K Nocon A Wright T Sculco T
Full Access

Introduction

Successful cementless acetabular designs require sufficient initial stability between implant and bone (with interfacial motions <150 μm) and close opposition between the porous coating and the reamed bony surface of the acetabulum to obtaining bone ingrowth and secondary stability. While prior generations of cementless components showed good clinical results for long term fixation, modern designs continue to trend toward increased porosity and improved frictional characteristics to further enhance cup stability.

Objectives

We intend to experimentally assess the differences in initial stability between a hemispherical acetabular component with a highly porous trabecular tantalum fixation surface (Continuum® Acetabular System, Zimmer Inc, Warsaw, IN)(Fig 1) and a hemispherical component with the new highly porous Trabecular Titanium® surface (Delta TT, Lima Corporate, Italy)(Fig 2) manufactured by electron beam melting.


The Bone & Joint Journal
Vol. 99-B, Issue 1_Supple_A | Pages 18 - 24
1 Jan 2017
De Martino I D’Apolito R Soranoglou VG Poultsides LA Sculco PK Sculco TP

Aims

The aim of this systematic review was to report the rate of dislocation following the use of dual mobility (DM) acetabular components in primary and revision total hip arthroplasty (THA).

Materials and Methods

A systematic review of the literature according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines was performed. A comprehensive search of Pubmed/Medline, Cochrane Library and Embase (Scopus) was conducted for English articles between January 1974 and March 2016 using various combinations of the keywords “dual mobility”, “dual-mobility”, “tripolar”, “double-mobility”, “double mobility”, “hip”, “cup”, “socket”. The following data were extracted by two investigators independently: demographics, whether the operation was a primary or revision THA, length of follow-up, the design of the components, diameter of the femoral head, and type of fixation of the acetabular component.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 149 - 149
1 May 2016
De Martino I Sculco P Galasso O Gasparini G
Full Access

Introduction

The optimal management of severe tibial and/or femoral bone loss in a revision total knee arthroplasty (TKA) has not been established. Reconstructive methods include structural or bulk allografts, impaction bone-grafting with or without mesh augmentation, custum prosthetic components, modular metal augmentations of prosthesis and tumor prosthesis. Recently metaphyseal fixation using porous tantalum cones (Zimmer, Warsaw, IN) has been proposed as alternative strategy for severe bone loss.

Objectives

The purposes of this study were to determine the clinical and radiographic outcomes in patients who underwent revision knee arthroplasty with tantalum cones with a minimum of 5-year follow-up.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 111 - 111
1 Jan 2016
De Martino I D'Apolito R De Santis V Gasparini G
Full Access

Background

Tapered cementless femoral components have been used in total hip arthroplasty (THA) constructs for more than 20 years. The Synergy femoral component was introduced in 1996 as a second generation titanium proximally porous-coated tapered stem with dual offsets to better restore femoral offset at THA (Figure 1). The purpose of this study was to evaluate the outcome of the authors' experience using the Synergy stem at minimum 15 years of follow-up.

Material and methods

We retrospectively reviewed a consecutive series of 102 patients (112 hips) who underwent surgery between November 1996 and October 1998 for primary THA using cementless Synergy stem with a minimum 15-years follow-up. The mean age at the time of surgery was 61 years, and the mean duration of follow-up was 16.3 years. Seventeen patients were lost at FU (8 died before the 15 years mark, 8 changed residency, 1 not willing to be seen) with no problems related to the replaced hip. Ninety-four hips in 85 patients were available for clinical and radiologic analysis. Clinical results of the 94 THAs with more than 15 years of follow-up were assessed preoperatively and postoperatively at 5, 10 and 15 years by means of standard evaluation tools: SF12, WOMAC and Harris Hip Score. Thigh pain frequency and intensity were also recorded. Radiographic analysis (Figure 2) was focused on stem alignment, bone ingrowth, radiolucent lines presence, width and progression, stress-shielding and heterotopic ossification (HTO). Student paired test and Kaplan-Meier survival analysis were used for statistical analysis.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 161 - 161
1 Mar 2013
De Martino I De Santis V Fabbriciani C Gasparini G
Full Access

Pure tantalum has been proposed in orthopaedic surgery. Its chemical and physical properties have been widely studied in the past. From pure tantalum is obtained a spongy structure (Trabecular Metal Technology: TMT) that shows a full thickness porosity which is 2–3 times higher compared to other surfaces available for bone ingrowth with a three-dimensional porous arrangement in rough trabeculae. Pores (average diameter of 650 mm) are fully interconnected and represent 75–80% of the whole volume. TMT acetabular components have an elliptical shape and have an irregular external surface which both allow an optimal mechanical fit.

We retrospectively reviewed 212 cases of monoblock porous tantalum acetabular cup (Hedrocel, Stratec) implanted between 1999 and 2003 in a single centre with a minimum follow-up of 9–10 years; There were 98 men and 114 women, with an average age of 65 years. They all underwent primary or revision total hip arthroplasty or to acetabular component revision alone. In all patients a monoblock porous tantalum acetabular component with polyethylene directly compression molded into cup, with or without peripheral holes for screws, was implanted. In all primary procedures the same femoral stem (Synergy, Smith and Nephew) was implanted.

All patients were evaluated with a clinical examination (Harris Hip Score: HHS) and with standard radiographs of the pelvis preoperatively and 1, 3, 6 months and yearly postoperatively. The stability of the acetabular cup was determined by modified Engh's criteria.

The HHS score improved from 42 preoperatively to 94 after one year; at 13 years follow-up it was 95. The subjective outcome was widely satisfying, with the majority of patients experimenting good functional recovery and return to daily activities. Osteointegration of the acetabular component was present in all X-rays controls at one year after surgery. All post-operative evidence of residual bone loss (geodes, bone defects in revisions and in displasia) were no more radiographically evident after 1 year postoperatively as the host bone quickly filled these gaps. We did not observe osteolysis nor progressive radiolucent lines at the latest follow-up. None of the cups was revised, except 3 cases, revised for infection.

Both clinical and radiographic results are the same or even superior to those of coated implants. Our experience confirms that trabecular metal tantalum cups can avoid the formation of bone-implant interface membrane and consequently can avoid implant loosening. The most important advantages of TMT monoblock cups are: no potential for polyethylene backside wear, prevention of loosening and osteolysis, increased early fixation via friction, improved late biological stability, maximum bone-implant contact. High biocompatibility of porous tantalum and its elastic modulus very close to bone influence positively earlier and wider osteointegration of the implant. Larger series are needed to confirm the positive our preliminary results.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 207 - 207
1 May 2011
Pola E Proietti L Nasto L Colangelo D De Martino I Logroscino C
Full Access

Introduction: Osteoporosis is a disease characterized by a low bone mass and the development of nontraumatic fractures. Approximately 700,000 elderly women in the US are newly diagnosed with osteoporotic vertebral fractures every year. Noninvasive measurements of bone mineral density (BMD) are central to the diagnosis and management of osteoporosis. However, BMD alone is not completely satisfactory in vertebral fracture risk assessment. The aim of this study was to identify clinical and laboratoristic factors associated with an increased risk of vertebral fractures in osteoporotic Caucasian women and to define a new clinically relevant scale of risk.

Methods: 475 patients consecutively admitted at our ambulatory for the treatment of vertebral osteoporosis were included in the study. All patients were affected by post-menopausal osteoporosis according to the WHO classification criteria. Exclusion criteria were major infectious diseases, tumors and major diseases of sense organs. We attempted to determine whether parameters such as age, body mass index, smoking and alcohol habitudes, femoral and lumbar T-scores, femoral and lumbar Z-scores, femoral and lumbar BMD, total and bone alkaline phosphatase and L3 and T7 vertebral volumes were associated with the risk of vertebral fractures.

Results: 173 patients of the entire population presented at least one vertebral fracture for a total of 488 fractures (238 thoracic and 250 lumbar collapses). When considered alone, age (> 65 years-p=0,0001), lumbar T-score (≤-3,5-p=0,0001), lumbar Z-score (≤-2,5-p=0,0050), lumbar BMD (≤0,800-p=0,0017), femoral T-score (≤-3,5-p=0,0090), femoral Z-score (≤-2,5-p=0,0127), L3 volume (≤-2,0SD–p=0,0023) and T7 volume (≤-2,0SD–p=0,0075) were significantly associated with an increased risk of vertebral fractures. Considering only the patients with two fractures or more, the same parameters with the exception of the femoral T-score resulted strongly associated with the risk of new vertebral fractures. Moreover, there was a significantly increased risk of vertebral fractures when two or more of these parameters were present together (p = 0.02). On the base of the obtained data we have then defined a new scale of risk (from grade I-low risk to grade IV-very high risk-p=0.0123) confirmed in a prospective study conducted on 71 osteoporotic patients followed for 30 months.

Conclusion: We propose a new clinical scale to easily identify the osteoporotic patient at risk of new vertebral fractures.