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The Bone & Joint Journal
Vol. 105-B, Issue 6 | Pages 649 - 656
1 Jun 2023
Dagneaux L Amundson AW Larson DR Pagnano MW Berry DJ Abdel MP

Aims

Nonagenarians (aged 90 to 99 years) have experienced the fastest percent decile population growth in the USA recently, with a consequent increase in the prevalence of nonagenarians living with joint arthroplasties. As such, the number of revision total hip arthroplasties (THAs) and total knee arthroplasties (TKAs) in nonagenarians is expected to increase. We aimed to determine the mortality rate, implant survivorship, and complications of nonagenarians undergoing aseptic revision THAs and revision TKAs.

Methods

Our institutional total joint registry was used to identify 96 nonagenarians who underwent 97 aseptic revisions (78 hips and 19 knees) between 1997 and 2018. The most common indications were aseptic loosening and periprosthetic fracture for both revision THAs and revision TKAs. Mean age at revision was 92 years (90 to 98), mean BMI was 27 kg/m2 (16 to 47), and 67% (n = 65) were female. Mean time between primary and revision was 18 years (SD 9). Kaplan-Meier survival was used for patient mortality, and compared to age- and sex-matched control populations. Reoperation risk was assessed using cumulative incidence with death as a competing risk. Mean follow-up was five years.


Bone & Joint Research
Vol. 12, Issue 1 | Pages 58 - 71
17 Jan 2023
Dagneaux L Limberg AK Owen AR Bettencourt JW Dudakovic A Bayram B Gades NM Sanchez-Sotelo J Berry DJ van Wijnen A Morrey ME Abdel MP

Aims

As has been shown in larger animal models, knee immobilization can lead to arthrofibrotic phenotypes. Our study included 168 C57BL/6J female mice, with 24 serving as controls, and 144 undergoing a knee procedure to induce a contracture without osteoarthritis (OA).

Methods

Experimental knees were immobilized for either four weeks (72 mice) or eight weeks (72 mice), followed by a remobilization period of zero weeks (24 mice), two weeks (24 mice), or four weeks (24 mice) after suture removal. Half of the experimental knees also received an intra-articular injury. Biomechanical data were collected to measure passive extension angle (PEA). Histological data measuring area and thickness of posterior and anterior knee capsules were collected from knee sections.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 16 - 16
1 Feb 2020
Dagneaux L Karl G Michel E Canovas F Rivière C
Full Access

Introduction

The constitutional knee anatomy in the coronal plane includes the distal femoral joint line obliquity (DFJLO) which in most patients is in slight valgus positioning. Despite this native anatomy, the mechanical positioning of the femoral component during primary total knee arthroplasty (TKA) often ignores the native DFJLO opting to place the femur in a set degree of valgus that varies upon the practitioner's practice and experience. Unfortunately, this technique is likely to generate high rate of distal lateral femoral overstuffing. This anatomical mismatch might be a cause of anterior knee pain and therefore partly explain the adverse functional outcomes of mechanically aligned (MA) TKA. Our study aims at assessing the relationship between constitutional knee anatomy and clinical outcomes of MA TKA. We hypothesized that a negative relationship would be found between the constitutional frontal knee deformity, the distal femoral joint line obliquity, and functional outcomes of MA TKA with a special emphasize on patellofemoral (PF) specific outcomes.

Methods

One hundred and thirteen patients underwent MA TKA (posterior-stabilized design) for primary end-stage knee osteoarthritis. They were prospectively followed for one year using the New KSS 2011 and HSS Patella score. Residual anterior knee pain was also assessed. Knee phenotypes using anatomical parameters (such as HKA, HKS, DFJLO and LDFA (Lateral distal femoral angle)) were measured from preoperative and postoperative lower-limb EOS® images (Biospace, Paris, France). We assessed the relationship between the knee anatomical parameters and the functional outcome scores at 1 year postoperatively.