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The Bone & Joint Journal
Vol. 101-B, Issue 6_Supple_B | Pages 68 - 76
1 Jun 2019
Jones CW Choi DS Sun P Chiu Y Lipman JD Lyman S Bostrom MPG Sculco PK

Aims

Custom flange acetabular components (CFACs) are a patient-specific option for addressing large acetabular defects at revision total hip arthroplasty (THA), but patient and implant characteristics that affect survivorship remain unknown. This study aimed to identify patient and design factors related to survivorship.

Patients and Methods

A retrospective review of 91 patients who underwent revision THA using 96 CFACs was undertaken, comparing features between radiologically failed and successful cases. Patient characteristics (demographic, clinical, and radiological) and implant features (design characteristics and intraoperative features) were collected. There were 74 women and 22 men; their mean age was 62 years (31 to 85). The mean follow-up was 24.9 months (sd 27.6; 0 to 116). Two sets of statistical analyses were performed: 1) univariate analyses (Pearson’s chi-squared and independent-samples Student’s t-tests) for each feature; and 2) bivariable logistic regressions using features identified from a random forest analysis.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_13 | Pages 71 - 71
1 Oct 2018
Bostrom MPG Jones CW Choi D Sun P Chui Y Lipman JD Lyman S Chiu Y
Full Access

Introduction

Custom flanged acetabular components (CFAC) have been shown to be effective in treating complex acetabular reconstructions in revision total hip arthroplasty (THA). However, the specific patient factors and CFAC design characteristics that affect the overall survivorship remain unclear. Once the surgeon opts to follow this treatment pathway, numerous decisions need to be made during the pre-operative design phase and during implantation, which may influence the ultimate success of CFAC. The goal of this study was to retrospectively review the entire cohort of CFAC cases performed at a large volume institution and to identify any patient, surgeon, or design factors that may be related to the long-term survival of these prostheses.

Methods

We reviewed 96 CFAC cases performed in 91 patients between 2004 and 2017, from which 36 variables were collected spanning patient demographics, pre-operative clinical and radiographic features, intraoperative information, and implant design characteristics. Patient demographics and relevant clinical features were collected from individual medical records. Radiographic review included analysis of pre-operative radiographs, computer tomographic (CT) scans, and serial post-operative radiographs. Radiographic failure was defined as loosening or gross migration as determined by a board-certified orthopedic surgeon. CFAC implant design characteristics and intra-operative features were collected from the design record, surgical record and post-operative radiograph for each case respectively.

Two sets of statistical analyses were performed with this dataset. First, univariate analyses were performed for each variable, comprising of a Pearson chi-square test for categorical variables and an independent t-test for continuous variables. Second, a random forest supervised machine learning method was applied to identify the most influential variables within the dataset, which were then used to perform a bivariable logistic regression to generate odds ratios. Statistical significance for this study was set at p < 0.05.


The Bone & Joint Journal
Vol. 100-B, Issue 4 | Pages 436 - 442
1 Apr 2018
Choi HG Lee YB Rhyu SH Kwon BC Lee JK

Aims

The aim of this study was to compare the rate of mortality and causes of death in Korean patients who undergo surgery for a fracture of the hip, up to 11 years after the injury, with a control group from the general population.

Materials and Methods

National cohort data from Korean Health Insurance Review and Assessment Service – National Sample Cohort were used. A ratio of 1:4 matched patients with a fracture who underwent surgery (3383, fracture group) between 2003 and 2012, and controls (13 532) were included. The matches were processed for age, gender, income, and region of residence. We also undertook analyses of subgroups according to age and gender. The mean follow-up was 4.45 years (1 to 11).


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 80 - 80
1 Jan 2018
Choi J Blackwell R Ismaily S Mallepally R Harris J Noble P
Full Access

Most patients presenting with loss of hip motion secondary to FAI have a combination of cam and pincer morphology. In this study, we present a composite index for predicting joint ROM based on anatomic parameters derived from both the femur and acetabulaum using a single reformatted CT slice.

Computer models of the hip joint were reconstructed from CT scans of 31 patients with mixed-type FAI (Average alpha angle: 73.6±11.1°, average LCE: 38.9±7.2°). The internal rotation of the hip at impingement was measured at 90° flexion using custom software. With the joint in neutral, a single slice perpendicular to the acetabular rim was taken at the 2 o'clock position. A set of 11 femoral and acetabular parameters measured from this slice were correlated with hip ROM using stepwise logistic regression.

Three anatomic parameters provided significant discrimination of cases impinging at <15 and >15 degrees IR: femoral anteversion (28%, p=0.026), the arc of anterior femoral head sphericity (10%, p=0.040), and the LCE in the 2 o'clock plane (10%, p=0.048). This led to the following definition of the Impingement Index: 0.16*(fem version) +0.11*(ant arc)−0.17*(LCE) which correctly classified 82% of cases investigated. None of the traditional parameters (e.g. alpha angle) were significantly correlated with ROM.

Our study has identified alternative morphologic parameters that could act as strong predictors of FAI in preoperative assessments. Using this information, each patient's individual risk of impingement may be estimated, regardless of the relative contributions of deformities of the femur and the acetabulum.


The Bone & Joint Journal
Vol. 98-B, Issue 10 | Pages 1355 - 1359
1 Oct 2016
Choi H Agrawal K Bedair H

Aims

We hypothesised that the synovial white blood cell (WBC) count in patients with a late periprosthetic joint infection (PJI) of the hip would depend on the duration of a patient’s symptoms, and that the optimal diagnostic threshold would also depend on this period of time.

Patients and Methods

The synovial WBC count and percentage of polymorphonuclear cells (%PMN), and the serum CRP and ESR levels obtained > six weeks after primary THA were compared between 50 infected and 88 non-infected THAs, and in patients with symptoms for more than or less than two weeks. Diagnostic thresholds for the synovial WBC count were calculated using area under the curve calculation.