to evaluate the efficacy and safety of topically applied tranexamic acid (TXA) in thoracolumbar spinal tuberculosis surgery, posterior approach. Thoracolumbar spine tuberculosis patients who requiring debridement, pedicle screw fixation and fusion surgery were divided into two groups. In the TXA group (n=50), the wound surface was soaked with TXA (1 g in 100 mL saline solution) for 3 minutes after exposure, after decompression, and before wound closure, and in the control group (n=116) using only saline. Intraoperative blood loss, drain volume 48 hours after surgery, amount of blood transfusion, transfusion rate, the haemoglobin, haematocrit after the surgery, the difference between them before and after the surgery, incision infection and the incidence of deep vein thrombosis between the two groupsAbstract
Objectives
Methods
To identify radiological patterns of compression (POC) of the spinal cord To develop a surgical protocol based on POC and determine its efficacy. To identify parameters predicting outcome of surgery
Pattern I – predominant one/two level compression in normal/narrow canal Pattern II – anterior &
posterior compression at one/ two levels (pincer cord) Pattern III – Three or more levels of predominant anterior compression with a normal canal Pattern III(A) – Pattern III in a patient with multiple medical co-morbidities Pattern IV – Three/more levels of anterior compression in narrow canal +/− posterior compression (beaded cord) Pattern IV(A) – Pattern IV with one/two level severe compression amongst the multiple anterior compressions. Mean follow-up was 3 yrs (2–8). ACDF was performed for patterns I, II &
III and posterior decompression for pattern IV and III(A). For pattern IV(A), a two stage primary posterior decompression followed by targeted ACDF at the site of maximal compression was performed. The clinical outcome was measured by modified JOA (mJOA) score, Hirayabashi Recovery Rate (HRR) and functional outcome by modified Neck Disability Index (NDI).