Prosthetic joint infections (PJIs) generate significant clinical and socio-economic pressures on the health service. Recent advances in the diagnosis of PJIs, with biomarkers and sonification have aided delineation of PJIs from aseptic processes. However these investigations are not widely available and expensive. Interface membrane histology has been shown to be superior to pseudocapsule histology; we therefore sought to ascertain the diagnostic benefit of deep canal sample microbiology in conjunction with standard pseudocapsule sampling. We performed a prospective study over a 20-month period as part of new multi-disciplinary approach to the management of suspected PJIs. 22 patients underwent 26 procedures at our institution where intra-operative deep canal samples were obtained concurrent to conventional pseudocapsule samples. These samples were cultured and analysed following our standardised microbiological methodology.Introduction
Patients/Materials & Methods
The technique of femoral cement-in-cement revision
is well established, but there are no previous series reporting its
use on the acetabular side at the time of revision total hip replacement.
We describe the technique and report the outcome of 60 consecutive
acetabular cement-in-cement revisions in 59 patients at a mean follow-up
of 8.5 years (5 to 12). All had a radiologically and clinically
well-fixed acetabular cement mantle at the time of revision. During
the follow-up 29 patients died, but no hips were lost to follow-up.
The two most common indications for acetabular revision were recurrent
dislocation (46, 77%) and to complement femoral revision (12, 20%). Of the 60 hips, there were two cases of aseptic loosening of
the acetabular component (3.3%) requiring re-revision. No other
hip was clinically or radiologically loose (96.7%) at the latest
follow-up. One hip was re-revised for infection, four for recurrent
dislocation and one for disarticulation of a constrained component.
At five years the Kaplan-Meier survival rate was 100% for aseptic
loosening and 92.2% (95% CI 84.8 to 99.6), with revision for any cause
as the endpoint. These results support the use of cement-in-cement revision on
the acetabular side in appropriate cases. Theoretical advantages
include preservation of bone stock, reduced operating time, reduced
risk of complications and durable fixation.