The video shows the detailed surgical technique of minimally invasive navigated total knee arthroplasty. A Columbus (BBraun Aesculap, Tuttlingen, Germany) total knee prosthesis is implanted using the OrthoPilot navigated system and the specially designed small MIOS instruments (BBraun Aesculap, Tuttlingen, Germany). A mini-mid-vastus approach is carried out with an 8 cm skin incision.