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Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 72 - 72
1 Feb 2020
Dwyer M Tumpowsky C Melnic C Bedair H
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Introduction

Despite the widespread use of opioids for pain control in post-operative joint arthroplasty patients, data regarding actual opioid consumption in opioid-naive patients during the recovery period are limited. We sought to determine postoperative opioid consumption for opioid-naïve patients undergoing total knee and hip arthroplasty (THA and TKA) procedures.

Methods

The study cohort consisted of 55 patients (29 females, 26 males) who underwent either primary unilateral TKA (n=28) or THA (n=27). Prior to discharge, patients were provided with a medication log on which to track daily consumption of pain medicine. Patients were asked to provide details regarding the type of pain medication, quantity and frequency of use, and pain score at the time of use. Patients were contacted weekly by a member of the study team to monitor compliance. Specific opioid prescription information was acquired for each subject using their electronic medical record. Subjects returned the completed logs once they ceased opioid use post-operatively. Daily quantity was converted to daily Morphine Equivalent Dose (MED). Average daily, weekly, and total post-operative use was calculated for all opioid data variables. Descriptive statistics (mean, frequency, deviation) were used to analyze opioid data. All dependent variables were compared between TKA and THA patients using separate independent samples t-tests or Chi-square tests.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 71 - 71
1 Feb 2020
Dwyer M Tumpowsky C Melnic C Bedair H
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Introduction

Opioids are an integral part of pain management following total joint replacement procedures; however, to date, no evidence-based guidelines which regulate opioid prescribing practices exist. In order to determine an appropriate number of opioids required to control pain for post-arthroplasty patients, it is important to understand why patients are using them. We sought to identify the causes of pain which necessitated opioid consumption for patients following total knee (TKA) and total hip (THA) arthroplasty.

Methods

The study cohort consisted of 55 patients (29 females, 26 males) who underwent either primary unilateral TKA (n=28) or THA (n=27). Prior to discharge, patients were provided with a pain diary in which to record details regarding the type of pain medication used, the time of use, pain score at the time of use, and the specific reason for use. Subjects returned the completed logs once they ceased opioid use post-operatively. Based on responses, we categorized reasons for use into either Activity, which was further classified into ADL and Exercise, or Rest, which was further classified into Sleeping, Sitting, and Laying Down. Average and frequency of opioid consumption was calculated for each category, along with the pain score at the time of use for each category. All dependent variables were compared between TKA and THA patients using separate independent samples t-tests or Chi-square tests.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 41 - 41
1 Feb 2020
Melnic C Aurigemma P Dwyer M Domingo-Johnson E Bedair H
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Background

Multiple retrospective studies have compared UC with traditional bearings and shown comparable results and outcomes when looking at clinical and radiologic variables, complications rates, and implant survivorship; however, debate still exists regarding the optimum bearing surface. The present study seeks to determine whether there are any preoperative patient demographic or medical factors or anatomic variables including femoral condylar offset and tibial slope that may predict use of a UC bearing when compared to a standard CR group.

Methods

The study cohort consisted of 117 patients (41 males, 76 females) who underwent primary TKA with the senior author. The implants utilized were either the CR or UC polyethylene components of the Zimmer Persona Total Knee System. Insert selection was based on intraoperative assessment of PCL integrity and soft tissue balancing. Patient demographics (age, gender, BMI) and co-morbidities (hypertension, diabetes, depression, cardiac disease, and lung disease) were recorded. Intraoperative variables of interest included extension and flexion range of motion, estimated blood loss (EBL), tourniquet time, and polyethylene and femoral component sizes. We calculated change in tibial slope and femoral condylar offset from pre- to post-surgery and computed the percentage of patients for whom an increase in tibial slope or femoral condylar offset was determined. Postoperative variables, including length of stay, complication rates and reoperation rates, were recorded. All dependent variables were compared between patients who received the UC component and patients who received the CR component. Continuous variables were assessed using independent samples t-tests, while categorical variables were compared using the chi-square test of independence.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 25 - 25
1 Mar 2017
Muratoglu O Suhardi V Bichara D Bedair H Oral E
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Introduction

The use of narcotic medications to manage postoperative pain after TJA has been associated with impaired mobility, diminished capacity to engage in rehabilitation, and lower patient satisfaction [1]. In addition, side effects including constipation, dizziness, nausea, vomiting and urinary retention can prolong post-operative hospital stays. Intraarticular administration of local anesthetics such as bupivacaine – part of a multimodal postoperative pain management regimen – reduces pain and lowers patients' length of stay [2]. In addition to its anesthetic activity, bupivacaine also has antibacterial activity, particularly against gram-positive bacteria [3]. We have developed a bupivacaine-eluting ultrahigh molecular weight polyethylene (Bupi-PE) formulation; we hypothesized that elution of bupivacaine from polyethylene could have both anesthetic and antibacterial effects in vivo.

Methods


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 53 - 53
1 Feb 2017
Bragdon C Barr C Madanat R Nielsen C Bedair H
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Introduction

A modern total knee replacement system was introduced in 2012 in order to improve the mechanics of total knee replacement (TKR). The purpose of this study was to assess the early clinical and radiographic outcomes of patients who have been treated with this modern TKR system at two years postoperatively.

Methods

Patients who received this TKR system between June of 2012 and September of 2014 were included in this prospective registry-based follow-up study. Demographics, component, and surgical data were collected. Radiographic outcomes were also assessed. Patient reported outcome measures (PROMs) of all patients with 2-year follow-up data were collected. Reasons for revision and overall survival at 2-years were evaluated.