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Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_10 | Pages 71 - 71
1 Oct 2022
Ferry T Arvieux C Stendel E Nich C Delobel P Zeller V Sotto A Dauchy F RONDE-OUSTAU C Tizon A
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Aim

To describe the management of PJI due to S. aureus in CRIOAcs in 2019 and to particularly focus on the evaluation of the efficacy of DAIR regarding control of infection and risk factors for failure up to 12 months.

Method

Thirteen CRIOAcs were selected to participate to the study. Data concerning the management of all the PJI in the year 2019 were retrospectively collected and registered in eCRFs. Inclusion criteria were: ≥ 18 years old patients with S. aureus ± other bacteria (in per surgical procedure sample); knee or hip PJI and with clinical signs of infection. Patients treated with bacteriophages were excluded. All eligible patients were notified by an information letter. Patients treated by the DAIR procedure were selected, and rate of control of infection (no inflammatory local signs or no new surgical procedure or no S. aureus in case of puncture) was analyzed using Kaplan Meier method and risk factors for failure at 12 months were assessed using Cox regression model.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_17 | Pages 1 - 1
1 Dec 2018
Wouthuyzen-Bakker M Sebillotte M Lomas J Kendrick B Palomares EB Murillo O Parvizi J Shohat N Reinoso JC Sánchez RE Fernandez-Sampedro M Senneville E Huotari K Allende JMB García AB Lora-Tamayo J Ferrari MC Vaznaisiene D Yusuf E Aboltins C Trebse R Salles MJ Benito N Vila A Del Toro MD Kramer T Petersdorf S Diaz-Brito V Tufan ZK Sanchez M Arvieux C Soriano A
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Aim

Late acute prosthetic joint infections (PJI) treated with surgical debridement and implant retention (DAIR) have a high failure rate. The aim of our study was to evaluate treatment outcome in late acute PJIs treated with DAIR versus implant removal.

Method

In a large multicenter study, late acute PJIs were retrospectively evaluated. Failure was defined as: PJI related death or the need for prosthesis removal or suppressive antibiotic therapy because of persistent or recurrent signs of infection. Late acute PJI was defined as < 3 weeks of symptoms more than 3 months after the index surgery.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_17 | Pages 92 - 92
1 Dec 2018
Wouthuyzen-Bakker M Sebillotte M Lomas J Taylor A Palomares EB Murillo O Parvizi J Shohat N Reinoso JC Sánchez RE Fernandez-Sampedro M Senneville E Huotari K Allende JB Garcia-Cañete J Lora-Tamayo J Ferrari MC Vaznaisiene D Yusuf E Aboltins C Trebse R Salles M Benito N Vila A Del Toro MD Kramer T Petershof S Diaz-Brito V Tufan ZK Sanchez M Arvieux C Soriano A
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Aim

Debridement, antibiotics and implant retention (DAIR) is the recommended treatment for all acute prosthetic joint infections (PJI). However, the efficacy of DAIR and identification of risk factors for failure in patients with late acute PJI, is not well described.

Method

Patients diagnosed with late acute PJI between 2005 and 2015 were retrospectively evaluated. Late acute PJI was defined as the development of acute symptoms (≤ 3 weeks) occurring ≥ 3 months after arthroplasty. Failure was defined as: i) the need for implant removal, ii) infection related death, iii) the need for suppressive antibiotic therapy due to persistent signs of infection and/or iv) relapse or reinfection during follow-up.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_22 | Pages 25 - 25
1 Dec 2017
Mahieu R Dubee V Ansart S Bernard L Gwenael LM Asseray N Arvieux C Ramanantsoa C Legrand E Abgueguen P
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Aim

The optimal treatment of streptococcal prosthetic joint infections (PJIs) is unclear. Poorer outcome has been associated with Streptococcus agalactiae species, comorbidities and polyethylene exchange for conservative approach. Rifampicin use may be associated with higher remission rate but results are sparse.

Method

A cohort of streptococcal PJI (including total hip arthroplasty –THA- or total knee arthroplasty –TKA-) was prospectively created and retrospectively reviewed in 7 reference centers for management of complex PJI between January 1, 2010 and December 31, 2012.