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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 491 - 491
1 Sep 2012
Rasmussen S Knudsen C Skou S Gronbech M Olesen J Rathleff M
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Introduction

Delayed onset muscle soreness (DOMS) in the quadriceps is frequent in runners finishing a marathon race, and may result in several days of discomfort and pain. There is an increasing clinical evidence that noninvasive, pulsed electromagnetic field therapy (PEMF) can have physiological effect on inflammation and tissue repair. The purpose of this pilot study was to investigate the effect of PEMF on quadriceps muscle soreness in marathon runners and to use the data to calculate an appropriate sample size for a subsequent study.

Material and methods

The design was a randomized double-blind prospective study covering a 5 days period after completion of a beach marathon. After the marathon all 74 runners that completed the 42.195 km were asked to participate in the study. Forty-six agreed to enter the study and were block randomized into an intervention group or a control group. The intervention group received an active pulsed electromagnetic field device, and the control group received a sham device. The sham devices were used in exactly the same manner but produced no electromagnetic field. The active PEMF device does not produce heat or cause any sensation in the tissue allowing participants to be blinded to treatment. The pulsed electromagnetic field signals of a 2-msec burst of 27.12-MHz sinusoidal waves were repeated at two bursts per second. Peak magnetic field was 0.05 G, which induced an average electric field of 10 mV/cm in the tissue with an effect of 7.3 mW/cm3. All subjects were instructed to place the device on the most painful area of the quadriceps for 20 minutes four times a day. Pain intensity was measured three times a day with the Visual Analogue Scale (VAS) during a 90o squat with a self-administered questionnaire. Data were non-parametric and compared with a two-sample Wilcoxon rank-sum test.


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 4 | Pages 497 - 503
1 May 2002
Hedström M åström K Sjöberg H Dalén N Sjöberg K Brosjö E

A total of 63 women who had an operation for a fracture of the hip was randomly allocated to one year of treatment either with anabolic steroids, vitamin D and calcium (anabolic group) or with calcium only (control group). The thigh muscle volume was measured by quantitative CT. The bone mineral density of the hip, femur and tibia was assessed by quantitative CT and dual-energy x-ray absorptiometry and of the heel by quantitative ultrasound. Quantitative CT showed that the anabolic group did not lose muscle volume during the first 12 months whereas the control group did (p< 0.01). There was less bone loss in the proximal tibia in the anabolic group than in the control group. The speed of gait and the Harris hip score were significantly better in the anabolic group after six and 12 months. Anabolic steroids, even in this moderate dose, given in combination with vitamin D and calcium had a beneficial effect on muscle volume, bone mineral density and clinical function in this group of elderly women