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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_3 | Pages 7 - 7
23 Jan 2024
Richards OJ Johansen A John M
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BACKGROUND. Theatre-listed trauma patients routinely require two ‘group and save’ blood-bank samples, in case they need perioperative transfusion. The Welsh Blood Service (WBS) need patients to have one recorded sample from any time in the last 10 years. A second sample, to permit cross-matching and blood issuing, must be within 7 days of transfusion (or within 48 hours if the patient is pregnant, or has been transfused within the last 3 months). The approximate cost of processing a sample is £15.00. AIM. To investigate whether routine pretransfusion blood sampling for trauma admissions exceeds requirements. METHODS. Electronic records were used to collect pretransfusion sampling data for all adult non-elective trauma patients listed for theatre under a trauma and orthopaedics consultant between 1/1/2023-31/1/2023. Data were collected on unnecessary samples, rejected samples and total excess samples. RESULTS. 113 patients (mean age[±SD] 64.09[±19.96]) underwent 132 procedures. On average, unnecessary sampling occurred at a rate of 0.48 samples per operation, equating to a cost of £945.00/month. Samples were rejected by the laboratory at a rate of 0.25 samples per operation. Common reasons for rejection were ‘patient date of birth discrepancy’ (between sample and request form), ‘patient address discrepancy’ and ‘signature discrepancy’. Overall, total excessive sampling occurred at a rate of 0.60 samples per operation. CONCLUSION. Nearly half of trauma patients undergo unnecessary blood testing in anticipation of potential perioperative transfusion. This has implications for sustainability, financial cost and patient welfare. This signals poor understanding of WBS requirements and is an area that requires improvement


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_15 | Pages 82 - 82
7 Nov 2023
Patel V Hayter E Hodgson H Barter R Anakwe R
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Extended patient waiting lists for assessment and treatment are widely reported for planned elective joint replacement surgery. The development of regionally based Elective Orthopaedic Centres, separate from units that provide acute, urgent or trauma care has been suggested as one solution to provide protected capacity and patient pathways. These centres will adopt protocolised care to allow high volume activity and increased day-case care. We report the plan to establish a new elective orthopaedic centre serving a population of 2.4 million people. A census conducted in 2022 identified that 15000 patients were awaiting joint replacement surgery with predictions for further increases in waiting times. The principle of care will be to offer routine primary arthroplasty surgery for low risk (ASA 1 and 2) patients at a new regional centre. Pre-operative assessment and preparation will be undertaken digitally, virtually and/or in person at local centres close to the where patients live. This requires new and integrated pathways and ways of working. Predicting which patients will require perioperative transfusion of blood products is an important safety and quality consideration for new pathways. We reviewed all cases of hip and knee arthroplasty surgery conducted at our centre over a 12-month period and identified pre-operative patient related predictive factors to allow us to predict the need for the perioperative transfusion of blood products. We examined patient sex, age, pre-operative haemaglobin and platelet count, use of anti-coagulants, weight and body mass index to allow us to construct the Imperial blood transfusion tool. We have used the results of our study and the transfusion tool to propose the patient pathway for the new regional elective orthopaedic centre which we present


Bone & Joint Open
Vol. 2, Issue 10 | Pages 850 - 857
19 Oct 2021
Blankstein AR Houston BL Fergusson DA Houston DS Rimmer E Bohm E Aziz M Garland A Doucette S Balshaw R Turgeon A Zarychanski R

Aims. Orthopaedic surgeries are complex, frequently performed procedures associated with significant haemorrhage and perioperative blood transfusion. Given refinements in surgical techniques and changes to transfusion practices, we aim to describe contemporary transfusion practices in orthopaedic surgery in order to inform perioperative planning and blood banking requirements. Methods. We performed a retrospective cohort study of adult patients who underwent orthopaedic surgery at four Canadian hospitals between 2014 and 2016. We studied all patients admitted to hospital for nonarthroscopic joint surgeries, amputations, and fracture surgeries. For each surgery and surgical subgroup, we characterized the proportion of patients who received red blood cell (RBC) transfusion, the mean/median number of RBC units transfused, and exposure to platelets and plasma. Results. Of the 14,584 included patients, the most commonly performed surgeries were knee arthroplasty (24.8%), hip arthroplasty (24.6%), and hip fracture surgery (17.4%). A total of 10.3% of patients received RBC transfusion; the proportion of patients receiving RBC transfusions varied widely based on the surgical subgroup (0.0% to 33.1%). Primary knee arthroplasty and hip arthroplasty, the two most common surgeries, were associated with in-hospital transfusion frequencies of 2.8% and 4.5%, respectively. RBC transfusion occurred in 25.0% of hip fracture surgeries, accounting for the greatest total number of RBC units transfused in our cohort (38.0% of all transfused RBC units). Platelet and plasma transfusions were uncommon. Conclusion. Orthopaedic surgeries were associated with variable rates of transfusion. The rate of RBC transfusion is highly dependent on the surgery type. Identifying surgeries with the highest transfusion rates, and further evaluation of factors that contribute to transfusion in identified at-risk populations, can serve to inform perioperative planning and blood bank requirements, and facilitate pre-emptive transfusion mitigation strategies. Cite this article: Bone Jt Open 2021;2(10):850–857


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 54 - 54
1 Mar 2013
Devadasan B
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Mini-incision total hip arthroplasty seeks to eliminate some complications of traditional extensile exposure and also facilitates more rapid post-operative rehabilitation. Posterior approach has been associated with increased risk of posterior dislocation. Thus, a modified mini-incision lateral approach of Hardinge was described not only to overcome this problem by preserving the posterior capsule, but also allows adequate access for orientation of the implant. The author has modified the Hardinge approach by a V-shaped incision where the apex is centered over the tip of the greater trochanter with the one limb extending proximally along the fibers of the gluteus medius muscle and the distal limb extending across the proximal part of vastus lateralis. This innovative surgical approach is described in this article. Conclusion. Larger incisions and surgical approaches have been associated with larger blood loss, greater need for perioperative transfusion, use of more postoperative analgesics, a longer hospital stay, and a slower recovery. In this modified approach, the gluteus medius is left intact. The postoperative strength of the abductors of the operated side was the same as that on the non-operated side and functionally, the direct lateral approach was a safe alternative to other approaches in decreasing the trendelenburg gait and incidence of heterotrophic ossification


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_5 | Pages 51 - 51
1 Mar 2017
Naseer Z Alexander C El Dafrawy M Okafor L Ponnusamy K Sterling R Skolasky R Khanuja H
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Background. Conflicting results about the impact of blood transfusions on outcomes after total knee arthroplasty (TKA) have been reported. We hypothesized that transfusions would be associated with greater readmission and complication rates after primary TKA. Methods. We conducted a retrospective cohort study of the 100% 2008 Medicare Provider Analysis and Review database, and identified primary THA patients by ICD9 codes and excluded fractures/ER admissions to select for elective cases. Patients who received a perioperative blood transfusion (6,951 patients) were compared to a control group who did not receive transfusion (332,762 patients). Descriptive statistics of age, sex, race, diagnosis for surgery, Elixhauser comorbidities, mortality (inpatient, 30, 60, and 90 days and 2 years), readmissions (30, 60, and 90 days), complications (medical and surgical at 30 and 90 days), and revision at 2 years were assessed for both groups. Continuous variables were compared with Student's T-test and categorical variables with chi-square test. Multivariate logistic regression models were constructed to assess the association of transfusion with readmissions, complications, and revisions. Statistical significance was set at p < 0.01. Results. Patients who received a transfusion were older (mean 74.4 vs. 72.6, p<0.0001), more likely to be male (75% vs. 66%, p<0.0001), and had a higher Elixhauser comorbidity count (2.0 vs. 1.85, p<0.0001). Transfused patients had significantly greater readmission rates at 30-days (8.2% vs 5.7%, p<0.0001), 60-days (11.7% vs 8.2%, p<0.0001), and 90-days (14.4% vs 10.4%, p<0.0001). Their overall complication rates at 30 days (2.1% vs 1.4%, p<0.0001) and 90 days (3.2% vs 2.1%, p<0.0001) were greater mainly due to greater surgical complications at 30 days (1.4% vs 0.9%, p<0.0001) and 90 days (2.1% vs 1.3%, p<0.0001). Patients who received a transfusion had significantly higher mortality rates at 2-years (2.2% vs. 1.4%, p<0.0001). Two years after discharge, transfused patients had no difference in revision rates (2.4% vs 2.4%, p=0.8805). Multivariate regression found that transfusion was the third most important factor for surgical complications at 30-days (OR: 1.6, 95% CI: 1.3 to 2.0) and an independent risk factor for readmissions at 60-days (OR: 1.4, 95% CI: 1.3 to 1.5). At 2-years, transfusion was independently associated with mortality (OR: 1.4, 95% CI: 1.2 to 1.7), but not revision (OR: 1.1, 95% CI: 0.9 to 1.3). Conclusion. Primary TKA patients who were transfused had an independently higher risk for surgical complications and readmissions at 30 and 90 days, and mortality within 2 years. Transfusion, however, did not impact revision rates. A restrictive transfusion threshold should be considered for patients undergoing TKA


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_27 | Pages 8 - 8
1 Jul 2013
Islam SU Davis N
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Surgery for DDH is one of the common paediatric orthopaedics procedures in a tertiary care paediatrics hospital. There are no uniformly agreed guidelines about the pre-operative work up related to blood transfusion in DDH surgery. This leads to lack of uniformity in practice, sometimes causes cancellations of operations on the day of surgery (due to no cross matched blood available) and on other occasions wastage of the cross matched blood. The aims of our study were to know the incidence of perioperative blood transfusion in a series of DDH operations and to determine what types of operations/kids have more chances of needing a blood transfusion peri-operatively. We included all children who had surgery for DDH between April 2009 and October 2012 in our institution. We found out which of these children had blood transfusion peri-operatively and reviewed their notes to determine any trends in transfusion requirements. 165 children had operations for DDH during the study period. This included operations ranging from hip open reduction to Ganz osteotomy. 6 out of 165 (4%) were transfused blood. Children needing blood transfusion tended to be older and had multiple hip operations previously. Only 3 (2 during Ganz and 1 during bilateral hip reconstruction) of these 6 children needed intra-operative blood transfusion. None of the under 4 years old children needed intra-operative blood transfusion. We conclude that children for unilateral primary hip operations for DDH do not need pre operative blood cross match. A group and save is enough in these cases


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLI | Pages 114 - 114
1 Sep 2012
Sisak K Hardy B Enninghorst N Balogh Z
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Geriatric hip fracture patients have a 14-fold higher 30-day mortality than their age matched peers. Up to 50% of these patients receive blood transfusion perioperatively. Both restrictive and liberal transfusion policies are controversial in this population. Aim: The longitudinal description of transfusion practice in geriatric hip fracture patients in a major trauma centre. An 8-year (2002–2009) retrospective study was performed on patients over the age of 65 undergoing hip fracture fixation. Yearly transfusion rate; the influence of transfusion on 30-day, 90-day and 1-year mortality and length of stay (LOS) was investigated. On admission haemoglobin (Hb), pre-transfusion Hb and post-transfusion Hb and their effect on transfusion requirement and mortality was also reviewed. The yearly changes in on-admission and pre-transfusion Hb were also examined. The influence of comorbidities, timing, procedure performed and operation duration on transfusion requirement and mortality was also studied. From the 3412 patients, 35% (1195) received transfusion during their hospital stay. There was no change in age, gender and co-morbidities during the study. Thirty-day mortality improved from 12.4% in 2002 to 7% in 2009. The transfusion rate showed a gradual decrease from the highest of 48.3% (2003) to 22.9% (2009) (Pearson correlation - R2 = −0.707, p=0.05). There was no change during the study period in on-admission and pre-transfusion Hb. The mortality for non-transfused and transfused patients was [9.6% vs. 10.3 % (30-day)], [17.2% vs. 18.4%(90-day)] and [27% vs. 30.5%(1-year), p=0.031]. LOS was 11±9 for non-transfused patients and 13±10 (p<0.001) for transfused patients. Patients with more comorbidities experienced a higher transfusion rate, (0 – 31%, 1 – 38%, 2 – 46%, 3 – 57%), (Pearson Chi-squared, p<0.001). The need for transfusion by different procedures in decreasing order was 47.6% intramedullary device, 44.0% DHS, 25.2% cemented hemiarthroplasty, 23.6% Austin-Moore, and 5.5% cannulated screws. The length of the operation increases the chance of transfusion (<1hrs, – 33%, 1–2hrs – 35%, 2–3hrs – 41%, >3 hours – 65%), (Pearson Chi-squared, p=0.010). Preoperative waiting time had no influence on transfusion frequency (<24hrs – 36%, 24–48hrs – 34%, 48–96hrs – 36%, >96hrs – 33%), (Pearson Chi-squared, p=0.823). The percentage of transfused geriatric hip fracture patients halved during the eight-year period without changes in demographics and co-morbidities. Perioperative transfusion of hip fracture patients is associated with higher 1-year mortality and increased LOS. A more restrictive transfusion practice has been safe and may be a factor in the improved 30-day mortality