Introduction. It was the purpose to evaluate the biomechanical changes that occur after optimal and non-optimal component placement of a hip resurfacing (SRA) by using a subject specific musculoskeletal model based on CT-scan data. Materials and Methods. Nineteen hips from 11 cadavers were resurfaced with a BHR using a femoral navigation system. CT images were acquired before and after surgery. Grey-value segmentation in Mimics produced contours representing the bone geometry and identifying the outlines of the 3 parts of the gluteus medius. The anatomical changes induced by the procedure were characterised by the translation of the hip joint center (HJCR) with respect to the pelvic and femoral bone. The contact forces during normal gait with ‘optimal’ component placement were calculated for a cement mantle of 3 mm, a socket inclination of 45° and anteversion of 15°. The biomechanical effect of ‘non-optimal placement’ was simulated by varying the positioning of the components. Results. There was a significant (p<0.01) shortening of the muscle length with the ‘optimal’ component placement for all parts of the gluteus medius with the largest shortening of the posterior part by 6mm. This was caused by a significant shortening of the femoral offset by 2.3mm (p<0.01). Because of a significant (p<0.01) medialisation of the HJCR by 4 mm, there was no significant increase in contact force. The hip joint contact forces increased by 0.5% per mm HJCR displacement. Each millimeter of cranial and lateral displacement of the femoral HJCR increased the contact force by 0.5% and 1%, respectively. The contact stresses changed significantly by 0.8% and 0.2% per degree of socket inclination and anteversion. The contact force increased 1% per mm lateral displacement of the acetabular HJCR. Discussion. Optimal placement of the SRA components did not completely restore the biomechanics of the native hip joint. The contact forces were not increased due to the compensatory effect of the medialisation of the acetabular HJCR. This suggests that reaming to the acetabular floor should be conducted in SRA. Femoral component displacement in the cranial and lateral direction significantly increased the hip joint loading. Errors of socket placement in the coronal and sagital plane significantly increased the contact stresses. Accumulative errors of both component displacements could lead to increased contact stresses of 18% to 23% with socket inclinations of 50° and 55°. Surgeons should reconsider continuing the SRA procedure if a neck length loss and lateralisation of the HCJR by >5 mm is anticipated as this would increase the contact stresses by >12%