PURPOSE. YouTube is a video sharing platform that is a common resource for patients seeking medical information. The objective of this study is to assess the educational quality of YouTube videos pertaining to total knee arthroplasty and knee arthritis. METHODS. A systematic search for the terms “knee replacement” and “knee arthritis” was performed using Youtube's search function. Data from the 60 most relevant videos were collected for each search term. Videos not in English or those without audio or captions were excluded. Quality assessment checklists with a scale of 0 to 10 points were developed to evaluate the video content. Videos were grouped into poor quality (grade 0–3), acceptable quality (grade 4–7) and excellent quality (grade 8– 10), respectively. Four independent reviewers assessed the videos using the same grading system and independently scored all videos. Discrepancies regarding the scoring were clarified by consensus discussion. RESULTS. Overall 106 videos were categorized. For videos regarding total knee replacements, the average number of views was 135,074 with an average duration of 14.53 minutes. Half of the videos were published by a physician or hospital sponsor and were for educational purposes. 64% of videos were of poor educational quality (32/50), 28% were of acceptable quality (14/50), and 8% were of good educational quality (4/50). Common missing information included discussion of surgical complications and implant duration. For videos regarding knee arthritis, the average number of views was 243,346 with an average duration of 4.97 minutes. 39% were published by a physician or hospital sponsor, with 64% of videos made for educational purposes. 66% of videos were of poor educational quality (37/56), 32% were of acceptable quality (18/56), and 2% were of good educational quality. The most common missing information were causes and risk factors for knee arthritis and long-term prognosis. CONCLUSIONS. The present study suggests that YouTube is a poor educational source for patients regarding knee arthroplasty and knee arthritis. Recognizing the limitations of YouTube as well as which topics are not commonly presented may guide clinicians to better educate their patients

The aim of the study was to investigate rotational behaviour of the arthritic knee before (preimplant) and after (postimplant) total knee replacement (TKR) using (image-free navigation system as a measurement tool which recorded the axial plane alignment between femur and tibia, in addition to the coronal and sagittal alignment as the knee is flexed through the range of motion. The data on the rotation of the arthritic knee was collected after the knee exposure and registration of the lower limb (preimplant data). The position of rotation between the femur and tibia was recorded in 30° flexion, 45°, 60°, 90° and maximum degrees of flexion of the knee. The data was divided into subsets of varus and valgus knees and these were analysed pre and postimplant for their rotational position using SPSS for statistics. The system was used in 117 knees of which 91 had full data set available (43 male 48 female). These included 71 varus knees, 16 valgus knees and 4 neutral knees to start in extension. Preimplant data analysis revealed there is tendency for the arthritic knees to first go in internal rotation in the initial part of flexion to 30 degrees and then the rotation is reversed back. This happens irrespective of the initial starting rotational relationship between femur and tibia in full extension. This happens in both varus as well as valgus arthritic knees. This trend of internal rotation in this initial part of flexion is followed in TKR as well implanted with fixed bearing CR knees irrespective of the preoperative deformity. Also noteworthy was the difference in rotation at 30°, 60° and 90 degrees of flexion between preimplant and postimplant knees (irrespective of varus and valgus groups). When calculated at different points of flexion, there was statistically significant difference in the change of rotation at each point of flexion except 45 degree of flexion. The pre-operative values of change in rotation (internal being positive) at each step from the extended position being 5.4° (SD 4.5°) at 30 ° flexion, 4.7°(5.2°) at 45°, 3.6°(6.1°) at 60°, 3.5°(7.2°) at 90° and 4.2°(8.3°) at maximum flexion. Corresponding post-operative rotations were 2.2°(4.8°), 4.1°(6.4°), 6.6°(7.3°), 9.9°(8.8°) and 7.7°(8.9°). There was also an increase in the total range of rotation that the knee goes through after it has been implanted with prosthesis although it may not happen in every knee. This is statistically significant (p value <0.001) and seems more so in valgus group. The rotational movements and interrelationship of the femur and tibia is a complex issue, especially in the arthritic knees. Preimplant arthritic knee behaved generally similarly to normal knees according to the literature. Normal gait pattern demonstrates that the tibia moved through a 4° to 8° arc of internal rotation relative to the femur. The overall range (10.2° =/−4.2°) of knee rotation in this study greater than 8° might be explained by preimplant data acquired after the knee was approached and therefore releasing knee soft tissue envelop. This study confirmed that during the first 30° both varus and valgus knees moved internally. In our study there is increased range of total rotation postimplant (14° =/−6.8°) which may be explained by the fact that the anterior cruciate ligament is lost in all the TKRs and the posterior cruciate ligament may be dysfunctional as well. Thus the constraints on the knee rotation are decreased postimplant leading to increased rotation. We found some difference between varus and valgus post implant knees in that internal rotation seen in initial 30 degrees of flexion is much more pronounced in valgus knees as compared to varus knees (p value <0.001). This study confirmed knee internal rotation in initial stages of flexion, preimplant in arthritic knees during a passive knee flexion assessment. Varus and valgus knee seemed to behave similarly. This mimics the normal knee rotation. Postimplant knees in TKR behave differently

Introduction. Septic knee arthritis with severe osteoarthritis (OA) presents challenging clinical situations because of unexpected and long time for treatment and less satisfactory clinical outcomes. Septic arthritis with damage to articular cartilage developed osteomyelitis (OM) frequently. Although arthroscopic debridement was the common treatment of septic arthritis, there was some limitation on the management of infected bone structures and then open arthrotomy should be reserved. In the patients of OM located only periarticular areas, the author used the PROSTALAC system for infected total knee arthroplasty (TKA) and achieved good results. Objectives. In periarticular OM with septic knee arthritis in patients with severe OA, we report the rate of control of infection using the PROSTALAC articulating spacer and to assess the clinical outcome after staged TKA. Methods. This study was conducted on a total of 11 patients (11 knees) treated for septic knee arthritis in patients with Kellgren-Lawrence classification grade 3–4 OA between April, 2014 and April, 2015. Of these, we retrospectively reviewed 6 knees of 6 patients (54.5%) who underwent staged TKA using the PROSTALAC articulating spacer. The inclusion criteria were periarticular OM confirmed by magnetic resonance imaging (MRI) and whole body bone scan (WBBS), affected bone could be resected and covered by the PROSTALAC system. There were 2 males and 4 females with a mean age of 64 years (range, 61 to 68 years). Prior to the initial surgery, the average erythrocyte sedimentation rate (ESR) 87mm/h, and C-reactive protein (CRP) 8.8 mg/dl. The mean follow-up period was 14 months (range, 12 to 24 months). For clinical assessment, WOMAC, UCLA, Patient Satisfaction scores and postoperative complications were evaluated. For radiological assessment, weight-bearing radiographs of the knee were obtained to evaluate bone change, component loosening, and recurrence of infection. Results. The mean interval between initial operation using the PROSTALAC system and staged TKA was 8.2 weeks (range, 8–10 weeks). The species could be identified in the culture of aspiration of joint fluid prior to the initial operation. The most frequently found etiologic agent was gram-positive cocci (66.6%), followed by MRSA (16.7%) and yeast like fungi (16.7%). At last review, ESR and CRP returned to normal and follow-up cultures were negative in all patients. We observed improvements in mean WOMAC, UCLA, and Patient Satisfaction scores at last review. Radiographs at final follow-up showed well-fixed implants with no radiographic evidence of loosening or infection. Conclusions. In this study, we observed a 100% microbiologic cure and 89% clinical cure in patients who underwent a staged TKA using the PROSTALAC system with a 14-months follow-up. This method appears to have several important advantages (1) there is less possibility of additional bone resection due to uncontrolled infection of adjacent bone; (2) there are possibly expected interval between two stages and more good patient satisfaction. The staged TKA using the PROSTALAC spacer would have a predictable, favorable effect on the control of infection and improvements in the functional outcomes for the treatment periarticular OM with septic knee arthritis in patients with severe arthritis

Aim. The aim of our study was to identify pathogens involved in septic knee arthritis after ACLR and to describe clinical features, treatment and outcome of infected patients. Methods. We conducted a retrospective observational study including all patients with ACLR infection in 3 orthopedic centers sharing the same infectious disease specialists. Results. During a seven-year period (2011–2017) we identified 74 infected patients among 9858 patients who had ACLR (incidence rate = 0.0075). Fourteen patients had polymicrobial infection. We identified 89 pathogens. Twenty four patients (34.4 %) were infected with S. aureus (27% of all isolates)(only one oxacillin-resistant strain). C. acnes was the second most frequent pathogen, identified in 14 patients (18.9%) (15.7% of all isolates). S. lugdunensis was identified in 9 patients (12.2%) (10.1% of all isolates). S. caprae was as frequent as S. epidermidis identified in 8 patients each (10.8%) (9 % of all isolates for each). No strain of S. lugdunensis and S. caprae was resistant to oxacillin, levofloxacin or rifampicin. Ten patients infected by C. acnes, 8 infected by S. lugdunensis, and 7 infected by S. caprae had an early acute infection. In all cases but one an arthroscopic lavage was performed, in 14 cases two lavages were required and in 4, 3 lavages. All patients infected by a strain susceptible to levofloxacin and rifampicin, including those with C. acnes, S. caprae and S. lugdunensis infection, were treated with an oral combination of levofloxacin and rifampicin, after a couple of days of IV empirical treatment with vancomycin and a broad spectrum beta-lactam. The median duration of treatment was 6 weeks. Seventy one patients were considered cured. Conclusions. To our knowledge this is the largest reported series of infection after ACLR. S. aureus is the main pathogen (27% of all strains). C. acnes, S. lugdunensis and S. caprae accounted for almost 35% of pathogens and 38% of infections. A conservative strategy consisting in arthroscopic lavage(s) and a 6-week treatment with levofloxacin and rifampicin was effective

Background. Septic knee arthritis is one of the most serious complications after total knee arthroplasty (TKA), and the effectiveness of its treatment affects the patient's quality of life. In our super-aging society, the frequency of TKA in the elderly, often combined with various comorbidities, is increasing. Careful management should be considerd during the management of septic arthritis after TKA in these patients. Purpose. To analyze the clinical features and outcomes of septic arthritis after TKA in our institution. Materials and Methods. Between April 1999 and March 2014, 534 TKAs (osteoarthritis [OA]; 381, rheumatoid arthritis [RA]; 154) were performed. Of these patients, 8 with post-operative infected TKA were retrospectively surveyed. Results. The TKA-associated infection rates were 0.83% (0.35%, OA; 1.7%, RA) during the study period. Five male and 3 female patients were included, with a mean age of 68 years (range, 39–88 years) and primary diagnoses of OA (5) and RA (3). Malignant rheumatoid arthritis (MRA) was present in 1 patient. The infection was affected by a comorbidity in 2 (diabetes mellitus and mixed connective tissue disease). Microorganisms were detectable in 7 patients (methicillin-resistant Staphylococcus aureus [MRSA], 1; methicillin-sensitive Staphylococcus aureus, 2; Streptococcus pyogens, 1; Streptococcus oralis, 1; Escherichia coli, 1; Staphylococcus epidermidis, 1; and unknown, 1) (Fig. 1). The use of the Segawa/Leone classification resulted in 5 patients with type III (acute hematogenous) and 3 with type IV (late) infections. Four patients with type III (80%) infection underwent open debridement, continuous irrigation, and successful implant retention (Fig. 2). The MRA patient had type III infection and an MRSA infection that was treated with two-stage revision, but the infection recurred. We could not perform a re-implantation, and resection arthroplasty was needed. Arthroscopic irrigation in 1 patient with type III infection ended in failure, and open debridement was required. We attempted to retain the implant in 1 patient with type IV infection, but implant removal was required. Three patients with type IV infection underwent two-stage revision successfully. Discussion. The post-TKA infection rate was 0.83% in our institution. Of the implants, 50% (type III, 80%; type IV, 0%) were successfully retained. Early open debridement and irrigation are important for implant retention in patients with infected TKAs, while arthroscopic debridement does not appear to be effective for infected TKA. Implant retention was difficult in the presence of resistant microorganisms. Two-stage revision was required in patients with type IV infection, with a success rate of 75%

We hypothesize that tethering adhesions of the quadriceps muscle are the major pathological structures responsible for a limited range of motion in the stiff arthritic knee. Forty-two modified quadriceps muscle releases were performed on 24 patients with advanced osteoarthritis scheduled for total knee arthroplasty. The ranges of motion were documented intraoperatively both before and immediately after the release. Passive flexion improved significantly in all patients (mean, 32.4 degrees of improvement, P < .001) following a modified quadriceps release, despite any presence of osteophytes or severe deformities. These results strongly implicate adhesions of the quadriceps muscle to the underlying femur, which prevent the distal excursion of the quadriceps tendon, as the restrictive pathology preventing deep flexion in patients with osteoarthritis

The lifetime prevalence of symptomatic osteoarthritis at the knee is 50% osteoarthritis of the ankle occurs in only 1% of the population. This variation in prevalence has been hypothesised to result from the differential responsiveness of the joint cartilages to catabolic stimuli. Human cartilage explants were taken from the talar domes (n=12) and the femoral condyles (n=7) following surgical amputation. Explants were cultured in the presence of either a combination of high concentration cytokines (TNFα, OSM, IL-1α) to resemble a post traumatic environment or low concentration cytokines to resemble a chronic osteoarthritic joint. Cartilage breakdown was measured by the percentage loss of Sulphated glycosaminoglycan (sGAG) from the explant to the media during culture. Expression levels of the pro-inflammatory molecules nitric oxide and prostaglandin E. 2. were also measured. Significantly more sGAG was lost from knee cartilage exposed to TNFα (22.2% vs 13.2%, P=0.01) and TNFα in combination with IL-1α (27.5% vs 16.0%, P=0.02) compared to the ankle; low cytokine concentrations did not affect sGAG release. Significantly more PGE. 2. was produced by knee cartilage compared to ankle cartilage however no significant difference in nitrite production was noted. Cartilage from the knee and ankle has a divergent response to stimulation by pro-inflammatory cytokines, with high concentrations of TNFα alone, or in combination with IL-1α amplifying cartilage degeneration. This differential response may account for the high prevalence of knee arthritis compared to ankle OA and provide a future pharmacological target to treat post traumatic arthritis of the knee

Aim

Traditionally, serum white blood count (WBC), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) have been utilized as markers to evaluate septic arthritis (SA). Recently, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been identified as prognostic factors for treatment failure, mortality and morbidity in various clinical settings. To date, these markers have not been utilized for evaluating outcomes after hip and knee SA.

Thus, the purpose of this study was to determine the ability of admission NLR and PLR to predict treatment failure and postoperative 90-day mortality in hip and knee SA.

Osteotomies are performed in patients with lower limb malalignment, usually associated with osteoarthritis of the knee or instability. The surgery realigns the mechanical axis of the leg by either an opening or closing wedge procedure with the goal of decreasing symptoms, improving function, and delaying the progression of osteoarthritis.

The 103 patients that had undergone osteotomy surgery were studied prospectively, and data was analysed one year post surgery. We examined subjective outcomes, patient history and surgical variables using backwards stepwise multiple regression models to determine whether there were any associations between these.

Subjective outcomes from a total of 103 osteotomy patients at one year post surgery were compared to patient history and surgical variables. All categories of KOOS and WOMAC scores were improved after surgery.

The multivariate models showed that variables significantly influencing the outcomes were pre-operative flexion, pre-operative weight, the size of the HTO plate used and tourniquet time.

Greater pre-operative flexion; lower weight; larger plate used, indicating larger corrections; and lower tourniquet times were shown to result in improved scores. Not all variables influenced all categories of the scores. While flexion and pre-operative weight influenced across the categories of both scores, plate size influenced KOOS pain and symptoms and tourniquet time influenced KOOS sport and quality of life.

Knee flexion and body weight were the most influential variables when considering KOOS and WOMAC outcome scores as a measure of success. The size of the correction may have influenced the pain and symptom scores because patients with greater malalignment may have initially had worse symptoms and their perception of their current function and pain is affected by their previous levels of pain and function. Osteotomy results in improved function and pain scores and our results indicate that there are several variables which significantly influence patient outcomes and may be of greater importance than other variables.

Proximal femoral focal deficiency is a congenital disorder of malformation of the proximal femur and/or the acetabulum. Patients present with limb length discrepancy and clinical features along a spectrum of severity. As these patients progress through to skeletal maturity and on to adulthood, altered biomechanical demands lead to progression of arthropathy in any joint within the lower limb. Abnormal anatomy presents a challenge to surgeons and conventional approaches and implants may not necessarily be applicable. We present a case of a 62-year-old lady with unilateral proximal femoral focal deficiency (suspected Aitken Class A) who ambulated with an equinus prosthesis for her entire life. She presented with ipsilateral knee pain and instability due to knee arthritis but could not tolerate a total knee arthroplasty due to poor quadriceps control. A custom osteointegration prosthesis was inserted with a view to converting to the proximal segment to a total hip replacement if required. The patient went on to develop ipsilateral symptomatic hip arthritis but altered acetabular anatomy required a custom tri-flange component (Ossis, Christchurch, New Zealand) and a custom proximal femoral component to link with the existing osseointegration component (Osseointegration Group of Australia, Sydney, Australia) were designed and implanted. The 18 month follow up of the custom hip components showed that the patient had Oxford hip scores that were markedly improved from pre-operatively. Knee joint heights were successfully restored to equal when the patient's prosthesis was attached. The patient describes feeling like “a normal person”, walks unaided for short distances and can ambulate longer distances with crutches. Advances in design and manufacture of implants have empowered surgeons to offer life improving treatments to patients with challenging anatomy. Using a custom acetabular tri-flange and osseointegration components is one possible solution to address symptomatic ipsilateral hip and knee arthropathy in the context of PFFD in adulthood

Introduction. Transtibial osseointegration (TFOI) for amputees has limited but clear literature identifying superior quality of life and mobility versus a socketed prosthesis. Some amputees have knee arthritis that would be relieved by a total knee replacement (TKR). No other group has reported performing a TKR in association with TTOI (TKR+TTOI). We report the outcomes of nine patients who had TKR+TTOI, followed for an average 6.5 years. Materials & Methods. Our osseointegration registry was retrospectively reviewed to identify all patients who had TTOI and who also had TKR, performed at least two years prior. Four patients had TKR first the TTOI, four patients had simultaneous TKR+TTOI, and one patient had 1 OI first then TKR. All constructs were in continuity from hinged TKR to the prosthetic limb. Outcomes were: complications prompting surgical intervention, and changes in daily prosthesis wear hours, Questionnaire for Persons with a Transfemoral Amputation (QTFA), and Short Form 36 (SF36). All patients had clinical follow-up, but two patients did not have complete survey and mobility tests at both time periods. Results. Six (67%) were male, average age 51.2±14.7 years. All primary amputations were performed to manage traumatic injury or its sequelae. No patients died. Five patients (56%) developed infection leading to eventual transfemoral amputation 36.0±15.3 months later, and 1 patient had a single debridement six years after TTOI with no additional surgery in the subsequent two years. All patients who had transfemoral amputation elected for and received transfemoral osseointegration, and no infections occurred, although one patient sustained a periprosthetic fracture which was managed with internal fixation and implant retention and walks independently. The proportion of patients who wore their prosthesis at least 8 hours daily was 5/9=56%, versus 7/9=78% (p=.620). Even after proximal level amputation, the QTFA scores improved versus prior to TKR+TTOI, although not significantly: Global (45.2±20.3 vs 66.7±27.6, p=.179), Problem (39.8±19.8 vs 21.5±16.8, p=.205), Mobility (54.8±28.1 vs 67.7±25.0, p=.356). SF36 changes were also non-significant: Mental (58.6±7.0 vs 46.1±11.0, p=.068), Physical (34.3±6.1 vs 35.2±13.7, p=.904). Conclusions. TKR+TTOI presents a high risk for eventual infection prompting subsequent transfemoral amputation. Although none of these patients died, in general, TKR infection can lead to patient mortality. Given the exceptional benefit to preserving the knee joint to preserve amputee mobility and quality of life, it would be devastating to flatly force transtibial amputees with severe degenerative knee joint pain and unable to use a socket prosthesis to choose between TTOI but a painful knee, or preemptive transfemoral amputation for transfemoral osseointegration. Therefore, TTOI for patients who also request TKR must be considered cautiously. Given that this frequency of infection does not occur in patients who have total hip replacement in association with transfemoral osseointegration, the underlying issue may not be that linked joint replacement with osseointegrated limb replacement is incompatible, but may require further consideration of biological barriers to ascending infection and/or significant changes to implant design, surgical technique, or other yet-uncertain factors

There are many reasons that the surgically inclined orthopaedic surgeon should be responsible for the medical management of osteoarthritis of the knee. These include: 1) The non-operative treatment of OA is often highly effective for all stages of the disease; 2) A non-operative treatment program is the best preparation for a successful surgical outcome; and 3) Patients appreciate a surgeon's interest in their overall care and are likely to return if surgery is needed; 4) Medicare and many insurance companies are refusing to pay for a TJA until many months of conservative management has been administered. There are many potential causes of pain in an arthritic knee. These include intra-articular (e.g. degenerative meniscal tears, loose bodies, synovitis) and extra-articular (tendonitis, e.g. ilio-tibial band syndrome, bursitis, muscle overload syndromes and referred pain) sites. The potential sources of pain in an arthritic knee produce a wide range of symptoms that are not necessarily correlated with objective measurements (e.g. x-rays, MRI). Moreover, the natural history of an arthritic knee is unpredictable and variable. The treatment of the young, arthritic knee patient of all stages requires a systematic and consistent non-surgical approach. This approach includes the use of: 1) analgesics/anti-inflammatory agents; 2) activity modification; 3) alternative therapies; 4) exercise; 5) injections/lavage. The response to each form of non-surgical treatment is unpredictable at each stage (Kellgren 1–4) of OA. The placebo effect of each form of treatment, including the physician-patient interaction, is 50–60% in patients with mild-moderate OA. The components of a non-operative treatment program include: 1) Education-emphasizing the importance of the patient taking charge of his/her care; 2) Appropriate activity/life style modifications-emphasizing the importance of remaining active while avoiding activities that aggravate symptoms (e.g. running to biking); 3) Medications-oral, topical, intra-articular; 4) Physical therapy. There are extensive data to support each of these interventions. The AAOS has issued guidelines based upon a review of the literature-based effectiveness of conservative interventions

There are many reasons that the surgically inclined orthopaedic surgeon should be responsible for the medical management of osteoarthritis of the knee. These include: 1) The nonoperative treatment of OA is often highly effective for all stages of the disease; 2) A nonoperative treatment program is the best preparation for a successful surgical outcome; and 3) Patients appreciate a surgeon's interest in their overall care and are likely to return if surgery is needed; 4) Medicare and many insurance companies are refusing to pay for a TJA until many months of conservative management has been administered. There are many potential causes of pain in an arthritic knee. These include intra-articular (e.g. degenerative meniscal tears, loose bodies, synovitis) and extra-articular (tendonitis, e.g. ilio-tibial band syndrome, bursitis, muscle overload syndromes and referred pain) sites. The potential sources of pain in an arthritic knee produce a wide range of symptoms that are not necessarily correlated with objective measurements (e.g. x-rays, MRI). Moreover, the natural history of an arthritic knee is unpredictable and variable. The treatment of the young, arthritic knee patient of all stages requires a systematic and consistent non-surgical approach. This approach includes the use of: 1) analgesics/anti-inflammatory agents; 2) activity modification; 3) alternative therapies; 4) exercise; 5) injections/lavage. The response to each form of non-surgical treatment is unpredictable at each stage (Kellgren 1–4) of OA. The placebo effect of each from of treatment, including the physician-patient interaction, is 50–60% in patients with mild-moderate OA. The components of a nonoperative treatment program include: 1) Education-emphasising the importance of the patient taking charge of his/her care; 2) Appropriate activity/life style modifications-emphasising the importance of remaining active while avoiding activities that aggravate symptoms (e.g. running to biking); 3) medications-oral, topical, intra-articular; 4) Physical therapy. There are extensive data to support each of these interventions. The AAOS has issued guidelines highlighted the literature based effectiveness of conservative interventions

Patient specific instrumentation (PSI) for elective knee replacements in arthritic knees with severe deformities and in revision scenarios is becoming increasingly popular due to the advantage of restoring the limb axes, improved theatre efficiency and outcomes. Currently available systems use CT scan or MRI for pre-operative templating for design considerations with varied accuracy for sizing of implants. We prospectively evaluated 200 knees in 188 patients with arthritic knees with deformities requiring serial clinical assessment, radiographs and CT scans for PSI templating for TruMatch knee system (DepuySynthes, Leeds, UK). The common indications included severe arthritic deformities, previous limb fractures and in obese limbs with difficult clinical assessment. Surgical procedure was performed on standard lines with the customised cutting blocks. The ‘lead up’ time between the implant request and the operating date was 5 weeks on an average. We compared the pre op CT images and the best fit post-operative x- rays. The sizing accuracy for femur and tibia was 98.93 % and 95.75% respectively. All blocks fitted the femur and tibia. There were no bail outs, no cutting block breakage, 1 patient had residual deformity of 20 degrees, and 1 patient had late infection. The length of hospital stay, economic viability in terms of theatre turnover, less operating time, cost of sterilisation in comparison to conventional knee replacement surgery with other factors being unchanged was also assessed. The projected savings was substantial along with improved geometrical restoration of the knee anatomy. We recommend the use of PSI based on CT scan templating in difficult arthritic knees

Introduction. Arthritic knees requiring total knee replacement may present with additional deformities located along the femur or tibia away from the articular region. These deformities may be congenital, developmental, associated with metabolic bone disease, or acquired as a result of malunited fractures or previous advocated for arthritic knee with ipsilateral extra-articular deformity. Methods. We undertook retrospective study to evaluate the results of total knee arthroplasty in arthritic knee with extra-articular deformity in 26 knees (24 patients). Sixteen deformities were in tibia and ten deformities were in femur. All patients underwent total knee arthroplasty with intraarticular bone resection and soft tissue balancing. Results. Average period of follow up was 30 months. Average preoperative arc of motion was 57.5 degrees, which improved to 102.5 degrees. The average preoperative knee society knee score 23.5 points, which improved to an average of 91.3 points at the time of last follow up. The average functional score was 27.0 points, which improved to average of 88.0 points. There were no complications such as infection, ligament instability or component loosening. Conclusion. Intra-articular bone resection is an effective procedure for management of arthritic knees with extra-articular deformity

Background. Artificial total knee designs have revolutionized over time, yet 20% of the population still report dissatisfaction. The standard implants fail to replicate native knee kinematic functionality due to mismatch of condylar surfaces and non-anatomically placed implantation. (Daggett et al 2016; Saigo et al 2017). It is essential that the implant surface matches the native knee to prevent Instability and soft tissue impingement. Our goal is to use computational modeling to determine the ideal shapes and orientations of anatomically-shaped components and test the accuracy of fit of component surfaces. Methods. One hundred MRI scans of knees with early osteoarthritis were obtained from the NIH Osteoarthritis Initiative, converted into 3D meshes, and aligned via an anatomic coordinate system algorithm. Geomagic Design X software was used to determine the average anterior-posterior (AP) length. Each knee was then scaled in three dimensions to match the average AP length. Geomagic's least-squares algorithm was used to create an average surface model. This method was validated by generating a statistical shaped model using principal component analysis (PCA) to compare to the least square's method. The averaged knee surface was used to design component system sizing schemes of 1, 3, 5, and 7 (fig 1). A further fifty arthritic knees were modeled to test the accuracy of fit for all component sizing schemes. Standard deviation maps were created using Geomagic to analyze the error of fit of the implant surface compared to the native femur surface. Results. The average shape model derived from Principal Component Analysis had a discrepancy of 0.01mm and a standard deviation of 0.05mm when compared to Geomagic least squares. The bearing surfaces showed a very close fit within both models with minimal errors at the sides of the epicondylar line (fig 2). The surface components were lined up posteriorly and distally on the 50 femurs. Statistical Analysis of the mesh deviation maps between the femoral condylar surface and the components showed a decrease in deviation with a larger number of sizes reducing from 1.5 mm for a 1-size system to 0.88 mm for a 7-size system (table 1). The femoral components of a 5 or 7-size system showed the best fit less than 1mm. The main mismatch was on the superior patella flange, with maximum projection or undercut of 2 millimeters. Discussion and Conclusion. The study showed an approach to total knee design and technique for a more accurate reproduction of a normal knee. A 5 to 7 size system was sufficient, but with two widths for each size to avoid overhang. Components based on the average anatomic shapes were an accurate fit on the bearing surfaces, but surgery to 1-millimeter accuracy was needed. The results showed that an accurate match of the femoral bearing surfaces could be achieved to better than 1 millimeter if the component geometry was based on that of the average femur. For any figures or tables, please contact the authors directly

Genu recurvatum deformity is uncommon in arthritic knees undergoing total knee arthroplasty (TKA). We retrospectively analysed radiographs and navigation data to determine the clinical and radiographic results of computer-assisted TKA in knee arthritis with recurvatum deformity. Based on alignment data obtained during computer assisted (CAS) TKA, 40 arthritic knees (36 patients) with a recurvatum deformity of at least 5° were identified. The mean recurvatum deformity was 8.7° (6° to 14°). On preoperative standing hip-ankle radiographs, 23 limbs (57.5%) had a mean varus deformity of 169.4° (153° to 178°) and 17 limbs had a mean valgus deformity of 189.2° (182° to 224°). The intraoperative navigation data showed mean tibial resection of 7.5mm (4.6 to 13.4mm) and distal femur resection of 7.5mm (3.3 to 13mm) with a mean final extension gap of 21.2mm and a flexion gap at 90° of 21.1mm and on extension. On table, the mean knee deformity in sagittal plane was 3° flexion (1.5° to 4.5° flexion). Postoperatively, the mean HKA angle on standing hip-ankle radiographs was 179.2° (177° to 182°). On postoperative lateral radiographs, joint line in extension was moved distally in 35 limbs by 2.3mm (0.3 to 4mm) and proximally in 5 limbs by 2.2mm (2.2 to 2.4mm); the mean preoperative posterior femoral offset of 28.7 mm changed to 27.9 mm postoperatively. At a mean follow up 28 months (14- 48 months) the knee, function, and pain scores improved by 61, 48, and 28 points, respectively and there was no recurrence of recurvatum deformity at final follow up. Genu recurvatum is a notoriously difficult condition to address at TKA. The challenges are to be able to detect it at surgery and take appropriate measures in terms of resection and releases to correct it satisfactorily. Computer assisted TKA helps to achieve excellent deformity correction, limb alignment, gap balancing and function in patients with recurvatum deformity by accurately quantifying and helping to modify the amount of bone cuts and titrate soft tissue release

Numerous studies have demonstrated that concomitant lower back pain (LBP) results in worse functional outcomes in patients undergoing surgical treatment for the management of end stage hip and knee arthritis. However, no equivalent studies have analysed the impact of back pain on the outcomes of patients with end stage ankle arthritis. Furthermore, given that two widely accepted surgical options exist in the treatment of ankle arthritis, namely total ankle arthroplasty (TAA) and ankle arthrodesis (AA), it is possible that one surgical technique may be superior in patients with LBP. The aim of this study was to determine the incidence of LBP in people with ankle arthritis, analyse its effect on functional outcomes, and explore whether there was a treatment advantage from either TAA or AA. Prospectively collected data from the Canadian Orthopaedic Foot and Ankle Society (COFAS) database of ankle arthritis was analysed in this study. All patients with ankle arthritis who underwent surgery performed by three fellowship-trained foot and ankle surgeons at a single institution between January 2003 and July 2012 were studied. Patient demographics were collected pre-operatively, including the absence or presence of back pain, and post-operative follow up was performed at 2 and 5 years, evaluating patient-reported functional outcome measures including the Ankle Arthritis Score (AAS) and the 36-item short form survey (SF-36). Using a linear regression model, a multivariate analysis was performed to examine the relationship between back pain, TAAs and AAs. In total, 451 patients were studied. 164 patients (36.4%) presented with concomitant LBP. At presentation, the LBP group had worse AAS scores (54.8 vs 57.8 p. At 2 years postoperatively, the AAS score was the same in both groups (28.9 vs 26.8 p = 0.3), but patients with LBP had worse SF-36 PCS (42.1 vs 36.6 p 0.05) in any of the functional outcome scores at 2 or 5 years post-operatively. The results of this study suggest there is no advantage of TAA over AA in the treatment of ankle arthritis in patients with concomitant lower back pain. Although pre-operative back pain resulted in worse SF-36 outcomes at 2 and 5 years post- operatively, this was not the case for AAS scores

While no one would argue the necessary role for the medical management of patients with early knee arthritis, significant controversy remains regarding the ideal treatment for a patient with bone-on-bone osteoarthritis who could equally be treated with a high tibial osteotomy, a uni-compartmental total knee, potentially a patello-femoral replacement if dealing with isolated patello-femoral disease or lastly, a complete total knee replacement. While clearly to date there has not been consensus on this issue, a review of the arguments, both pro and con, should be used as a guide to the surgeon in making this clinical judgment. 1. Patient Satisfaction.- Many ardent supporters of uni-compartmental knee replacements espouse one of the principle benefits of the uni knee as much greater patient satisfaction. Unfortunately, what is never taken into account is the pre-selection bias that occurs in this patient population. Patients with the most minimal amount of arthritis and those with the greatest range of motion are pre-selected to undergo a uni-compartmental knee replacement compared to the more advanced arthritic knee with mal-alignment and more significant pre-operative disability that will undergo a total knee replacement. Additionally the sources of data to draw the conclusions must be carefully analyzed. We must avoid using data from small series with unblinded patients performed by surgeons expert in the technique. Instead registry data, with its broad based applicability, is a much more logical source of information. Of significance, when over 27,000 patients were assessed regarding satisfaction following knee surgery; there was no difference in proportions of satisfied patients whether they had a total knee or a uni-compartmental knee. 2. Implant Longevity - Once again large prospective cohort data in the form of arthroplasty registries strongly favors total knee arthroplasty over uni-compartmental knee arthroplasty. The Swedish Knee Arthroplasty Registry demonstrated higher revision rates with uni's as compared with total knee replacements. In the Australian Joint Replacement Registry the cumulative 13-year percent revision rate for primary total knee replacements is 6.8% and for uni-compartmental knee replacements is 15.5%. Higher failure rates in uni-compartmental knee replacements seen in Australia has correlated to a significant decrease in the number of uni's being performed, which peaked at 15.1% in 2003 and in 2014 has reduced to 4.7%. There is a direct correlation to age, with younger patients having a significantly higher percentage of revision following uni-compartmental knee replacements (25% failure rate at 11 years if less than 55 years old). There is also tremendous variability in the success rate of the uni in the Australian Registry depending on the implant design (5 year cumulative revision rate range 5.0% to 18.9%), which is simply not seen in the total knee replacement population (5 year cumulative revision rate range 1.6% to 7.7%). While one can perform the philosophical exercise of debating the merits of a total knee versus uni-compartmental knee, the evidence is overwhelming that in the hands of the masses a total knee replacement patient will have equal satisfaction to a uni-compartmental patient, and will enjoy a much lower probability of revision in the short term and in the long term

While no one would argue the necessary role for the medical management of patients with early knee arthritis, significant controversy remains regarding the ideal treatment for a patient with bone-on-bone osteoarthritis who could equally be treated with a high tibial osteotomy, a uni-compartmental total knee, potentially a patello-femoral replacement if dealing with isolated patello-femoral disease or lastly, a complete total knee replacement. While clearly to date there has not been consensus on this issue, a review of the arguments, both pro and con, should be used as a guide to the surgeon in making this clinical judgment. Patient Satisfaction: Many ardent supporters of uni-compartmental knee replacements espouse one of the principle benefits of the uni knee as much greater patient satisfaction. Unfortunately, what is never taken into account is the pre-selection bias that occurs in this patient population. Patients with the most minimal amount of arthritis and those with the greatest range of motion are pre-selected to undergo a uni-compartmental knee replacement compared to the more advanced arthritic knee with mal-alignment and more significant preoperative disability that will undergo a total knee replacement. Additionally the sources of data to draw the conclusions must be carefully analyzed. We must avoid using data from small series with unblinded patients performed by surgeons expert in the technique. Instead registry data, with its broad based applicability, is a much more logical source of information. Of significance, when over 27,000 patients were assessed regarding satisfaction following knee surgery; there was no difference in proportions of satisfied patients whether they had a total knee or a uni-compartmental knee. Implant Longevity: Once again large prospective cohort data in the form of arthroplasty registries strongly favors total knee arthroplasty over uni-compartmental knee arthroplasty. The Swedish Knee Arthroplasty Registry demonstrated higher revision rates with uni's as compared with total knee replacements. In the Australian Joint Replacement Registry the cumulative 13 year percent revision rate for primary total knee replacements is 6.8% and for uni-compartmental knee replacements is 15.5%. Higher failure rates in uni-compartmental knee replacements seen in Australia has correlated to a significant decrease in the number of uni's being performed, which peaked at 15.1% in 2003 and in 2014 has reduced to 4.7%. There is a direct correlation to age, with younger patients having a significantly higher percentage of revision following uni-compartmental knee replacements (25% failure rate at 11 years if less than 55 years old). There is also tremendous variability in the success rate of the uni in the Australian Registry depending on the implant design (5 year cumulative revision rate range 5.0% to 18.9%), which is simply not seen in the total knee replacement population (5 year cumulative revision rate range 1.6% to 7.7%). While one can perform the philosophical exercise of debating the merits of a total knee versus uni-compartmental knee, the evidence is overwhelming that in the hands of the masses a total knee replacement patient will have equal satisfaction to a uni-compartmental patient, and will enjoy a much lower probability of revision in the short term and in the long term