Introduction. Although surgical remedies tend to be the long-term solutions for patients with osteoarthritis (OA), many alternatives exist that offer the potential to slow progression, alleviate pain, and/or restore function. One such option is the unloader OA knee brace. The objective of this study was to assess the in vivo medial joint space narrowing with and without the brace during weight-bearing portion of gait. Methods. Twenty subjects were evaluated after being clinically assessed by a single surgeon to be bone-on-bone on the medial side. In vivo gait kinematics were collected using a validated 3D-to-2D fluoroscopic registration technique (Figure 1). Subjects were asked to first walk on a treadmill without a brace (Figure 2), and then, after a qualified technician fit a properly sized brace to each subject, they were asked to walk again (Figure 3). In vivo fluoroscopic images were captured and registered at heel-strike (HS) and mid stance (MS) for both scenarios. CT scans were used to acquire the patient-specific bone models that were used in the registration process. Results. All twenty subjects experienced a positive increase in medial joint space and verbally stated their knee pain lessened while wearing the brace. The average medial joint space change was 1.7±0.8 mm (3.1 max, 0.3 min) at HS and 1.6±0.8 mm (3.7 max, 0.4 min) at MS (Figure 4). Five patients experienced more than 2.5 mm of medial joint space change when wearing the unloader brace, indicating substantial effectiveness of the brace. Conclusion. While previous unloader brace studies have focused on outcome scores and patient satisfaction to analyze brace effectiveness, this study quantifiably demonstrated improvement in joint space narrowing due to the unloader brace. These results suggest that unloader braces may provide benefit in the interim when symptoms of OA are present prior to need for surgical intervention. For any figures or tables, please contact the authors directly

Scaphoid fractures are a common injury accounting for more than 58% of all carpal bone fractures(1,2). Biomechanical studies have suggested that scaphoid mal-union may lead to altered carpal contact mechanics causing decreased motion, pain and arthritis(1,2). The severity of mal-union required to cause deleterious effects has yet to be established. This limits the ability to define surgical indications or impacts on prevention of posttraumatic arthritis. Computed tomography has been shown to be a useful in determining the 3D implications of altered bony alignment on the joint contact mechanics of surrounding joints. The objective of this study was to report mid-term follow-up image-based outcomes of patients with scaphoid mal-unions to determine the extent to which arthritic changes and decreased joint space is present after a minimum of 4 years following fracture. Participants (n=14) who had previously presented with a mal-united scaphoid fracture (indicated by a Height:Length Ratio >0.6) between November 2005 and November 2013 were identified and contacted. A short-arm thumb spica case was used to treat X patients and X required surgical management. Baseline and follow-up CT images, were performed with the wrist in radial deviation and positioned such that the long axis of the scaphoid was perpendicular to the axis of the scanner. Three-dimensional inter-bone distance (joint space), a measure of joint congruency and 3D alignment, was quantified from reconstructed CT bone models of the distal radius, scaphoid, lunate, capitate, trapezium and trapezoid from both the baseline and follow-up scans(3). Repeated measures ANOVA was used to detect differences in contact area (mm2) between baseline and follow-up CT's for the radioscaphoid, scaphocapitate and scaphotrapezium-trapezoid joint. The average age of participants was 43.1 years (16–64 years old). There was significant loss of joint space, indicated by a greater joint contact area 3–4 years post fracture, between baseline and follow-up reconstruction models, at the scaphocapitate (mean difference: 21.5±146mm2, p=0.007) and scaphotrapezoid joints (mean difference: 18.4 ±28.6mm2, 0.042). Significant differences in the measured contact area was not found for the radioscaphoid (0.153) and scaphotrapezium joints (0.72). Additionally, the scaphoid, qualitatively, appears to track in the vorsal direction in the majority of patients following fracture. Increased joint contact area in the scaphocapitate and scaphotrapezoid joint 3–4 years following fracture results from decreased 3D joint space and overall narrowing. Joint space narrowing, while not significantly different for all joints examined, was reduced for all joints surrounding the scaphoid. Decreased joint space and increased contact area detectable within this short interval might be suggestive of a trajectory for developing arthritis in the longer term, and illustrates the potential value of these measures for early detection. Longer term follow-up and correlation to clinical outcomes are needed to determine the importance of early joint space narrowing, and to identify those most at risk

Purpose. The outcome of idiopathic chondrolysis in South Africa has been reported as a progressive downhill course resulting in a painful, stiff hip (Jones 1971, Sparks&Dall 1982). The cause of the disease remains unknown. Theories suggested are mechanical (decreased movement with loss of synovial nutrition; increased joint pressure) and an auto-immune response in genetically predisposed individuals. Our experience with continuous passive motion (CPM) and anti-inflammatory treatment has been disappointing. Method. In order to improve our understanding of the disease and our results, we prospectively studied 5 consecutive patients. All the patients had a subtotal capsulectomy (Roy&Crawford 1988) to relieve intra-articular pressure and correction of the flexion and abduction deformities. Post-operative treatment was with anti-inflammatories and CPM. Results. The patients were adolescent females between 10 and 12.5 years old. They presented with stiff, painful hips with flexion, abduction and external rotation deformities. They had normal auto-immune markers. Radiographs revealed osteopenia and joint space narrowing. CT confirmed osteopenia and joint space narrowing. Three patients had subchondral erosions (two on either side of the joint and one on the acetabular side only). MRI showed bone oedema and confirmed the erosions. Histology of the synovium showed non-specific chronic inflammation with lymphocyte and plasma cell infiltration suggesting an auto-immune cause. Histology of the cartilage showed a superficial layer of fibrous tissue, then a layer of degenerate chondrocytes, with normal chondrocytes in the deep layer. Post-operatively patients had improved range of motion. At mean follow up of 7.8 months the patients had a repeat MRI to assess cartilage regeneration. NO DISCLOSURES

Rapidly progressive osteoarthritis of the hip (RPOH) is an unusual subset of osteoarthritis. It is characterized by rapid joint space loss, chondroly­sis, and sometimes marked femoral head and acetabular destruction as a late finding. The exact pathogenetic mechanism is unknown. Potential causes of RPOH include subchondral insufficiency fracture resulting from osteoporosis, increasing posterior pelvic tilt as a mechanical factor, and high serum levels of matrix metalloproteinase (MMP)-3 as biological factors. This study was aimed to identify some markers that associate with the destructive process of RPOH by analyzing the proposed pathological factors of the disease, MMP-3, pelvic tilt, and osteoporosis. Of female patients who visited our hospital with hip pain from 2012 through 2018, this study enrolled female patients with sufficient clinical records including the onset of hip pain, age and body mass index (BMI) at the onset, a series of radiographs during the period of >12 months from the onset of hip pain, and hematological data of MMP-3 and C-reactive protein (CRP). We found the hip joints of 31 patients meet the diagnostic criteria of RPOH, chondrolysis >two mm in one year, or 50% joint space narrowing in one year. Those patients were classified into two groups, 17 and 14 patients with and without subsequent femoral head destruction in one year shown by computed tomography, respectively. Serum MMP-3 and CRP were measured with blood samples within one year after the hip pain onset. The cortical thickness index (CTI) as an indicator of osteoporosis and pelvic tilt parameters were evaluated on the initial anteroposterior radiograph of the hip. These factors were statistically compared between the two groups. This study excluded male patients because RPOH occurs mainly in elderly females and the reference intervals of MMP-3 are different between males and females. There was no difference in age at onset or bone mass index between the RPOH patients with and without subsequent femoral head destruction. Serum levels of MMP-3 were significantly higher in the RPOH patients with the destruction (152.1 ± 108.9 ng/ml) than those without the destruction (66.8 ± 27.9 ng/ml) (P = 0.005 by Mann-Whitney test). We also found increased CRP in the patients with femoral head destruction (0.725 ± 1.44 mg/dl) compared with those without the destruction (0.178 ± 0.187 mg/dl) (P = 0.032 by Mann-Whitney test). No difference in the duration between the hip pain onset and the blood examination was found between the two groups. There was no significant difference in CTI or pelvic tilt between the two groups. The pathological condition that may increase serum MMP-3 and CRP could be involved in femoral head destruction after chondrolysis of the hip in patients with RPOH

Longstanding un-united scaphoid fractures or scapholunate insufficiency can progress to degenerative wrist osteoarthritis (termed scaphoid non-union advanced collapse (SNAC) or scapho-lunate advanced collapse (SLAC) respectively). Scaphoid excision and partial wrist fusion is a well-established procedure for the surgical treatment of this condition. In this study we present a novel technique and mid-term results, where fusion is reserved for the luno-capitate and triquetro-hamate joints, commonly referred to as bicolumnar fusion. The purpose of this study was to report functional and radiological outcomes in a series of patients who underwent this surgical technique. This was a prospective study of 23 consecutive patients (25 wrists) who underwent a bicolumnar carpal fusion from January 2014 to January 2017 due to a stage 2 or 3 SNAC/SLAC wrist, with a minimum follow-up of one year. In all cases two retrograde cannulated headless compression screws were used for inter-carpal fixation. The clinical assessment consisted of range of motion, grip and pinch strength that were compared with the unaffected contralateral side where possible. Patient-reported outcome measures, including the DASH and PRWE scores were analysed. The radiographic assessment parameters consisted of fusion state and the appearance of the radio-lunate joint space. We also examined the relationship between the capito-lunate fusion angle and wrist range of motion, comparing wrists fused with a capito-lunate angle greater than 20° of extension with wrists fused in a neutral position. The average follow-up was 2.9 years. The mean wrist extension was 41°, flexion 36° and radial-ulnar deviation arc was 43° (70%, 52% and 63% of contralateral side respectively). Grip strength was 40 kg and pinch strength was 8.9 kg, both 93% of contralateral side. Residual pain for activities of daily living was 1.4 (VAS). The mean DASH and PRWE scores were 19±16 and 29±18 respectively. There were three cases of non-union (fusion rate of 88%). Two wrists were converted to total wrist arthroplasty and one partial fusion was revised and healed successfully. Patients with an extended capito-lunate fusion angle trended toward more wrist extension but this did not reach statistical significance (P= 0.07). Wrist flexion did not differ between groups. Radio-lunate joint space narrowing progressed in 2 patients but did not affect their functional outcome. After bicolumnar carpal fusion using retrograde headless screws, patients in this series maintained a functional flexion-extension arc of motion, with grip-pinch strength that was close to normal. These functional outcomes and fusion rates were comparable with standard 4-corner fusion technique. A capito-lunate fusion angle greater than 20° may provide more wrist extension but further investigation is required to establish this effect. This technique has the advantage that compression screws are placed in a retrograde fashion, which does not violate the proximal articular surface of the lunate, preserving the residual load-bearing articulation. Moreover, the hardware is completely contained, with no revision surgery for hardware removal required in this series

Introduction. Diagnosis of osteoarthritis relies primarily on image-based analyses. X-ray, CT, and MRI can be used to evaluate various features associated with OA including joint space narrowing, deformity, articular cartilage integrity, and other joint parameters. While effective, these exams are costly, may expose the patient to ionizing radiation, and are often conducted under passive, non-weightbearing conditions. A supplemental form of analysis utilizing vibroarthrographic (VAG) signals provides an alternative that is safer and more cost-effective for the patient. The objective of this study is to correlate the kinematic patterns of normal, diseased (pre-operative), and implanted (post-operative) hip subjects to their VAG signals that were collected and to more specifically, determine if a correlation exists between femoral head center displacement and vibration signal features. Methods. Of the 28 hips that were evaluated, 10 were normal, 10 were diseased, and 8 were implanted. To collect the VAG signal from each subject, two uniaxial accelerometers were placed on bony landmarks near the joint; one was placed on the greater trochanter of the femur and the other along the anterior edge of the iliac crest. The subjects performed a single cycle gait (stance and swing phase) activity under fluoroscopic surveillance. The CAD models of the implanted components were supplied by the sponsoring company while the subject bone models were created from CT scans. 3D-to-2D registration was conducted on subject fluoroscopic images to obtain kinematics, contact area, and femoral center head displacement. The VAG signals were trimmed to time, passed with a denoise filter and wavelet decomposition. Results. When comparing the femoral head displacement to the vibration signals with respect to the normal hips, insignificant magnitudes of vibration were present (0.05 volts). For the diseased hips, greater magnitudes were seen (0.2 volts). For the implanted subjects, the overall vibration features were small (0.05 volts) much like the signals from the normal hips except for spikes that correlated to features within the gait cycle. Therefore, grinding sounds were heard from the degenerative hips, but not present for the normal or implanted hips in this study. Discussion. In regards to the normal hip subjects, the lesser magnitude of volts correlated well with the kinematic results showing no separation of the femoral head center (1 mm). For the diseased hips, the instances of greater feature quantity occurred at moments where the subjects experienced higher values of head center displacement (1 mm). These subjects also had an overall increase in average voltage magnitude likely due to the loss of cartilage about the articulating surface resulting in a rougher surface for the accelerometers to record. For the implanted subjects, due to no head center displacement and a smoother surface for joint articulation, the vibration signals were smaller than the diseased case but showed better correlation with features within the gait cycle. No exact quantification has been determined between separation and accelerometer voltage output, further studies and testing will need to be carried out in order to reach such a conclusion. For any figures or tables, please contact authors directly

Introduction. The purpose of this study was to demonstrate postoperative improvement and high satisfaction rates after a surgical approach that includes arthroscopic labral repair only, in patients with borderline dysplasia, without instability. Methods. Between September 2009 and December 2011, patients less than 50 years old who underwent hip arthroscopy for symptomatic intra-articular hip disorders, with a lateral center-edge (CE) angle between 20 and 25, were included in this study. Patients with Tönnis grade 2 or greater, hip joint space narrowing, severe hip dysplasia (CE〈20), hip joint instability and Legg-Calve-Perthes disease were excluded. Patient-reported outcome scores, including the modified Harris Hip Score (mHHS), Western Ontario and McMaster Universities Arthritis index (WOMAC), and visual analog scale (VAS) for pain were obtained in all patients preoperatively and at 1, 2, and 3 years postoperatively. Results. A total of 36 patients met the criteria to be included in the study. Of these, 32 (88.8%) patients were available for follow-up. There was a significant improvement in mHHS from 67.19±7.66 to 82.69±6.95 (P<0.001), and WOMAC score from 58.90±5.77 to 77.90±6.38 (P<0.001). There was a significant improvement in VAS scores from 5.8 to 2.9 (P<0.001). There was a significant improvement in range of motion, flexion from 108.44±7.77 to 115.31±6.08 (P<0.001) and external rotation from 29.06±5.74 to 33.13±4.88 (P<0.001). Conclusions. The current study demonstrates favorable results in borderline dysplasia hip without instability at minimum 3-year follow-up for an arthroscopic approach that includes labral repair. Labrum is the main key-stone structure, which should be preserved in borderline dysplasia hip for functional and pain improvement. Also the prognosis of treatment is probably forecasted more by the nature of stability and the intra-articular pathology rather than simply the presence or absence of radiographic finding of borderline dysplasia

Purpose. The purpose of this study was to demonstrate postoperative improvement and high satisfaction rates after a surgical approach that includes arthroscopic labral repair only, in patients with borderline dysplasia, without instability. Methods. Between September 2009 and December 2011, patients less than 50 years old who underwent hip arthroscopy for symptomatic intra-articular hip disorders, with a lateral center-edge (CE) angle between 20 and 25, were included in this study. Patients with Tönnis grade 2 or greater, hip joint space narrowing, severe hip dysplasia, hip joint instability and Legg-Calve-Perthes disease were excluded. Patient-reported outcome scores, including the modified Harris Hip Score (mHHS), Western Ontario and McMaster Universities Arthritis index (WOMAC), and visual analog scale (VAS) for pain were obtained in all patients preoperatively and at 1, 2, and 3 years postoperatively. Results. A total of 36 patients met the criteria to be included in the study. Of these, 32 (88.8%) patients were available for follow-up. There was a significant improvement in mHHS from 67.19 ± 7.66 to 82.69 ± 6.95 (P<0.05), WOMAC score from 58.90 ± 5.77 to 77.90 ± 6.38 (P<0.05), and VAS scores from 5.8 ± 0.88 to 2.9 ± 0.62 (P<0.05). There was a also improvement in range of motion, flexion from 108.44 ± 7.77 to 115.31 ± 6.08 (P<0.05) and external rotation from 29.06 ± 5.74 to 33.13 ± 4.88 (P<0.05). Conclusions. The current study demonstrates favorable results in borderline dysplasia hip without instability at minimum 3-year follow-up for an arthroscopic approach that includes labral repair. Labrum is the main key-stone structure, which should be preserved in borderline dysplasia hip for functional and pain improvement

Introduction. The first carpometacarpal (CMC) joint is the second most common joint of the hand affected by degenerative osteoarthritis (OA). 1. Laxity of ligamentous stabilizers that attach the first metacarpal bone (MC1) and the trapezium bone (TZ), notably the volar anterior oblique ligament (AOL), has been associated with cartilage wear, joint space narrowing, osteophyte formation, and dorsal-radial CMC subluxation. 2. In addition, the proximal-volar end of the MC1 has a bony prominence known as the palmar lip (PL) that adds conformity to this double-saddle joint, and is thought to be a supplemental dorsal stabilizer. Currently, no study has looked at the changes to the 3D shape and relative positions of these structures with OA. Methods. CT scans of patients with clinically diagnosed CMC OA (n=11, mean age 73 [60–97], 8 females) and CT scans of ‘normal’ patients with no documented history of CMC OA (n=11, mean age 37 [20–51], 6 females) were obtained with the hand in a prone position. 3D reconstructions of the MC1 and TZ bones were created, and each assigned a coordinate system. 3. The long axis of the MC1 and the proximal-distal axis of the TZ were established, and the location where they intersected the CMC articular surface was defined as their articular center points, X and O, respectively (Figure 1). Using the TZ as a fixed reference, we calculated the relative position of X in the dorsal-ventral and radial-ulnar directions. A two sample t-test was performed to compare the normal and OA groups. In addition, the distal position of the PL relative to X was recorded. Results. The dorsal position of the MC1 relative to the TZ was significantly greater (p=0.002) in the OA group compared with the normal group, with mean dorsal positions of 7.1 and 3.2mm, respectively (Figure 2). The distal position of the PL relative to X was also significantly greater (p=0.001) in the OA group when compared with the normal group, with mean positions of 5.8 and 1.9mm, respectively (Figure 3). Discussion. Dorsal migration of the MC1 in the OA group would suggest a compromised AOL, known to be elongated or absent intraoperatively. Without a sufficient AOL, the PL was positioned more distally in the OA group, as the load on the PL during extension activities could possibly exceed cartilage strength resulting in subchondral bone remodeling and further joint degeneration. We did not observe radial migration of the MC1 bone possibly due to the presence of bony osteophytes that can reduce abduction-adduction function in OA patients. 4. The relationship discovered between OA and changes to bone morphology and relative bone positions of the CMC joint may provide further insight into the natural progression of this disease

Background. The optimal treatment for symptomatic elbow osteoarthritis remains debatable especially in patients still involved in heavy manual work. The Outerbridge-Kashiwagi (OK) procedure has been used when simple measures fail. The aim of this study is to analyse the results of the OK procedure in patients with symptomatic osteoarthritis. Methods. Twenty-two patients were included in the study. The male:female ratio was 18:4. The mean age was 60 years with mean follow-up of 38 months (24–60 months). 17 were manual workers, 3 involved in sports activities and 2 non-manual workers. All patients were assessed using Mayo Elbow Performance Index Score system. Preoperative radiological assessment showed osteophytes around olecranon and coronoid process and joint space narrowing in radio-humeral articulationin all cases. Results. There was a significant improvement (p<0.05) in movement in the flexion-extension axis from 78.2° to 107.3°. There was a significant reduction in pain post-operatively (p<0.001). Mean MEPI score improved from 50 to 87.4 post surgery which was significant (p<0.05). One patient had ulnar nerve palsy which resolved in six months with conservative management. The results were excellent in six patients (27%), good in fifteen (68%), fair in one (5%) and one (5%) had poor result. Discussion and conclusion. The present study indicates that the OK procedure provides significant pain relief and a functionally useful range of movement of more than 100°. The procedure can be used in high demand patients, wherein total elbow replacement is not indicated. It significantly reduces the disability in patients with significant elbow arthritis

Achieving a primary outcome with revision UKR is possible but it depends on an understanding of the main failure modes and avoiding the obvious pitfalls. The most common failure mode in the long term is lateral compartment progression at 2.5% at 28 years. The most common failure overall is misdiagnosis of a painful radiolucency leading to unnecessary revision. There are a number of potential pitfalls:. Do not revise for unexplained pain. 75% of patients will go on to fail because of continuing pain. A distinction must be made to differentiate between a physiological radiolucency (with a narrow lucency accompanied by a sclerotic margin which is normal) and a pathological radiolucency (with a poorly defined lucency without surrounding sclerotic margin which is indicative of loosening and/or infection). Femoral loosening can present with subtle findings. Flexion/extension views are helpful to diagnose this problem. Wear can be a problem with fixed bearing in the second decade and can present with subtle findings. Infection can present with contralateral compartment joint space narrowing. The approach and exposure is usually straightforward and component removal is generally easy. Tibial resection is undertaken referenced from the normal lateral condyle removing 10mm of bone. Femoral preparation is generally straightforward but care must be taken to dial in correct rotation in the absence of the posterior medial condyle which was resected in the first operation. Generally a CR or PS primary implant is used with 2–4mm extra polyethylene thickness than is used in primary case. Revision for infection and stress fracture led to difficult revisions where revision components are usually required. The results for Revision UKR approach those of a primary procedure in all cases except revision for unexplained pain, infection and a stress fracture

Purpose. To analyze the effectiveness of a vancomycin impregnated calcium sulfate cement bead insertion after debridement (of) an acute-immediate stage infected hip arthroplasty. Materials and Methods. Between 2002 and 2008, 13 patients with documented acute-immediate stage infection of hip arthroplasty were reviewed and followed for at least two years postoperatively(average 4.3 years). The preoperative and postoperative clinical and radiologic findings and blood laboratory work were checked. All cases were performed through retention of the implant and massive debridement and saline irrigation. After that a vancomycin impregnated calcium sulfate cement beads was inserted. Results. After the first operation, the average interval for second operation was 27.7 days (17–37). At the second operation, the erythrocyte sediment rate and C-reactive protein were 150.97 mm/hr (34.6 ∼339.7 mm/hr) and 76.4 mg/L (41∼132 mg/L) respectively. Infectious organism were cultured and isolated. There were 5 cases of Methicillin resistant staphylococcus aureus (MRSA). In addition, results of an antibiotics sensitivity test were 8 cases of Vancomycin, and 5 cases of 3rd generation Cephalosporin. Radiologic results showed 10 cases with stable fixation on last follow-up (femoral stem) and 1 case of hip joint space narrowing, acetabular erosion. Conclusion. Vancomycin impregnated, calcium sulfate, cement bead insertion for an acute immediate infection of hip arthroplasty proved to be a useful method

Perthes disease often leaves young adults with hip joint incongruency due to femoral head asphericity, (extra-articular extrusion and superior flattening). This causes femoro-acetabular impingement, a reduced range of movement and early degenerative change. We report a novel method for restoration of femoral head sphericity and femoro-acetabular congruency. Two males (aged 21 and 22 years) presented with groin pain and severe hip stiffness after childhood Perthes disease. Imaging confirmed characteristic saddle shaped deformities of the femoral head, with cartilage loss overlying a central depression in the superior section of the head. A new method of treatment was proposed. Both cases were treated in the same manner. A surgical dislocation was performed with a trochanteric flip osteotomy. The extra-articular bump was removed with osteotomes and a burr to reduce femoro- acetabular impingement. The sphericity of the femoral head was restored using a HemiCap partial re-surfacing (Arthrosurface, MA, USA). The radius of the implant was selected to match that of the acetabulum. Restoration of the height of the flattened portion of the weight-bearing surface of the femoral head reduces abnormal loading of the acetabular articular cartilage by improving congruency of the joint. Both patients recovered without incident and were mobilised with crutches, restricted to touch weight-bearing for six weeks to protect union of the trochanteric osteotomy. At a minimum of three year follow-up both patients had sustained improved range of movement, pain and Oxford hip score. Repeated imaging shows no evidence of joint space narrowing or loosening at this stage. We conclude that this novel treatment functions well in the short term. Further surveillance is on-going to confirm that this treatment results in improved long term durability of the natural hip joint after Perthes disease

In order to manage painful subluxation/dislocation secondary to cerebral palsy, 12 hips in 11 patients received combined femoral and Chiari pelvic osteotomies with additional soft tissues releases at an average age of 14.1 (9.1-17.8) years. Pain relief, improvement in the arc of movement, sitting posture and ease of perineal care was recorded in all, and these features have been maintained at an average follow-up of 13.1 (8-17.5) years. The improvement of general mobility was marginal, but those who were community walkers benefited the most. Pre-operative radiological measurements have been modified post-operatively to use lateral margin of the neo-acetabulum produced by the pelvic osteotomy. The radiological migration index improved from a mean of 80.6% to 13.7% [p<0.0001]. The mean changes in CE angle and Sharp's angle were 72° (range 56°- 87°) [p<0.0001] and 12.3° (range 9°- 15.6°) [p< 0.0001] respectively. Radiological evidence of progressive arthritic change was seen in only one hip, in which only a partial reduction had been achieved, and there was early joint space narrowing in another. Heterotopic ossification was observed in one patient with athetoid quadriplegia who remained pain free. In seven hips the lateral Kawamura approach, elevating the greater trochanter, provided exposure for both osteotomies and allowed the construction of a dome-shaped iliac osteotomy, while protecting the sciatic nerve. This combined procedure provides a stable hip with sustained pain relief for the adolescent and young adult presenting with pain

The aim of our study was to assess, for the first time in a large study, whether there are radiological features of the acromioclavicular joint (ACJ) which vary with age or between genders and side. Clinical experience suggested that there was no clear correlation between the radiological features and symptoms arising from the ACJ. Therefore we also aimed to test the null hypothesis that there are no consistent radiological features which correspond with the need for surgical excision of the ACJ. We analysed 240 shoulder radiographs, divided into male and female, left and right shoulders, and decades from 20 to 80 years inclusive. At the ACJ the presence of sclerosis, osteophytes, cysts and lysis were recorded, and the width of the joint measured. These same parameters were assessed on the pre-operative radiographs for a group of 100 patients by a blinded observer. Fifty had undergone ASD (arthroscopic subacromial decompression), and 50 ASD with ACJ excision. These two groups were age matched. Statistical analyses were performed. There was no statistical difference between any of the parameters for gender or side however with increasing age there was a significantly increased incidence of joint space narrowing and increased features of osteoarthrosis. When comparing the matched ASD and the ACJ excision groups it was found that the presence of medial sclerosis (p = 0.016) and superior clavicular osteophytes (p = 0.016) were more common in the ACJ excision group. We concluded that there is a change in the radiological features of the ACJ with increasing age but not between sides or gender. The null hypothesis is upheld. Only 2 parameters, namely medial acromial sclerosis and superior clavicular osteophytes, are radiological features which correlate with a symptomatic acromioclavicular joint. These have poor sensitivity and specificity and therefore should not be used as a test

Purpose. It is well known that meniscus extrusion is associated with structural progression of knee OA. However, it is unknown whether medial meniscus extrusion promotes cartilage loss in specific femorotibial subregions, or whether it is associated with a increase in cartilage thickness loss throughout the entire femorotibial compartment. We applied quantitative MRI-based measurements of subregional cartilage thickness (change) and meniscus position, to address the above question in knees with and without radiographic joint space narrowing (JSN). Methods. 60 participants with unilateral medial OARSI JSN grade 1–3, and contralateral knee OARSI JSN grade 0 were drawn from the Osteoarthritis Initiative. Manual segmentation of the medial tibial and weight-bearing medial femoral cartilage was performed, using baseline and 1-year follow-up sagittal double echo steady-state (DESS) MRI, and proprietary software (Chondrometrics GmbH, Ainring, Germany). Segmentation of the entire medial meniscus was performed with the same software, using baseline coronal DESS images. Longitudinal cartilage loss was computed for 5 tibial (central, external, internal, anterior, posterior) and 3 femoral (central, external, internal) subregions. Meniscus position was determined as the % area of the entire meniscus extruding the tibial plateau medially and the distance between the external meniscus border and the tibial cartilage in an image located 4mm posterior to the central image (a location commonly used for semi-quantitative meniscus scoring). The relationship between meniscus position and cartilage loss was assessed using Pearson (r) correlation coefficients, for knees with JSN and without JSN. Results. The percentage of knees showing a quantitative value of >3mm medial meniscus extrusion was 50% in JSN knees, and only 12% in noJSN knees. The 1-year cartilage loss in the medial femorotibial compartment was 74±182µm (2.0%) in JSN knees, and 26±120µm (0.8%) in noJSN knees. There was a significant correlation between cartilage loss throughout the entire femorotibial compartment (MFTC) and extrusion area in JSN knees but not for noJSN knees. Also, the extrusion distance measured 4mm posterior to the central slice was not significantly correlated with MFTC cartilage loss. The strongest (negative) correlation between meniscus position and subregional femorotibial cartilage loss (r=−0.36) was observed for the external medial tibia. In contrast, no significant relationship was seen in the central tibia. No significant relationship was found in other tibial subregions, except for the anterior medial tibia, but only in JSN knees (r=−0.27). Correlation coefficients for the femoral subregions were generally smaller than those for tibial subregions, with only the internal medial weight-bearing femur attaining statistical significance (r =−0.26). Conclusions. The current results show that the relationship between meniscus extrusion and cartilage loss differs substantially between femorotibial subregions. The correlation was strongest for the external medial tibia, a region that is physiologically covered by the medial meniscus. It was less for other tibial and femoral subregions, including the central medial tibia, a region that exhibited similar rates of cartilage loss as the external subregion. The findings suggest that external tibia may be particularly vulnerable to cartilage tissue loss once the meniscus extrudes and the surface is “exposed” to direct, non-physiological, cartilage-cartilage contact

Anterior cruciate ligament (ACL) of four major knee ligaments is most crucial ligament to maintain normal knee kinematics. It is well know that ACL dysfunction causes secondary osteoarthritis of the knee. The influence of age on the biomechanical properties of the ACL was examined. The structural properties of 27 pairs of human cadaver knees without OA were evaluated. Specimens were equally divided into three groups of nine pairs each based on age: younger (22 to 35 years), middle (40 to 50 years), and older (60 to 97 years). Tensile tests of the femur-ACL-tibia complex were performed at 30 degrees of knee flexion with the ACL aligned vertically along the direction of applied tensile load. Structural properties of the femur-ACL-tibia complex, as represented by the linear stiffness, ultimate load, and energy absorbed, were found to decrease significantly with specimen age. On the other hand, little has been written about the arthritic ACL. This study was designed to evaluate the relationship among ROM, cross sections of the intercondylar notch and the macroscopic condition of ACL degeneration. Fifty osteoarthritic patients who underwent TKA as a result of severe osteoarthritis were randomly selected. Occupation rate of the osteophytes to the notch width were measured at the anterior 1/3, middle 1/3, and posterior 1/3 notche images obtained from preoperative tunnel view. ROM was measured preoperatively and under anesthesia. Macroscopic conditions of the ACL and PCL were classified into four types of Normal, Frayed, Partial rupture, and Absent. The macroscopic ACL conditions were Normal: 12 cases, Frayed: 15 cases, Partial rupture: 14 cases, and Absent: 9 cases. The macroscopic PCL conditions were Normal: 34 cases, Frayed: 9 cases, Partial rupture: 7 cases, and Absent: 0 case. Occupation rate of the osteophytes to the notch correlated to the preoperative varus deformity (p < 0.05). In terms of ACL, the occupation rate of the osteophytes to the notch were 22.9%, 28.8%, 46.0%, and 81.8% in Normal, Frayed, partial ruptured, and Absent, respectively. The patients with more than 40% occupation rate and less than 110 degree of knee flexion angle showed either partial rupture or absent of the ACL during the surgery. Those results correlated with the degree of OA deterioration. We conclude that occupation rate of the osteophytes to the notch poor preoperative ROM is a good predictor of evaluating the ACL degeneration in osteoarthritic knee. We also conclude that ACL dysfunction due to joint space narrowing accelerates the advancement of the knee OA

Background. Rotational acetabular osteotomy (RAO) is an effective treatment option for symptomatic acetabular dysplasia. However, excessive lateral and anterior correction during the periacetabular osteotomy may lead to femoroacetabular impingement. We used preoperative planning software for total hip arthroplasty to perform femoroacetabular impingement simulations before and after rotational acetabular osteotomies. Methods. We evaluated 11 hips in 11 patients with available computed tomography taken before and after RAO. All cases were female and mean age at the time of surgery was 35.9 years. All cases were early stage osteoarthritis without obvious osteophytes or joint space narrowing. Radiographic analysis included the center-edge (CE) angle, Sharp's acetabular angle, the acetabular roof angle, the acetabular head index (AHI), cross-over sign, and posterior wall sign. Acetabular anteversion was measured at every 5 mm slice level in the femoral head using preoperative and postoperative computed tomography. Impingement simulations were performed using the preoperative planning software ZedHip (LEXI, Tokyo, Japan). In brief, we created a three-dimensional model. The range of motion which causes bone-to-bone impingement was evaluated in flexion (flex), abduction (abd), external rotation in flex 0°, and internal rotation in flex 90°. The lesions caused by impingement were evaluated. Results. In the radiographic measurements, the CE angle, Sharp's angle, acetabular roof angle, and AHI all indicated improved postoperative acetabular coverage. The cross-over sign was recognized pre- and postoperatively in each case. Acetabular retroversion appeared in one case before RAO and in three cases after RAO. Preoperatively, there was a tendency to reduce the acetabular anteverison angle in the hips from distal levels to proximal. In contrast, there was no postoperative difference in the acetabular anteversion angle at any level. In our simulation study, bone-to-bone impingement occurred in flex (preoperative/postoperative, 137°/114°), abd (73°/54°), external rotation in flex 0°(34°/43°), and internal rotation in flex 90°(70°/36°). Impingement occurred within internal rotation 45°in flexion 90°in two preoperative and eight postoperative cases. The impingement lesions were anterosuperior of the acetabulum in all cases. Discussion. It is easy to make and assess an impingement simulation using preoperative planning software, and our data suggest the simulation was helpful in a clinical setting, though there were some remaining problems such as approximation of the femoral head center and differences in femur movement between the simulation and reality. In the postoperative simulation there was a tendency to reduce the range of motion in flex, abd, and internal rotation in flex 90°. There was a correlation between acetabular anteversion angle and flex. Since impingement occurred within internal rotation 45°in flexion 90°in eight postoperative simulations, we consider there is a strong potential for an increase in femoroacetabular impingement after RAO

The purpose of this study was to determine the motion pattern of the Acromio-Clavicular (AC) joint in a normal shoulder with the use of the new 4 Dimensional CT scan. From April 2010 till January 2011 fourteen healthy volunteers (4 female, 10 male)(mean age 42±11 years) with no previous history of shoulder complaints participated in this study. The 4D CT machine scans motion, allowing a 3D reconstruction of the shoulder joint and its movements. Patients were positioned supine with their arm elevated 90° in the sagittal plane. During the 7 seconds duration of the scan they adducted their arm at that level and then elevated their arm upwards resisted by the gantry for 4 seconds, in this way simulating the clinical Bell-van Riet test for AC pathology. In the transverse plane the mean AC joint space measured in the neutral position is 1.8±0.5 mm. While adducting the arm the AC joint narrows 0.0±0.4 mm (with a positive value being narrowing and a negative value widening). On resisted elevation the joint space is narrowed 0.2±0.6 mm. The mean antero-posterior (AP) translation in this same plane is 0.2±2.2 mm on adduction (with a positive value being posterior translation of the clavicle and a negative value anterior translation) and 0.4±2.9 mm on resisted elevation. The new 4D CT scan demonstrates that the AC joint in a normal shoulder mainly translates in an AP direction, rather than being narrowed or widened, when the arm is adducted (with or without resisted active elevation)

Atlanto-axial subluxation (AAS) presents with marked frequency among patients with instability in rheumatoid arthritis (RA) patients. This study investigated the morphology of the atlanto-occipital joint (AOJ) in AAS patients due to RA using computed tomography, and examined the relationship between its morphology and other radiographic results. Twenty-six consecutive patients with AAS due to RA treated by surgery were reviewed. In all patients, the AOJ was morphologically evaluated using sagittal reconstruction view on computed tomography before surgery. Moreover, the ADI value was investigated at the neutral position, and atlanto-axial angle (AAA) at the neutral and maximal flexion position in preoperative lateral cradiographs. The morphology of the AOJ was classified into three types as follows: a normal type which showed a maintenance of the joint space, a narrow type which showed a disappearance of the joint space and a fused type which showed the fusion of the AOJ. The pre-operative CT image of the AOJ demonstrated a normal type bilaterally in six cases (Group A). In 15 cases (Group B), CT image demonstrated narrowing on at least one side of the AOJ. In five cases (Group C), CT images demonstrated fusion on at least one side of the AOJ. The average ADI value at the flexion position was 10.7 mm in Group A, 11.7 mm in Group B, and 12.6 mm in Group C. There was no significant difference among those groups. The average ADI value at the neutral position before surgery was 2.8 mm in Group A, 5.9 mm in Group B, and 10.4 mm in Group C. There was no significant difference between Group A and B, and Group B and C; however, there was a significant difference between Group A and C (p < 0.004). The average AAA value was 25.3 degrees in Group A, 19.3 degrees in Group B and 3.4 degrees in Group C. There was no significant difference between Group A and B; however, there was a significant difference between Group A and C (p < 0.002), and Group B and C (p < 0.007). This study showed that fusion or ankylosis of the AOJ induced an enlargement of the ADI and anterior inclination of the atlas in the neutral position—despite the fact that normal findings of AOJ showed a slight displacement of the atlas to axis in RA patients showing AAS involvement