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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_4 | Pages 130 - 130
1 Apr 2019
Tamura K Takao M Hamada H Sakai T Sugano N
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Introduction. Most of patients with unilateral hip disease shows muscle volume atrophy of pelvis and thigh in the affected side because of pain and disuse, resulting in reduced muscle weakness and limping. However, it is unclear how the muscle atrophy correlated with muscle strength in the patient with hip disorders. A previous study have demonstrated that the volume of the gluteus medius correlated with the muscle strength by volumetric measurement using 3 dimensional computed tomography (3D-CT) data, however, muscles influence each other during motions and there is no reports focusing on the relationship between some major muscles of pelvis and thigh including gluteus maximus, gluteus medius, iliopsoas and quadriceps and muscle strength in several hip and knee motions. Therefore, the purpose of the present study is to evaluate the relationship between muscle volumetric atrophy of major muscles of pelvis and thigh and muscle strength in flexion, extension and abduction of hip joints and extension of knee joint before surgery in patients with unilateral hip disease. Material and Methods. The subjects were 38 patients with unilateral hip osteoarthritis, who underwent hip joint surgery. They all underwent preoperative computed tomography (CT) for preoperative planning. There were 6 males and 32 females with average age 59.5 years old. Before surgery, isometric muscle strength in hip flexion, hip extension, hip abduction and knee extension were measured using a hand held dynamometer (µTas F-1, ANIMA Japan). Major muscles including gluteus maximus, gluteus medius, iliopsoas and quadriceps were automatically extracted from the preoperative CT using convolutional neural networks (CNN) and were corrected manually by the experienced surgeon. The muscle volumetric atrophy ratio was defined as the ratio of muscle volume of the affected side to that of the unaffected side. The muscle weakness ratio was defined as the ratio of muscle strength of the affected side to that of the unaffected side. The correlation coefficient between the muscle atrophy ratio and the muscle weakness ratio of each muscle were calculated. Results. The average muscle atrophy ratio was 84.5% (63.5%–108.2%) in gluteus maximus, 86.6% (65.5%–112.1%) in gluteus medius, 81.0% (22.1%–130.8%) in psoas major, and 91.0% (63.8%–127.0%) in quadriceps. The average muscle strength ratio was 71.5% (0%–137.5%) in hip flexion, 88.1% (18.8%–169.6%) in hip abduction, 78.6% (21.9%–130.1%) in hip extension and 84.3% (13.1%–122.8%) in knee extension. The correlation coefficient between the muscle atrophy and the ratio of each muscle strength between the affected and unaffected side were shown in Table 1. Conclusion. In conclusion, the muscle atrophy of gluteus medius muscle, psoas major muscle and quadriceps muscle significantly correlated with the muscle weakness in hip flexion. The muscle atrophy of psoas major muscle and quadriceps muscle also significantly correlated with the muscle weakness in knee extension. There were no significant correlation between the muscle atrophy and the muscle weakness in hip extension and abduction


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_9 | Pages 59 - 59
1 May 2016
Mount L Su S Su E
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Introduction. Patients presenting with osteoarthritis as late sequelae following pediatric hip trauma have few options aside from standard Total Hip Replacement (THR). For younger more active patients, Hip Resurfacing Arthroplasty (HRA) can be offered as an alternative. HRA has been performed in the United States over the past decade and allows increased bone preservation, decreased hip dislocation rates versus THR, and potential to return to full activities. Patients presenting with end-stage hip arthritis as following prior pediatric trauma or disease often have altered hip morphology making HRA more complicated. Often Legg-Calve-Perthes (LCP) patients present with short, wide femoral necks, and femoral head distortion including coxa magna or coxa plana. There often can be acetabular dysplasia in conjunction with the proximal femoral abnormalities. Slipped Capital Femoral Epiphysis (SCFE) patients have an alteration of the femoral neck and head alignment, which can make reshaping the femoral head difficult. In particular, the femoral head is rotated medially and posteriorly, reducing the anterior and lateral offset. We present a cohort of 20 patients, with history of a childhood hip disorder (SCFE or LCP), who underwent HRA to treat end-stage arthritis. Fifty percent had prior pediatric surgical intervention at an average age of 11. Method. After Institutional Review Board approval, data was reviewed retrospectively on patients with pediatric hip diseases of SCFE and LCP who underwent HRA using the Birmingham Hip Resurfacing (BHR) by a single orthopaedic surgeon at a teaching institution. Harris Hip Scores (HHS), plain radiographs and blood metal ion levels were reviewed at routine intervals (12 months and annually thereafter). Those who had not returned for recent follow-up were contacted via telephone survey for a modified HHS. Results. Twenty patients had mean follow up of 2.8 years (range 1–7 years). Twelve had LCP and 8 SCFE. Median implant duration was 2.4 years. One-year metal ion testing revealed median chromium level of 2.3 ppb and median Cobalt level of 1.5 ppb. At one-year follow up, plain radiographs demonstrated all patient implants to be well-fixed, without radiolucent lines or osteolysis. Two patients at three and five-year follow-up exhibited heterotopic ossification. Mean HHS for LCP at 6 weeks post-operative was 88, and 98 at one year. Mean HHS for SCFE at 6 weeks post-operative was 77.5, and 98.6 at one year. LLD was significantly improved with an average pre-operative LLD of 12.6 mm and post op of 2.6 mm (p-value <0.001). At most recent follow-up, all retained their implants with overall average HHS of 98. Conclusion. At minimum of one-year following HRA, an increase in functional outcomes is found in patients who underwent HRA for osteoarthritis associated with LCP and SCFE with a mean HHS of 98. No increase was found in complications including femoral neck fracture or implant loosening despite technical challenges of the procedure related to proximal femoral morphologic abnormalities, or presence of acetabular dysplasia [Fig 1]


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_4 | Pages 146 - 146
1 Jan 2016
Yoshii H Oinuma K Tamaki T Jonishi K Miura Y Shiratsuchi H
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Purpose. Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire (JHEQ) is subjective assessment of coxarthropathy and reflects the satisfaction level of the patient. Recently, the use of JHEQ as a postoperative assessment of total hip arthroplasty (THA) has become widespread. The aim of this study was to investigate the clinical outcomes of bilateral simultaneous THA through the direct anterior approach (DAA) using JHEQ. Methods. This study included 34 patients (41 hips) who were treated with first THA at our hospital from January to March 2013 and were available for evaluation of clinical outcomes 1 year after surgery. Of these, 7 (2 males and 5 females; mean age, 54.7 years) underwent bilateral simultaneous THA (group B), and 27 (2 males and 25 females; mean age, 64.2 years) underwent unilateral THA (group U). Thirty patients were preoperatively diagnosed with hip osteoarthritis, and 4 were diagnosed with avascular necrosis of the femoral head. All patients were treated through DAA in a supine position under general anaesthesia. Items for evaluation included clinical outcomes, Japanese Orthopaedic Association Hip score (JOA score) and JHEQ. Results. Average operative time per hip was 45.9 min (range, 34–79 min) in group B and 44.2 min (range, 32–71 min) in group U. Average blood loss was 221.4 g (range, 40–1040 g) in group B and 386.9 g (range, 70–1300 g) in group U. No major complications such as dislocation, bone fracture, nerve palsy or venous thromboembolism were observed. The average JOA score improved from 45.1 preoperatively to 93.7 at 1 year postoperatively in group B and from 47.2 preoperatively to 92.3 at 1 year postoperatively in group U. Average total JHEQ (pain/motion/mental status) improved from 21 (preoperative, 12/2/7) to 75 (1 year postoperatively, 27/23/25) in group B and from 26 (preoperative, 10/7/10) to 69 (1 year postoperatively, 25/21/24) in group U. Discussion. Bilateral simultaneous THA was proactively performed when indicated at our hospital. In the present study, we observed greater improvement in JHEQ in patients treated with bilateral simultaneous THA than in those treated with unilateral THA. These findings suggest that bilateral simultaneous THA results in greater postoperative satisfaction of the patient


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_5 | Pages 77 - 77
1 Apr 2018
Su E Khan I Gaillard M Gross T
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INTRODUCTION

Childhood diseases involving the proximal femoral epiphysis often cause abnormalities that can lead to end-stage arthritis at a relatively young age and the need for total hip arthroplasty (THA). The young age of these patients makes hip resurfacing arthroplasty (HRA) an alternative and favorable option due to the ability to preserve femoral bone.

Patients presenting with end-stage hip arthritis as sequelae of childhood diseases such as Legg-Calves-Perthes (LCP) and slipped capital femoral epiphysis (SCFE) pose altered femoral anatomy, making HRA more technically complicated. LCP patients can result in coxa magna, coxa plana and coxa breva causing altered femoral head-to-neck ratio. There can also be acetabular dysplasia along with the proximal femoral abnormalities. SCFE patients have altered femoral head alignment. In particular, the femoral head is rotated medially and posteriorly, reducing the anterior and lateral offset. Additionally, many of these patients have retained hardware, making resurfacing more complicated.

We report findings of a cohort of patients, with history of either LCP or SCPE who underwent HRA to treat end-stage arthritis.

METHODS

Data was retrospectively collected for patients who had HRA for hip arthritis as a result of either LCP (n=67) or SCFE (n=21) between 2004 and 2014 performed by two surgeons. Demographic information, clinical examination and improvement was collected pre and postoperatively. Improvement was determined using Harris Hip Scores (HHS) and UCLA activity scores. Anteroposterior radiographs were measured pre and postoperatively to determine leg length discrepancy. Radiographs were inspected postoperatively for radiolucent lines, implant loosening and osteolysis. Kaplan-Meier survivorship for freedom from reoperation for any reason was calculated. Paired student t-tests were used to compare groups.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_8 | Pages 6 - 6
1 Aug 2020
Wilson I Gascoyne T Turgeon T Burnell C
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Total hip arthroplasty (THA) is one of the most successful and commonly performed surgical interventions worldwide. Based on registry data, at one-year post THA, implant survivorship is nearly 100% and patient satisfaction is 90%. A novel, porous coated acetabular implant was introduced in Europe and Australia in 2007. Several years after its introduction, warnings were issued for the system when used with metal-on-metal bearings due to adverse local tissue reaction, with one study reporting a 24% failure rate (Dramis et al. 2014). A subsequent 2018 study by Teoh et al. showed that the acetabular system had a survival rate of 98.9% at five years when used with conventional polyethylene or ceramic bearing surfaces. The current study was conducted to determine the safety and effectiveness of the acetabular system using standard highly-crosslinked polyethylene (XLPE) and ceramic liners at five-year follow-up. Our hypothesis was that the acetabular system would exhibit survivorship comparable to other acetabular components on the market at five-year follow-up.

A prospective, non-randomized study was conducted from February 2009 to June 2017 at eight sites in Canada and the USA. One hundred fifty-five hips were enrolled and 148 hips analyzed after THA indicated for degenerative arthritis. At five-year follow-up, 103 subjects remained for final analysis. All patients received a zero, three, or multi-hole R3 acetabular shell with Stiktite porous coating (Smith & Nephew, Inc., Memphis, TN, USA). Standard THA surgical techniques were employed, with surgical approach and either of a XLPE or ceramic bearing surface chosen at the discretion of the surgeon. The primary outcome was revision at five-years post-op with secondary outcomes including the Harris Hip Score (HHS), Hip Disability and Osteoarthritis Outcome Score (HOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), radiographic analysis, and post-operative adverse events. Data and outcomes were analyzed using summary statistics with 95% confidence intervals, t-tests, and Wilcoxon Rank tests.

At five-year follow-up the overall success rate was 97.14% (95% CI: 91.88–100). When analyzed by liner type, the success rate was 96.81% (95% CI: 90.96–99.34) for polyethylene (n=94) and 100% (95% CI: 71.51–100) for ceramic (n=11), with no significant difference between either liner type (p=1). There were three revisions during the study (1.9%), two for femoral stem revision post fracture, and one for deep infection. The HHS (51.36 pre-op, 94.50 five-year), all 5 HOOS sub-scales, and WOMAC (40.9 pre-op, 89.13 five-year) scores all significantly improved (p < 0 .001) over baseline scores at all follow-up points. One (0.7%) subject met the criteria for radiographic failure at one-year post-op but did not require revision. Six (1.8%) of the reported adverse events were considered related to the study device, including four cases of squeaking, one bursitis, and one femur fracture.

Results from this five-year, multicenter, prospective study indicate good survivorship for this novel, porous coated acetabular system. The overall survivorship of 97.14% at five-year follow-up is comparable to that reported for similar acetabular components and aligns with previous analyses (Teoh et al. 2018).


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 180 - 180
1 Sep 2012
Shore BJ Howard JJ Selber P Graham H
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Purpose

The incidence of hip displacement in children with cerebral palsy is approximately 30% in large population based studies. The purpose of this study was to report the long-term effect of hip surgery on the incidence of hip displacement using a newly validated Cerebral Palsy (CP) hip classification.

Method

Retrospectively, a sub-group of 100 children who underwent surgery for hip displacement were identified from a large-population based cohort of children born with CP between January 1990 and December 1992. These children were followed to skeletal maturity and closure of their tri-radiate cartilage. All patients returned at maturity for clinical and radiographic examination, while caregivers completed the disease specific quality of life assessments. Patients were grouped according to motor disorder, topographical distribution and GMFCS. Radiographs were independently graded according to CP hip classification scheme to ensure reliability. Surgical Failures were defined as CP Grade > IV.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_3 | Pages 23 - 23
1 Mar 2021
Kelley S Maddock C Bradley C Gargan M Safir O
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The use of total hip arthroplasty in adolescents for end-stage degenerative hip disease is controversial with few reported outcomes in the literature. The purpose of the study was to report the outcomes of total hip arthroplasty in a cohort of adolescents managed by a multidisciplinary team of paediatric and adult orthopaedic surgeons from a single centre. A multidisciplinary clinic consisting of paediatric and adult hip surgeons was established in 2013 to identify, treat and prospectively follow adolescents who would potentially beneift from a total hip arthoplasty. To date 29 consecutive adolescent patients (20 female, 9 male, 32 hips) with end stage degenerative hip disease have undergone cementless primary total hip arthroplasty. Mean age at decision to treat was 15.7 years (age 11.4–18.5). Ten different underlying paediatric specific pathologies were documented including DDH, cerebral palsy, JIA, skeletal dysplasias, SCFE and idiopathic chondrolysis. Three patients had bilateral staged procedures. Clinical baseline and outcomes were measured using Oxford Hip Score (OHS), WOMAC score and ASKp scores. Radiographic follow-up was conducted at 6 weeks, 6 months and yearly thereafter. Post-operative complications were recorded. Twenty-five hips were eligible for minimum 2-year follow-up scoring at a mean 2.7 years (2.0–3.6 years). No intraoperative complications occurred. One case of recalcitrant postoperative psoas tendonitis occured. OHS improved from 25 (7–43) to 41 (23–48). WOMAC improved from 48 (12–8) to 12 (1–44), and ASKp improved from 78% (33–98%) to 93% (73–100%). Radiographic review revealed acceptable alignment of all components with no signs of loosening or wear. No revision of components was required. One patient died at 6 months post op from an unrelated condition. The early term results of total hip arthroplasty in adolescents from our multidisciplinary program are encouraging. Improvements in quality of life to normal values were seen as were hip scores consistent with satisfactory joint function. Depite the range of complex and varied causes of arthritis seen in this population the establishment of combined paediatric and adult orthopaedic surgical teams appears to be a successful model to manage end-stage degenerative hip disease in adolescents


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_12 | Pages 24 - 24
1 Dec 2022
Tyrpenou E Megaloikonomos P Epure LM Huk OL Zukor DJ Antoniou J
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Simultaneous bilateral total hip arthroplasty (THA) in patients with bilateral hip osteoarthritis is gradually becoming attractive, as it requires a single anesthesia and hospitalization. However, there are concerns about the potential complications following this surgical option. The purpose of this study is to compare the short-term major and minor complications and assess the readmission rate, between patients treated with same-day bilateral THA and those with staged procedures within a year. We retrospectively reviewed the charts of all patients with bilateral hip osteoarthritis that underwent simultaneous or staged (within a year) bilateral total THA in our institution, between 2016-2020. Preoperative patient variables between the two groups were compared using the 2-sample t-test for continuous variables, the Fisher's exact test for binary variables, or the chi-square test for multiple categorical variables. Similarly, differences in the 30-day major and minor complications and readmission rates were assessed. A logistic regression model was also developed to identify potential risk factors. A total of 160 patients (mean age: 64.3 years, SD: ±11.7) that underwent bilateral THA was identified. Seventy-nine patients were treated with simultaneous and eighty-one patients with staged procedures. There were no differences in terms of preoperative laboratory values, gender, age, Body Mass Index (BMI), or American Society of Anesthesiologists Scores (ASA) (p>0.05) between the two groups. Patients in the simultaneous group were more likely to receive general anesthesia (43% vs 9.9%, p0.05). After controlling for potential confounders, the multivariable logistic regression analysis showed similar odds of having a major (odds ratio 0.29, 95% confidence interval [0.30-2.88], p=0.29) or minor (odds ratio 1.714, 95% confidence interval [0.66-4.46], p=0.27) complication after simultaneous compared to staged bilateral THA. No differences in emergency department visits or readmission for reasons related to the procedure were recorded (p>0.05). This study shows that similar complication and readmission rates are expected after simultaneous and staged THAs. Simultaneous bilateral THA is a safe and effective procedure, that should be sought actively and counselled by surgeons, for patients that present with radiologic and clinical bilateral hip disease


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_8 | Pages 73 - 73
1 May 2019
Lee G
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Arthrosis of the hip joint can be a significant source of pain and dysfunction. While hip replacement surgery has emerged as the gold standard for the treatment of end stage coxarthrosis, there are several non-arthroplasty management options that can help patients with mild and moderate hip arthritis. Therefore, the purpose of this paper is to review early prophylactic interventions that may help defer or avoid hip arthroplasty. Nonoperative management for the symptomatic hip involves minimizing joint inflammation and maximizing joint mobility through intra-articular joint injections and exercise therapy. While weight loss, activity modifications, and low impact exercises is generally recommended for patients with arthritis, the effects of these modalities on joint strength and mobility are highly variable. Intra-articular steroid injections tended to offer reliable short-term pain relief (3–4 weeks) but provided unreliable long-term efficacy. Additionally, injections of hyaluronic acid do not appear to provide improved pain relief compared to other modalities. Finally, platelet rich plasma injections do not perform better than HA injections for patients with moderate hip joint arthrosis. Primary hip joint arthrosis is rare, and therefore treatment such as peri-acetabular osteotomies, surgical dislocations, and hip arthroscopy and related procedures are aimed to minimise symptoms but potentially aim to alter the natural history of hip diseases. The state of the articular cartilage at the time of surgery is critical to the success or failure of any joint preservation procedures. Lech et al. reported in a series of dysplastic patients undergoing periacetabular osteotomies that one third of hips survived 30 years without progression of arthritis or conversion to THA. Similarly, surgical dislocation of the hip, while effective for treatment of femoroacetabular impingement, carries a high re-operation rate at 7 years follow up. Finally, as the prevalence of hip arthroscopic procedures continues to rise, it is important to recognise that failure to address the underlying structural pathologies can lead to failure and rapid joint destruction. In summary, several treatment modalities are available for the management of hip pain and dysfunction in patients with a preserved joint space. While joint preservation procedures can help improve pain and function, they rarely alter the natural history of hip disease. The status of the articular cartilage at the time of surgery is the most important predictor of treatment success or failure


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 56 - 56
1 Mar 2017
Uemura K Takao M Otake Y Koyama K Yokota F Hamada H Sakai T Sato Y Sugano N
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Background. Cup anteversion and inclination are important to avoid implant impingement and dislocation in total hip arthroplasty (THA). However, it is well known that functional cup anteversion and cup inclination also change as the pelvic sagittal inclination (PSI) changes, and many reports have been made to investigate the PSI in supine and standing positions. However, the maximum numbers of subjects studied are around 150 due to the requirement of considerable manual input in measuring the PSIs. Therefore, PSI in supine and standing positions were measured fully automatically with a computational method in a large cohort, and the factors which relate to the PSI change from supine to standing were analyzed in this study. Methods. A total of 422 patients who underwent THA from 2011 to 2015 were the subjects of this study. There were 83 patients with primary OA, 274 patients with DDH derived secondary OA (DDH-OA), 48 patients with osteonecrosis, and 17 patients with rapidly destructive coxopathy (RDC). The median age of the patient was 61 (range; 15–87). Preoperative PSI in supine and standing positions were measured and the number of cases in which PSI changed more than 10° posteriorly were calculated. PSI in supine was measured as the angle between the anterior pelvic plane (APP) and the horizontal line of the body on the sagittal plane of APP, and PSI in standing was measured as the angle between the APP and the line perpendicular to the horizontal surface on the sagittal plane of APP (Fig. 1). The value was set positive if the pelvis was tilted anteriorly and was set negative if the pelvis tilted posteriorly. Type of hip disease, sex, and age were analyzed with multiple logistic regression analysis if they were related to PSI change of more than 10°. For accuracy verification, PSI in supine and standing were measured manually with the previous manual method in 100 cases and were compared with the automated system used in this study. Results. The median PSI in the supine position was 5.1° (interquartile range [IQR]: 0.4 to 9.4°), and the median PSI in the standing position was −1.3° (IQR: −6.5 to 4.2°). There were 79 cases (19%) in which the PSI changed more than 10° posteriorly from supine to standing with a maximum change of 36.9° (Fig. 2). In the analysis of the factors, type of hip disease (p = 0.015) and age (p = 0.006, Odds Ratio [OR] = 1.035) were the significant factors. The OR of primary OA (p = 0.005, OR: 2.365) and RDC (p = 0.03, OR: 3.146) were significantly higher than DDH-OA. In accuracy verification, the automated PSI measurement showed ICC of 0.992 (95% CI: 0.988 to 0.955) for supine measurement and 0.978 (95% CI: 0.952 to 0.988) for standing measurement. Conclusions. PSI changed more than 10° posteriorly from supine to standing in 19% of the cases. Age and diagnosis of primary OA and RDC were related to having their pelvis recline more than 10° posteriorly. For any figures or tables, please contact authors directly (see Info & Metrics tab above).


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_10 | Pages 31 - 31
1 Jun 2018
Rosenberg A
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Down syndrome (DS), is a genetic disorder caused by a third copy of the 21st chromosome (Trisomy 21), featuring typical facial characteristics, growth delays and varying degrees of intellectual disability. Some degree of immune deficiency is variably present. Multiple orthopaedic conditions are associated, including stunted growth (90%), ligamentous laxity (90%), low muscle tone (80%), hand and foot deformities (60%), hip instability (30%), and spinal abnormalities including atlanto-axial instability (20%) and scoliosis. Hip disease severity varies and follows a variable time course. Rarely a child presents with DDH, but during the first 2 years the hips are characteristically stable but hypermobile with well-formed acetabulae. Spontaneous subluxation or dislocation after 2 presents with painless clicking, limping or giving way. Acute dislocation is associated with moderate pain, increased limp and reduced activity following minor trauma. Hips are reducible under anesthesia, but recurrence is common. Eventually concentric reduction becomes rarer and radiographic dysplasia develops. Pathology includes: a thin, weak fibrous capsule, moderate to severe femoral neck anteversion and a posterior superior acetabular rim deficiency. A number of femoral and acetabular osteotomies have been reported to treat the dysplasia, with acetabular redirection appearing to be most successful. However, surgery can be associated with a relatively high infection rate (20%). Additionally, symptomatic femoral head avascular necrosis can occur as a result of slipped capital femoral epiphysis. Untreated dysplasia patients can walk with a limp and little pain into the early twenties even with fixed dislocation. Pain and decreasing hip function is commonly seen as the patient enters adult life. Occasionally the hip instability begins after skeletal maturity. Total hip arthroplasty (THA) is the standard treatment when sufficient symptoms have developed. The clinical outcomes of 42 THAs in patients with Down syndrome were all successfully treated with standard components. The use of constrained liners to treat intra-operative instability occurred in eight hips and survival rates were noted between 81% and 100% at a mean follow-up of 105 months (6 – 292 months). A more recent study of 241 patients with Down syndrome and a matched 723-patient cohort from the Nationwide Inpatient Sample compared the incidence of peri-operative medical and surgical complications in those who underwent THA. Compared to matched controls, Down syndrome patients had an increased risk of complications: peri-operative (OR, 4.33; P<.001), medical (UTI & Pneumonia OR, 4.59; P<.001) and surgical (bleeding OR, 3.51; P<.001), Mean LOS was 26% longer (P<.001). While these patients can be challenging to treat, excellent surgical technique and selective use of acetabular constraint can reliably provide patients with excellent pain-relief and improved function. Pre-operative education of all clinical decision makers should also reinforce the increased risk of medical and surgical complications (wound hemorrhage), and lengths of stay compared to the general population


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 346 - 346
1 Dec 2013
Hedlund H Fellander-Tsai L
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Background:. Hip arthroplasty is very successful in order to alleviate pain and improve health-related quality of life. Health-care costs are constantly growing and the burden of patients with hip disease has increased dramatically. Careful consideration of the patients'need and expectations include not only the proper indication for surgery but also choice of method. Hip resurfacing (HRA) has been popularized during the last decade, being bone conservative, capable to restore the anatomical hip center and lower the risk of dislocation. Some HRA-designs have proven good long-term survival rate while others have shown an unacceptable high amount of loosening and been recalled. Yet, for a selected group of patients HRA may be advantageous to THA regarding health-related quality of life. A fundamental prerequisite understanding today's and tomorrow's request on hip arthroplasty is to measure outcomes from patients' perspectives. In this pilot study we compared the patient-reported outcome measures after hip resurfacing with THA using validated general and hip disease specific instruments. Methods:. A questionnaire was sent to 108 randomly selected patients (72% male) of a cohort of 259 patients (Charnley A+B) who had had uni- or bilateral (two stages) HRA for a period of at least six months. Maximal follow-up time was 7 years. Mean age was 50.2 years (males) and 46.2 years (females) respectively. Patients were reporting EQ-5D and self assessed health-quality (0–100%). In addition, a minor group randomly selected, reported their activity that was graded according to UCLA-activity score. As preoperative EQ-5D baseline, a matched group of 40 patients from the hospital's database scheduled for HRA served. Results:. 92 of 108 questionnaires with EQ-5D and self assessed health quality were complete. The mean postoperative EQ-5D was 0.89 (0.30 preoperative) and self assessed health quality being 59.3% (15–100) preoperatively was 80.2% (40–100) postoperatively. UCLA- activity score was 7.2 (4–9) postoperative. Of the whole group of 259 patients, three patients suffered from nerve palsy (two transient), two early cupmigrations (revised), one psoas-impingement and one AVN with cervical fracture (both revised), one deep infection, one ALTR and one dislocation (high-energy trauma). Conclusion:. Traditional outcome measures often fail to describe outcome from the patients' perspectives. This pilot study, with its limitations, shows that patients' health-related quality of life, as measured with EQ-5D after HRA is comparable to or better than that of THA. Patients with HRA in general seem to reach high activity level. However, adverse reactions to metal debris are escalating and with HRA compared to proven THA-designs the risk of complications, e.g., early loosening, especially in females, is higher. For men, no significant difference in survival rate is reported for HRA compared to THA. Yet, HRA should be considered in subgroups of patients (younger, active men), in order to gain high patient satisfaction


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_5 | Pages 32 - 32
1 Apr 2018
Van Der Straeten C Abdulhussein D Brevadt MJ Cobb J
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Background. Hip resurfacing arthroplasty (HRA) and total hip arthroplasty (THA) are treatments of end-stage hip disease. Gait analysis studies comparing HRA and THA have demonstrated that HRA results in a more normal gait than THA. The reasons may include the larger, more anatomic head diameter or the preservation of the neck of the femur with restoration of the anatomical position of the hip centre and normal proprioception. This study investigated (1) whether femoral head size diameter affects gait; (2) whether gait still differs between THA and HRA patients even with comparable head diameters. Methods. We retrospectively analysed the gait of 33 controls and 50 patients with a unilateral hip replacement, operated by the same surgeon. Follow-up ranged from 9–68 months. In 27 hips a small femoral head size was used (≤ 36mm); in 23 hips a large head size (>36mm). The small size group consisted of 11 long femoral stem THA and 16 short-stem THA and the large group of 5 long-stem THA, 8 short-stem THA and 10 HRA patients. There were 14 females/19 males in the control group; 22 females/5 males in the small size group; 13 females/10 males in the large size group. Results. (1) We found a significant difference in the step-length between the small head size group and the controls (p<0.01) at speeds ranging from 4.0 to 5.5 km/h but no difference between the larger head size and the controls. There was no significant difference in maximum speed, weight acceptance, push-off, mid-stance, impulse and cadence between the groups. (2) Analysis between THA and HRA in the large head size group revealed that there was a significant difference in the maximum speed (p=0.021) between the long-stem THA (6.338 km/h± 1.542) and HRA (7.756km/h± 0.7604) patients. At 5.5 km/h there was a significantly better weight acceptance (p=0.009) and mid-stance (p=0.041) of the HRA compared to short-stems. Impulse was significantly higher for HRA compared to long-stem THA (p<0.05) at all speeds ranging 4 to 5.5 km/h. (3) Males (7.1972 km/h ± .9700) had significantly higher maximum speeds compared to females (6.6524km/h± 1.019) (p=0.017) and lower gait impulse (p<0.01) at speeds ranging from 4 to 5.5km/h. (4) There was no significant difference in the Oxford Hip Score (OHS) and EQ-5D of patients in the small compared to the large head size group. Conclusions. Gait analysis demonstrated a significant difference in step length between THA patients with head size ≤ 36mm and normal controls. There was no difference in step length between normal controls and THA patients with larger head sizes. Compared to larger head size THA, the HRA still revealed higher maximum speeds and better weight acceptance. Males had significantly higher maximum speeds compared to females (controls and hip replacement patients). We could not demonstrate a correlation between better gait and Oxford scores or EQ-5D scores but these scores are known to have a ceiling effect. In a former study, better gait parameters such as longer step length and higher maximum speed have been associated with higher patient satisfaction


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 4 - 4
1 Mar 2017
Sidhu G Kaur H
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Introduction & aims. Total hip replacement is an excellent treatment option for people with late stage degenerative hip disease. In addition to marked reduction in pain and improvement in sleep, most people regain range of motion, physical ability and quality of life. This study aimed at the functional outcomes of large diameter heads in THR patients. Method. This study is an analysis of a cohort of patients undergoing total hip replacement performed at our hospital from November 2011 to July 2013. A total of 70 hips, 40 males and 30 females, were operated upon with large diameter femoral heads. The mean age was 50.38 years (range 40–59 years). In our cohort, 32 patients had AVN of femur head, 19 had post traumatic secondary degeneration, 10 had RA, 6 had AS and 3 patients had OA of hip. The follow-up data included local complications, Harris Hip Score, medical complications, readmission, activity status and use of a walking aid. Results. Harris hip score at final follow up was, 33 cases had excellent, 26 cases had good result. None of the patient had fair or poor result. Two cases of superficial infection were observed. One case of dislocation was observed in post operative period which was reduced under GA and patient was given abduction brace. The mean follow up was 16.31 months ranging from 6 to 32 months. During the follow up, we had mortality of two patients. One died at 14 months due to myocardial infarction and the cause of other died due to CVA at 10 months follow up. Conclusions. Lower dislocation rate and better range of motion in majority of cases reinforces the advantage of large diameter head in THR in young and active patients. For any figures or tables, please contact authors directly (see Info & Metrics tab above).


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_22 | Pages 28 - 28
1 Dec 2016
Parvizi J
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There are a number of progressive conditions that afflict the hip and result in degenerative arthritis. Along the path of progression of the disease and prior to the development of arthritis, some of these conditions may be treatable by joint preservation procedures. Periacetabular osteotomy for developmental dysplasia of the hip (DDH), femoroacetabular osteoplasty for femoroacetabular impingement (FAI), and a variety of surgical procedures for management of early osteonecrosis of the femoral head are some examples of joint preservation of the hip. DDH is characterised by abnormal development of the acetabulum and the proximal femur that leads to suboptimal contact of the articular surfaces and the resultant increase in joint reaction forces. FAI is a condition characterised by an abnormal contact between the femoral neck and the acetabular rim. FAI is believed to exist when a triad of signs (abnormal alpha angle, labral tear, and chondral lesion) can be identified. The question that remains is whether joint preservation procedures are able to avert the need for arthroplasty or just an intervention along the natural path of progression of the hip disease. There is an interesting study that followed 628 infants born in a Navajo reservation, including 8 infants with severe dysplasia, for 35 years. None of the children with DDH had surgical treatment and all had developed severe arthritis in the interim. The latter study and a few other natural history studies have shown that the lack of administration of surgical treatment to patients with symptomatic DDH results in accelerated arthritis. The situation is not so clear with FAI. Some believe that FAI is a pre-arthritic condition and surgical treatment is only effective in addressing the symptoms and does not delay or defer an arthroplasty. While others believe that restoration of the normal mechanical environment to the hip of FAI patients, by removing the abnormal contact and repair of the labrum, is likely to change the natural history of the disease and at minimum delay the need for an arthroplasty. There is a need for natural history studies or case series to settle the latter controversy


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_1 | Pages 32 - 32
1 Feb 2015
McCarthy J
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There is an increased incidence of dislocation, dysplasia, slipped epiphysis, Perthes’ disease, and avascular necrosis leading to degenerative arthritis which occurs in up to 28% of Down's syndrome patients. As the life expectancy for patients with Down's syndrome has increased, so has the presence of hip disease. Hip replacement has been shown to have good results in this population. Special considerations include a high risk of postoperative dislocation and leg length inequality which often require large head THR or dual mobility type reconstruction to reduce these risks. Numerous spine deformities including scoliosis and C1-2 subluxation need to be taken into account-anesthesia consult


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 42 - 42
1 Jan 2016
Mitsui H Iguchi H Nozaki M Watanabe N Goto H Nagaya Y Kobayashi M Otsuka T
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Objective. This study shows the radiographic results of total hip arthroplasty (THA) using the Revelation hip system. ®. for hip joint disease. Methods. We performed THA for hip disease using the Revelation Hip System. ®. From July 2007 to May 2009, 30cases (35 hips) were available for this study. Radiographic evaluation was performed at the last follow-up. Evaluation items included the presence or absence of subsidence, spot welds, demarcation line, cortical hypertrophy and stress shielding. The stem was designed to be implanted without cement and to be combined to the femur bone at the proximal portion to avoid stress shielding. Zone of Gruen zone 1 was divided into 1A or 1B, above and below the outermost tip of the lateral flare of the stem. Results. In total, 35 hips had spot welds at zones 1B and 7, and many hips had demarcation lines in zone 4 or 5, but not in zones 1B or 7. Cortical hypertrophy was detected in 6 cases in zone 3, the lateral edge of the stem. Stress shielding was first degree or second degree in 29 hips; however, no cases were identified with more than third-degree stress shielding. Discussion. At the proximal portion of the stem, spot welds were detected but demarcation lines were not, suggesting that bone ingrowth to the stem and combination of the stem and femur may have been completed in this area. Loading at the medial proximal end may not have occurred with a collarless cementless stem. First-degree stress shielding was thus considered a natural phenomenon that should not be seen as usual stress shielding. Cortical hypertrophy was detected in 17.1% of hips. Although no complaints such as thigh pain were identified, Revelation microMax. ®. , in which the unnecessary distal portion of the stem was shortened, was designed to address this problem


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 148 - 148
1 Feb 2017
Groves D Fisher J Williams S
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Introduction. Geometric variations of the hip joint can give rise to abnormal joint loading causing increased stress on the articular cartilage, which may ultimately lead to degenerative joint disease. In-vitro simulations of total hip replacements (THRs) have been widely reported in the literature, however, investigations exploring the tribology of two contacting cartilage surfaces, and cartilage against metal surfaces using complete hip joint models are less well reported. The aim of this study was to develop an in-vitro simulation system for investigating and comparing the tribology of complete natural hip joints and hemiarthroplasties with THR tribology. The simulation system was used to assess natural porcine hip joints and porcine hemiarthroplasty hip joints. Mean friction factor was used as the primary outcome measure to make between-group comparisons, and comparisons with previously published tribological studies. Method. In-vitro simulations were conducted on harvested porcine tissue. A method was developed enabling natural acetabula to be orientated with varying angles of version and inclination, and natural femoral heads to be potted centrally with different orientations in all three planes. Acetabula were potted with 45° of inclination and in the complete joint studies, natural femoral heads were anatomically matched and aligned (n=5). Hemiarthroplasty studies (n=5) were conducted using cobalt chrome (CoCr) heads mounted on a spigot (Figure 1), size-matched to the natural head. Natural tissue was fixed using PMMA (polymethyl methacrylate) bone cement. A pendulum friction simulator (Simulator Solutions, UK), with a dynamic loading regime of 25–800N, ± 15° flexion-extension (FE) at 1 Hertz was used. The lubricant was a 25% (v/v) bovine serum. Axial loading and motion was applied through the femoral head and frictional torque was measured using a piezoelectric transducer, from which the friction factor was calculated. Results. The correct anatomical orientation and positioning was achieved enabling in-vitro simulation testing to be conducted on hemiarthroplasty and complete hip joint samples for two-hours. Mean friction increased rapidly followed by a continued gradual increase to ≈0.03 ± 0.00 in the complete joints, with the hemiarthroplasty group plateauing at ≈0.05 ± 0.01 (Figure 2). Mean friction factor was significantly lower (t-test; p < 0.05) in the complete natural joint group. Discussion. An in-vitro simulation system for the natural hip joint with controlled orientation of the femur and acetabulum was successfully developed and used to measure friction in complete porcine hip joints and porcine hip hemiarthroplasties. A non-linear increase in friction indicative of biphasic lubrication was observed in both groups with slower exudation of fluid from the complete joints compared to the hemiarthroplasties, inferring a quicker move towards solid-phase lubrication. Higher friction in the hemiarthroplasties, which was similar to that measured in-vitro in metal-on-polyethylene THRs, was most likely due to variable clearances between the non-conforming spherical metal head and aspherical acetabulum, causing poorer congruity and distribution of the load. This could in time lead to abrasive wear and cartilage degradation. This methodology could have an important role when investigating associations between hip geometric variations, interventions for hip disease/pathology, and risk factors for cartilage degeneration


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 76 - 76
1 Feb 2017
Cobb J Wiik A Brevadt MJ Auvinet E Van Der Straeten C
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Intro. Across much of medicine, activity levels predict life expectancy, with low levels of activity being associated with increased mortality, and higher levels of activity being associated with longer healthier lives. Resurfacing is a technically demanding procedure that has suffered significant fallout from the failure of a couple of poorly performing designs. However strong evidence associates resurfacing with improved life expectancy in both the short and longer term following surgery. We wondered if there was any relationship between the function of hips following surgery and the extent of that surgery. Could a longer stem inside the femur be the reason for a slightly reduced step length? We proposed the nul hypothesis that there was no clinically relevant difference between stem length and gait. Method. After informed consent each subject was allowed a 5 minute acclimatisation period at 4km/hr on the instrumented treadmill (Kistler Gaitway, Amherst, NY). Their gait performance on an increasing incline at 5, 10 and 15%. At all 0.5km incremental intervals of speed, the vertical component of the ground reaction forces, center of pressure and temporal measurements were collected for both limbs with a sampling frequency of 100Hz over 10sec. They were also asked to log onto our JointPRO website and report their function using Oxford, EQ5D, and Imperial scores. Owing to current restrictions in indications, the patient groups selected were not comparable. However, from our database of over 800 patients who have been through the gait lab. 82 subjects were tested from 2 diagnostic groups (29 conventional THR, 27 hip resurfacing) and compared with a slightly younger group of 26 healthy controls. Patients were excluded if less than 12 months postop, or with any other documented joint disease or medical comorbidities which might affect gait performance. Body weight scaling was also applied to the outputted mechanical data to correct for mass differences. All variables for each subject group were compared to each other using an analysis of variance (ANOVA) with Tukey post hoc test with significance set at α=0.05. Results. The experimental groups were reasonably matched for sex, height and BMI, although the controls were rather younger, and the hip replacements rather older (young hip resurfacings were excluded for lack of good controls). Any differences did not reach significance. Oxford hip scores and EQ5D were almost identical for the two experimental groups. The THR group walked 10% slower than control (1.8 (±0.2)m/sec vs 2.0 (±0.1)m/sec). while the HRA group walked 5% faster (2.1(±0.2)m/sec). The difference between THR and control was significant (p<0.05). (See Figure 1). Discussion. This data records a 15% difference in top walking speed between THR and HRA, far exceeding the 5% threshold of clinical relevance. We therefore consider this improved functional outcome to be clinically relevant, and report with increasing confidence that hip resurfacings is an effective intervention in the treatment of hip disease with clinically relevant superiority over THR, even in a group with an average age of 60


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 148 - 148
1 May 2016
Garcia-Rey E Garcia-Cimbrelo E
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Introduction. The use of screws is frequent for additional fixation, however, since some disadvantages have been reported a cup press-fit is desirable, although this can not always be obtained. Cup primary intraoperative fixation in uncemented total hip replacement (THR) depends on sex, acetabular shape, and surgical technique. We analyzed different factors related to primary bone fixation of five different designs in patients only diagnosed with osteoarthritis, excluding severe congenital hip disease and inflammatory arthritis, and their clinical and radiological outcome. Materials y Methods. 791 hips operated in our Institution between 2002 and 2012 were included for the analysis. All cases were operated with the same press-fit technique, and screws were used according to the pull-out test. Two screws were used if there was any movement after the mentioned manoeuvres. Acetabular and femoral radiological shapes were classified according to Dorr et al. We analyzed radiological postoperative cup position for acetabular abduction angle, the horizontal distance and the vertical distance. Cup anteversion was evaluated according to Widmer and the hip rotation centre according to Ranawat. Results. Screws were required in 155 hips (19.6%) and were more frequently used in women and patients with a type A acetabulum (p<0.001, p=0.021, respectively). There were no differences among the different cups evaluated. The need for screws was more frequent in hips with a smaller version of the cup and with a distance greater than 2 mm to the approximate femoral head centre from the centre of the prosthetic femoral head (p=0.022, 0.012, respectively). Adjusted multivariate analysis revealed that female patients (p<0.001, Odds Ratio (OR): 2.063; 95% Confidence Interval (CI) 1.409–3.020), cups with a smaller version (p=0.012, OR: 0.966, 95% CI 0.94–0.992), and a greater distance to the rotation hip center (p<0.005, OR: 1.695; 95% CI 1.173–2.450) had a higher risk for screw use. No hips needed revision for aseptic loosening. Conclusions. Cup press-fit depends on gender and surgical technique in hips without significant acetabular abnormalities or inflammatory arthritis. Contemporary uncemented cups provide similar primary fixation and mid-term outcome