Aim. The treatment of fracture-related infections (FRI) focuses on obtaining fracture healing and eradicating infection to prevent osteomyelitis. Treatment guidelines include removal, exchange, or retention of the implants used according to the stability of the fracture and the time from the infection. Infection of a
Aim. To classify Fracture-related Infection (FRI) allowing comparison of clinical studies and to guide decision-making around the main surgical treatment concepts. Method. An international group of FRI experts met in Lisbon, June 2022 and proposed a new FRI classification. A core group met during the EBJIS Meeting in Graz, 2022 and on-line, to determine the preconditions, purpose, primary factors for inclusion, format and the detailed description of the elements of an FRI Classification. Results. Historically, FRI was classified by time from injury alone (early, delayed or late). Time produces pathophysiological changes which affect the bone, the soft-tissues and the patient general health, over a continuum. No definitive cut-off is therefore possible. Also, in several studies, time was not identified as an independent predictor of outcome. The most important primary factors were characteristics of the fracture (F), relevant systemic co-morbidities of the patient (R) and impairment of the soft-tissue envelope (I). These factors determine FRI severity, choice of treatment method and are predictors of outcome. For the
Treatment of segmental bone defects remains a major clinical problem, and innovative strategies are often necessary to successfully reconstruct large volumes of bone. When fractures occur, the resulting hematoma serves as a reservoir for growth factors and a space for cell infiltration, both crucial to the initiation of bone healing. Our previous studies have demonstrated very clear ultrastructural differences between
Introduction. We aimed to determine whether there are differences in patient-reported quality of life (QoL) outcome between local flap versus free flap. Materials and Methods. All patients admitted with lower limb open fractures were retrospectively reviewed. Patient notes were assessed for demographics, time to
The Radiographic Union Score for Hip (RUSH) is an outcome instrument designed to describe radiographic
Bone is a dynamic organ with remarkable regenerative properties seen only otherwise in the liver. However, bone healing requires vascularity, stability, growth factors, a matrix for growth, and viable cells to obtain effective osteosynthesis. We rely on these principles not only to
Bone is a dynamic organ with remarkable regenerative properties seen only otherwise in the liver. However, bone healing requires vascularity, stability, growth factors, a matrix for growth, and viable cells to obtain effective osteosynthesis. We rely on these principles not only to
Aim. The aim of this study was to define the role of implant material and surface topography on infection susceptibility in a preclinical in vivo model incorporating appropriate
Bone is a dynamic organ with remarkable regenerative properties seen only otherwise in the liver. However, bone healing requires vascularity, stability, growth factors, a matrix for growth, and viable cells to obtain effective osteosynthesis. We rely on these principles not only to
Bone is a dynamic organ with remarkable regenerative properties seen only otherwise in the liver. However, bone healing requires vascularity, stability, growth factors, a matrix for growth, and viable cells to obtain effective osteosynthesis. We rely on these principles not only to
Knee arthrodesis is a potencial salvage procedure for limb preservation in patients with multiple failures of Total Knee Arthroplasty (TKA) with massive bone loss and extensor mechanism deficiency. The purpose of the study is to evaluate the outcome of bridging knee arthrodesis using a modular and non cemented intramedullary nail in patients with septic failure Total Knee Arthroplasty. Between 2005 and 2013 (9 years), 15 patients (13 female and 2 male) with mean age 71.1 years (range 41 to 85) were treated at our Institution with septic two- stage knee arthrodesis using a modular and non- cemented intramedullary nail after multiple failures of septic Total Knee Arthroplasty. Mean follow- up was 70.1 months (24 to 108 months) with a minimum follow- up of 24 months. We evaluated the erradication of infection clinically and with normalization of laboratory parameters (ESR and CRP), limb length discrepancies and complications (periimplant
Greater trochanter fractures after total hip replacement have been reported in up to 5% of cases. The outcomes are generally poor. Treatment options include non-operative care or surgical treatment with cerclage wires or a claw plate. We present a simple tension band technique for acute fractures with a single bony fracture fragment. We have not used the technique for chronic or comminuted fractures. Technique: 2.5mm k-wires are passed through the fragment and anterior and posterior to the femoral implant. Eighteen-gauge wire is passed through a drill hole in the femur distal to the fracture and around the k-wires in a figure eight. The patient is kept 50% weightbearing with no active abduction for 4 weeks. In four cases the
The vast majority of
Stabilisation of a chronic pelvic discontinuity with a posterior column plate with or without an associated acetabular cage sometimes results in persistent micromotion across the discontinuity with late fatigue failure and component loosening. We believe that these chronic discontinuities are really chronic
Bone is a dynamic organ with remarkable regenerative properties seen only otherwise in the liver. However, bone healing requires vascularity, stability, growth factors, a matrix for growth, and viable cells to obtain effective osteosynthesis. We rely on these principles not only to
Supracondylar femur fractures are an uncommon but serious complication following TKA. The optimal treatment method often depends on the specific fracture pattern and various patient-related factors, and can be controversial in many cases. Nonoperative treatment can be considered in low-demand patients with minimally displaced fractures, whereas fractures associated with loose components typically require revision surgery. Displaced fractures with well-fixed implants can be treated successfully using one of several different strategies. Internal fixation after open or closed reduction can be achieved using either an intramedullary device or plate-and-screw constructs. Good results have been reported using intramedullary nails, although their use is limited to certain fracture patterns and implants designs. Modern periarticular locking plates featuring polyaxial locking screws can be inserted laterally in a submuscular fashion and offer the ability to achieve rigid fixation in the short distal fragment. These plates offer a robust treatment option for most
With the protection of crocodile species in Far North Queensland it was proposed that an increase in crocodile related injuries could be expected. The aim of this paper was to prospectively follow any crocodile injuries admitted for treatment at the Cairns Base Hospital and to establish a treatment regime for these injuries. A database was created in 2000 and patients admitted for treatment at the Cairns Base Hospital were followed prospectively. Prior to 2000 chart reviews were undertaken back to 1993. The injuries sustained, place of attack, wound infections and treatments were reviewed. Approval for this study was obtained from the ethics committee. The majority of patients treated over that period of time were attacked in the wet season and occurred in the water or at the waters edge. All of the injuries were related to the extremities, except for a single case of multiple abdominal lacerations. All wounds were contaminated with positive swab cultures at the time of their initial debridement. Four of these wounds developed a deep infection. In the majority of wounds adequate debridement, temporary stabilisation, and subsequent definitive surgery and skin coverage (coupled with appropriate antibiotic coverage) related in fracture healing. Avoidance of attack is the best form of defence. If exposed to crocodile wounds then surgical debridement, antibiotic coverage with keflin, gentamicin and metronidazole and delayed stabilsation will result in successful
Bone demonstrates good healing capacity, with a variety of strategies being utilized to enhance this healing. One potential strategy that has been suggested is the use of stem cells to accelerate healing. The following databases were searched: MEDLINE, CENTRAL, EMBASE, Cochrane Database of Systematic Reviews, WHO-ICTRP, ClinicalTrials.gov, as well as reference checking of included studies. The inclusion criteria for the study were: population (any adults who have sustained a fracture, not including those with pre-existing bone defects); intervention (use of stem cells from any source in the fracture site by any mechanism); and control (fracture healing without the use of stem cells). Studies without a comparator were also included. The outcome was any reported outcomes. The study design was randomized controlled trials, non-randomized or observational studies, and case series.Aims
Methods
Open femoral fractures are uncommon, and there are very few reports in the literature which refer specifically to their management. The results of the treatment of 31 open femoral fractures with significant bone loss in 29 patients treated in a single Orthopaedic Trauma Unit were reviewed. All fractures underwent wound and bony debridement before skeletal stabilisation at restored femoral length, using primary locked intramedullary nailing or dynamic condylar screw fixation for diaphyseal or metaphyseal fractures respectively. Soft tissue closure was performed at 48 hours in the majority of cases, followed by elective bone grafting procedures for 13 of the fractures. All fractures achieved bony union at an average of 51 weeks (range 20-156 weeks). The time to fracture union and subsequent functional outcome were largely dependent upon the location, type and extent of the bone loss. Union was achieved more rapidly in fractures associated with wedge defects than those with segmental bone loss, and
Background. Absence of rotator cuff allows unbalanced muscle forces of the shoulder to cause vertical migration of the humeral head. The translation of the humerus causes impaction of articular surface against the acromion. The purpose of the study is to assess outcome of Cuff tear arthropathy (CTA) Hemiarthroplasty prosthesis in this group of patients. Methods. Retrospective review was undertaken in 42 patients who underwent Global CTA Hemiarthroplasty between Jan 2001-Jan 2009. The mean length of follow up was 6 years. Results. The patients at review showed statistically significant improvement in Forward Flexion, Abduction and Numerical Pain Rating. There were four revision surgeries and the overall survival rate at ten years was 89 %. There was statistically significant improvement (p < 0.05) in forward flexion abduction and Numerical rating scale (p 0.02). Although improvement was noted in external and internal rotation this was not statistically significant. There was one perioperative humerus fracture which required plating at the same time of surgery. The