Aims. This study, using a surgeon-maintained database, aimed to explore the risk factors for surgery-related complications in patients undergoing primary cervical spine surgery for degenerative diseases. Methods. We studied 5,015 patients with degenerative cervical diseases who underwent primary cervical spine surgery from 2012 to 2018. We investigated the effects of diseases, surgical procedures, and patient demographics on surgery-related complications. As subcategories, the presence of cervical kyphosis ≥ 10°, the presence of ossification of the posterior longitudinal ligament (OPLL) with a canal-occupying ratio ≥ 50%, and foraminotomy were selected. The surgery-related complications examined were postoperative upper limb palsy (ULP) with a manual muscle test (MMT) grade of 0 to 2 or a reduction of two grade or more in the MMT, neurological deficit except ULP, dural tear, dural leakage, surgical-site infection (SSI), and postoperative haematoma. Multivariate logistic regression analysis was performed. Results. The significant risk factors (p < 0.050) for ULP were OPLL (odds ratio (OR) 1.88, 95% confidence interval (CI) 1.29 to 2.75), foraminotomy (OR 5.38, 95% CI 3.28 to 8.82), old age (per ten years, OR 1.18, 95% CI 1.03 to 1.36), anterior spinal fusion (OR 2.85, 95% CI 1.53 to 5.34), and the number of operated levels (OR 1.25, 95% CI 1.11 to 1.40). OPLL was also a risk factor for neurological deficit except ULP (OR 5.84, 95% CI 2.80 to 12.8), dural tear (OR 1.94, 95% CI 1.11 to 3.39), and dural leakage (OR 3.15, 95% CI 1.48 to 6.68). Among OPLL patients, dural tear and dural leakage were frequently observed in those with a canal-occupying ratio ≥ 50%. Cervical rheumatoid arthritis (RA) was a risk factor for SSI (OR 10.1, 95% CI 2.66 to 38.4). Conclusion. The high risk of ULP, neurological deficit except ULP, dural tear, and dural leak should be acknowledged by clinicians and OPLL patients, especially in those patients with a canal-occupying ratio ≥ 50%. Foraminotomy and RA were dominant risk factors for ULP and SSI, respectively. An awareness of these risks may help surgeons to avoid surgery-related complications in these conditions. Cite this article: Bone Joint J 2021;103-B(1):157–163

Aims. The aim of this study was to explore risk factors for complications associated with dural tear (DT), including the types of DT, and the intra- and postoperative management of DT. Patients and Methods. Between 2012 and 2017, 12 171 patients with degenerative lumbar diseases underwent primary lumbar spine surgery. We investigated five categories of potential predictors: patient factors (sex, age, body mass index, and primary disease), surgical factors (surgical procedures, operative time, and estimated blood loss), types of DT (inaccessible for suturing/clipping and the presence of cauda equina/nerve root herniation), repair techniques (suturing, clipping, fibrin glue, polyethylene glycol (PEG) hydrogel, and polyglycolic acid sheet), and postoperative management (drainage duration). Postoperative complications were evaluated in terms of dural leak, prolonged bed rest, headache, nausea/vomiting, delayed wound healing, postoperative neurological deficit, surgical site infection (SSI), and reoperation for DT. We performed multivariable regression analyses to evaluate the predictors of postoperative complications associated with DT. Results. In total, 429/12 171 patients (3.5%) had a DT. Multivariable analysis revealed that PEG hydrogel significantly reduced the incidence of dural leak and prolonged bed rest, and that patients treated with sealants (fibrin glue and PEG hydrogel) significantly less frequently suffered from headache. A longer drainage duration significantly increased the incidence of headache, nausea/vomiting, and delayed wound healing. Headache and nausea/vomiting were significantly more prevalent in younger female patients. Postoperative neurological deficit and reoperation for DT significantly depended on the presence of cauda equina/nerve root herniation. A longer operative time was the sole independent risk factor for SSI and was also a risk factor for dural leak, prolonged bed rest, and nausea/vomiting. Conclusion. Sealants, particularly PEG hydrogel, may be useful in reducing symptoms related to cerebrospinal fluid leakage, whereas prolonged drainage may be unnecessary. Younger female patients should be carefully treated when DT occurs. Cite this article: Bone Joint J 2019;101-B:1115–1121

Introduction. Microdiscectomies and microdecompressions are traditionally defined as procedures performed with a small incision using magnification. There are no studies in the literature comparing the magnification techniques used in these operations. We compared magnifying loupes and microscopes as the senior author was trained with both instruments and was equally comfortable using both. Materials/Methods. This is a retrospective comparative study involving 51 consecutive patients in group A (loupes) and same number in group B (microscope). The study included all patients who had single level lumbar microdiscectomy or decompression in the period from the 11th of January 2009 to the 6th of April 2010. To avoid any bias, only patients who failed to attend their follow ups were excluded from the study. The senior author operated on all patients. We noted intra-operative and post-operative complications, further interventions, length of surgery and length of hospital stay. We conducted a telephone questionnaire to collect visual analysis score for pre-op and post-op pain and functional status to calculate Macnab's functional status score. 78 patients (75.6%) answered the questionnaire, 39 patients from each group. There was 1 dural leak in group A.1 patient had discitis in the group A and 1 patient had superficial infection in group B. 4 patients in group A and 1 patient in group B had residual pain requiring intervention. The average length of surgery was one hour and five minutes and one hour and eleven minutes, respectively. Mean hospital stay was 1.43 days and 1.78 days, respectively. The data in the group B was skewed due to one patient who stayed for 9 days after surgery. 25 patients (49%) in group A and 36 patients (70.5%) in group B returned to normal pre-prolapse function and physical activity within 3 months. Results. There were statistically significant differences found between the two groups with the rate of complications such as dural leak, deep infection and residual pain requiring intervention. Better visualization with microscope could explain the thoroughness of discectomy or decompression leading to less chance of persistent problems. The average length of surgery was slightly higher in the microscope group, as expected, due to draping and preparation time of microscope. Mean hospital stay was slightly higher in group B due to the average being skewed by one patient staying for nine days after operation. Moreover, statistically significant higher number of patients returned to pre-prolapse functional level within 3 months with the use of microscope

Intrathecal morphine (IM) is a common adjunct in paediatric spinal deformity surgery. We previously demonstrated with idiopathic scoliosis it provides safe and effective analgesia in the immediate postoperative period. This study represents our 25 year experience with IM in all diagnostic groups. Our prospective Pediatric Orthopaedic Spine Database (1993–2018) was reviewed to identify all patients undergoing spinal deformity surgery who received IM and who did not. Patients 21 years of age or less who had a posterior spinal fusion (PSF) with segmental spinal instrumentation (SSI), and received 9–19 mcg/kg (up to 1 mg) of IM were included. Early onset scoliosis surgical patients were excluded. We assessed demographics, pain scores, time to first dose of opioids, diagnoses, surgical time, paediatric intensive care unit (PICU) admission and IM complications (respiratory depression, pruritus, nausea/ vomiting). There were 986 patients who met inclusion criteria. This included 760 patients who received IM and 226 who did not. IM was not used for short procedures (< 3 hrs), respiratory concerns, unsuccessful access of intrathecal space, paraplegia, and anesthesiologist decision. Both groups followed the same strict perioperative care path. The patients were divided into 5 diagnostic groups (IM / non IM patients): idiopathic (578/28), neuromuscular (100/151), syndromic (36/17), and congenital scoliosis (32/21) and kyphosis (14/9). Females predominated over males (697/289). The first dose of opioids after surgery was delayed for a mean of 10.6 hrs in IM group compared to 2.3 hrs in the non-IM group (p=0.001). The postoperative pain scores were significantly lower in the IM groups in the Post Anesthesia Care Unite (p=0.001). Only 17 IM patients (2%) were admitted to the PICU for observation secondary to respiratory depression, none required re-intubation. None of the IM group were re-intubated. Forty-nine patients (6%) experienced pruritus in the IM group compared to 4 of 226 patients (2%) in the non IM group. There were 169 patients (22%) of the IM patients and 21 patients (9%) of the non IM had nausea and vomiting postoperatively. Three patients (0.39%) had a dural leak from the administration of IM but did not require surgical repair. There were no other perioperative complications related to the use of IM. There were no significant group differences. Pre-incision IM is a safe and effective adjunct for pain management in all diagnostic groups undergoing spinal surgery. The IM patients had lower pain scores and a longer time to first administration of post-operative opioids. Although there is an increased frequency of respiratory depression, pruritus, and nausea/vomiting in the IM group, there were no serious complications

Introduction. Given the rising incidence of obesity in the adult population, it is more than likely that orthopaedic surgeons will be treating more obese patients with lumbar disc pathologies. The relationship between obesity and recurrent herniated nucleus pulposus (HNP) following microdiscectomy remains unclear. Objectives. To investigate the relationship between obesity and recurrent HNP following lumbar microdiscectomy. Methods. A retrospective review of case notes from 2008–2011 was conducted for all patients that underwent one level lumbar microdiscectomy, performed by a single surgeon. The standard criteria for microdiscectomy were used. Patient demographics, including Body Mass Index (BMI), collected from notes. Obese patients classified as BMI >/= 30. The primary clinical outcome measure was evidence of recurrent HNP on post operative MRI scan requiring further surgery. Results. A total of 283 patients were available for analysis: 190(67%) were in the non-obese group and 93 (32.9%) in the obese group. The average BMI was 28.1 and the average length of stay was 1.3days. Dural leak was seen in 11 patients(3.9%) out of which 8(4.2%) occurred in the non-obese group and 3(3.2%) in the obese group [p=0.04]. Recurrent symptomatic HNP was seen in 27(9.5%) patients confirmed by MRI scan. 19(10%) were in the non-obese group and 8(8.6%) in the obese group [p>0.8]. Conclusion. Obesity was not a predictor of recurrent HNP after lumbar microdiscectomy and did not have increased complication rates compared to the non-obese group

Objectives. To demonstrate that instrumented fusion of the paediatric cervical spine is possible and can be performed safely. Study Design. A retrospective review of paediatric patients who had instrumented fusion of the cervical spine. Materials and method. Sixteen paediatric patients (10 male, 6 female) with a mean age of 8 years who underwent instrumented cervical fusion were retrospectively reviewed. Surgery was performed for trauma (5 cases), spinal tuberculosis (3 cases), congenital anomalies (6 cases) and malignancies (2 cases). Fixation methods included occipito-cervical fusion, pedicle and lateral mass screws and anterior cervical plating. Ten posterior approaches, four anterior approaches and four combined anterior and posterior approaches were performed. We looked at fusion rates, blood loss, levels fused, theatre time, technique and complications. Results. All patients achieved radiological and clinical fusion. The average number of levels fused was 2.5, blood loss 418ml and theatre time 222 minutes for all patients. Anterior procedures had an average of 1 levels fused, blood loss 117ml and theatre time 98 minutes. Posterior procedures had an average number of 1.9 levels fused, blood loss of 306ml and theatre time of 131 minutes. For the combined anterior and posterior procedures the average levels fused were 5.5, blood loss 975ml and theatre time 248 minutes. Five surgery related complications were encountered. These consisted of dural leaks and wound sepsis which were all treated effectively. Conclusion. The use of modern segmental spinal instrumentation in the paediatric cervical spine is a viable option in this young population. Although our study sample was small we are able to demonstrate that no major surgical complications were encountered due to the use of cervical spinal instrumentation. NO DISCLOSURES

Aim. A retrospective review of the management of giant thoracic discs and report of their outcomes. Method. Giant thoracic disc have been defined as disc compressing more than 60% of the canal diameter. Although discectomy may lead to improvement of clinical symptoms it can be complicated by approach related morbidity especially when discs are calcified. Between 2007 and 2010 there were a total of 7 patients treated with a giant thoracic disc. A retrospective review of demographic data, symptoms, details of surgery, pre and post operative radiology, pre and postoperative Nurick scores, ODI and pain score, length of stay, complications and follow-up data were collected in all patients. Results. The average duration of symptoms was 8.5 months with a mean age of 58 years. Six patients (85%) presented with myelopathy, difficulty in walking and motor weakness. Discs were located at T5/6-2, T7/8-1, T8/9-1, T9/10-2 and T10/11-1 levels. Four (58%) discs were calcified and 3 (42%) were adherent to the dura. The average disc encroachment into the spinal canal was 81% (range: 67%-92%). All patients had a right mini thoracotomy and none of the patients were instrumented. All patients were followed up for a minimal of 24 months (range: 18 to 36 months). Improved Nurick, pain and ODI scores were seen in all patients. Average duration of stay was 4 days (range: 3-9 days). Only one patient had a dural leak and pseudo-meningocele with a calcified adherent disc. Successful dural reconstruction was done in 2 more patients with calcified disc. Two patients had post-operative thoracotomy pain needing pain management. No clinical deterioration was seen in any of the patients and all patients improved in their motor power and myelopathy. Conclusions. Mini-thoracotomy for treatment of giant thoracic disc herniations is associated with improvement of motor power and myelopathic symptoms with an acceptable rate of complications. Experienced team and careful surgical planning leads to success. For a single level surgery no instrumentation is required as suggested in most series

Spinal surgery in obese and morbidly obese patients can be challenging to the operating surgeon. One of the major problems is obtaining a good surgical access. We have used the synframe retractor system in patients undergoing spinal fusion and have found it especially useful in obese and morbidly obese patients. This study reports our experience. Seventy-seven consecutive obese and morbidly obese patients that underwent spinal decompression and fusion were reviewed. Patient selection was based on BMI values. Those with a BMI of more than thirty were included in the study. There were thirty-eight females and twenty-five males with an age of twenty-one to eighty-one years. Patient charts were used to acquire information regarding age,weight,height,gender,time in surgery, procedure start and end time,and departure. Postoperative complications and length of hospital stay were also recorded. Anesthesia notes were used to determine ASA scores,number of preoperative morbidities,and intraoperative blood loss. The synframe was used on all the patients. It is a retractor system which consists of a ring placed around the surgical site. It is fixed to both sides of the operating table with arms. Using retractor blades, the ring allows 360 degree access to the surgical exposure from any side. The set up tme for obese patients was 59.8 minutes and 73.5 minutes for morbidly obese patients. The surgical time and blood loss was only marginally higher in these two groups than in normal weighted patients. The average postoperative length of hospitalisation was 5.8 days. The surgical incision length averaged 7.8 cms for single level and 11.5 for two level fusions. 44% patients suffered a complication. These included cage migration due to a fall, wound infection, dural leak,pulmonary embolism, deep vein thrombosis etc. No significant weight loss was recorded following the surgery. Obese patients are a surgical challenge due to the comorbidities and difficulty in positioning and gaining good surgical access. The use of synframe retractor system improves surgical access, thereby reducing surgical time and blood loss. The surgical incision length was also comparable to normal weighted patients using this system. No significant weight loss was recorded following surgery. The high complication rate can be attributed to the associated comorbidities

Study Design: Retrospective chart review. Objective: To assess the clinical and radiological outcome of surgery for both dystrophic and non-dystrophic curves resulting from neurofibromatosis Type I.:. Subjects: 10 patients (7 females, 3 males) underwent surgical correction for neurofibromatous kypho-scoliosis between 1997–2003. The mean age at surgery was 16 years (range 8–37 years). Average follow-up 20 months (range 9 months – 4.5 years). Seven patients had MRI proven dystrophic curves (group I). These underwent 2–3 level apical vertebrectomy, followed by 2–3 weeks in Halo traction, followed by instrumented posterior spinal fusion and anterior rib strut grafting. Three patients had non-dystrophic curves (group II). Two underwent posterior instrumented fusion and one (aged 8 years) underwent convex epiphyseodesis with posterior Luque trolley. Outcome Measures: Cobb angle, thoracic kyphosis, lumbar lordosis, global apical vertebral translation (AVT), regional AVT, coronal and sagittal balance, complications and Modified SRS Outcomes Instrument completed at final follow. Results: For the dystrophic curves the Cobb angle improved from a mean of 81.5 degrees (mean bending film to 76 degrees) to 26.6 degrees post-operatively (68% correction) and 35.8 degrees at final follow-up (56% correction) and the global AVT improved from 61.5 mm to 29 mm at final follow-up. The average score for the modified SRS outcome instrument was 91.6 (Good). For the non-dystrophic curves the Cobb angle improved from a mean of 57.5 degrees (mean bending film to 47 degrees) to 23.5 degrees post-operatively ( 60% correction) and 24.6 degrees at final follow-up (57% correction) and the global AVT improved from 56.8 mm to 27.8 mm at final follow-up. The average score for the modified SRS outcome instrument was 98.5 (Good). All complications occurred in the dystrophic group including superficial infection in 2, dural leaks in 3, temporary brachial plexus injury in 1, worsening of lower limb neurological deficit in 1 and one death (upper GI haemorrhage). There was no failure of metalwork or evidence of pseudarthrosis identified. Seven of eight patients stated that they would have the surgery done again. Conclusions: Non-dystrophic curves maybe treated by posterior fusion alone achieving 60% Cobb correction and 55% AVT correction. Close observation should be maintained for the appearance of dystrophic features and deterioration of correction. Dystrophic curves should be treated early and aggressively by two/three stage apical vertebrectomy, grafting and posterior spinal fusion. In this series 68% coronal Cobb and 63% AVT correction was achieved post-operatively. Complications can be expected with scoliosis associated with more than 50 degrees of kyphosis

Aims

Orthopaedic and reconstructive surgeons are faced with large defects after the resection of malignant tumours of the sacrum. Spinopelvic reconstruction is advocated for resections above the level of the S1 neural foramina or involving the sacroiliac joint. Fixation may be augmented with either free vascularized fibular flaps (FVFs) or allograft fibular struts (AFSs) in a cathedral style. However, there are no studies comparing these reconstructive techniques.

We describe a modified technique of micro-decompression of the lumbar spine involving the use of an operating microscope, a malleable retractor and a high-speed burr, which allows decompression to be performed on both sides of the spine through a unilateral, hemi-laminectomy approach. The first 100 patients to be treated with this technique have been evaluated prospectively using a visual analogue score for sciatica and back pain, the MacNab criteria for patient satisfaction, and functional assessment with the Oswestry Disability Index.

After a period of follow-up from 12 months to six years and four months, sciatica had improved in 90 patients and back pain in 84 patients. Their result was graded as good or excellent by 82 patients according to the MacNab criteria, and 75 patients had subjective improvement in their walking distance. Late instability developed in four patients.

Lumbar micro-decompression has proved to be safe, with few complications. Postoperative instability requiring fusion was uncommon, and less than using traditional approaches in published series.