Introduction. In total hip arthroplasty, a high radiographic inclination angle (RI) of the acetabular component has been linked to short- and long-term complications. There are several factors that lead to RI outliers including cup version, pelvic orientation and angle of the cup introducer relative to the floor. The primary aim of this study was to analyse what increases the risk of having a cup with an RI outside the target zone when controlling cup orientation with a digital inclinometer. Methods. In this prospective study, we included 200 consecutive patients undergoing uncemented primary THA in the lateral decubitus position using a posterior approach. Preoperatively, the surgeon determined the target intraoperative inclination (IOI. target. ). The intra-operative inclination of the cup (IOI. cup. ) was measured with the aid of a digital inclinometer after seating of the acetabular component. Anteroposterior pelvic radiographs were made to measure the RI of the acetabular component. The target zones were defined as 30°-45° and 35°-45° of RI. The operative inclination relative to the sagittal plane of the pelvis (OI. math. ) was calculated based on the radiographic inclination and anteversion angle. The difference between two outcome measures was expressed as Δ. Results. The mean RI was 37.9° SD 4.7, there were 12 cases with RI outside the 30°– 45° zone (6%) and 53 outliers (26.5%) with RI outside the 35°-45° zone. The mean absolute ΔIOI. cup. -IOI. target. was 1.2° SD 1.0. The absolute ΔIOI. cup. -IOI. target. was less than 1° in 108 patients (54%), less than 2° in 160 patients (80%), less than 3° in 186 patients (93%), and in 14 patients (7%) the difference was 3°-5°. The mean pelvic motion (ΔOI. math. -IOI. cup. ) was 8.8° SD 3.9 (95% CI 8.2° to 9.3°). The absolute deviation from the mean ΔOI. math. -IOI. cup. , which corresponds with the amount of pelvic motion, was significantly higher in RI outliers compared with non-outliers for both the 30°-45° and 35°-45° inclination zone (7.4° SD 3.3 vs 2.8° SD 2.1 and 4.7° SD 2.8 vs 2.5° SD 2.0 respectively) (p<0.0001). A linear regression analysis demonstrated a strong correlation between ΔOI. math. -IOI. cup. and the RI of the cup (r. 2. =0.70; P<0.0001). A multiple regression was run to predict ΔOI. math. -IOI. cup. from gender, BMI, side and hip circumference. These variables statistically significantly predicted ΔOI. math. -OIa. cup. , F(4, 195) = 19,435, p<0.0001, R2 = 0.285, but only side (p=0.04) and hip circumference (p<0.0001) added statistically significantly to the prediction. Discussion and Conclusion. When using a digital inclinometer 94% of cups had a RI within a 30°-45° zone and 73.5% of cups within a 35°-45° zone using a predefined IOI. target. based on the patient's hip circumference. The difference between the IOI. target. and the IOI. cup. of the acetabular component was less than 3° in 93% and less than 5° in all patients signifying that the surgeons were able to implant the cup close to their chosen intra-operative orientation. Deviation from the mean ΔOI. math. -IOI. cup. was significantly bigger in the RI outliers indicating that RI outliers were caused by more or less than deviation of the sagittal plane of the pelvis at time of cup impaction

Native anatomy of the arthritic hip is an important consideration in hip replacement surgery and implant design. Acetabular component orientation in total hip replacement (THR) is the single greatest factor that influences dislocation rate. Detailed knowledge regarding orientation of the native acetabulum is therefore essential. Native acetabular orientation in healthy hips is well documented but we could not find any papers detailing native acetabular orientation in the arthritic hip. A commercially available computer navigation system (Orthopilot BBraun Aesculap, Tuttlingen, Germany) was used to assess acetabular inclination and anteversion in 65 hips with symptomatic arthritis requiring THR. Acetabular inclination in all hips was also measured on pre op anteroposterior pelvic radiographs. Patients with DDH were excluded. All patients were Caucasian and had primary osteoarthritis, 29 males and 35 females. Average age 68(SD 8). Mean values as recorded by computer navigation were: inclination 51.4°(SD 7.1); anteversion 11.7°(SD 10.7). As recorded from radiographs mean acetabular inclination was 58.8°(SD 5.7). There was a difference between males and females. Mean navigated inclination: male 50.5°(SD 7.8); female 52.1°(SD 6.7). Mean navigated anteversion: male 8.3°(SD 8.7); female 14.39°(SD 11.6) Mean radiographic inclination: male 57.4°(SD 5.1) and female 59.8°(SD 6). Natural acetabular orientation in arthritic hips falls out with the safe zones defined by Lewinnek. When compared with healthy hips, as described in current literature, the arthritic hip appears to have a smaller angle of inclination and anteversion, by approximately 5° and 10° respectively, in both males and females. This is useful when positioning the cup during surgery. The difference between males and females, particularly in terms of anteversion, should also be considered