Introduction. Over the past several decades, numerous surgical procedures have been perfected in the inpatient hospital setting and then evolved into outpatient procedures. This has been shown to be a safe and economical transition for many orthopedic procedures. A prime example is ACL reconstruction. We report here our early experience with our initial consecutive series of outpatient UKA's done in a free standing ASC (ambulatory surgery center). Materials and Methods. From 8/26/2008 to 5/20/12 there were 60 UKA's performed as outpatient procedures at a free standing ASC. Average patient age was 57.7 years (range of 46–69). Medical comorbidities included 22 patients with HTN and 7 with diabetes. All patients had general anesthesia with periarticular injection of the involved knee (25 cc's of Marcaine with epinephrine 1:100,000) and an intraarticular injection after closure of the capsule with 25 cc of Marcaine with epinephrine mixed with 5 cc of morphine sulfate. Patients without allergy to sulfa were given 200mg of Celebrex bid for three days and hydrocodone/acetaminophin 10/325 1–2 tabs q4 hours prn pain. Patients were discharged home when stable, ambulating with aids as needed, with length of stay ranging from 60–180 minutes (average of 85 minutes). Results. No patients required admission to the hospital for any reason. There was one hemarthrosis in a medial UKA which developed on postoperative day 4. There was uneventful resolution of this event with conservative management and an excellent result was achieved. The vast majority of patients were ambulating well and without walking aids at the 2 week postoperative evaluation. The total number of UKAs performed by the author in the ASC since 8/26/2008 is now 282, still without any complications requiring admission to the hospital. Conclusion. Outpatient UKA performed in an ambulatory surgery center was found to be a safe, efficient, and effective method for the management of
