Aim. Treatment recommendations for periprosthetic joint infections (PJI) include surgical debridement, antibiotic therapy or staged revision. In surgical related foot and ankle infections (SR-FAI), implant removal will lead to instability. Debridement is difficult because the implant is outside the joint. Recommendations regarding PJI treatment can therefore not be extrapolated to the treatment of SR-FAI. Method. We searched PubMed for the etiology and treatment of SR-FAI, taken into account the time of occurrence, causative microorganisms and surgical treatment options. We integrated this knowledge into a treatment algorithm for SR-FAI. Results. Within the first 6 weeks after surgery, it is difficult to distinguish acute osteomyelitis from surgical site infection in which infection is limited to the soft tissue. The predominantly causative microorganism is Staphylococcus aureus. No debridement can be performed, because of the diffuse soft tissue inflammation and the absence of a joint space. If early SR- FAI is suspected without signs of systemic symptoms, fistula or abscess, empirical antibiotic treatment covering Staphylococcus aureus is recommended. If there is suspicion of ongoing SR-FAI after 2 weeks of empirical treatment, samples for culture after an antibiotic free window should be obtained to identify the causative microorganisms. If SR-FAI is confirmed, but there is no consolidation yet, targeted antibiotic treatment is given for 12 weeks without initial implant removal. In all other cases, debridement and samples for culture should be obtained after an antibiotic free window. Staged revision surgery will be performed if there is still a nonunion. Conclusions. Treatment algorithm regarding PJI cannot be extrapolated to the treatment of SR-FAI. Until now, no treatment guideline for SR-FAI is available. We have introduced a treatment algorithm for the treatment of SR-FAI. The guideline will be validated during the next 2 years

The most common classification of periprosthetic femoral fractures is the Vancouver classification. The classification has been validated by multiple centers. Fractures are distinguished by location, stability of the femoral component, and bone quality. Although postoperative and intraoperative fractures are classified using the same three regions, the treatment algorithm is slightly different. Type A fractures involve the greater and lesser trochanter. Fractures around the stem or just distal to the stem are Type B and subcategorised depending on stem stability and bone quality. Type C fractures are well distal to the stem and are treated independent of the stem with standard fixation techniques. The majority of fractures are either B1 (stable stem) or B2 (unstable stem). The stem is retained and ORIF of the fracture performed for B1 fractures. B2 and B3 fractures require stem revision with primary stem fixation distal to the fracture. Intraoperative fractures use the same A, B, C regions but are subtyped 1–3 as cortical perforations, nondisplaced, and displaced unstable fractures, respectively. With the exception of A1 intraoperative fractures all other intraoperative fractures require surgical treatment. A recent publication utilizing a New York state registry highlighted the patient risk of mortality associated with periprosthetic hip fractures. One month, 6 month and 1 year mortality was 3.2%, 3.8% and 9.7%, respectively. The mortality risk was lower for periprosthetic fractures treated with ORIF at 1 and 6 months compared to fractures requiring revision total hip

Important issues related to total hip replacement for dysplasia are: placement of the cup and bone stock; the role of femoral osteotomy, and the choice of acetabular and femoral components.

The cup can be placed at the correct or near correct anatomical level with or without a bone graft, in a high position (high hip center) or at the right level in a protruded position. All three techniques can provide adequate coverage of the cup. In the high hip position bone graft is not usually necessary to obtain cup coverage. There is, however, a higher rate of component loosening, a higher dislocation rate, and lengthening is limited to the femoral side. Placing the cup in a protruded position to obtain coverage does not restore bone stock for future surgery, but it does place the hip at the correct level. Placing the cup in the correct anatomical position (i.e., at the right level and not protruded) may require a structural autograft which adds to the complexity of the case. However, bone stock is restored for future surgery.

Femoral osteotomy may be used as part of the exposure for diaphyseal shortening or for derotation of excessive anteversion. The osteotomy is carried out in the sub-trochanteric region and may be oblique, step-cut or transverse. Fixation of the osteotomy is achieved via the stem, a plate, or a cortical strut.

Cementless components are usually used because of the relatively young age of this patient population. Small components may be necessary. On the femoral side, the stem should be straight or modular so excessive anteversion can be neutralised.

Treatment of Tendo Achilles (TA) ruptures can result in considerable morbidity and has significant socio-economic implications. The ideal management of these injuries has yet to be defined. Recent studies have demonstrated that non-surgical treatment with accelerated rehabilitation may have comparable outcomes to surgery. The aim of this study was to evaluate current management and outcomes of TA ruptures at a tertiary referral centre, with a view to developing contemporary treatment guidelines.

A retrospective review of TA ruptures over a 12-month period was undertaken. Patients were managed on an individual based approach with no strict management algorithm followed. Data collection included pre-injury activity level, ultrasound findings and treatment methodology. Outcome data collected included return to activity, incidence of DVT and re-rupture. Patients were followed up for an average of 2 years.

Data was collected in 49 patients. 31 (63%) of these were managed non-surgically. Ruptures were most common in men (65%) at an average age of 44 yrs. Ultrasound scan at initial diagnosis was performed in 28 patients. There was an average gap in equinus of 34mm in the surgical group, while the average gap within the non-surgical group was 24mm (p=0.23). There was no association between the gap observed on ultrasound and re-rupture rate.

At a median of 2 year follow up, there was no significant reduction in average time spent immobilised in a below knee splint in the surgically treated group (10.2 weeks) compared to non-surgical group (10.9 weeks, p=0.35). 86.3% of patients returned to pre-injury level of activity in the non-surgical group and 86.7% in the surgery group (p=1.0). Complications within this patient cohort consisted of one superficial wound infection and one re-rupture, both occurring within the surgical group. Within the surgical group patients were treated with direct primary repair or primary reconstruction using FHL augmentation in cases of delayed presentation. DVT was not observed in either group. Only 22.6% received thromboprophylaxis in non-surgical group compared to 61.1% in surgical group.

We observed that patients within the non-surgical group demonstrated the same return to pre-injury activity as the surgically treated group and had fewer complications. The time spent immobilised was also comparable. Based on these findings, we modified guidelines and now recommend that surgery should be limited to patients with gap of greater than 20 mm in full equinus on ultrasound and in those with delayed diagnosis. We also recommend thromboprophylaxis for 2 weeks in non-surgical group.

The Vancouver classification separates periprosthetic femur fractures after THA into three regions (A - trochanteric, B - around or just below the stem, and C - well below the stem), with fractures around or just below the stem further separated into those with a well-fixed (B1) or loose stem and good (B2) or poor (B3) bone stock. Trochanteric fractures may be associated with osteolysis and require treatment that addresses osteolysis as well as ORIF of displaced fractures. Fractures around a well-fixed stem can be treated with ORIF using cerclage or cable plating, while those around a loose stem require implant revision usually to a longer cementless tapered or distally porous coated cementless stem. Fractures around a loose stem with poor bone stock in which salvage of the proximal femur is not possible require replacement of the proximal femur with an allograft prosthetic composite or proximal femoral replacement. Fractures well below the stem can be treated with conventional plating methods.

Periprosthetic acetabular fractures are rare and usually occur in the early post-operative period or late as a result of osteolysis or trauma. These can generally be separated into those with a stable acetabular component which can be treated non-operatively, and those with an unstable component often with discontinuity or posterior column instability which require complex acetabular reconstruction utilizing plating or revision to a cup-cage.

Introduction

We propose that Total Hip Replacement with correction of fixed flexion deformity of the hip and exaggerated lumbar lordosis will result in relief of symptoms from spinal stenosis, possibly avoiding a spinal surgery. A sequence of patients with this dual pathology has been assessed to examine this and suggest a possible management algorithm.

Aim. At present, a variety of clinical guidelines for treatment of periprosthetic joint infections (PJI) inevitably lead to a variety in outcomes by differing case management. Ideally a treatment algorithm should incorporate all components contributing to the decision-making process for a patient tailored solution in PJI. We aim to present a comprehensive and reproducible treatment algorithm based on a validated staging system, a thorough understanding of the host, the causative microbiome and implant complexity. Method. The diagnosis of a PJI was defined according to major and minor criteria following revised International Consensus Symposium algorithm. The validated McPherson staging system was used in our university hospital from January 2015 until January 2019 in referred PJI patients. Standardised preoperative and postoperative survey documents were completed in order to register data from the patient's medical, social and surgical history. The complexity of the infected implant was taken into consideration, including quantity of preceding procedures, residual bone stock, type of fixation, magnitude of prosthetic components and presence or absence of reconstructive options. Further, preoperatively obtained bacteriological information by means of arthrocentesis or tissue/bone biopsies was categorized according to the mono- or polybacterial nature and to the qualification of virulence and difficulties to treat. Social and professional history, financial impediments and patient's functional outcome wishes were included in the joint decision making. Results. We present our comprehensive PJI treatment algorithm. The ‘deTerminators’ we included are a validated staging system focused on the host, the amount of unsuccessful prior attempts, the difficult to treat character of the microbiome, the implant complexity, anatomical location and socioeconomic patient derived factors. Furthermore, we call for source control by minimally invasive means or late DAIR in complex case management combined with lifelong suppressive antibiotic therapy with maintenance of quality of life as the main outcome instead of curative intention. Conclusions. We present a comprehensive treatment algorithm based on an expanded McPherson staging system coupled with bundled clinical, technical, social and psychological data which should assist the surgeon and the patient to make informed choices. We hope that usage and testing of our algorithm in other centers could further demonstrate its usefulness

Introduction. The reconstruction of segmental long bone defects remains one of the holy grails of orthopaedic surgery. The optimal treatment of which remains a topic of great debate. This study aimed to evaluate the outcomes following the management of critical-sized bone defects using a classification-based treatment algorithm. Materials & Methods. A retrospective review of all patients undergoing treatment for segmental diaphyseal defects of long bones at a tertiary-level limb reconstruction unit was performed. The management of the bone defect was standardised as per the classification by Ferreira and Tanwar (2020). Results. A total of 96 patients (mean age 39.8, SD 15.2) with a minimum six months follow-up were included. Most bone defects were the result of open fractures (75/96) with 67% associated with Gustilo-Anderson IIIB injuries. There was a statistical difference in the likelihood of union between treatment strategies with more than 90% of cases undergoing acute shortening and bone transport achieving union and only 72% of cases undergoing the induced membrane technique consolidating (p=0.049). Of those defects that consolidated, there was no difference in the time to bone union between strategies (p=0.308) with an overall median time to union 8.33 months (95% CI 7.4 — 9.2 months). The induced membrane technique was associated with a 40% risk of sepsis. Conclusions. This study reported the outcomes of a standardised approach to the management of critical-sized bone defects. Whilst overall results were supportive of this approach, the outcomes associated with the induced membrane technique require further refinement of its indications in the management of critical-sized bone defects

Acetabulum fractures caused by civilian firearms represent a unique challenge for orthopaedic surgeons. Treatment strategies should include the assessment of infection risk due to frequently associated abdominal injuries and maintenance of joint function. Still, internationally accepted treatment algorithms are not available. The aim of the study was to increase knowledge about civilian gunshot fractures of the acetabulum by describing their characteristics and management at a high-volume tertiary hospital. All adult patients admitted to our hospital between January 2009 and December 2022 with civilian gunshot fractures of the acetabulum were included in this descriptive retrospective study. In total our institution treated 301 patients with civilian gunshot fractures of the hip joint and pelvis during the observation period, of which 54 involved the acetabulum. Most patients were young males (88,9%) with a mean age of 29 years. Thirty patients (55,6%) had associated intraabdominal or urological injuries. Fracture patterns were mostly stable fractures with minor joint destruction amenable to conservative fracture treatment (n=48, 88,9%). Orthopaedic surgical interventions were performed in 21 patients (38,9%) with removal of bullets in contact with the hip joint via arthrotomy or surgical hip dislocation as most frequent procedures. Most patients received antibiotics on admission (n=49, 90,7%). Fracture related infections of the acetabulum were noted in six patients (11,1%) while the mortality in the study population was low with one demised patient (1,9%) due to the trauma burden. Most civilian acetabulum gunshot fractures are associated with intraabdominal or urological injuries. In comparison to the literature on extremity gunshot fractures, there is an increased risk of infection in our study population. The decision for surgical wash-out and bullet removal should be based on contamination and anticipated joint destruction, while osteosynthesis or primary arthroplasty are rarely necessary for these injuries

Aim. Musculoskeletal infection is a serious complication, however literature is lacking prospective data on its impact on mental health. The study aimed to assess mental health in patients with musculoskeletal infections and how they experience the possible mental and physical impairment. Method. All patients treated in our unit for musculoskeletal infections between July 2020 and March 2022 were prospectively included. To assess specific patient reported outcomes the following questionnaires were used: World-Health-Organization Quality-Of-Life (WHOQOL)-BREF and the Veterans-RAND-12Item Health Survey (VR-12) for mental & physical health; Patient-Health-Questionnaire (PHQ-8) for depression symptoms; Generalized-Anxiety-Disorder-Scale-7 (GAD-7) for anxiety symptoms and Somatic-Symptom-Disorder-B Criteria Scale (SSD-12) for experience of mental & physical impairment. The surveys were conducted at baseline, 6 and 12-weeks and 1-year. Results. In total 199 patients were included (31 fracture-related infections, 80 prosthetic joint infections, 40 diabetic foot syndromes and 48 other musculoskeletal infections). Physical health was significantly worse 6 weeks after treatment compared to baseline (WHOQOL p=.002; VR-12 p<.001), but significantly better at 3-months (p<.001; p=.006) and 12-months (p=.003; p<.001). Mental health was significantly worse at 3-months (WHOQOL p=.002), but at final follow-up significantly better (VR-12 p=.046). Social relationships (domain of WHOQOL) were perceived significantly worse 6 weeks and 12 months after treatment initiation (p=.003; p=.007), as were environmental factors. At baseline moderate to severe depression symptoms (PHQ-8≥10) and moderate to severe anxiety symptoms (GAD-7≥10) were observed in 14.6%, respectively 10.6% of all patients. At 12-months these were 7.4% and 3%. Over the course of treatment, only patients with DFS showed a significant change in experienced psychological or physical impairment, which was perceived significantly less compared 6 weeks to 12 months (p=.042). Conclusions. Patients with musculoskeletal infections suffer from a considerable impact on their mental health. The greatest impairment in physical health was seen 6 weeks after beginning of treatment. The psychological well-being was worse at 3-months. Environmental factors, such as mobility, activities of daily living and dependence on medication or medical treatment were worst at 3-months. Also increasingly worse social relationships over the course of treatment was observed. Further studies are needed to identify psychological impairment and related factors, as well as to determine how patients cope with their disease and treatment. This could serve as a foundation to implement treatment algorithms in order to improve patient related outcome and quality of life

Aim. Treatment algorithms for fracture-related nonunion depend on the presence or absence of bacterial infection. However, the manifestation of septic nonunion varies. Low-grade infections, unlike manifest infections, lack clinical signs of infection and present similarly to aseptic nonunion. The clinical importance of low-grade infection in nonunion is not entirely clear. Therefore, the aim of this study was to evaluate the clinical relevance of low-grade infection in the development and management of femoral or tibial nonunion. Method. A prospective, multicenter clinical study enrolled patients with nonunion and regular healed fractures. Preoperatively, complete blood count without differential, C-reactive protein (CRP), and procalcitonin were obtained, clinical signs of infection were recorded, and a suspected septic or aseptic diagnosis was made based on history and clinical examination. During surgical nonunion revision or routine implant removal, tissue samples were collected for microbiology and histopathology, and osteosynthesis material for sonication. Nonunion patients were followed for 12 months. Definitive diagnosis of “septic” or “aseptic” nonunion was made according to diagnostic criteria for fracture-related infection, considering the results of any further revision surgery during follow-up. Results. 34 patients with regular healed fractures were included. 62 nonunion patients were diagnosed as aseptic, 22 with manifest, and 23 with low-grade infection. The positive predictive value was 88% and the negative predictive value 72% for the suspected diagnosis. The nonunion groups had significantly higher CRP levels than the regular healer group. Differentiation between septic and aseptic nonunion based on blood values was not possible. Low-grade infection demonstrated less frequently histopathologic signs of infection than manifest infection (22% vs. 50%, p=0.048), with 15% of regular healers having histopathologic signs of infection. Cutibacterium acnes was less present in manifest compared to low-grade infection (p=0.042). Healing rates for septic nonunion involving C. acnes were significantly lower for manifest infection (20%) than for low-grade infection (100%, p=0.002). Patients with low-grade infection were treated with systemic antibiotics less frequently than patients with manifest infection (p=0.026), with no significant difference in healing rate (83% vs. 64%), which was slightly lower for low-grade infection than for aseptic nonunion (90%). Conclusions. Low-grade infections play a significant role in nonunion development and are difficult to diagnose preoperatively due to the lack of clinical signs of infection and unremarkable blood counts. However, our results imply that for low-grade infections, antibiotic therapy may not always be mandatory to heal the nonunion. This study was supported by the German Social Accident Insurance (FF-FR0276)

Aims. Ilizarov described four methods of treating non-unions but gave little information on the specific indications for each technique. He claimed, ‘infection burns in the fire of regeneration’ and suggested distraction osteogenesis could effectively treat infected non-unions. This study investigated a treatment algorithm for described Ilizarov methods in managing infected tibial non-union, using non-union mobility and segmental defect size to govern treatment choice. Primary outcome measures were infection eradication, bone union and ASAMI bone and function scores. Patients and Methods. A consecutive series of 79 patients with confirmed, infected tibial non-union, were treated with one of four Ilizarov protocols, consisting of; monofocal distraction (26 cases), monofocal compression (19), bifocal compression/distraction (16) and bone transport (18). Median non-union duration was 10 months (range 2–168). All patients had undergone at least one previous operation (mean 2.2; range 1–5), 38 had associated limb deformity and 49 had non-viable non-unions. Twenty-six cases (33%) had a new simultaneous muscle flap reconstruction at the time of Ilizarov surgery and 25 had pre-existing flaps reused. Treatment algorithm based on assessment of bone gap and non-union stiffness, measured after resection of non-viable bone. Results. The treatment algorithm was easy to apply, being based on easily assessable criteria. Infection was eradicated in 76 cases (96.2%) at a mean follow-up of 40.8 months (range 6–131). All three cases of infection recurrence occurred in the monofocal compression group. They required repeat excision and Ilizarov distraction in two cases and below-knee amputation in one. Union was achieved in 68 cases (86.1%) with the initial Ilizarov methods alone. Union was highest amongst the monofocal distraction and bifocal compression/distraction groups, 96.2% and 93.8% respectively. Mean external fixator time was 7.5 months (range 3–17). Monofocal compression was successful in only 73.7% of mobile non-unions, with significantly lower ASAMI scores and a 26.3% re-fracture rate. Bone transport secured union in 77.8% (14/18) but with a 44.4% unplanned reoperation rate. However, after further treatment, infection-free union following bone transport was 100%. Conclusion. We cannot recommend Ilizarov monofocal compression in the treatment of infected, mobile non-unions. Distraction (monofocal or bifocal) was effective and is associated with higher rates of union and infection clearance

Aim. Data of optimal management of infections after internal fixation (IIF) is scarce and long-term follow-up results often lack. We analyzed characteristics of infections after intramedullary (IIIF) and extramedullary long bone fixation (IEIF) and evaluated their infection and functional outcome. Method. Consecutive patients with IIF diagnosed at our institution from 01/2010-10/2017 were retrospectively included. Infection was defined as visible purulence, sinus tract, microbial growth in ≥2 independent samples or positive histopathology. The outcome was compared before and after implementation of a comprehensive surgical and antimicrobial treatment algorithm in 04/2013. Results. Of 127 patients, infection involved lower extremity in 111 patients (87%). Median age was 53 years (range, 19–89 years), 70% were men. Fixation was performed with intramedullary nail in 47 (37%) and with extramedullary osteosynthesis (plates, screws, pins) in 80 patients (63%). At infection diagnosis, the implant was in situ in 96 patients (76%), whereas 31 patients (24%) had residual osteomyelitis after implant removal. The time from bone fixation to infection was longer in IIIF than IEIF (25 vs. 7 months, p=0.027). Pain was reported in 55 patients (43%) and local infection signs in 96 patients (75%), including sinus tract in 46 patients, more commonly reported after IIIF than IEIF (49% vs. 29%, p=0.035). Infections were monomicrobial in 85 (67%), polymicrobial in 18 (14%) and culture-negative in 23 patients (18%). Most common pathogens were S. aureus (43%), coagulase-negative staphylococci (28%) and gram-negative rods (22%). Débridement (with device retention, if present) was performed in 40, device removal in 43, one-stage exchange in 16 and two-stage exchange in 20 patients. One patient had no surgery and 7 patients underwent limb amputation. 43 patients (34%) were treated before implementation of the interdisciplinary treatment concept and 84 patients (66%) afterwards. Among 111 patients with available follow-up (median, 5.2 months; range, 0.2–86 months), in 78 cases (70%) infection eradication was achieved (similar in IIIF and IEIF). However, overall infection and functional outcome was only 48% (53 patients). After implementation of the treatment algorithm, the infection outcome improved from 56% to 79% (p=0.03) and the overall success from 33% to 56% (p=0.016). Conclusions. Approximately half of infections after IIF failed in terms of infection eradication or restoration of function. After implementation of standardized surgical and antibiotic treatment concept, infection and functional outcome improved significantly. No significant differences between IIIF and IEIF was observed in terms of infection and functional success

Aim. Although non-unions being one of the most common complication after long-bone fracture fixation, the definition of this entity remains controversial and varies widely among authors. A clear definition is crucial, not only for the evaluation of published research data but also for the establishment of uniform treatment concepts. The aim of this systematic review was to identify the definitions and different criteria used in the scientific literature to describe non-unions after long bone fractures. Method. A comprehensive literature search was performed in PubMed, Cochrane Library, Web of Science, and Embase. according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Prospective therapeutic and diagnostic clinical studies in which adult long-bone fracture non-unions were investigated as main subject were included in this analysis. Results. One hundred fifty-two studies investigating 6432 long-bone non-unions met inclusion criteria for this analysis. In total 49% (75/152) of included studies did not define non-union at all, even though non-union was their main study subject. A definition of non-union on either clinical, radiologic or time criteria could be found in 51% (77/152) of the included studies. Non-union was defined based on time criteria in 83% (64/77), on radiographic criteria in 65% (50/77), and on clinical criteria in 43% (33/77). A combination of clinical, radiologic and time criteria for definition was only found in 35% (27/77) of all the included studies that defined non-union. The time point when authors defined an unhealed fracture as a nonunion showed a considerable heterogeneity, ranging from four to 24 months. Conclusions. In the current orthopaedic trauma literature, we found a lack of consensus with regard to the definition of long bones non-unions. Therefore, a standardized definition of non-union remains unclear. Without valid and reliable definition criteria of non-unions, the establishment of standardized diagnostic and treatment algorithms as well as the comparison of studies remain difficult. The lack of a clear definition emphasizes the need for consensus-based definition of fracture non-unions based on clinical, radiographic and time criteria

With cementless porous-coated acetabular replacements, extensive bone loss can occur without affecting implant stability. As a result, the surgeon is frequently faced with re-operating on a well-fixed cementless acetabular component with osteolysis and must decide whether or not to remove a well-fixed porous coated socket. A classification system and treatment algorithm has been developed to aid in management decisions regarding re-operation for polyethylene wear and pelvic osteolysis. Cases are classified into one of 3 possible categories depending on the radiographic stability of the porous coated shell and the ability to replace the polyethylene liner. Type I case; stable porous coated shell, liner replaceable; Type II case; socket stable, liner not replaceable; Type III case; socket loose, not osseointegrated. Relative Contra-indications for Liner Exchange – Type II Case - Malpositioned socket, Severely damaged shell or lock detail (consider cementing shell in place), Poor track record of the implant, Highly crosslinked polyethylene liner of adequate thickness not available, Ongrowth (as opposed to ingrowth) fixation surface. Treatment Algorithm. Type I Case: Retain well-fixed shell in Type I cases and replace the liner. Debride accessible lytic lesions and graft with allograft chips. Type II Case: Remove the well-fixed shell in Type II case. Assess defect once the shell is removed. Reconstruction based on the bony defect present. The vast majority can be revised with a larger porous coated socket. Type III Case: Remove loose socket. Assess defect and reconstruct based on the defect. There is a greater need for more extensive grafting and the use of reconstruction rings with Type III cases. This treatment algorithm has helped the authors successfully evaluate and treat a large series of patients with polyethylene wear and pelvic osteolysis in association with porous coated acetabular components. The stability of the acetabular component and appropriate knowledge of the implant are important factors that impact surgical management

Extensor mechanism complications after or during total knee arthroplasty are problematic. The prevalence ranges from 1–12% in TKR patients. Treatment results for these problems are inferior to the results of similar problems in non-TKR patients. Furthermore, the treatment algorithm is fundamentally different from that of non-TKR patients. The surgeon's first question does not focus on primary fixation; rather the surgeon must ask if the patient needs surgery and if so am I prepared to augment the repair? Quadriceps tendon rupture, periprosthetic patellar fracture, and patellar tendon rupture have similar treatment algorithms. Patients who are able to perform a straight leg raise and have less than a 20-degree extensor lag are generally treated non-operatively with extension bracing. The remaining patients will need surgical reconstruction of the extensor mechanism. Loose patellar components are removed. Primary repair alone is associated with poor results. Whole extensor mechanism allograft, Achilles tendon allograft, and synthetic mesh reconstruction are the current techniques for augmentation. In the acute setting if these are not available hamstring tendon harvest and augmentation is an option. Achilles tendons and synthetic mesh are easier to obtain than and entire extensor mechanism but are limited to patients that have an intact patella and the patella that can be mobilised to within 2–3 cm of the joint line. No matter which technique is used the principles are: rigid distal/tubercle fixation, coverage of allograft/mesh with host tissue to decrease infection, tensioning the augment material in extension, no flexion testing of reconstruction and post-operative extension bracing

Extensor mechanism complications after or during total knee arthroplasty (TKA) are problematic. The prevalence ranges from 1%-12% in TKA patients. Treatment results for these problems are inferior to the results of similar problems in non-TKA patients. Furthermore, the treatment algorithm is fundamentally different from that of non-TKA patients. The surgeon's first question does not focus on primary fixation; rather the surgeon must ask if the patient needs surgery and if so am I prepared to augment the repair? Quadriceps tendon rupture, peri-prosthetic patellar fracture, and patellar tendon rupture have similar treatment algorithms. Patients who are able to perform a straight leg raise and have less than a 20-degree extensor lag are generally treated non-operatively with extension bracing. The remaining patients will need surgical reconstruction of the extensor mechanism. Loose patellar components are removed. Primary repair alone is associated with poor results. Whole extensor mechanism allograft, Achilles tendon allograft, and synthetic mesh reconstruction are the current techniques for augmentation. In the acute setting if these are not available, hamstring tendon harvest and augmentation is an option. Achilles tendons and synthetic mesh are easier to obtain than an entire extensor mechanism but are limited to patients that have an intact patella and the patella that can be mobilised to within 2–3 cm of the joint line. No matter which technique is used the principles are: rigid distal/tubercle fixation, coverage of allograft/mesh with host tissue to decrease infection, tensioning the augment material in extension, no flexion testing of reconstruction and post-operative extension bracing

With cementless porous-coated acetabular replacements, extensive bone loss can occur without effecting implant stability. As a result, the surgeon is frequently faced with re-operating on a well-fixed cementless acetabular component with osteolysis and must decide whether or not to remove a well-fixed porous coated socket. A classification system and treatment algorithm has been developed to aid in management decisions regarding re-operation for polyethylene wear and pelvic osteolysis. Cases are classified into one of 3 possible categories depending on the radiographic stability of the porous coated shell and the ability to replace the polyethylene liner. Type I case; stable porous coated shell, liner replaceable; Type II case; socket stable, liner not replaceable;. Type III case; socket loose, not osseointegrated. Treatment Algorithms - Retain well-fixed shell in Type I cases and replace the liner. Debride accessible lytic lesions and graft with allograft chips. Remove the well-fixed shell in Type II case. Assess defect once the shell is removed. Reconstruction based on the bony defect present. The vast majority can be revised with a larger porous coated socket. Remove loose socket in Type III cases. Assess defect and reconstruct based on the defect. There is a greater need for more extensive grafting and the use of reconstruction rings with Type III cases. This treatment algorithm has helped the authors successfully evaluate and treat a large series of patients with polyethylene wear and pelvic osteolysis in association with porous coated acetabular components. The stability of the acetabular component and appropriate knowledge of the implant are important factors that impact surgical management

The Exeter stem is a polished cemented stem that has been associated with an excellent survivorship. However, this wedge shaped stem has also been associated with a relative higher risk for a peri-periprosthetic fracture due to the wedge-shaped configuration that can lead to a Vancouver type B2 fracture when the stem is being driven downwards inside the femoral canal by a traumatic blast. Traditionally, these fractures should be treated with a revision stem because the stem has become loosened in the fractured cement mantle. We present a case series of 5 cases where our treatment algorithm was to first let the non-displaced fracture to consolidate by 6 weeks of limited weight bearing as tolerated in order to conduct a second stage in-cement revision. This would simplify the revision procedure dramatically. However, all patients are currently pain free and do not require revision surgery although they are being monitored very closely. We conclude that non-displaced Vancouver type B2 fractures can be approached by a 2 stage treatment algorithm where the initial step is to let the fracture consolidate with limited weight bearing

Aim. Treatment of infected and non-infected non-unions remain a major challenge after orthopedic fracture-related surgery. In clinical practice, several revision surgeries are usually required, including a radical debridement and exchange of implants, to control or even eradicate the infection to finally achieve bone healing. However, a clear treatment algorithm in clinical practice may be difficult to follow due to the heterogeneous patient population. Thus, so controlled settings for research purposes is better achieved in standardized animal studies. So far, there exists no multi-stage animal model that can be realistically transferred to the clinical situation in humans. The importance of such a model is obvious in order to be able to investigate different therapy concepts for infected and non-infected non unions. Methods. In 20 female Sprague-Dawley rats, a critical size defect by a femur osteotomy with 5 mm width was done. The periosteum at the fracture zone was cauterized proximal and distal to the osteotomy to achieve an hypovascularized situation. After randomization, 10 animals were intramedullary infected with a multisensible Staph. aureus strain (10. 3. CFU). After 5 weeks, a second surgery was performed with removing the K-wire, debridement of the osteotomy-gap and re-osteosynthesis with an angle-stable plate. After further 8 weeks all rats were euthanized and underwent biomechanical testing to evaluate bone consolidation or delayed union, respectively. Additional micro-CT analysis, histological, and histomorphometric analysis were done to evaluate bone consolidation or delayed union, respectively, by the score of Lane and Sandhu and to quantify callus formation and the mineralized area of the callus. Results. 5 weeks after the first surgery a non-union had formed in all septic and aseptic animals. According to the Lane and Sandhu score a significantly higher callus formation was found in the infected group. In all infected animals, the inoculated Staph. aureus strain was detected during the revision surgery. 8 weeks after the second surgery no bone healing could be detected in the µ-CT analysis in both groups and biomechanical testing showed a significant lower maximum torque in both groups as compared to the untreated contralateral femura. Conclusion. Here we show first results of a new two-stage pseudarthrosis animal model, which reflects a very realistic clinical situation of an infection-related non-union model. Based on this model, various therapeutic strategies in the treatment of infectious and non-infectious pseudarthrosis, such as the use of bone substitutes, can be evaluated in further studies