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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 8 - 8
1 Jul 2012
Smith J Hannant GM London NJ
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This study was performed to evaluate the results of transphyseal anterior cruciate ligament (ACL) reconstruction in children with open physes. Between 2001 and 2009, 31 knees in 29 patients with a mean age of 14.1 years (10-16) underwent transphyseal, arthroscopic ACL reconstruction using an autogenous four-strand hamstrings graft. The technique was identical to that used in the adult population in our unit, except that care was taken to ensure fixation did not cross the physes. The patients were followed up to the point of physeal closure at skeletal maturity. The mean length of follow up was 25 months. The primary outcome measure was graft survival. Functional outcome was measured using Lysolm scores, International Knee Documentation Committee (IKDC) scores and the Tegner activity scale. Post-operative clinical examination and radiological findings were also recorded. There were two cases of re-rupture following a further sports injury, one 12 months post-operative and one at six years. Both patients later had successful revision ACL reconstructive surgery. The re-rupture rate in this case series was 6%. Two patients underwent repair of a concomitant lateral meniscal tear at the time of surgery. The mean post-operative Lysolm score was 88 and the mean IKDC score was 88.1. The mean Tegner activity scale was 7.95. There was no evidence of growth disturbance radiologically or leg length inequality clinically. There was one case of deep infection which was successfully treated with two subsequent arthroscopic washouts. This study demonstrates that transphyseal arthroscopic ACL reconstruction using hamstrings graft and an ‘adult’ technique, in skeletally immature patients, provides good functional outcomes, has a low revision rate and is not associated with physeal growth arrest or disturbance


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 59 - 59
1 Mar 2012
Gallacher P Gilbert R Carrothers A Kanes G Roberts S Rees D Jones R Hunt A
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Hypothesis. Avascular meniscal tears can be repaired with good clinical outcomes. Background. The mechanical disadvantage and detrimental effect to articular cartilage following meniscectomy has been well documented in the literature. Meniscal repair in the avascular (white on white zone) is controversial and would be deemed inappropriate by many. Methods. Between 1999 and 2008 our department prospectively collected data on all meniscal repairs as part of a sports injury database. 423 patients underwent meniscal repair at our unit during this time period. We identified 88 patients who underwent a meniscal repair of a non peripheral tear (white on white zone) where there was no co-existent ACL injury or instability. There were 74 males and 14 females with a mean age of 26 years (13-54). There were 50 medial meniscal tears and 38 lateral tears, all in the non peripheral area of the meniscus. The criterion for failure was any reoperation on the same meniscus requiring excision or re fixation. Results. The mean follow up was 44 months (5–106). Twenty nine patients required further surgery on their repaired meniscus. There were nine re-repairs and twenty partial menisectomies. Of the nine re-repairs only one has gone on to have a further procedure with meniscectomy. This represents a success rate of 67% (59/88). The mean pre-operative Lysholm score was 61 (4-88) which rose to 75 (12-100) postoperatively, (p=0.002). The mean pre-operative Tegner score was 6 (3-10) and this did not change significantly post operatively, mean 6 (0-10) (p=0.4). Conclusions. Isolated white on white avascular meniscal tears can be successfully repaired in the majority of cases with a good clinical and functional result


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 58 - 58
1 Mar 2012
Carmont M Ennis O Rees D
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We reviewed professional sportsmen who had undertaken Anterior Cruciate Ligament reconstruction to determine their actual and perceived sporting performance and long term outcome. The specific aim was to determine whether the players returned to the same standard of play, following reconstructive surgery. After IRAS approval, a questionnaire survey was distributed to 55 professional players on the Sports Injury Surgery ACL database. 24players returned questionnaires (response rate of 43.6%). Dates of surgery ranged from January 1998-February 2006. The mean elapsed time following surgery was 48 months (range 13-120 months). 12 patients had injured their left knee, 8 their right and 4 both knees. The respondents played rugby league 37% (9), soccer 33.3% (8), rugby union 21% (5) and netball 8.3% (2). 12 respondents were playing in the top leagues in their sports. 15 were regular first team players and 6 were squad players. 62.5% (15) thought they had returned to their previous standard of play, 29% (7) said that they had not and 2 did not know. 71% (17) of respondents thoughts their knee returned to normal however 25% (6) did not. The mean time for RTP was 10 months (5-21 months). Those that returned to the same standard were younger (21yrs) compared to those who did not (25yrs) (P=0.108). 4 players had torn the ACL in the opposite knee or ruptured their reconstruction. Additional meniscal injuries did not influence outcome and at 4 years most players had no or only slight symptoms with sport or activities of daily living. The rupture of the ACL is no longer a career ending injury for the professional sportsman. The majority (62.5%) of players will return to their pre-injury standard of play following reconstruction. The age at injury and additional meniscal injuries were not shown to be significant factors in this series


Aims

Proliferation, migration, and differentiation of anterior cruciate ligament (ACL) remnant and surrounding cells are fundamental processes for ACL reconstruction; however, the interaction between ACL remnant and surrounding cells is unclear. We hypothesized that ACL remnant cells preserve the capability to regulate the surrounding cells’ activity, collagen gene expression, and tenogenic differentiation. Moreover, extracorporeal shock wave (ESW) would not only promote activity of ACL remnant cells, but also enhance their paracrine regulation of surrounding cells.

Methods

Cell viability, proliferation, migration, and expression levels of Collagen-I (COL-I) A1, transforming growth factor beta (TGF-β), and vascular endothelial growth factor (VEGF) were compared between ACL remnant cells untreated and treated with ESW (0.15 mJ/mm2, 1,000 impulses, 4 Hz). To evaluate the subsequent effects on the surrounding cells, bone marrow stromal cells (BMSCs)’ viability, proliferation, migration, and levels of Type I Collagen, Type III Collagen, and tenogenic gene (Scx, TNC) expression were investigated using coculture system.


The Bone & Joint Journal
Vol. 101-B, Issue 9 | Pages 1058 - 1062
1 Sep 2019
van Kuijk KSR Reijman M Bierma-Zeinstra SMA Waarsing JH Meuffels DE

Aims

Little is known about the risk factors that predispose to a rupture of the posterior cruciate ligament (PCL). Identifying risk factors is the first step in trying to prevent a rupture of the PCL from occurring. The morphology of the knee in patients who rupture their PCL may differ from that of control patients. The purpose of this study was to identify any variations in bone morphology that are related to a PCL.

Patients and Methods

We compared the anteroposterior (AP), lateral, and Rosenberg view radiographs of 94 patients with a ruptured PCL to a control group of 168 patients matched by age, sex, and body mass index (BMI), but with an intact PCL after a knee injury. Statistical shape modelling software was used to assess the shape of the knee and determine any difference in anatomical landmarks.


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 9 | Pages 1216 - 1220
1 Sep 2012
Weston-Simons JS Pandit H Jenkins C Jackson WFM Price AJ Gill HS Dodd CAF Murray DW

The Oxford unicompartmental knee replacement (UKR) is an established treatment option in the management of symptomatic end-stage medial compartmental osteoarthritis (MCOA), which works well in the young and active patient. However, previous studies have shown that it is reliable only in the presence of a functionally intact anterior cruciate ligament (ACL). This review reports the outcomes, at a mean of five years and a maximum of ten years, of 52 consecutive patients with a mean age of 51 years (36 to 57) who underwent staged or simultaneous ACL reconstruction and Oxford UKR. At the last follow-up (with one patient lost to follow-up), the mean Oxford knee score was 41 (sd 6.3; 17 to 48). Two patients required conversion to TKR: one for progression of lateral compartment osteoarthritis and one for infection. Implant survival at five years was 93% (95% CI 83 to 100). All but one patient reported being satisfied with the procedure. The outcome was not significantly influenced by age, gender, femoral or tibial tunnel placement, or whether the procedure was undertaken at one- or two-stages.

In summary, ACL reconstruction and Oxford UKR gives good results in patients with end-stage MCOA secondary to ACL deficiency.


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 7 | Pages 949 - 953
1 Jul 2010
Narvani A Mahmud T Lavelle J Williams A

Most injuries to the medial collateral ligament (MCL) heal well after conservative treatment. We have identified a subgroup of injuries to the deep portion of the MCL which is refractory to conservative treatment and causes persistant symptoms. They usually occur in high-level football players and may require surgical repair.

We describe a consecutive series of 17 men with a mean age of 29 years (18 to 44) who were all engaged in high levels of sport. Following a minor injury to the MCL there was persistent tenderness at the site of the proximal attachment of the deep MCL. It could be precipitated by rapid external rotation at the knee by clinical testing or during sport. The mean time from injury to presentation was 23.6 weeks (10 to 79) and none of the patients had responded to conservative treatment. The surgical finding was a failure of healing of a tear of the deep MCL at its femoral origin which could be repaired. After a period of postoperative protective bracing and subsequent rehabilitation the outcome was good. All the patients returned to their sports and remained asymptomatic at a mean of 48 weeks (28 to 60) post-operatively.

Recognition of this subgroup is important since the clinical features, the course of recovery and surgical requirement differ from those of most injuries to the MCL.


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 3 | Pages 362 - 366
1 Mar 2010
Kennedy J Jackson MP O’Kelly P Moran R

We reviewed a single-surgeon series of 300 athletic patients who had undergone reconstruction of the anterior cruciate ligament in order to establish the relationship between the timing of the reconstruction and the incidence of meniscal and chondral pathology. The patients were divided into five groups according to the time from their injury to surgery as follows: less than two months, two to six months, six to 12 months, 12 to 18 months and more than 18 months. The presence of meniscal tears was recorded and chondral pathology was scored according to the system of the French Society of Arthroscopy.

There was a significantly higher chance of a medial meniscal tear occurring in patients undergoing reconstruction after one year from their injury (odds ratio (7.99, p = 0.004). The odds of having a lateral meniscal tear did not change significantly with an increasing interval to reconstruction. The chance of patients developing degenerative changes was found to be significantly higher in the groups operated on after six months from injury (odds ratio 4.04, p = 0.005).

We advocate that patients with deficiency of the anterior cruciate ligament should be counselled that there is a significant relationship between the duration of the instability of their knee and the subsequent incidence of both chondral changes and meniscal tears. In order to minimise these risks, we recommend that reconstruction be performed within the first year from injury.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 7 | Pages 893 - 899
1 Jul 2006
Petrou G Chardouvelis C Kouzoupis A Dermon A Petrou H Tilkeridis C Gavras M

We carried out a prospective study of 71 patients who had undergone reconstruction of the anterior cruciate ligament with the ABC scaffold. Their mean age was 28 years (18 to 50). All had either sub-acute or chronic traumatic deficiency of the ligament. The mean period of follow-up was five years (four to seven). Assessment included the use of the International Knee Documentation Committee score, the modified Lysholm score, the Tegner Activity score, the Knee Injury and Osteoarthritis Outcome score and measurement with the KT-1000 arthrometer. Two patients had mild recurrent synovitis. There were no infections and no failures of the ligament. During the period of study, two patients sustained a traumatic fracture of a femoral condyle. The implants retained their integrity in both cases. All patients returned to their previous or enhanced levels of daily activity by three months after operation and 56 (79%) achieved their pre-injury level of sporting activity by six months. The patients who were competing in National level sports returned to play at one level less after operation than before. The Lysholm score showed that 58% of the patients (41) were excellent, 34% (24) good, and 8% (6) fair, with a mean post-operative score of 93. According to the International Knee Documentation Committee score, 35% of knees (25) were ‘normal’, 52% (37) ‘nearly normal’ and 13% (9) ‘abnormal’. Complete satisfaction was noted in 90% of patients (64). The development of osteoarthritis and the management of anterior cruciate deficiency associated with laxity of the medial collateral ligament remains uncertain. Our results indicate that in the medium-term, the ABC ligament scaffold is suitable and effective when early and safe return to unrestricted activities is demanded. We acknowledge the current general hostility towards reconstruction of the anterior cruciate ligament with artificial materials following reports of early failure and chronic synovitis associatiated with the production of particulate debris. We did not encounter these problems.