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The Bone & Joint Journal
Vol. 106-B, Issue 10 | Pages 1067 - 1073
1 Oct 2024
Lodge CJ Adlan A Nandra RS Kaur J Jeys L Stevenson JD

Aims

Periprosthetic joint infection (PJI) is a challenging complication of any arthroplasty procedure. We reviewed our use of static antibiotic-loaded cement spacers (ABLCSs) for staged management of PJI where segmental bone loss, ligamentous instability, or soft-tissue defects necessitate a static construct. We reviewed factors contributing to their failure and techniques to avoid these complications when using ABLCSs in this context.

Methods

A retrospective analysis was conducted of 94 patients undergoing first-stage revision of an infected knee prosthesis between September 2007 and January 2020 at a single institution. Radiographs and clinical records were used to assess and classify the incidence and causes of static spacer failure. Of the 94 cases, there were 19 primary total knee arthroplasties (TKAs), ten revision TKAs (varus-valgus constraint), 20 hinged TKAs, one arthrodesis (nail), one failed spacer (performed elsewhere), 21 distal femoral endoprosthetic arthroplasties, and 22 proximal tibial arthroplasties.


The Bone & Joint Journal
Vol. 102-B, Issue 6 Supple A | Pages 91 - 95
1 Jun 2020
Johnson, Jr. WB Engh, Jr. CA Parks NL Hamilton WG Ho PH Fricka KB

Aims

It has been hypothesized that a unicompartmental knee arthroplasty (UKA) is more likely to be revised than a total knee arthroplasty (TKA) because conversion surgery to a primary TKA is a less complicated procedure. The purpose of this study was to determine if there is a lower threshold for revising a UKA compared with TKA based on Oxford Knee Scores (OKSs) and range of movement (ROM) at the time of revision.

Methods

We retrospectively reviewed 619 aseptic revision cases performed between December 1998 and October 2018. This included 138 UKAs that underwent conversion to TKA and 481 initial TKA revisions. Age, body mass index (BMI), time in situ, OKS, and ROM were available for all patients.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 52 - 52
1 Mar 2012
Youssef B Revell M McBryde C Pynsent P
Full Access

Aim

To assess the survival of revision knee replacements at our institution and to identify prognostic factors that predict failure in revision knee surgery.

Materials and methods

This was a retrospective review of 52 patients who had undergone revision knee surgery as identified by hospital clinical coding. Patient demographics, physiological parameters, reason for revision, type of revision implant and last date of follow up were recorded from the medical records. Implant survival was analysed both from the index primary procedure to revision and from definitive reconstruction at revision to re-operation for any cause.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 68 - 68
1 Mar 2012
Higgins G Kuzyk P Olsen M Waddell J Schemitsch E
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The aim of this study was to determine the mid-term survival and functional outcomes of the Scorpio Total Stabilised Revision Knee prosthesis.

Sixty seven prostheses were implanted between November 2001 and April 2008. 42 females and 23 males. Average patient age was 67.9 (37-89). Outcomes were assessed with WOMAC (Western Ontario and McMaster Universities Osteoarthritis index), Knee Society Scores, Short Form-8 scores, patient satisfaction and radiological review. Average follow-up was over 3 years (8-93mths) with 95% follow-up.

One patient died post operatively and 4 patients from 18 months to 5 years post-operatively. Average body mass index was 32.9 (21.5- 55.1). 65% (42 patients) of patients operated on had a Body Mass Index of greater than 30. 48 patients were ASA 3 or greater.

Thirteen second stage revision arthroplasties were performed after treatment for infected arthroplasty surgery. Twenty six prostheses were revised for aseptic loosening. Eight prostheses were revised for stiffness and 9 for worn polyethylene inserts. Five prostheses were revised for symptomatic tibio-femoral instability/ dislocation and one for patello-femoral instability. Two revisions were performed for peri-prosthetic fractures and 2 for previously operated tibial plateau fractures.

Seven patients required tibial tubercle osteotomy and seven a rectus snip. Thirty one patients had greater than a 15mm polyethylene insert. The average KSS increased from 49 pre-operatively to 64 at 7.5 years. The average KS function score increased from 21 to 45. 68% (44) of patients had other significant joint involvement which affected daily function. 24% of patients were unsatisfied with the outcome. 89.5% of patients radiographs were assessed for loosening or subsidence. 51% of femoral components and 36% of tibial components had radiosclerotic lines. The surface area of each implant including the stem was measured on antero-posterior and lateral images. The degree of lucency was calculated as a percentage and in mm from the component.

Two prostheses (3%) were revised for deep infection, one (1.5%) for stiffness and one for aseptic loosening (1.5%). Complications included a popliteal artery injury, two superficial wound infections, and one patella tendon avulsion.

Survival rate for revision of prosthesis was 87% at 7.5 years and 90% excluding infection. Success of second stage revision arthroplasty after treatment of infection was 92%.


Bone & Joint Open
Vol. 2, Issue 8 | Pages 638 - 645
1 Aug 2021
Garner AJ Edwards TC Liddle AD Jones GG Cobb JP

Aims. Joint registries classify all further arthroplasty procedures to a knee with an existing partial arthroplasty as revision surgery, regardless of the actual procedure performed. Relatively minor procedures, including bearing exchanges, are classified in the same way as major operations requiring augments and stems. A new classification system is proposed to acknowledge and describe the detail of these procedures, which has implications for risk, recovery, and health economics. Methods. Classification categories were proposed by a surgical consensus group, then ranked by patients, according to perceived invasiveness and implications for recovery. In round one, 26 revision cases were classified by the consensus group. Results were tested for inter-rater reliability. In round two, four additional cases were added for clarity. Round three repeated the survey one month later, subject to inter- and intrarater reliability testing. In round four, five additional expert partial knee arthroplasty surgeons were asked to classify the 30 cases according to the proposed revision partial knee classification (RPKC) system. Results. Four classes were proposed: PR1, where no bone-implant interfaces are affected; PR2, where surgery does not include conversion to total knee arthroplasty, for example, a second partial arthroplasty to a native compartment; PR3, when a standard primary total knee prosthesis is used; and PR4 when revision components are necessary. Round one resulted in 92% inter-rater agreement (Kendall’s W 0.97; p < 0.005), rising to 93% in round two (Kendall’s W 0.98; p < 0.001). Round three demonstrated 97% agreement (Kendall’s W 0.98; p < 0.001), with high intra-rater reliability (interclass correlation coefficient (ICC) 0.99; 95% confidence interval 0.98 to 0.99). Round four resulted in 80% agreement (Kendall’s W 0.92; p < 0.001). Conclusion. The RPKC system accounts for all procedures which may be appropriate following partial knee arthroplasty. It has been shown to be reliable, repeatable and pragmatic. The implications for patient care and health economics are discussed. Cite this article: Bone Jt Open 2021;2(8):638–645


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 26 - 26
1 Oct 2019
Dalury DF Chapman DM Miller MJ
Full Access

Introduction. Enhanced pain and rehabilitation protocols have significantly improved patient recovery following primary TKR. Little has been written on how the protocols have affected the revision TKR patient. We report on a matched group of revision and primary TKR patients treated with the identical pain and rehab program. Materials and Methods. 40 aseptic RTKR patients who underwent a full femoral and tibial revision were matched by age, sex, and BMI to a group of patients who underwent a cemented tri-compartmental primary TKR. All revision knees had uncemented stemmed femurs and tibias. All 40 patients had either a metaphyseal sleeve on either the femur or tibia or both. Patients in both groups were treated with an identical post op pain protocol (Spinal anesthetic, local infiltrative analgesia and multimodal oral pain management along with rapid rehabilitation). All patients were mobilized on POD1 and allowed weight bearing as tolerated. Patients were followed for a minimum of 1 year. KSS at 6 weeks and 1 year were recorded for both groups. Results. There was no significant difference in length of stay between the RTKR and the primary TKR (1.2 days versus 1.1 days). Average oral morphine equivalents used during the hospitalization was 38 for the RTKR and 42 for the primary group. There was 1 readmission in each group: GI distress in the RTKR and urinary retention in the primary group. There no were reoperations, wound healing problems, identified thromboembolic events or manipulations under anesthesia in either group. KSS for the RTKR group averaged 87.3 at 6 weeks (range 45 to 99) and 89.1at minimum 1 year (range 52 to100). KSS for the primary group averaged 89.9 (range 71 to 100) at 6 week follow-up and 93.2 (range 54 to 100) at minimum follow-up. Range of motion at final follow up averaged1.2 (0–10) to 114.1 (55–135) for the RTKR group and 1 (0–8) to 121.3 (85–140) for the primary group. Conclusion. Despite more complex surgery in the revision total knee patient, enhanced pain and rehabilitation protocols have enabled the RTKR patient to have a similar recovery and outcome compared to the primary TKR patient. For figures, tables, or references, please contact authors directly


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_9 | Pages 52 - 52
1 Oct 2020
Dalury DF Chapman DM
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Introduction. One of the main considerations in the revision TKR setting is deciding on the level of constraint to be utilized once the bone defects have been reconstructed. There is a fear that employing a maximally constrained insert could compromise long term results. We report on a consecutive series of full tibial and femoral component revisions all treated with a maximally conforming insert and followed for a minimum of 5 years. Materials and Methods. The study group consisted of 76 consecutive revision TKR in 76 patients where both the femur and the tibia were revised. 4 patients died and 6 were lost to follow up. Final cohort had an average age of 70 years, average BMI of 31 and there were 39 males in the group. Average time to revision was 7 years (range 1–10 years) and the reasons for revision included infection in 28, aseptic loosening 26, osteolysis and poly wear in 9 and 13 other. All were treated with the same revision system and an identical maximally conforming tibial rotating platform insert and followed for an average of 7 years (range 5–14 years). Results. one patient required additional surgery during the study period for a patella fracture. There were no manipulations. Average Knee Society Scores increased from an average of 55 to 89 at final follow up. No implants were loose or at risk of loosening and no knee sustained any mechanical complications related to the insert. Conclusion. Despite fears to the contrary, we did not identify any issues in using a maximally constrained insert in this consecutive group of revision total knee patients. It is unclear if the fact that these inserts were of a rotating platform design is important. In this group of revision TKRs, using the maximal level of constraint did not appear to negatively influence outcome at mid-term follow up


The Bone & Joint Journal
Vol. 101-B, Issue 6 | Pages 675 - 681
1 Jun 2019
Gabor JA Padilla JA Feng JE Anoushiravani AA Slover J Schwarzkopf R

Aims

Revision total knee arthroplasty (rTKA) accounts for approximately 5% to 10% of all TKAs. Although the complexity of these procedures is well recognized, few investigators have evaluated the cost and value-added with the implementation of a dedicated revision arthroplasty service. The aim of the present study is to compare and contrast surgeon productivity in several differing models of activity.

Materials and Methods

All patients that underwent primary or revision TKA from January 2016 to June 2018 were included as the primary source of data. All rTKA patients were categorized by the number of components revised (e.g. liner exchange, two or more components). Three models were used to assess the potential surgical productivity of a dedicated rTKA service : 1) work relative value unit (RVU) versus mean surgical time; 2) primary TKA with a single operating theatre (OT) versus rTKA with a single OT; and 3) primary TKA with two OTs versus rTKA with a single OT.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 29 - 29
1 Oct 2019
Tetreault MW Perry KI Pagnano MW Hanssen AD Abdel MP
Full Access

Introduction

Metaphyseal fixation during revision total knee arthroplasties (TKAs) is important, but potentially challenging with historical cone designs. Material and manufacturing innovations have improved the size and shape of cones available, and simplified requisite bone preparation. In a very large series, we assessed implant survivorship, radiographic results, and clinical outcomes of new porous 3-D printed titanium metaphyseal cones featuring a reamer-based system.

Methods

We reviewed 142 revision TKAs using 202 cones (134 tibial and 68 femoral) from 2015 to 2016. Sixty cases involved tibial and femoral cones. Most cones (149 of 202; 74%) were used for Type 2B or 3 bone loss. Mean age was 66 years, with 54 % females. Mean BMI was 34 kg/m2. Patients had a mean of 2.4 prior surgeries and 48% had a history of periprosthetic infection. Mean follow-up was 2 years.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 30 - 30
1 Oct 2019
Bedard NA Cates RA Lewallen DG Hanssen AD Berry DJ Abdel MP
Full Access

Introduction

Metaphyseal cones with cemented stems are frequently used in revision total knee arthroplasties (TKAs). However, if the diaphysis has been previously violated (as in revision of a failed stemmed implant), the resultant sclerotic canal can impair cemented stem fixation, which is vital for cone ingrowth and long-term fixation. We report the outcomes of our novel solution to this problem, in which impaction grafting and a cemented stem in the diaphysis was combined with an uncemented metaphyseal cone for revision TKAs with severely compromised bone.

Methods

A metaphyseal cone was combined with diaphyseal impaction grafting and cemented stems in a novel fashion for 35 revision TKAs. Mean age at revision TKA was 70 years, with 63% being male. Patients had a mean of 4 prior knee arthroplasty procedures. Indications for the revision with this construct were aseptic loosening (80%) and two-stage re-implantation for periprosthetic infection (PJI; 20%). Mean follow-up was 3 years.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 51 - 51
1 Mar 2012
Hay-David A McConnell JS Bhinda H A AG
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We studied a series of Endo-Modell(r) rotating hinge knee replacements (RHKRs) to determine indications, implant survival and complication rates.

Case notes were audited for a consecutive series of 129 implants performed between 08/12/2002 and 30/01/2009.

Indication for use of RHKR was complex primary arthroplasty in 37.8% and revision in 62.2%.

For primary arthroplasty with hinge prosthesis, commonest indications were: collateral ligament insufficiency (44.4%); advanced RA (13.9%); supracondylar fracture (5.6%). Indications for revision RHK arthroplasty were: aseptic loosening (40.4%); ligamentous or soft tissue failure (14.0%); periprosthetic fracture (7%); infection (51%). Infection was proven in 21% with 54% of patients requiring a one stage and 46% two stage revision. For revision cases, 74% of primary prostheses were cruciate retaining PFC (Depuy) and in 5%, the primary was itself an Endo-Modell(r) RHKR.

Mean time from index to revision procedures was 6.7 years (range 1 year – 23 years).

Complications were: deep infection (6.1%) and non-fatal PE (1%). None developed clinically detectable DVT. Transfusion was required in 29 cases (for such cases, an average 3 units was given). 30-day mortality was 1%. For the revision cases, the average length of hospital admission was 11 days.

Mean duration of follow up was 45 months (with a minimum of 21 days and maximum of 92 months). During this time 2 RHKRs failed. A total of 7 patients died during the period from complications unrelated to their surgery. 31 cases were lost to follow up.

We conclude that in this series of Endo-Modell(r) rotating hinge knee arthroplasties, results are comparable with similar revision procedures. There was a low rate of prosthesis failure, DVT and PE.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_13 | Pages 47 - 47
7 Aug 2023
Reason L Jonas S Evans JT Eyres KS Toms AD Kalson NS Phillips JR
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Abstract. Introduction. Choosing a hinged implant in the revision knee arthroplasty (rTKA) setting is challenging and limited data on implant performance exists. We present the survivorship and reason for failure in rTKA performed at our institution using the LINK hinge prosthesis, predominantly the cemented modular Endo-Model prosthesis. Methodology. 260 consecutive revision knee cases performed between 2012 and 2020 were reviewed retrospectively. Mean follow up was 27 months (range 0 to 107). Survivorship was analysed in Stata using a Log Rank test to compare performance in patients stratified according to age (≥80 years old (76 cases), 70–79 years (104 cases) and ≤70 years (80 cases). Results. 53 patients died and 48/207 (23%) cases in 40 patients underwent re-revision. Reasons for re-revision were aseptic loosening (21), infection (12), instability (4), extensor failure (1), stiffness (1), fracture (1) and other (8). Loosening was seen in the femur (8), tibia (5), and both the femur and tibia (8). Sub-group analysis of patients according to age showed a significantly higher failure rate in younger patients (6 failures (8%) in patients ≥80, 27 failures (26%) in 70–79 and 15 (19%) in ≤70 (p = 0.02). Failure in patients ≤70 was predominantly due to aseptic loosening (8/15). Conclusion. Here we report a significantly higher rate of LINK hinge prostheses failure in patients <70 undergoing rTKA. Consent should consider the risk of re-revision in this patient group


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 63 - 63
1 Jul 2022
Sabah S Fritsch LV Price A Alvand A
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Abstract. Introduction. A revision knee replacement (rKR) network model has been introduced in the UK to improve clinical outcomes for patients and reduce healthcare costs. However, the current practice of different types of surgical unit is not well understood. The aim of this study was to answer: “How complex are rKR cases at a Major Revision Centre (MRC)?”. Methodology. Retrospective cohort study at the Nuffield Orthopaedic Centre, Oxford from 2015 - 2018. Case complexity was classified using the Revision Knee Complexity Classification (RKCC). Referral source, technical details of surgery and hospital admission impact were recorded. Results. 688 rKR procedures (380 rKR, 308 re-revision KR) were identified over the study period. 170 rKR (24.7%) were unplanned admissions requiring surgery, whilst the remaining cases were elective. 288/688 rKR (41.9%) were external referrals, where surgical complexity was rated ‘less complex’ (96 rKR, 33.3%), ‘more complex’ (92 rKR, 31.9%) and ‘most complex’ (100 rKR, 34.7%). 140/288 (48.6%) of these cases had one or more rKR prior to referral. Length of stay (LOS) was greater for more complex cases (R1 median 5 days [interquartile range 3–9], R2 median 9 days [IQR 5–15], R3 median 11 days [IQR 7–19]). Conclusion. rKR complexity at the MRC followed a ‘rule of thirds’. Among external referrals, nearly half of patients had a previous rKR prior to referral. More complex cases required longer hospital admissions


Bone & Joint Open
Vol. 4, Issue 10 | Pages 776 - 781
16 Oct 2023
Matar HE Bloch BV James PJ

Aims

The aim of this study was to evaluate medium- to long-term outcomes and complications of the Stanmore Modular Individualised Lower Extremity System (SMILES) rotating hinge implant in revision total knee arthroplasty (rTKA) at a tertiary unit. It is hypothesized that this fully cemented construct leads to satisfactory clinical outcomes.

Methods

A retrospective consecutive study of all patients who underwent a rTKA using the fully cemented SMILES rotating hinge prosthesis between 2005 to 2018. Outcome measures included aseptic loosening, reoperations, revision for any cause, complications, and survivorship. Patients and implant survivorship data were identified through both prospectively collected local hospital electronic databases and linked data from the National Joint Registry/NHS Personal Demographic Service. Kaplan-Meier survival analysis was used at ten years.


The Bone & Joint Journal
Vol. 105-B, Issue 1 | Pages 47 - 55
1 Jan 2023
Clement ND Avery P Mason J Baker PN Deehan DJ

Aims

The aim of this study was to identify variables associated with time to revision, demographic details associated with revision indication, and type of prosthesis employed, and to describe the survival of hinge knee arthroplasty (HKA) when used for first-time knee revision surgery and factors that were associated with re-revision.

Methods

Patient demographic details, BMI, American Society of Anesthesiologists (ASA) grade, indication for revision, surgical approach, surgeon grade, implant type (fixed and rotating), time of revision from primary implantation, and re-revision if undertaken were obtained from the National Joint Registry data for England, Wales, Northern Ireland, and the Isle of Man over an 18-year period (2003 to 2021).


Bone & Joint Open
Vol. 4, Issue 12 | Pages 948 - 956
15 Dec 2023
Vella-Baldacchino M Webb J Selvarajah B Chatha S Davies A Cobb JP Liddle AD

Aims

With up to 40% of patients having patellofemoral joint osteoarthritis (PFJ OA), the two arthroplasty options are to replace solely the patellofemoral joint via patellofemoral arthroplasty (PFA), or the entire knee via total knee arthroplasty (TKA). The aim of this study was to assess postoperative success of second-generation PFAs compared to TKAs for patients treated for PFJ OA using patient-reported outcome measures (PROMs) and domains deemed important by patients following a patient and public involvement meeting.

Methods

MEDLINE, EMBASE via OVID, CINAHL, and EBSCO were searched from inception to January 2022. Any study addressing surgical treatment of primary patellofemoral joint OA using second generation PFA and TKA in patients aged above 18 years with follow-up data of 30 days were included. Studies relating to OA secondary to trauma were excluded. ROB-2 and ROBINS-I bias tools were used.


The Bone & Joint Journal
Vol. 104-B, Issue 3 | Pages 376 - 385
1 Mar 2022
Gramlich Y Hofmann L Kress S Ruckes C Kemmerer M Klug A Hoffmann R Kremer M

Aims

This study compared the cobalt and chromium serum ion concentration of patients treated with two different metal-on-metal (MoM) hinged total knee arthroplasty (TKA) systems, as well as a titanium nitride (TiN)-coated variant.

Methods

A total of 63 patients (65 implants) were treated using either a MoM-coated (n = 29) or TiN-coated (n = 7) hinged TKA (GenuX mobile bearing, MUTARS; Implantcast, Germany) versus the BPKS (Brehm, Germany) hinged TKA (n = 27), in which the weight placed on the MoM hinge is diffused through a polyethylene (PE) inlay, reducing the direct load on the MoM hinge. Serum cobalt and chromium ion concentrations were assessed after minimum follow-up of 12 months, as well as functional outcome and quality of life.


Bone & Joint Open
Vol. 3, Issue 2 | Pages 107 - 113
1 Feb 2022
Brunt ACC Gillespie M Holland G Brenkel I Walmsley P

Aims

Periprosthetic joint infection (PJI) occurs in approximately 1% to 2% of total knee arthroplasties (TKA) presenting multiple challenges, such as difficulty in diagnosis, technical complexity, and financial costs. Two-stage exchange is the gold standard for treating PJI but emerging evidence suggests 'two-in-one' single-stage revision as an alternative, delivering comparable outcomes, reduced morbidity, and cost-effectiveness. This study investigates five-year results of modified single-stage revision for treatment of PJI following TKA with bone loss.

Methods

Patients were identified from prospective data on all TKA patients with PJI following the primary procedure. Inclusion criteria were: revision for PJI with bone loss requiring reconstruction, and a minimum five years’ follow-up. Patients were followed up for recurrent infection and assessment of function. Tools used to assess function were Oxford Knee Score (OKS) and American Knee Society Score (AKSS).


The Bone & Joint Journal
Vol. 104-B, Issue 1 | Pages 45 - 52
1 Jan 2022
Yapp LZ Clement ND Moran M Clarke JV Simpson AHRW Scott CEH

Aims

The aim of this study was to determine the long-term mortality rate, and to identify factors associated with this, following primary and revision knee arthroplasty (KA).

Methods

Data from the Scottish Arthroplasty Project (1998 to 2019) were retrospectively analyzed. Patient mortality data were linked from the National Records of Scotland. Analyses were performed separately for the primary and revised KA cohorts. The standardized mortality ratio (SMR) with 95% confidence intervals (CIs) was calculated for the population at risk. Multivariable Cox proportional hazards were used to identify predictors and estimate relative mortality risks.


The Bone & Joint Journal
Vol. 103-B, Issue 10 | Pages 1578 - 1585
1 Oct 2021
Abram SGF Sabah SA Alvand A Price AJ

Aims

To compare rates of serious adverse events in patients undergoing revision knee arthroplasty with consideration of the indication for revision (urgent versus elective indications), and compare these with primary arthroplasty and re-revision arthroplasty.

Methods

Patients undergoing primary knee arthroplasty were identified in the national Hospital Episode Statistics (HES) between 1 April 1997 to 31 March 2017. Subsequent revision and re-revision arthroplasty procedures in the same patients and same knee were identified. The primary outcome was 90-day mortality and a logistic regression model was used to investigate factors associated with 90-day mortality and secondary adverse outcomes, including infection (undergoing surgery), pulmonary embolism, myocardial infarction, and stroke. Urgent indications for revision arthroplasty were defined as infection or fracture, and all other indications (e.g. loosening, instability, wear) were included in the elective indications cohort.