Aims. The most important complication of treatment of developmental dysplasia of the hip (DDH) is
Aims. The aim of this study was to compare outcomes of guided growth and varus osteotomy in treating Kalamchi type II
Introduction and Objective.
The cause of fracture of the femoral neck after hip resurfacing is poorly understood. In order to evaluate the role of
Introduction. The objective of the work is construction of a multi-bioactive scaffold based on that allows a space/time control over the regeneration of damaged bones by Medication-Related
Aims. The aim of this study was to clarify the factors that predict the development of
The use of bisphosphonates in the treatment of
Whereas
We performed 96 Birmingham resurfacing arthroplasties of the hip in 71 consecutive patients with
Aims.
Summary Statement.
Femoral head osteonecrosis (FHO) is a condition in which the inadequate blood supply disrupts osteogenic-angiogenic coupling that results in diminishment of femoral perfusion and ends up with FHO. The insufficient knowledge on molecular background and progression pattern of FHO and the restrictions in obtaining human samples bring out the need for a small animal trauma model to research FHO aetiology. Hence, this study aims to develop a mouse trauma model to elucidate the molecular mechanisms behind FHO. Left femoral head was dislocated from the hip joint, ligamentum teres was cut, and a slight circular incision was done around the femoral neck of 8-week-old male C57BL/6J mice to disrupt the blood supply to femoral head. Right hip joint was left unoperated as control. Animals (n=5 per time point) were sacrificed on 2-3-4-6-8-10-12 weeks, and ex-vivo µCT was taken to assess bone structural parameters. Haematoxylin/eosin (HE)- and immunohistochemical-staining (IHCS) for CD31 and EMCN were done to observe histology and marrow-specific H-type vascular structures, respectively.Introduction
Method
We investigated the incidence and risk factors
for the development of