In combined high median and ulnar nerve injury, transfer of extensor digiti minimi (EDM) and extensor carpi ulnaris (ECU) nerve branches to restore intrinsic hand function is previously described. A segment of nerve graft is required in this operation. The aim of this study was to evaluate the feasibility of using the sensory branch of radial nerve (SRN) as an “in situ vascular nerve bridge'” (IVNB) instead of sural nerve graft.

Twenty fresh cadavers were dissected. In proximal forearm incision, the feasibility of transferring the EDM/ECU branches to the distal stump of transected SRN was evaluated. In distal forearm incision, the two distal branches of the SRN were transected near the radial styloid process to determine whether transfer of the proximal stumps of these branches to the motor branches of the median (MMN) and ulnar (MUN) nerves is possible. The number of axons in each nerve was determined.

The size of the dissected nerves and their location demonstrate that tension free nerve coaptation is easily possible in both proximal and distal incisions.

Utilisation of the SRN as an IVNB instead of the conventional sural nerve graft has some advantages. Firstly, the sural nerve graft is a single branch and could be sutured to either the MMN or MUN, whereas the SRN has two terminal branches and can address both of them. Secondly, the IVNB has live Schwann cells and may accelerate the regeneration. Finally, this IVNB does not require leg incision and could be performed under regional anesthesia. The SRN as an IVNB is a viable option which can be used instead of conventional nerve graft in some brachial plexus or high median and ulnar nerve injuries when restoration of intrinsic hand function by transfer of EDM/ECU branches is attempted.

The ability to calculate quality-adjusted life-years (QALYs) for degenerative cervical myelopathy (DCM) would enhance treatment decision making and facilitate economic analysis. QALYs are calculated using utilities, or health-related quality-of-life (HRQoL) weights. An instrument designed for cervical myelopathy disease would increase the sensitivity and specificity of HRQoL assessments. The objective of this study is to develop a multi-attribute utility function for the modified Japanese Orthopedic Association (mJOA) Score. We recruited a sample of 760 adults from a market research panel. Using an online discrete choice experiment (DCE), participants rated 8 choice sets based on mJOA health states. A multi-attribute utility function was estimated using a mixed multinomial-logit regression model (MIXL). The sample was partitioned into a training set used for model fitting and validation set used for model evaluation. The regression model demonstrated good predictive performance on the validation set with an AUC of 0.81 (95% CI: 0.80-0.82)). The regression model was used to develop a utility scoring rubric for the mJOA. Regression results revealed that participants did not regard all mJOA domains as equally important. The rank order of importance was (in decreasing order): lower extremity motor function, upper extremity motor function, sphincter function, upper extremity sensation. This study provides a simple technique for converting the mJOA score to utilities and quantify the importance of mJOA domains. The ability to evaluate QALYs for DCM will facilitate economic analysis and patient counseling. Clinicians should use these findings in order to offer treatments that maximize function in the attributes viewed most important by patients

In Asia, traditional bands are placed around limbs of children to ward off evil spirits and ensure good health. This practice may lead to the Rubber Band Syndrome (RBS) a rare paediatric condition described mainly in Asia which results from a forgotten thread or elastic band applied to the limb of a child. Because pressure necrosis beneath the band is slow, rapid healing of tissues over the band can obscure its presence. This makes the condition difficult to diagnose and distinguish from other infective conditions. This study presents the first case of RBS reported in South Africa. Case: The patient aged 18 months presented with a swollen hand, circumferential scar and discharging sinus on the wrist. A radiograph was negative. In theatre the volar wound was explored. Debridement revealed a yellow rubber band deep to the wrist flexors and neurovascular bundles but superficial to the extensor retinaculum. Complete removal of the rubber band and antibiotics was followed by rehabilitation with Occupational Therapy. At a 3 month follow up, there was no evidence of infection, sensation was normal and motor function of the hand restored. In this case, the structures through which the band had already passed were intact and overlay the band. It would appear that as the band slowly eroded the underlying structures it was followed by healing along the tract until the band exited deep to these structures. The band may come to rest on bone causing osteomyelitis if allowed to progress. A high index of suspicion of RBS is needed in children presenting with a circumferential scar and a non-healing wound, especially on the wrist or ankle. Careful debridement and complete removal of the band are essential to resolve symptoms and restore function

Cerebral Palsy (CP) is a group of disorders that affect movement and posture caused by injury to the developing brain. While prematurity and low birth weight are common causes in developed countries, birth asphyxia, kernicterus, and infections have been identified as predominant aetiologies in Africa. There is, however, very little information on the aetiology of CP in South Africa. The purpose of this study was to determine the aetiology, severity, and topographical distribution of CP in children undergoing orthopaedic surgery at our tertiary paediatric unit. A retrospective folder review was performed for patients with CP that underwent orthopaedic surgery from July 2018 to June 2022. Data was collected on perinatal circumstances, aetiology or risk factors for developing CP, severity of disability as classified by the Gross Motor Function Classification Scale (GMFCS) and topographical distribution. Descriptive analysis was performed. Two-hundred-and-thirty-four patients were included in the analysis. No specific aetiology could be identified in 51 (21.9%) patients. Hypoxic ischaemic encephalopathy (HIE) accounted for 23.6% of patients and was the most common aetiology across the different categories except for patients graded as GMFCS 2, in whom prematurity was the most common aetiology. Congenital brain malformations (10.5%) and cerebral infections, including HIV encephalopathy (11.4%) were the next most frequent aetiologies, followed by prematurity (7.6%), ischaemic stroke (6.8%) and intraventricular haemorrhage (6.3%). Fifty-two percent of patients were classified as GMFCS 4 or 5. There was a predominance of quadriplegic patients (37%) compared to hemiplegics (29%), diplegics (30%) and monoplegics (4%). Most patients undergoing orthopaedic surgery for musculoskeletal sequelae of CP were severely disabled quadriplegic patients in whom HIE was the predominant cause of CP. This emphasises the need for intervention at a primary care level to decrease the incidence of this frequently preventable condition

Treatment for hip displacement in children and youth with cerebral palsy (CP) is dependent upon when the problem is detected. Hip surveillance aims to identify hip displacement early through systematic screening and, together with timely orthopaedic intervention, can eliminate the need for salvage hip procedures. Here we report the impact on surgical practice of 1) hip surveillance program advocacy and knowledge translation efforts and 2) initial population-based program implementation. A retrospective review was completed of all children with CP undergoing surgery for hip displacement at a provincial tertiary pediatric hospital in the years 2004 to 2018. Date and type of surgery, age at surgery, Gross Motor Function Classification System (GMFCS) level, and pre-operative migration percentages (MP) were collected. Surgeries were categorized as soft-tissue release, reconstructive, and salvage procedures. Results were collected for three time periods: historical (September 2004- June 2010), hip surveillance advocacy and knowledge translation (July 2010- August 2015), and post provincial hip surveillance program implementation (September 2015 – December 2018). A total of 261 surgeries on 321 hips were reviewed. The rate of salvage procedures dropped from 29% (24) of surgeries performed in the historical period to 12% (14) during the period that included targeted hip surveillance knowledge translation and development of provincial guidelines. Since implementation of the surveillance program, salvage procedures have accounted for 7% (4) of interventions performed; all of these were in patients new to the province or existing patients. During the three study periods, reconstructive surgeries accounted for 64%, 81%, and 80% of the interventions performed. The mean initial MP at time of reconstructive surgery has decreased from 66% (SD 20%) in the historical time period to 57% (SD 25%) and 57% (SD 22%) in the subsequent time periods. There were a greater number of children at GMFCS levels III and IV in the two more recent time periods suggesting surveillance may assist in identifying children at these levels of impairment. The rate of soft-tissue surgeries was low during all time periods with the number trending higher since program implementation (7%, 7%, 10%). Knowledge translation and use of standardized surveillance guidelines can have a significant impact on the prevalence of salvage hip surgeries. Centers should utilize existing surveillance guidelines and educate key stakeholders about the importance of hip surveillance in the absence of a formal hip surveillance program

Intramuscular injections of botulinum neuro toxin A (BoNT-A) have been a cornerstone in the treatment of spasticity for the last two decades. In India, the treatment is now offered to children with spastic cerebral palsy (CP). However, despite its use, the evidence for its functional effects is limited and inconclusive. The objective of this study is to determine whether BoNT-A makes walking easier in children with CP. We hypothesize that injections with BoNT-A will not reduce energy cost during walking, improve walking capacity, reduce pain or improve self-perceived performance and satisfaction. Between the period of 2012 and 2014, 35 children with spastic CP less than 10 years of age were included. The patients were classified according to their gross motor function classification system (GMFCS) and their pre-and post-injection gait analysis were performed. Spasticity assessed by Modified Ashworth Score [MAS]. Trained parents were utilised for the post injection physiotherapy as these children will be more complaint to them. GMFCS and MAS scoring done every three months till one year follow up. Therapeutically, effect was found in 90% of the patients, an average duration of the medical effect was 6–12 months. The improvement in GMFC functional score in serial measurements was seen in these patients though some deterioration in spasticity scores at one year. Despite mild recurrence in spasticity, majority maintained independent (42%) or assisted ambulation (48%) at one year. No major side effects occurred. Botox may prove a useful adjuvant in conservative management of the spasticity of cerebral palsy. Apart from being very cost effective in these financially deprived populations, successful management with these injections may allow delay of surgical intervention until the child is older and at less risk of possible complications, including the need for repeated surgical procedures

Clinical nerve injury has been reported in 0.6–4.8% of shoulder arthroplasties. Classical teaching is that 70–85% of injuries recover. Despite recovery of motor function, overall shoulder function may be negatively affected and residual pain is common. Complex regional pain syndromes may develop and become permanent. Consequently, methods to limit nerve injury have been investigated. In the early 2000's I became concerned about the incidence of nerve injuries in my arthroplasty practice. I became intrigued with the idea of peripheral nerve monitoring as a method to alert the surgeon intra-operatively about impending nerve insults so that evasive measures could be taken to prevent any clinically significant nerve injuries. The results of our first 30 consecutive patients were published in JSES in 2007. Seventeen patients (56.7%) had 30 episodes of nerve dysfunction (i.e. nerve alerts) during surgery. Twenty-three of thirty alerts (76.7%) returned to normal after repositioning the arm to a neutral position. Post-operative EMG was positive in 4 of 7 (57.1%) patients who did not have a return to normal motor latency intra-operatively and in 1 of 10 (10%) patients whose intra-operative nerve function did return to normal. None had clinical nerve injuries. This early experience indicated that nerve injury was potentially more common than previously thought but intra-operative nerve monitoring seemed to have a relatively high false positive rate. Our group subsequently studied 440 shoulder arthroplasty cases. The protocol used to identify a nerve alert was made more restrictive than the first study as an attempt to decrease the false positive rate. In this larger group, nerve alerts occurred in 185 cases (42.0%), and 37 (8.4%) cases did not have signals return to above the alert threshold at closure. There were no permanent post-operative nerve injuries and 5 transient nerve injuries (1.1%). Cases in which MEP amplitudes remained below alert threshold were significantly more likely to have a post-operative nerve injury (p = 0.03). There were no false negatives, (i.e. a post-operative nerve injury occurred while MEPs were normal at closure), making sensitivity 100%. There were 32 false positives, leading to a specificity of 92.6%, a positive predictive value (PPV) of 13.5%, a negative predictive value (NPV) of 100%, and an accuracy (ACC) of 92.3%. In my opinion, the high false positive rate and the low PPV make the technique difficult to justify for routine clinical use

Aim. In an earlier study we identified severe Vitamin D deficiency as a problem in institutionalised children with cerebral palsy (CP), which resulted in rickets and a high incidence of fractures. The purpose of this study was to establish whether a cohort of non-ambulatory children with CP, living at home, presented with Vitamin D deficiency. Method. The participants were a consecutive sample (N=100) of non-ambulatory children with CP attending a CP outpatient clinic. Their ages ranged from 2 to 15 years (mean 5.8, SD 3.3 years). There were 57 males and 43 females. Nineteen were on Level IV of the Gross Motor Function Classification System (GMFCS), and 81 were on Level V. 66% were on anticonvulsant therapy (ACT). Basic demographic data was collected, and measurements included blood sample analysis and wrist radiographs. There was radiographic evidence of osteopenia and delayed ossification of the carpal bones. Results. Three participants had Vitamin D deficiency rickets confirmed by wrist changes and serology. There was a significantly higher level of Alkaline Phosphatase (p=0.04) in children on ACT than in those who did not receive ACT. Preliminary results show that one third of the children had Vitamin D deficiency. Conclusion. Non ambulatory children with CP are at risk of developing rickets. We recommend regular exposure to sunlight or Vitamin D supplementation as preventative measures. NO DISCLOSURES

Sciatic nerve injury remains a significant and devastating complication of total hip arthroplasty. Incidence as quoted in the literature ranges from 0.08% in primary joint replacement to 7.5% in revision arthroplasty. While as urgent exploration is recommended for nerve palsies associated with pain, management of sciatic nerve palsy with little or no pain is still controversial. In light of this, many patients with persistent palsies are often not referred to our specialist centre until after 6 months post-injury. The aim of this study was to review the outcomes of surgical intervention in patients presenting with sciatic nerve palsy more than 6 months after total hip arthroplasty. This retrospective cohort study identified 35 patients who underwent exploration and neurolysis of the affected sciatic nerve. All patients had documented follow-up at 1, 3, 6, 12 and 18 months to assess sensory and motor recovery. Patients were scored for sensory and motor function in the tibia and common personal nerve divisions, pre and post-operatively. The scoring system devised by Kline et al (1995) was used. Pre-operative electrophysiology was also reviewed. We found a statistically significant functional recovery following neurolysis of the sciatic nerve (p<0.01). A statistically significant relationship was also found between time to neurolysis and recovery of tibial nerve function (p = 0.02), such that greater delay to neurolysis was associated with poorer recovery. There was no significant relationship between time to neurolysis and recovery of common peroneal nerve function (p = 0.28). Our results indicate that the neurolysis of the sciatic nerve, six months or more post injury is associated with functional recovery. We feel that without surgical exploration this clinical improvement would not have occurred. Therefore, we believe that neurolysis plays a vital role at any stage of sciatic nerve injury. However, early presentation to a specialist unit is associated with better outcomes

Purpose. The authors have used the Edinburgh Visual Gait Score (VGS) in the management of diplegic cerebral palsy patients treated with Botulinum toxoid injections into their hamstrings muscles. Video-filmed gait episodes were recorded before and after Botox injections over a treatment period of 6 years from 2007 to 2012. Method. The video-recordings of 32 patients were available for VGS analysis. Ages ranged from 5 to 22 years, with 17 patients under the age of 12 years, and 15 over 12 years. Gross Motor Function Classification System (GMFSC) levels were accorded to: 8 patients level 1, 10 patients level 2, and 14 patients level 3; 15 were boys and 17 girls. The indication for hamstring injections were a GMFCS level of 1 to 3, age five years or older, no previous hamstring surgery, and a patient keen to have the Botox treatment. Video-recordings were taken with a Sony and a Canon Digital camera in a back-front-back view and a lateral left-right view; walking distance ap was 10 metres, lateral camera distance 5 metres. All injections of Botox were done by the senior author without anaesthetic or sedation. All assessments were done by the junior authors; they did not know the patients, the status before or after injections or repeat injections, or the dates of injections and filming of the episodes. Results. After the Botox injections into the hamstrings bilaterally, no patient changed GMFCS level status, nobody deteriorated; all could be classified in the GMFCS. Conclusion. The Edinburgh VGS is a reliable analysis method for classifying GMF levels in diplegic walking cerebral palsy patients. Video-recordings are permanent and can repeatedly be re-assessed in future; different visual parameters may be chosen for assessment. ONE DISCLOSURE

Patient History. This patient is a 59-year-old female who presents with right side hip pain which has gradually progressed over the last 2 years. She describes activity related pain in the right groin radiating down the anterior thigh to the knee. There is also a moderate amount of posterior pain in the ischial region. She is now having pain at night as well as occasional back pain. The patient works as a landscape designer and historically has been quite active participating in yoga, snow skiing, and hiking. These activities have become more limited over the last 12 months. She denies any significant right knee pain and has no radicular complaints. Prior treatment has consisted of physical therapy on two separate occasions over the last year both for 6-week periods without relief. She uses anti-inflammatories daily but otherwise has not had any injections or surgery on the right hip. A cane is used for long distances and her maximum ambulatory capacity is 2 blocks. She is unable to negotiate stairs easily and has difficulty donning socks and shoes. Overall she describes her activity level as light labour. She has no significant past medical or surgical history and takes no medications. The patient is allergic to sulfa drugs. She denies tobacco use. By physical exam she stands 5 feet 4 inches and weighs 150 pounds. Lumbar spine exam shows no tenderness to palpation with negative straight leg raise bilaterally. Right hip exam is consistent with 95 degrees of flexion and 10 degrees extension. Abduction and adduction are 20 degrees and 10 degrees, respectively with 5 degrees of both internal and external rotation. Groin pain is reproduced with passive hip range of motion. Hip flexion and abduction strength are 5/5 with mild tenderness along the greater trochanteric region. Leg lengths are symmetrical. Right knee exam shoes full range of motion with neutral alignment and stability in both the coronal and sagittal planes. Right foot and ankle exam is consistent with normal sensory motor function and palpable dosalis pedis and posterior tibial pulses. X-ray examination demonstrates advanced degenerative changes in the right hip with complete joint space obliteration and early erosive changes in the femoral head. Bone quality shows mild osteoporosis. Impression: Osteoarthritis Right Hip. Plan: Anterior Approach Right Total Hip Arthroplasty

Aim. To assess the risk of hip dislocations in children with cerebral palsy (CP) attending special schools, and the effects of preventative soft tissue surgery (psoas and adductor tenotomy). Method. 110 children were reviewed from 1985-2000. Severity of CP was graded according to the Gross Motor Function Classification System (GMFCS). Hemiplegics - grade 1, Diplegics grades 2 & 3, Quadriplegics grades 4 & 5. Patients were grouped into age groups 5, 10 and 15 years and the number of hip dislocations in each group were noted. Numbers of patients who had preventative soft tissue surgery was also noted. Indication for surgery, >35% femoral head uncovering. Results. Percentage of dislocations increased with CP severity. At 15 years, no dislocations in GMFCS 2, 6% GMFCS 3, 19% GMFCS 4 and 40% in GMFCS 5. The number of patients with at least 1 hip dislocation increased with age at all age groups. GMFCS 4 (age 5 yrs 9%, age 10 yrs 20% and 15 yrs 30%). GMFCS 5 (age5 yrs 22%, age 10 yrs 48% and age 15 yrs 50%). By 15 years, 54 hips in GMFCS 2 & 3 (diplegics), preventative soft tissue surgery had not reduced chances of hip dislocation; only 1 dislocated (2%). In GMFCS 4 & 5 (quadriplegics), dislocations reduced from 40% in those without surgery to 26% in those who had preventive soft tissue surgery. This was particularly so in GMFCS 5 where there was a reduction from 83% dislocation without surgery to 33% with soft tissue preventive surgery. Conclusions. Preventive soft tissue surgery was effective in reducing the rate of hip dislocation in quadriplegic CP especially GMFCS 5

Proximal femoral deformity is common in children with cerebral palsy (CP), contributing to hip instability and ambulation difficulties. This population-based cohort study investigates the prevalence and significance of these deformities in relation to Gross Motor Function Classification System (GMFCS) level. Children with a confirmed diagnosis of CP born within a three-year period were identified from a statewide register. Motor type, topographical distribution and GMFCS level were obtained from clinical notes. Neck Shaft Angle (NSA) and Migration Percentage (MP) were measured from an anteroposterior pelvis x-ray with the hips internally rotated. Measurement of FNA was by the Trochanteric Palpation Test (TPAT) or during fluoroscopic screening of the hip with a guide wire in the centre of the femoral neck. Linear regression analysis was performed for FNA, NSA and MP according to GMFCS level. 292 children were eligible. FNA was increased in all GMFCS levels. The lowest measurements were at GMFCS levels I and II p<0.001. GMFCS levels III, IV, and V were uniformly high p<0.001. Neck shaft angle increased sequentially from GMFCS levels I to V (p<0.001). This study confirms a very high prevalence of increased FNA in children with CP in all GMFCS levels. In contrast, NSA and MP progressed step-wise with GMFCS level. We propose that increased FNA in children with CP represents failure to remodel normal fetal alignment because of delay in ambulation and muscle imbalance across the hip joint. In contrast, coxa valga is an acquired deformity and is largely related to lack of weight bearing and functional ambulation. The high prevalence of both deformities at GMFCS levels IV and V explain the high rate of displacement in these hips and the need for proximal femoral realignment surgery in the prevention and management of hip displacement

Introduction. Typical UK patients spend 5–7 days in hospital following total hip replacement (THR). Decreasing length of stay (LOS) increases throughput and reduces cost. We have developed a short stay THR programme (SSP), which has been used in all patients since May 2006; we present the first 100. Methods. Every patient undergoing THR is included in the dataset. All attend ‘bone school’ before admission, with talks and individual assessments by the senior sister, physiotherapist and occupational therapist. Medical concerns are discussed with an anaesthetist. Patients receive training with crutches; crutches are provided for home practice. All receive an uncemented Corail-Pinnacle THR via piriformis-sparing mini-posterior approach. ‘Low dose’ spinal plus light general anaesthesia provides sensory block whilst retaining motor function; painfree fully weightbearing mobilisation is predictably achieved within four hours. Following radiograph and haemoglobin check next morning, patients are discharged on meeting specific nursing/physiotherapy criteria. Those within 20 miles receive outreach follow-up. Follow-up assessment is undertaken using SF36, Visual Analogue, Merle d'Aubigné-Postel and Oxford Hip Scores. Results. Mean age was 65 years (25–91), mean BMI 28.7 (19–43), mean ASA 1.97 (1–3). Major complications were: one dislocation, one deep infection, one myocardial infarction. Several more minor complications occurred. Mean LOS was 1.99 nights (1–19). One patient was readmitted with wound ooze. No association existed between LOS and ASA/age. 82 patients remain under follow-up, (mean 37.8 months, range 36–61). Seven have died; four underwent revision; seven have moved away or been lost. 97% remain quite or very satisfied. Discussion. We believe our LOS to be amongst the shortest in the country, with favourable clinical results. The SSP succeeds by involving all team-members throughout, and managing patient expectation. At a time of limited healthcare resources we propose that our SSP is totally reproducible, and could readily be established elsewhere with similar benefits

Aims

A flexed knee gait is common in patients with bilateral spastic cerebral palsy and occurs with increased age. There is a risk for the recurrence of a flexed knee gait when treated in childhood, and the aim of this study was to investigate whether multilevel procedures might also be undertaken in adulthood.

Aims

Single-event multilevel surgery (SEMLS) has been used as an effective intervention in children with bilateral spastic cerebral palsy (BSCP) for 30 years. To date there is no evidence for SEMLS in adults with BSCP and the intervention remains focus of debate.

A total of 38 patients with leprosy and localised nerve damage (11 median at the wrist and 37 posterior tibial at the ankle) were treated by 48 freeze-thawed skeletal muscle autografts ranging between 2.5 cm and 14 cm in length. Sensory recovery was noted in 34 patients (89%) and was maintained during a mean period of follow-up of 12.6 years (4 to 14). After grafting the median nerve all patients remained free of ulcers and blisters, ten demonstrated perception of texture and eight recognised weighted pins. In the posterior tibial nerve group, 24 of 30 repairs (80%) resulted in improved healing of the ulcers and 26 (87%) demonstrated discrimination of texture. Quality of life and hand and foot questionnaires showed improvement; the activities of daily living scores improved in six of seven after operations on the hand, and in 14 of 22 after procedures on the foot. Another benefit was subjective improvement in the opposite limb, probably because of the protective effect of better function in the operated side. This study demonstrates that nerve/muscle interposition grafting in leprosy results in consistent sensory recovery and high levels of patient satisfaction. Ten of 11 patients with hand operations and 22 of 25 with procedures to the foot showed sensory recovery in at least one modality.