Introduction. There are conflicting views when assessing the best imaging modality by which to assess long leg alignment pre and post operatively for patients’ receiving primary total hip replacements. It has been a long standing standard that long-leg radiographs are used for measuring and interpreting alignment of the lower limb, but recently it has been suggested that CT imaging may be a better option for this assessment. Methods. Patients awaiting total knee replacement surgeries were invited to participate in this clinical trial. 120 participants’ consented and completed both pre and post-operative long-leg radiographs, and lower limb CT scans. Long leg radiographs were analysed and measured by senior orthopaedic surgeons pre and post-operatively, while CT scans were analysed using the perth protocol method by trained radiologists. Mechanical alignment of the lower limb was calculated using both imaging modalities, the CT “scout” scan was used for the measurement of the mechanical alignment. Pre-operatively the patients had their imaging performed between 1 year and 1 week pre-operatively, and following surgery their imaging was standardised to 6 months post-operatively. For long leg radiographs, patients were asked to stand with their feet shoulder width apart and toes forward facing (on occasion deformities would not allow for this stance, and they were asked to adopt this stance to the best of their ability). Result. The results were analysed using pearsons correlation tests, correlation was shown to be good between the mechanical alignment measurements taken from long leg radiographs, and also from CT scout scans. Preliminary results have shown that correlation between the two modalities is 0.7, displaying a good level of correlation. Interobserver and intra observer analysis of the mechanical alignment taken from long leg radiographs is shown to be excellent with preliminary correlation being 0.9. Conclusion. The correlation results show that CT scans could be using in place of long leg radiographs, and this could assist in measuring the alignment of patients with deformities rendering them unable to stand. Radiation dose has been a main focus of many papers reviewing this correlation previously, but as the mechanical alignment does not require an investigational CT scan to be performed, but only a scout CT scan, the radiation dose is quite comparable to that of a long leg radiograph. CT scan have the additional ability of being able to place the whole image of the leg onto one screen, whereas x-ray of the entire leg required the merging of three different cassettes. This leads to additional human error with the aligning of these cassettes by the radiographer prior to taking the image, and following exposure. CT scans should be considered for measuring the alignment of the lower limb prior to and after total knee replacement

Inter- and intra-observer variation has been noted in the analysis of radiographic examinations with regard to experience of surgeons, and the monitors used for conducting the evaluations. The aim of this study is to evaluate inter/intra observer variation in the measurement of mechanical alignment from long-leg radiographs. 40 patients from the elective waiting list for TKA underwent long leg radiographs pre-operatively and 6 months post-operatively (total of 80 radiographs). The x-rays were analysed by 5 observers ranging in experience from medical student to head orthopaedic surgeon. Two observers re-analysed their results 6 months later to determine intraobserver correlation, and one observer re-measured the alignment on a different monitor. These measurements were all conducted blindly and none of the observers had access to the others’ results. 80 radiographs were analysed in total, 40 pre-op and 40 post-op. The mechanical alignment was analysed using Pearson's correlation (r = 0 no agreement, r = 1 perfect agreement) and revealed that experience as an orthopaedic surgeon has little effect on the measurement of mechanical alignment from long leg radiograph. The results for the different monitor analysis were also analysed using Pearson's correlation of long leg alignment. Monitor quality does seem to affect the correlation between alignment measurements when reviewing both intra and inter observer correlation on different computer monitors. Surgical experience has little impact on the measurement of alignment on long leg radiographs. Of greater concern is that monitors of different resolution can affect measurement of mechanical alignment. As there might be a range of monitors in use in different institutions, and also in outpatient clinics to surgical theatres, close attention should be paid to the implications of these results

In the vast majority of patients, the anatomical and mechanical axes of the tibia in the coronal plane are widely accepted to be equivalent. This philosophy guides the design and placement of orthopaedic implants within the tibia and in both the knee and ankle joints. However, the presence of coronal tibial bowing may result in a difference between these two axes and hence cause suboptimal placement of implanted prostheses. Although the prevalence of tibial bowing in adults has been reported in Asian populations, to date no exploration of this phenomenon in a Western population has been conducted. The aim of this study was to quantify the prevalence of coronal tibial bowing in a Western population. This was an observational retrospective cohort study using anteroposterior long leg radiographs collected prior to total knee arthroplasty in our high volume arthroplasty unit. Radiographs were reviewed using a Picture Archiving and Communication System. Using a technique previously described in the literature for assessment of tibial bowing, two lines were drawn, each one third of the length of the tibia. The first line was drawn between the tibial spines and the centre of the proximal third of the tibial medullary canal. The second was drawn from the midpoint of the talar dome to the centre of the distal third of the tibial medullary canal. The angle subtended by these two lines was used to determine the presence of bowing. Bowing was deemed significant if more than two degrees. The position of the apex of the bow determined whether it was medial or lateral. Measurements were conducted by a single observer and 10% of measurements were repeated by the same observer and also by two separate observers to allow calculation of intraclass correlation coefficients (ICCs). A total of 975 radiographs consecutively performed in the calendar years 2015–16 were reviewed, 485 of the left leg and 490 of the right. In total 399 (40.9%) tibiae were deemed to have bowing more than two degrees. 232 (23.8%) tibiae were bowed medially and 167 (17.1%) were bowed laterally. The mean bowing angle was 3.51° (s.d. 1.24°) medially and 3.52° (s.d. 1.33°) laterally. Twenty-three patients in each group (9.9% medial/13.7% lateral) were bowed more than five degrees. The distribution of bowing angles followed a normal distribution, with the maximal angle observed 10.45° medially and 9.74° laterally. An intraobserver ICC of 0.97 and a mean interobserver ICC of 0.77 were calculated, indicating excellent reliability. This is the first study reporting the prevalence of tibial bowing in a Western population. In a significant proportion of our sample, there was divergence between the anatomical and mechanical axes of the tibia. This finding has implications for both the design and implantation of orthopaedic prostheses, particularly in total knee arthroplasty. Further research is necessary to investigate whether prosthetic implantation based on the mechanical axis in bowed tibias results in suboptimal implant placement and adverse clinical outcomes

We sought to assess the precision of our surgical techniques for total knee replacement in achieving the preoperative plan generated by a combination of MRI scan and long leg radiographs. For each patient in the study, we used the Visionaire system by Smith Nephew to generate a preoperative plan and custom patient instrumentation according to our usual protocols. We then performed on three patients a total knee replacement using three different techniques:. Total knee replacement with standard instrumentation. Total knee replacement with Stryker Computer Navigation. Total knee replacement with Custom Patient Instrumentation by Smith Nephew. During surgery we compared the actual bone cuts performed to the cuts predicted by the Visionaire preoperative plan, component sizing, and postoperatively analyzed the alignment achieved for the total knee replacement. In each case the size used matched the size predicted in our preoperative plan, our bone cuts averaged within 0.5mm of target, and restoration of neutral mechanical alignment of the lower extremity was achieved. We observed that careful preoperative planning improved our surgical outcomes and regardless of instrumentation used a high level of precision could be achieved

Introduction. Restoration of a neutral mechanical axis has been a widely held tenet of primary total knee arthroplasty (TKA), however new technologies are recently being marketed which claim correction of alignment deformity is unimportant. This study was undertaken to determine whether the outcome of aseptic loosening was associated with post-operative mal-alignment of the mechanical axis. Methods. A 1:9 matched case-control analysis was conducted within a cohort of 1,030 consecutive cemented posterior stabilized TKAs with 7 to 11.5 yrs follow-up (average 9 yrs). Aseptic loosening had occurred in 10 knees (1.0%). Nine controls were randomly selected for each case within matching criteria for age and minimum time in situ. Post-operative mechanical alignment was determined using retrieved long leg radiographs. Age-adjusted relative risk was estimated using conditional logistic regression. Results. Radiographs revealed 8 of the 10 loosened cases had been placed in 3 or more degrees varus mechanical alignment (range, 2? varus to 7? varus), compared to only 4 of the 90 age-matched controls (range, 4? valgus to 4? varus). A single degree change of mechanical alignment in the varus direction was associated with a more than 4-fold increase of risk of loosening (odds ratio 4.6, 95% confidence interval 1.7–12.7; p=0.0035). The relative risk for mechanical alignment >= 3? varus compared to <= 2? varus (dichotomous) was 69.2 (95% confidence interval 8.1–589; p=.0001). BMI, gender, and pre-op deformity were not significant. Discussion. These results suggest that avoidance of varus postoperative alignment is an extremely important determinant of TKA fixation durability

Utilisation of unicondylar knee arthroplasty (UKA) has been limited due in part to high revision rates. Only 8% of knee arthroplasty surgeries completed in England and Wales are UKAs. It is reported that the revision rate at 9 years for Total Knee Arthroplasty (TKA) was 3% compared to 12% for UKAs. In the last decade semi active robots have been developed to be used for UKA procedures. These systems allow the surgeon to plan the size and orientation of the tibial and femoral component to match the patient's specific anatomy and to optimise the balancing the soft tissue of the joint. The robotic assistive devices allow the surgeon to execute their plan accurately removing only ‘planned’ bone from the predefined area. This study investigates the accuracy of an imageless navigation system with robotic control for UKA, reporting the errors between the ‘planned’ limb and component alignment with the post-operative limb and component alignment using weight bearing long leg radiographs. We prospectively collected radiographic data on 92 patients who received medial UKA using an imageless robotic assisted device across 4 centres (4 surgeons). This system is CT free, so relies on accurate registration of intra-operative knee kinematic and anatomic landmarks to determine the mechanical and rotational axis systems of the lower limb. The surface of the condylar is based on a virtual model of the knee created intra-operatively by ‘painting’ the surface with the tip of a tracked, calibrated probe. The burring mechanism is robotically controlled to prepare the bone surface and remove the predefined volume of bone. The study shows the 89% of the patients' post-operative alignment recorded by the system was within 30 of the planned coronal mechanical axis alignment. The RMS error was 1.980. The RMS errors between the robotic system's implant plan and the post-operative radiographic implant position was; femoral coronal alignment (FCA) 2.6o, tibial coronal alignment (TCA) 2.9o and tibial slope (TS) 2.9o. In conclusion, the imageless robotic surgical system for UKA accurately prepared the bone surface of the tibia and femur which resulted in low errors when comparing planned and achieved component placement. This resulted in a high level of accuracy in the planned coronal mechanical axis alignment compared to that measured on post-operative radiographs

Purpose. Recently, kinematic aligned total knee arthroplasty (TKA) has gained interest for achieving better clinical outcomes over mechanical aligned TKA. The primary goal of kinematic aligned TKA is to position the femoral and tibial components so that the angles and levels of the distal and posterior femoral joint lines and the tibial joint line are each restored to the patient's natural alignment, and not to a neutral limb alignment that is unnatural for most patients. Despite good clinical outcomes reported at short to mid-term follow-up, surgeons should know reasons why this method is useful and safe surgery and carefully assess the long-term outcomes until this new technique is settled as standardized procedure for TKA. The main purpose of the present study was to compare postoperative radiography and clinical scores following kinematic and mechanical aligned TKA. Methods. Sixty TKAs—30 kinematic and 30 mechanical aligned—were performed in patients with varus-type osteoarthritis using a navigation system. Using postoperative double-leg and single-leg standing long leg radiographs, joint line orientation angle to the floor, conventional mechanical axis (cMA), and true mechanical axis (tMA; line from hip center to the lowest point of calcaneus) were compared between the two groups. One-year after surgeries, range of motion and the patient-derived score of the 2011 Knee Society Score (2011 KSS), which includes four categories: symptoms, patient satisfaction, patient expectations, and functional activities, e.g., walking/standing, standard activities, advanced activities, and discretionary activities, were compared between the two groups. Results. Joint line orientation angles were 1.3 ±1.8 ° varus in the kinematic and 3.2 ± 2.7° valgus in the mechanical group with double-leg standing condition (p<0.05), which were shifted to 0.7 ± 1.7° valgus and 4.3 ± 1.9° valgus with single-leg standing condition, respectively. In double-leg standing condition, cMAs passed through 43.8 ± 10.2 % in the kinematic and 48.7 ± 7.6 % in the mechanical group (p<0.05), which were shifted to 49.2 ± 12.2 % and 53.7 ± 7.5 % in tMA assessment, respectively. Postoperative flexion angle was significantly better in kinematic aligned TKA compared with mechanical aligned TKA (121.7±9.1 vs. 117.3±14.8, p<0.05). Among 4 contents of 2011 KSS, only functional activity score showed better results in the kinematic group compared with the mechanical group (p<0.05). Conclusions. Kinematic aligned TKA exhibited parallel joint line to the floor during single and double-leg standing and neutral weight-bearing in tMA when compared with mechanical aligned TKA, which might result in better functional score

Background. Post-operative (postop) lower limb alignment in unicompartmental knee arthroplasty (UKA) has been reported to be an important factor for postop outcomes. Slight under-correction of limb alignment has been recommended to yield a better clinical outcomes than neutral alignment. It is useful if the postop limb alignment can be predicted during surgery, however, little is known about the surgical factors affecting the postop limb alignment in UKA. The purpose of this study was to examine the influence of the medial tibial joint line elevation on postop limb alignment in UKA. Methods. Seventy-four consecutive medial UKAs were enrolled in this study. All the patients received a conventional fixed bearing UKA. Pre-operative (preop) and postop limb alignment was examined using long leg radiograph and lower limb alignment changes were calculated. Femoral and tibial osteotomy thickness were measured during surgery. Medial tibial joint line change was defined as polyethylene thickness minus tibial osteotomy thickness and sawblade thickness (1.27mm). Positive values indicated a tibial joint line elevation. Medial femoral joint line change was defined as femoral distal component thickness (6.5mm) minus femoral distal osteotomy thickness and sawblade thickness. Positive values indicated a femoral joint line reduction. Medial joint distraction width was also calculated by tibial joint line elevation plus femoral joint line reduction. The correlation of lower limb alignment change with polyethylene insert thickness, the medial tibial joint line elevation, femoral joint line reduction, or joint distraction width were analyzed. Results. The mean preop hip-knee-ankle (HKA) angle was 7.1 ± 3.3° in varus and postop was 2.1 ± 3.0° in varus. The mean lower limb alignment change was 5.0 ± 2.6°. The mean polyethylene insert thickness was 8.5 ± 0.8mm, the tibial joint line elevation was 4.4 ± 1.3mm and the medial femoral joint line reduction was 0.0 ± 1.1mm, the joint distraction width was 4.5 ± 1.5mm. The polyethylene insert thickness, the medial tibial joint line elevation, and the joint distraction width were positively correlated with the lower limb alignment change (R=0.27; P<0.05, R=0.47; P<0.001, R=0.53; P<0.001, respectively) (Figure 1a,b,d). There was no correlation between the medial femoral joint line reduction and the lower limb alignment change (Figure 1c). Discussion. The postop limb alignment in total knee arthroplasty (TKA) is determined by the osteotomy angle of the femur and tibia. On the other hand, it has been reported that the postop alignment in UKA is not influenced by the osteotomy angle but by the insert thickness. Our results indicated that the medial tibial joint line elevation and the joint distraction width were more useful to predict lower limb alignment change than the insert thickness itself. Measuring the medial tibial osteotomy thickness during surgery will help surgeon to predict postop lower limb alignment in UKA. For any figures or tables, please contact authors directly (see Info & Metrics tab above).

The aim of this study is to assess the discrepancy between weight bearing long leg radiographs and supine MRI alignment. There is currently increasing interest in the use of MRI to assess knee alignment and develop custom made cutting blocks utilising this data. However in almost all units MRI scans are performed supine and it is recognised that knee alignment can alter with weight bearing. 46 patients underwent MRI scans as pre-operative planning for Biomet signature total knee replacement and the measure of varus or valgus deformity on MRI was obtained from the plan produced by Biomet Signature software system. 41 of these patients had long leg weight bearing radiographs performed. 33 of these radiographs were amenable to measuring the knee alignment on the picture archiving and communication system (PACS). These measurements were performed by two assessors and inter-observer reliability was satisfactory. There was a significant difference between the alignment as measured on supine MRI compared with weight bearing long leg films. In knee arthroplasty one of the aims is to correct the biomechanical axis of the knee and one of the appeals of custom made cutting blocks is that this can be achieved more easily. However it is important to realise that alignment is not a static value and thus correcting supine alignment may not necessarily result in correction of weight bearing alignment

Introduction. Standard image-free navigation systems have proven to improve the accuracy of components placement and reduce the proportion of outliers for lower limb mechanical axis in total knee arthroplasty (TKA). However, their disadvantages include a longer duration of surgery and pin-tract related complications. More recently, pinless navigation has been developed to address these shortcomings. This study aims to investigate the effectiveness of a new pinless navigation system (Zimmer® iAssist™ Knee) in TKA. Methods. Power analysis was performed. To detect a significant difference in the proportion of outliers for lower limb mechanical axis at a power of 0.80, a sample size of 50 patients would be required. Between May 2013 and April 2014, 50 patients diagnosed with osteoarthritis of the knee were divided into two surgical technique arms: 1) iAssist™; 2) conventional TKA. One Adult Reconstruction surgeon performed all the surgeries. The patients were prospectively followed up and postoperative long leg radiographs were taken at one month post-surgery. Two reviewers blinded to the surgical method performed the measurements on radiographic films. Five radiographic measurements were measured: 1) Hip-Knee-Ankle Angle (HKA); 2) Coronal Femoral-Component Angle (CFA); 3) Coronal Tibia-Component Angle (CTA); 4) Sagittal Femoral-Component Angle (SFA); and 5) Sagittal Tibia-Component Angle (STA), The Mann-Whitney U test was used to compare the two groups for quantitative variables while the Fisher's exact test was used for categorical variables. Results. There was no difference between the two groups for age, BMI, gender and side of operated knee (all p>0.05). There was also no difference in the duration of surgery, postoperative drop in haemoglobin level and transfusion incidence. The median HKA, CFA, CTA, SFA and STA were comparable between both groups [Fig. 1]. Similarly, there was no difference in the proportion of outliers for lower limb alignment (HKA) and components placement (CFA, CTA, SFA and STA) [Fig. 2]. Conclusion. This study does not show any statistical difference in the use of iAssist™ to reduce the proportion of outliers for lower limb alignment and component placement in TKA patients. However this is possibly contributed by the fact that all the surgeries were performed by a single experienced Adult Reconstruction surgeon instead of orthopaedic surgeons in general, thereby reducing the incidence of outliers with conventional technique. In keeping with other studies on pinless navigational systems, this study also found no significant difference in postoperative drop of haemoglobin levels with the use of iAssist™, however this study also found no significant difference in operative time when using iAssist™

Introduction. Total Knee Replacement (TKR) alignment measured intra-operatively with Navigation has been shown to differ from that observed in long leg radiographs (Deep 2011). Potential explanations for this discrepancy may be the effect of weight bearing or the dynamic contributions of soft tissue loads. Method. A validated, 3D, dynamic patient specific musculoskeletal model was used to analyse 85 post-operative CT scans using a common implant design. Differences in coronal and axial plane tibio-femoral alignment in three separate scenarios were measured:. Unloaded as measured in a post-op CT. Unloaded, with femoral and tibial components set aligned to each other. Weight bearing with the extensor mechanism engaged. Scenario number two illustrates the tibio-femoral alignment when the femoral component sits congruently on the tibia with no soft tissue acting whereas scenario three is progression of scenario number two with weight applied and all ligaments are active. Two tailed paired students t-test were used to determine significant differences in the means of absolute difference of axial and coronal alignments. Results. The mean coronal alignment were 1.7° ± 2.1° varus (range, −3.0° to 7.0°), 0.8° ± 2.0° varus (range, −3.7° to 4.8°), 0.4° ± 2.0° varus (range, −3.9° to 5.1°) for unloaded, unloaded with implants set aligned and weight bearing scenarios respectively. The mean of absolute difference in coronal alignment between the unloaded and weight bearing scenario was 1.8° ± 1.5° (range 0.0° to 5.9°). The mean axial alignment were 6.8° ± 5.5° external rotation (ER) (range, 20.0° ER to 11.0° internal rotation (IR)), 5.2° ± 6.1° ER (range, 24.8° ER to 12.6° IR), 7.1° ± 5.5° ER (range, 20.7° ER to 6.8° IR) for unloaded, unloaded with implants set to congruency and weight bearing scenarios respectively. The mean of absolute difference in axial alignment between the unloaded and weight bearing scenario was 2.8° ± 2.0° (range 0.1° to 8.8°). Statistically significant absolute differences in coronal and axial alignments were found. Conclusions. ‘Correct’ alignment has long been considered and important predictor of longevity and function following TKR surgery (Sikorski 2008). However, recent reports have challenged these long held beliefs. One possible reason is that these alignments are measured in static condition, not in a functional position where soft tissue is active. This study showed that knee joint alignment changes significantly between unloaded and loaded scenarios. This suggest that static, unloaded measurements do not represent functional alignment. Thus, tibio-femoral alignment measured from unloaded condition may not describe a ‘correct’ alignment for a particular patient. Further work should focus on dynamic and functional descriptions of component and/or limb alignment

Introduction. Patient matched instrumentation (PMI) have been proposed the accuracy of bone cuts through custom cutting blocks and provide the proper alignment of total knee arthroplasty (TKA). On the other hand, there are some reports that the introduction of PMI for guiding bone cuts could increase the incidence of malalignment in primary TKA. Recent comparisons between patient-specific cutting guides and quantitative assessments of postoperative alignment have revealed the presence of outliers with respect to coronal alignment. The purpose of this study was to assess the implanted component alignment post-operatively between one type of MRI based PMI (Visionaire; Smith & Nephew, Inc, Memphis, Tenn) and conventional surgical instrumentation (CI) using radiographs and CT scan. Methods. 32 knees in 32 patients (25 women) with medial type knee osteoarthritis were underwent cruciate retaining TKA between September 2013 and May 2015, and were included in this study. Preoperative MRI scanning of the hip, knee, and ankle was performed for PMI group (n=12) and CT scanning was performed for CI group (n=20) 6 weeks before surgery according to a standard scanning protocol to determine the surgical epicondylar axis (SEA). Postoperatively, we compared operation time, blood loss, and mechanical alignment of two groups. Post-surgical mechanical alignments such as hip-knee-ankle angle (HKA), frontal femoral component angle (FFC), and frontal tibial component angle (FTC) were determined using long leg radiographs (Fig. 1). CT scans were used to assess the condylar twist angle (CTA) made by SEA and posterior condylar axis (Fig. 2). Each measurement was performed by two, blinded independent observers, and interclass correlation for each measurement was calculated. A student's two-tailed t test was used to compare the two cohorts, with statistical significance set at a p-value of <0.05. Results. There was no significant difference between the two groups regarding preoperative age, body mass index, degree of mechanical deformity, mean operation time or mean blood loss. Mean pre / postoperative HKA in the PMI group was 166.8 ± 6.4°/ 176.7 ±1.9° and 168.3 ±8.3° / 178.8 ±2.1°in the CI group. There was no significant difference between two groups, but there were fewer ± 3° HKA outliers with CI group (20%) than with PMI group (50%). Postoperative FFC was 89.1 ± 0.6° in PMI group and 88.1 ± 1.2° in CI group. FTC was 87.8 ± 1.4° in PMI group and 89.3 ± 1.6° in CI group. CTA was −0.8 ± 0.6 ° in PMI group and −1.2 ± 1.1° in CI group. There was no significant difference between PMI and CI group in postoperative mechanical alignment, but there were higher ± 3° FTC outliers in PMI group (50%) compared to CI group (10%)(p=0.01). (Fig.3). Discussion and Conclusion. Although the overall mean mechanical alignment for PMI group was similar to CI group, these results suggest that PMI did not significantly improve alignment. It should be recommended to use only for the femoral component. To view tables/figures, please contact authors directly

Introduction. Unicondylar knee replacement (UKR) surgery is proven long term results in its benefit in medial compartment OA. However, its results are sensitive to component alignment with poor alignment leading to early failure. The advent of computer navigation has resulted in improved mechanical alignment, but little has been published on the outcomes of navigated UKR surgery. We present the results of 253 consecutive Computer Assisted UKR's performed by a single surgeon. Objective. Assess clinical and radiological outcomes of Computer Assisted Unicondylar Knee Replacement at 5 years follow-up. Methods. Between August 2003 and June 2007, 253 UKR's were performed by a single surgeon using the Stryker Knee navigation system. Pre-operative Knee Society Scores (KSS) were recorded. The UKR's consisted of 98 oxford UKR's and 155 MG UKR's. Tourniquet time, time to straight leg raise and time to discharge was also recorded. All patients had post op KSS scores and long leg standing radiographs. Data regarding revision surgery was also collected. Results. Pre-op mean KSS scores was 54 (24–62) and post-op scores were a mean of 89 (75–100). 92% percent of femoral components were aligned at 90+/− 4 degrees from neutral in the coronal plane whilst eighty nine percent of tibial components were aligned at 90+/− 4 degrees from neutral in the coronal plane. Mean tourniquet time was 53 minutes whilst 98% of patients had SLR at 24hours. Only two percent of patients had an overall valgus alignment of their limb at the end of the procedure on long leg radiographs. 1% of the UKRs underwent revision for loosening of the femoral component. 1 oxford UKR was revised for progression of patello-femoral disease. One MG UKR was revised for unexplained pain. Conclusion. Our single surgeon series of Computer Assisted UKR demonstrates favourable outcomes in the medium term with 98% survival at 5 years. Computer Assisted UKR allows accurate and reproducible alignment of the tibial and femoral component. We recommend the use of Computer Navigation in performing Unicondylar Knee Replacements

Introduction. There is a controversy with regard to the treatment of osteoarthritis (OA) of the knee in patients with considerable deformities of the femoral or tibial shafts. Some surgeons prefer to correct the deformity while performing TKA at the level of the knee joint. However, this technique requires accurate planning and execution of the planned cuts. In addition, the use of intramedullary guides in such cases may not be possible or desirable and may lead to complications. There is a strong indication for using navigation in such cases. Methods. The navigation technique was used in both laboratory and clinical setting, First, we compared between navigational and conventional techniques in performing TKA in 24 plastic knee specimens (Sawbones, Sweden) that have osteoarthritic changes and complex tibial or femoral deformities. A demo kit for conventional instrumentation of posterior stabilised TKA (Scorpio, Stryker) was used for 12 cases and an image-free navigation system (Stryker) was used for a corresponding 12 cases. There were 4 different deformities; severe mid-shaft tibial varus, severe distal third femoral valgus, complex deformity distal femur and deformity following a revision TKA. The surgical procedures were performed by 3 arthroplasty surgeons, each surgeon operated on 8 knee specimens (4 knees in each arm of the study with 4 different deformities). Deformities were corrected at the level of the knee joint during TKA without prior osteotomies. For conventional techniques, surgeons used a combination of both intramedullary and extramedullary guides. Postoperative long leg radiographs were used to assess coronal alignment. Second, we used the same navigational technique clinically to perform TKA in patients with extra-articular deformities. Results. Using both navigational and conventional techniques, it was possible to indirectly correct shaft deformities by adjusting the inclination of bone cuts at the level of the knee joint. The amount of bone cutting at distal femur and proximal tibia were variable depending on the location and direction of the deformity. There was no compromise of collateral ligaments or patellar tendons in both techniques. However, the accuracy of restoring normal alignment was better in navigational techniques. The results of the clinical cases are still in progress waiting analysis of a longer term follow up. Discussion. Navigational techniques eliminated the use of both intramedullary and extramedullary guides. The improved accuracy with navigational techniques led to better alignment that can improve functional and survival outcome of similar cases of TKA in real patients

Introduction. Malalignment of lower limb is a common feature in patients with osteoarthritis (OA). This, either cause or effect of OA, is known to alter the normal anatomy of knee and affects progression of wear and tear in mechanically stressed compartment. We investigated the relationship of mechanical axis to wear and tear in varus, neutral and valgus knees. Materials and Methods. A retrospective analysis of 136 consecutive patients, with OA, who underwent total knee replacement using computer navigation. The thickness of medial and lateral cuts of distal femur and proximal tibia were recorded. Pre-op coronal deformity was assessed using long leg radiographs and Femoral Tibial Mechanical Angle (FTMA) calculated. Patients were evaluated as one group and three subgroups based on preop varus, neutral or valgus lower limb alignment. Student t test and Pearson's correlation coefficient were used for statistical analysis. Results. When considered as a whole group (136 patients) there was a significant difference between the medial and lateral cuts on both femoral and tibial side (p <0.001). We also found a significant negative correlation between FTMA and femoral lateral cut (r = −0.45). In varus group (103 patients) tibial medial and lateral cuts were significantly different (p<0.05) while there was no significant difference in femoral medial and lateral cuts. In valgus group (n=23) there was a significant difference between the femoral medial and lateral cuts (p<0.0001) while no significant difference was found between tibial medial and lateral cuts. Intergroup comparison showed that there was a significant difference between the varus and valgus group with regards to femoral medial cut, femoral lateral cut and tibial medial cut (all p<0.01). There was no significant difference between the tibial lateral cut between the varus and valgus group. We found a significant negative correlation between tibial lateral cut and FTMA in valgus group (r=-0.68). Discussion. In both varus and neutral group tibial lateral cut was more as compared to medial cut and this difference was significant while there was no significant difference between femoral medial and tibial cuts. This emphasises the point that in varus and neutral knees tibial side wear is responsible for causing the deformity as compared to femoral. There was no significant difference in tibial lateral cut between varus and valgus group. In valgus knees femoral side is responsible for producing malalignment rather than tibial side and less amount of lateral femur removal is required but amount of lateral tibial removal is not significantly different. This study shows that varus deformity is mainly a tibial phenomenon while valgus deformity mainly occurs in femur. Surprisingly, approximately a mean 9 mm of lateral tibial cut was required, irrespective of whether the patient had varus, neutral or valgus preop lower limb alignment

INTRODUCTION. In Total Knee Arthroplasty (TKA), the neutral overall limb alignment (NOLA), i.e. the mechanical alignment of the lower limb within 0°±3°, is targeted for achieving good clinical/functional results. The kinematic overall limb alignment (KOLA), which uses the axis through the centres of the femur posterior condyles modelled as cylinders, represents a novel approach for achieving better soft tissue balance. Patient-specific instrumentation (PSI) is nowadays offered as an effective technology in TKA to obtain better lower limb alignments than those via conventional guides (CON). Although relevant results are still inconsistent, the benefits claimed include shorter operative time, reduced surgical instrumentation, and accurate preoperative planning. The aim of this study was to report the preliminary clinical and radiological results of TKA patients operated via NOLA-PSI and KOLA-PSI. Comparisons between them and with the results obtained via NOLA-CON were performed. PATIENTS AND METHODS. A four-centre randomised study on 144 patients has been designed to assess these three techniques. In each centre, 36 patients are planned to be operated, 12 per technique. Currently, in our centre 18 patients have been operated so far: 6 via NOLA-CON (Group A), 3 via NOLA-PSI (Group B), and 9 via KOLA-PSI (Group C). All patients were implanted with a cruciate-retaining TKA (Triathlon®, Stryker®-Orthopaedics, Mahwah, NJ-USA) with patella resurfacing, those in PSI groups according to Otismed® imaging protocol. This includes pre-operative MRI scans at the hip, knee and ankle joints. Clinical evaluations were performed pre-operatively, at 45 days, and 3, 6 and 12 months post-operatively using the knee and functional IKSS (International Knee Society Score). At 45 days post-operatively a weight-bearing long leg radiograph was performed to measure possible differences between planned and implanted component alignment in patients operated via NOLA groups (A and B) and via KOLA group (C). RESULTS. The post-operative knee and functional scores at the most recent follow-up in NOLA groups (A and B) were 78±19 (minimum÷maximum, 51÷95) and 80±23 (45÷100), respectively; in group C these were 91±12 (65÷100) and 89±15 (60÷100). The mean alignment of the mechanical axis in the coronal plane in NOLA-CON (group A) was 1.5° in varus, the 20% being larger than 3° and considered as outliers. In the PSI groups (B and C), the mean absolute difference with respect to the planned alignment was 0.7°, without outliers. Only one complication was observed (group B), where a manipulation was necessary two months after TKA due to small knee motion range. DISCUSSION. The present results in PSI showed good accuracy and reproducibility of the planned alignments with respect to those achieved during surgery. Particularly, KOLA showed better clinical/functional results, without soft tissue release; the 25% of the remaining patients had medial or lateral structure release. KOLA seems the ideal reference in TKA, though it does not reflect normal morphology. However, lower limb alignment larger than 3° has been estimated in an important fraction of the normal adult population. In conclusion these preliminary results revealed a good efficacy of the examined PSI, in general, and better clinical results via KOLA