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The Bone & Joint Journal
Vol. 98-B, Issue 9 | Pages 1262 - 1269
1 Sep 2016
Pinder EM Bottle A Aylin P Loeffler MD

Aims. To determine whether there is any difference in infection rate at 90 days between trauma operations performed in laminar flow and plenum ventilation, and whether infection risk is altered following the installation of laminar flow (LF). Patients and Methods. We assessed the impact of plenum ventilation (PV) and LF on the rate of infection for patients undergoing orthopaedic trauma operations. All NHS hospitals in England with a trauma theatre(s) were contacted to identify the ventilation system which was used between April 2008 and March 2013 in the following categories: always LF, never LF, installed LF during study period (subdivided: before, during and after installation) and unknown. For each operation, age, gender, comorbidity, socio-economic deprivation, number of previous trauma operations and surgical site infection within 90 days (SSI90) were extracted from England’s national hospital administrative Hospital Episode Statistics database. Crude and adjusted odds ratios (OR) were used to compare ventilation groups using hierarchical logistic regression. Subanalysis was performed for hip hemiarthroplasties. Results. A total of 803 065 trauma operations were performed during this time; 19 hospitals installed LF, 124 already had LF, 13 had PV and the type of ventilation was unknown in 28. Patient characteristics were similar between the groups. The rate of SSI90 was similar for always LF and PV (2.7% and 2.4%). For hemiarthroplasties of the hip, the rates of SSI90 were significantly higher for LF compared with PV (3.8% and 2.6%, OR 1.45, p = 0·001). Hospitals installing LF did not see any statistically significant change in the rate of SSI90. Conclusion. The results of this observational study imply that infection rate is similar when orthopaedic trauma surgery is performed in LF and PV, and is unchanged by installing LF in a previously PV theatre. Cite this article: Bone Joint J 2016;98-B:1262–9


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_3 | Pages 3 - 3
23 Jan 2024
Lewandowski D Hussein A Matthew A Ahuja S
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Laminar flow theatres were first introduced in the United Kingdom in the 1960s and 1970s and have become standard in orthopaedic surgery involving implants. A study from 1982 showed a 50% reduction in infections with joint arthroplasties when compared to conventional theatres and laminar flow became standard in the following decades. Recent evidence including a meta-analysis from 2017 questions the effectiveness of these theatre systems. Most of the evidence for Laminar flow use is based on arthroplasty surgery. We aimed to determine the effect of using non-laminar flow theatres on our trauma patients. A total of 1809 patients who had trauma surgery were identified from 2019 to 2021. 917 patients were operated on in a laminar theatre and 892 in a non-laminar theatre across two operating sites. We identified the surgical site infections as reported through our surveillance program within the first 90 days of infection. Patient co-morbidities were noted through patient records and procedure length was also noted. Of the 1809 trauma patients identified between the years of 2019 and 2021, 917 patients had operations in a laminar flow theatre and 892 in a non-laminar theatre. Of the 892 operated in non-laminar flow theatres, 543 were operated in the University Hospital of Wales (UHW) and 349 at the University Hospital of Llandough (UHL). An analysis of soft tissue infections and hospital acquired infections post-operatively demonstrated 15/543 and 71/543 respectively for non-laminar UHW infections and 4/349 and 21/349 for non-laminar UHL infections. A look at laminar flow patients showed 25/917 with soft tissue infections and 86/917 hospital acquired infections. There was no difference between laminar and non-laminar flow theatre infection rates showing rates of 12.1% and 12.2% respectively. In our trauma patients we noticed no significant advantage of using laminar flow theatres when compared to non-laminar flow theatres. This is in keeping with some recently published literature. Laminar flow theatres have been shown to decrease airborne pathogen counts under controlled conditions, but we conclude in the day to day environment of trauma theatres these conditions are either not met or that the theoretical advantage of laminar flow does not translate to a direct advantage of reduction of infections which may be achieved by standard prophylactic antibiotics


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 408 - 408
1 Apr 2004
Kochhar T Back D Wright M Ker N
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This study addresses four questions:. Does laminar flow exist in our operating theatres?. Do perioperative warming blankets affect laminar flow?. Do perioperative warming blankets cause displacement of particles into a wound perioperatively?. Do conventional theatres have adequate airflow?. It has been widely recognised that laminar flow theatres decrease colony forming units in operating theatres and thus decrease the risk of infection in arthroplasty surgery. It is also accepted that perioperative warming blankets improve patient haemodynamic stability and may reduce the risk of wound infection. However, there has been great debate as to whether these perioperative warming blankets cause disruption of laminar flow and excess displacement of dust into a wound, and thus increase the risk of infection of total joint arthroplasty surgery. Using digital video imaging and airflow measurement techniques as used in formula 1 racing design, this independent study reveals that the Bair Hugger system has no effect on laminar flow or paticle displacement. It also shows that factors out of the surgeon’s control disrupt laminar flow and that general theatre design may be inherently flawed. This would seriously affect the risk of infection


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_11 | Pages 56 - 56
1 Nov 2022
Thimmegowda A Gajula P Phadnis J Guryel E
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Abstract. Aim. To identify the difference in infection rates in ankle fracture surgery in Laminar and Non Laminar flow theatres. Background. The infection rates in ankle fracture surgery range between 1–8%. The risk factors include diabetes, alcoholism, smoking, open fractures, osteoporotic fractures in the elderly, and high BMI. Laminar flow has been shown to reduce infections in Arthroplasty surgeries. Therefore, it has become mandatory to use in those procedures. However, it's not the same with ankle fracture surgery. Materials and Methods. It was a retrospective study. The data was collected over a 5 year period between 2015 and 2020. It was collected from Blue spier, Panda, and theatre register. There were 536 cases in each group i.e. Laminar flow (LF) and Non-Laminar flow (NLF). The variables looked at were: 1. Superficial and deep infection rates in LF and NLF theatres, 2. The number of open fractures, 3. Type of ankle fractures (Bimalleolar, Trimalleolar), 4. The number of infected cases who had external fixation prior to ORIF, 5. The number of cases that had Plastics reconstructive procedures, and 6. The grade of the operating surgeon. Conclusions. Superficial infection rate between NLF and LF was not significantly different 11.5% vs 10.3%. The deep infection rate was statistically significant against NLF theatres at 6.34% vs 4.29%. The open fracture was a major contributing factor for deep SSI (14.7% vs 26%). The application of an external fixator in LF and NLF theatres did not alter the infection. rates. Bimalleolar fractures were associated with a higher infection rate


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 203 - 203
1 Mar 2003
Hardy A Lamberton T
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The purpose of this study was to determine whether a laminar flow operating system reduces deep infection rates in Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA) and to examine the costs involved in implementing laminar flow technology. A retrospective analysis of deep infection rates in 759 patients who underwent THA and TKA was performed in one hospital prior to and after the introduction of a vertical laminar flow operating system together with the use of isolation body exhaust suits. A cost analysis was also performed on the cost of implementing laminar flow technology and the average inpatient hospital cost of managing a deep infection. A control group consisted of 387 THA and TKA performed in 2 years in a conventional operating theatre and follow up carried out to a mean of 29 months. There were 12 recorded deep infections, 3.1%. Case group consisted of 372 THA and TKA performed in 2 years after the introduction of a vertical laminar flow operating theatre together with the use of isolation body exhaust suits, with a mean follow up to 22 months. There were 4 recorded deep infections, 1.1%. A comparison of deep infection rates yielded p value 0.06. There was a strong trend toward a reduction in deep infection rate in THA and TKA performed in the laminar flow theatre with the use of isolation body exhaust suits. The economic impact of deep infection in THA and TKA is vast and the cost of implementing laminar flow technology must be weighed against the deep infection rate as well as the number of operations performed at an institution


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 153 - 153
1 Apr 2005
Patel S Reed M Lamberton A Blackley H Hardy A
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i. Purpose To determine whether operating in ultra-clean vertical laminar flow and personal isolation “space suits” reduces deep infection rates in total knee replacement compared to a conventional theatre and modern disposal gowns. ii. Method An analysis of deep infection rates in 373 patients who underwent total knee arthroplasty performed in one operating theatre prior to and after a theatre and clothing upgrade. Results The infection rate before the introduction of ultraclean air and space suits was 6/166 (3.6%). Afterwards the rate was 1/207 (0.5%). This shows a significant reduction (p< 0.05). iii. Conclusion Compared to conventional theatres and clothing the use of ultraclean vertical laminar flow and spacesuits significantly reduces the risk of infection in total knee arthroplasty


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 358 - 358
1 May 2009
Odutola Tasker A Ashmore A Omari A
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Aim: To determine the effects of the different types of headgear on bacterial shedding in laminar flow theatres. Material and Methods: Sham experiments were carried out using standard theatre clothing, sterile gowns and face masks with visors. Three experimental groups were utilised; no headgear (control), surgeons hoods or fabric balaclavas (known colloquially as “chicken hats”). The sham experiments consisted of two surgeons, scrubbed and gowned, both wearing the same headgear, talking and moving hands for 30 minutes over a sterile mock operating field. 5 bacterial plates were placed on the sterile sheets to capture shed bacteria. An additional 5 plates were placed above head height in the laminar flow enclosure. An air sampler was positioned within the laminar flow and set off for the middle 5 mins of the experiment. Plates were then incubated for 48hrs at 37oC and the number of colony forming units at head and waist height as well as in the air sampler were counted. Each experiment was repeated 5 times. Results: The bacterial shedding rate at waist height was 0.2 CFUs/plate (314 CFUs/m2/hr) for the control experiment, 0 CFUs/plate (0 CFUs/m2/hr) for the surgeons hoods and 0.08 CFUs/plate (126 CFUs/m2/hr) for the fabric balaclavas. Conclusion: These experiments show very low bacterial shedding rates with standard clothing and headgear in laminar flow theatres. Although these results demonstrate worse bacterial shedding with fabric balaclavas (which contradicts conventional thinking), the low rate of shedding rates means the results are not statistically significant. It therefore raises the question as to whether we should be using the more expensive fabric balaclavas without proven benefit, and the possibility of increased bacterial shedding


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXI | Pages 167 - 167
1 May 2012
G. H A. R M. W C. F
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Introduction. Reducing infection in total joint replacement by using ultra clean air and protective enclosed suits (space suits) has become the standard in many operating theatres without good supporting evidence. This study examined the impact of laminar flow and space suits on the rate of revision for early infection following total hip (THR) and knee (TKR) replacement. Method. We used the 10-year results of the New Zealand Joint Registry to compare the rates of revision for early infection between laminar flow and conventional theatres both with and without the use of space suits. We separated hospitals and surgeons who had worked with and without space suits in both environments to exclude other confounding variables. Results. There were 51,485 THR and 36,826 TKR registered with laminar flow theatres used for 50% of the procedures and space suits used in 44% of cases. In THR there was a significant increase in revision for early infection in those procedures performed with the use of a space suit (p< 0.0001), for those performed in a laminar flow theatre (p< 0.003) and those procedures performed in a laminar flow theatre with a space suit (p< 0.001). The results were similar in TKR with the use of a space suit (p< 0.001), in laminar flow theatres (p< 0.019) and when laminar flow and space suits were used (p< 0.001). The results were unchanged when the surgeons and hospitals were analysed individually. Conclusion. The rate of revision for early infection has not been reduced by using laminar flow and space suits. The results of this study question the rationale for the increasing use and cost to the health system of these modalities in routine joint replacement


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 1 | Pages 85 - 90
1 Jan 2011
Hooper GJ Rothwell AG Frampton C Wyatt MC

We have investigated whether the use of laminar-flow theatres and space suits reduced the rate of revision for early deep infection after total hip (THR) and knee (TKR) replacement by reviewing the results of the New Zealand Joint Registry at ten years. Of the 51 485 primary THRs and 36 826 primary TKRs analysed, laminar-flow theatres were used in 35.5% and space suits in 23.5%. For THR there was a significant increase in early infection in those procedures performed with the use of a space suit compared with those without (p < 0.0001), in those carried out in a laminar-flow theatre compared with a conventional theatre (p < 0.003) and in those undertaken in a laminar-flow theatre with a space suit (p < 0.001) when compared with conventional theatres without such a suit. The results were similar for TKR with the use of a space suit (p < 0.001), in laminar-flow theatres (p < 0.019) and when space suits were used in those theatres (p < 0.001). These findings were independent of age, disease and operating time and were unchanged when the surgeons and hospital were analysed individually. The rate of revision for early deep infection has not been reduced by using laminar flow and space suits. Our results question the rationale for their increasing use in routine joint replacement, where the added cost to the health system seems to be unjustified


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_15 | Pages 62 - 62
1 Dec 2021
Wang Q Goswami K Xu C Tan T Clarkson S Parvizi J
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Aim. Whether laminar airflow (LAF) in the operating room (OR) is effective for decreasing periprosthetic joint infection (PJI) following total joint arthroplasty (TJA) remains a clinically significant yet controversial issue. This study investigated the association between operating room ventilation systems and the risk of PJI in TJA patients. Method. We performed a retrospective observational study on consecutive patients undergoing primary total knee arthroplasty (TKA) and total hip arthroplasty (THA) from January 2013-September 2017 in two surgical facilities within a single institution, with a minimum 1-year follow-up. All procedures were performed by five board-certified arthroplasty surgeons. The operating rooms at the facilities were equipped with LAF and turbulent ventilation systems, respectively. Patient characteristics were extracted from clinical records. PJI was defined according to Musculoskeletal Infection Society criteria within 1-year of the index arthroplasty. A multivariate logistic regression model was performed to explore the association between LAF and risk of 1-year PJI, and then a sensitivity analysis using propensity score matching (PSM) was performed to further validate the findings. Results. A total of 6,972 patients (2,797 TKA, 4,175 THA) were included. The incidence of PJI within 1 year for patients from the facility without laminar flow was similar at 0·4% to that of patients from the facility with laminar flow at 0·5%. In the multivariate logistic regression analysis, after all confounding factors were taken into account, the use of LAF was not significantly associated with reduction of the risk of PJI. After propensity score matching, there was no significant difference in the incidence of PJI within 1 year for patients between the two sites. Conclusions. The use of LAF in the operating room was not associated with a reduced incidence of PJI following primary TJA. With an appropriate perioperative protocol for infection prevention, LAF does not seem to play a protective role in PJI prevention


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 514 - 514
1 Aug 2008
Spitzer A Goodmanson P Evensen K Habelow B Suthers K
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Purpose: Infection after TJA is a rare but devastating complication. Horizontal laminar airflow has been advocated to reduce infection rate. Methods: 896 consecutive primary and revision total joint arthroplasties of the hip and knee were retrospectively reviewed. The first 751 were performed before February 2004 in a horizontal laminar air flow room; the final 146 were performed without laminar flow from February 2004 through May 2005. All patients received the same perioperative antibiotics, wound management, and rehabilitation program. Body exhaust systems were worn in all cases. Results: There were a total of 10 infections (1.1%) requiring surgical treatment, including 6 deep knee infections (0.67%), and four (0.45%) wounds (3 knees and 1 hip) with delayed healing or superficial infections. 9 of the infections occurred in the laminar flow group (1.2%), including all 6 deep knee infections (6/456=1.3%), 2 knee and 1 hip wound infection. Only 1 infection (0.68%), in a knee wound, occurred in the non-laminar flow group. There were no deep hip infections. Statistically, more knees became infected than hips overall (9/550=1.64% vs 1/346=0.29%)(p< 0.01) and more knees developed deep infection with laminar flow than without (6/456=1.2% vs 0/94=0.00%)(p< 0.1). Conclusions: Laminar air flow did not alter the infection rate in THA, but may have increased infection rate in TKA. Infection is multifactorial, and longer follow up of the non-laminar flow group may reduce the differences seen. Nevertheless, this data agrees with other published data and is of significant concern for the TKA surgeon and patient alike


The Bone & Joint Journal
Vol. 99-B, Issue 8 | Pages 1061 - 1066
1 Aug 2017
Refaie R Rushton P McGovern P Thompson D Serrano-Pedraza I Rankin KS Reed M

Aims. The interaction between surgical lighting and laminar airflow is poorly understood. We undertook an experiment to identify any effect contemporary surgical lights have on laminar flow and recommend practical strategies to limit any negative effects. Materials and Methods. Neutrally buoyant bubbles were introduced into the surgical field of a simulated setup for a routine total knee arthroplasty in a laminar flow theatre. Patterns of airflow were observed and the number of bubbles remaining above the surgical field over time identified. Five different lighting configurations were assessed. Data were analysed using simple linear regression after logarithmic transformation. Results. In the absence of surgical lights, laminar airflow was observed, bubbles were cleared rapidly and did not accumulate. If lights were placed above the surgical field laminar airflow was abolished and bubbles rose from the surgical field to the lights then circulated back to the surgical field. The value of the decay parameter (slope) of the two setups differed significantly; no light (b = -1.589) versus one light (b = -0.1273, p < 0.001). Two lights touching (b = -0.1191) above the surgical field had a similar effect to that of a single light (p = 0. 2719). Two lights positioned by arms outstretched had a similar effect (b = -0.1204) to two lights touching (p = 0.998) and one light (p = 0.444). When lights were separated widely (160 cm), laminar airflow was observed but the rate of clearance of the bubbles remained slower (b = -1.1165) than with no lights present (p = 0.004). . Conclusion. Surgical lights have a significantly negative effect on laminar airflow. Lights should be positioned as far away as practicable from the surgical field to limit this effect. Cite this article: Bone Joint J 2017;99-B:1061–6


Bone & Joint Open
Vol. 5, Issue 10 | Pages 894 - 897
16 Oct 2024
Stoneham A Poon P Hirner M Frampton C Gao R

Aims. Body exhaust suits or surgical helmet systems (colloquially, ‘space suits’) are frequently used in many forms of arthroplasty, with the aim of providing personal protection to surgeons and, perhaps, reducing periprosthetic joint infections, although this has not consistently been borne out in systematic reviews and registry studies. To date, no large-scale study has investigated whether this is applicable to shoulder arthroplasty. We used the New Zealand Joint Registry to assess whether the use of surgical helmet systems was associated with lower all-cause revision or revision for deep infection in primary shoulder arthroplasties. Methods. We analyzed 16,000 shoulder arthroplasties (hemiarthroplasties, anatomical, and reverse geometry prostheses) recorded on the New Zealand Joint Registry from its inception in 2000 to the present day. We assessed patient factors including age, BMI, sex, and American Society of Anesthesiologists (ASA) grade, as well as whether or not the operation took place in a laminar flow operating theatre. Results. A total of 2,728 operations (17%) took place using surgical helmet systems. Patient cohorts were broadly similar in terms of indication for surgery (osteoarthritis, rheumatoid arthritis, fractures) and medical comorbidities (age and sex). There were 842 revisions (5% of cases) with just 98 for deep infection (0.6% of all cases or 11.6% of the revisions). There were no differences in all-cause revisions or revision for deep infection between the surgical helmet systems and conventional gowns (p = 0.893 and p = 0.911, respectively). Conclusion. We found no evidence that wearing a surgical helmet system reduces the incidence of periprosthetic joint infection in any kind of primary shoulder arthroplasty. We acknowledge the limitations of this registry study and accept that there may be other benefits in terms of personal protection, comfort, or visibility. However, given their financial and ecological footprint, they should be used judiciously in shoulder surgery. Cite this article: Bone Jt Open 2024;5(10):894–897


The Bone & Joint Journal
Vol. 98-B, Issue 3 | Pages 334 - 340
1 Mar 2016
Tayton ER Frampton C Hooper GJ Young SW

Aims. The aim of this study was to identify risk factors for prosthetic joint infection (PJI) following total knee arthroplasty (TKA). . Patients and Methods. The New Zealand Joint Registry database was analysed, using revision surgery for PJI at six and 12 months after surgery as primary outcome measures. Statistical associations between revision for infection, with common and definable surgical and patient factors were tested. Results. A total of 64 566 primary TKAs have been recorded on the registry between 1999 and 2012 with minimum follow-up of 12 months. Multivariate analysis showed statistically significant associations with revision for PJI between male gender (odds ratio (OR) 1.85, 95% confidence interval (CI) 1.24 to 2.74), previous surgery (osteotomy (OR 2.45 95% CI 1.2 to 5.03), ligament reconstruction (OR 1.85, 95% CI 0.68 to 5.00)), the use of laminar flow (OR 1.6, 95% CI 1.04 to 2.47) and the use of antibiotic-laden cement (OR 1.93, 95% CI 1.19 to 3.13). There was a trend towards significance (p = 0.052) with the use of surgical helmet systems at six months (OR 1.53, 95% CI 1.00 to 2.34). Conclusion. These findings show that patient factors remain the most important in terms of predicting early PJI following TKA. Furthermore, we found no evidence that modern surgical helmet systems reduce the risk of PJI and laminar flow systems may actually increase risk in TKA. The use of this registry data assists the estimation of the risk of PJI for individual patients, which is important for both informed consent and the interpretation of infection rates at different institutions. . Take home message: Infection rates in TKA are related to both individual patient and surgical factors, and some modern methods of reducing infection may actually increase infection risk. . Cite this article: Bone Joint J 2016;98-B:334–40


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 465 - 466
1 Apr 2004
Smith P Terweil E Cahill J Scarvell J
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Aim: To determine the cost of medical treatment of infection following total joint replacement (TJR) of the hip or knee. With this information, and obtaining the current costs of antibiotics, antibiotic loaded cement and laminar flow theatres, we aimed to calculate the relative cost- benefit of these prophylactic strategies to prevent infection. Method: Fifty two patients who were admitted to The Canberra Hospital (TCH) for treatment of infection at following total joint arthroplasty between January 1996 and January 2001. A detailed cost analysis of treatment costs following infection was performed. All ward, theatre, prosthesis, investigation, pharmaceutical, allied health and medical costs were collated to produce a total cost of treatment. Current costs of prophylactic antibiotics, antibiotic cement and laminar flow theatres were obtained from suppliers. Costs were calculated for different combinations of prophylactic measures using the rates of deep periprosthetic infection reported through the Swedish Arthroplasty Registry. Results: There were 41 deep infections and 13 superficial. The average cost for the 54 patients for the in hospital treatment of infection was $41,215. The cost of treating a superficial infection with antibiotics alone averaged $17,663. The average cost of a two stage revision procedure for deep periprosthetic infection was $79,623. Assuming a hospital volume of 150 cases per year, the use of prophylactic intravenous antibiotics, the use of laminar flow and the combined use of antibiotics and laminar flow were significantly cost effective. The addition of antibiotic loaded cement was marginally cost ineffective in combination with either or both of intravenous antibiotics or laminar flow. Conclusion: The in hospital costs for the treatment of infection after TJR in the Australian setting have been addressed for the first time. Past studies have underestimated the cost of treatment. With this information, we have shown that the combinations of laminar flow and intravenous antibiotic for prophylaxis against infection in TJR are justified on a purely financial cost benefit basis


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_18 | Pages 13 - 13
1 Nov 2017
Dalgleish S Nicol G Faulkner A Sripada S
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Laminar airflow systems are universal in current orthopaedic operating theatres and are assumed to be associated with a lower risk of contamination of the surgical wound and subsequent early infection. Evidence to support their use is limited and sometimes conflicting. We investigated whether there were any differences in infection rates (deep and superficial) between knee and hip arthroplasty cases performed in non-laminar and laminar flow theatres at 10 year follow-up. Between 2002 and 2006, 318 patients underwent knee and hip arthroplasty in a non-laminar flow theatre. Prospectively collected local arthroplasty audit data was collected including superficial and deep infection, revision for infection and functional outcomes. A cohort of patients from the same time period, who underwent knee and hip arthroplasty in a laminar flow theatre, were matched for age, sex, body mass index (BMI), operative approach, implant and experience of surgeon. Superficial infection rates were lower overall in the non-laminar flow theatre (2.2percnt; versus 4.7percnt;), with a significantly lower superficial infection rate for knee arthroplasty performed in the non-laminar flow theatre (2percnt; versus 6.9percnt;). The deep infection rates were similar (1.3percnt; vs 1.9percnt;) for both laminar and non-laminar flow theatre respectively. Revision rates for infection were similar between both groups (0.9percnt; in non-laminar flow theatre vs 0.3percnt; in laminar flow). Whilst the causes of post-operative surgical site infection are multifactorial, our results demonstrate that at long –term follow-up, there was no increased risk of infection without laminar flow use in our theatre


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_12 | Pages 8 - 8
1 Jun 2017
Moores T Chatterton B Khan S Harvey G Lewthwaite S
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Deep infection occurs in 2–4% of lower limb arthroplasty resulting in increasing cost, co-morbidity and challenging revision arthroplasty surgery. Identifying the potential sources of infection helps reduce infection rates. The aim of our study is to identify the impact and potential for contamination of our hands and gowns whilst scrubbing using SSHS. A colony-forming unit (CFU) is a pathogenic particle of 0.5 micrometers to 5 micrometers. Concurrent particle counts and blood agar exposure settle plates for 3 subjects and 1 alcohol cleaned mannequin; testing a standard arthroplasty hood, a SSHS with and without the fan on for a 2 minute exposure to represent scrubbing time. Microbiological plates were incubated using a standard protocol by our local microbiology department. All SSHS were positive for gram-positive cocci with a mean colony count of 410cfu/m. 2. Comparing background counts for laminar flow (mean 0.7 particle/m. 3. ; 95% CI 0–1.4) versus scrub areas (mean 131.5 particle/m3; 95% CI 123.5–137.9; p=0.0003), however neither grew any CFU's with a 2-minute exposure. For the mannequin, the only significant result was with the fan on with a 1.5× increase in the particle count (p=0.042) and a correlating positive organism (13CFU/m. 2. ). With human subjects, however, the particle count increased by 3.75× the background count with the fan on (total p=0.004, CFU p=0.047) and all had positive cultures, mean 36 CFU/m. 2. There were no positive cultures with the standard arthroplasty hood or the SSHS with no fan on. If repeated in laminar flow, there was only a statistically significant increase with the fan on (p=0.049), but with negative cultures following a 2-minute exposure. Sterile gloves and gowns can be contaminated when scrubbing with the SSHS fan on. We recommend having the fan switched off when scrubbing until the hood and gown is in place, ideally in a laminar flow environment


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_13 | Pages 59 - 59
1 Mar 2013
Ayyaswamy B Hasan S An A Gulerl A
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The light handle can be a major source of contamination in operation theatres where surgeries are prolonged and light handles need to be manipulated multiple times. The light handle by sheer size can obstruct laminar flow and cause eddy currents and can cause bacterial deposition on light handle which in turn can contaminate light handles. A study of light handle contamination was done from November 2010 to December 2010 at Blackpool Victoria hospital from swabs taken from light handles during preoperative, intra operative and post operative period from a single laminar flow operating theatre. A total of 40 cases were selected for study. Most of our cases were primary hip and knee replacement. The swabs were cultured into blood agar /mcconkey medium and incubated for 48 hours at 37 degree Celsius. None of the swabs showed any bacterial contamination which shows light handle is not a source of intraoperative contamination. Our trial gives a point estimate of 0% contamination rate, upper limit of the 95% confidence interval of the probability of contamination as 7.5%. we conclude that light handle is not a source of contamination in operation theatres and hence no need to change gloves every time we manipulate light handle


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 482 - 482
1 Sep 2009
Boswell MAJ Greenough C
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Introduction: Surgical Site Infection (SSI) in spinal surgery at the James Cook University Hospital was investigated and compared with the published rates of 1–12%. Variables of instrumentation, laminar air flow, duration of operation, and blood units transfused in the first 48 hours were examined. Methods: 556 spinal operations were carried out in 2005–6. 147 of these involved the use of instrumentation. Infections were defined as positive wound or blood cultures. The duration of surgery, presence of laminar air flow and units of blood transfused were recorded. Statistical analysis was performed using the Fisher’s Exact Test. Results: Nine cases of SSI were identified in the 147 instrumented spinal operations in comparison to Zero in the 409 non-instrumented patients (p < 0.0001). The mean duration of instrumented surgery was 4 hours 19mins. The infection rates for operation duration < 5 h versus operation duration > 5 h (3/96 Vs 6/51) were not statistically significant (p = 0.065). Of the 147 instrumented spinal operations, 8 of 117 operations performed in a laminar air flow system and 1 of 30 performed without laminar air flow were infected (p = 0.69). Infection rates for those patients transfused < 2 units (4/85) were not significantly different to those in patients transfused > 2 units (5/62), p = 0.49. Conclusion: The rate of SSI at the James Cook University Hospital in instrumented spinal surgery was 6%. SSI in spinal surgery was heavily influenced by instrumentation, but was not reduced by laminar airflow. Duration of operation and number of units of blood transfused were not significant factors


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 101 - 101
1 Feb 2003
Sharp RJ Chesworth T Fern ED
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Patient warming systems are used routinely to prevent hypothermia under anaesthetic, the benefits of which have been clearly shown in the anaesthetic literature. We were concerned that since these systems take ‘dirty’ air from floor level and distribute it over the patient, bacterial counts could be increased. Also, airflow under the blanket itself could disturb the patients’ own skin cells and thereby influence bacterial counts. With slit air sampling we analysed air quality at the simulated operative site by passing a known volume of air over an agar plate (tryptone glucose yeast). Using probability curves we were able to calculate the volume of air required to detect 1 colony forming unit (CFU) per m³ with 97% confidence. All tests were performed in an ultra clean air laminar flow theatre. We assessed the effect of varying degrees of skin shedding under the warming blanket using volunteer patients with Psoriasis. We also simulated activity outside the lamina flow to determine whether counts on the table were influenced. No colonies were grown in any of the study groups. Plates exposed outside the laminar flow area at floor level showed a relatively high level of contamination. We therefore conclude that the WarmTouch warming system does not influence bacterial counts at the operative site in ultraclean air ventilated theatres