Background:. The aim of this study was to investigate the outcome after ACL reconstruction between a group of patients receiving a standardized supervised physiotherapy guided rehabilitation program and a group of patients who followed an un-supervised, home-based rehabilitation program. Methods:. 40 patients with isolated anterior cruciate ligament injuries were allocated to either a supervised physiotherapy intervention group or home-based exercise group. Patients were investigated by an independent examiner pre-operative, 3, 6, 9 and 12 months post-surgery using the following outcome measures: Lysholm Score and Tegner Activity Scale, functional hopping tests, isometric and isokinetic strength assessments. Results:. Both groups improved significantly (p=0.01–0.04) following 12 months after surgery. The median Lysholm score increased from 57 (34–90) to 94 (90–100) in the supervised group and 60 (41–87) to 97 (95–100) in the unsupervised group. The median Tegner Activity Scale increased from 3 (2–8) to 6 (3–8) in the supervised group and 4 (2–8) to 5 (3–10) in the unsupervised group. The combined mean symmetry indices for the hopping tests improved from 77.3+ 18.7 to 86.8+11.1 (supervised) and from 78.1+30.5 to 88.3+10.9 (unsupervised). Isometric and isokinetic strength symmetry indices for knee extension improved from 68.9+23.5 to 82.8+11.9 resp. 63.7+22.8 to 82.7+15.1 in the supervised group and from 73.6+20.5 to 76.5+17.9 resp. 69.5+24.3 to 76.9+16.9 in the unsupervised group. Eccentric strength symmetry indices for knee extension improved from 67.9+27.7 to 87.8+6.8 in the supervised group and from 71.3+17.8 to 82.6+15.6 in the unsupervised group. Conclusion:. This study could not demonstrate a benefit in a rehabilitation program supervised by a physiotherapist in our population compared to an unsupervised cohort