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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_8 | Pages 38 - 38
10 May 2024
Zhu M Mayo C Rahardja C Seow MY Young S
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Aims. Using the Australian and New Zealand Hip Fracture Registry (ANZHFR) data, this study aimed to identify patient, fracture, and management factors associated with survival, mobility and residential status at 120 days. This will allow future interventions to target modifiable risk factors to improve the overall care of patients with hip fractures. Methods. All NZ patients from 2018 – 2020 were included. Baseline demographics, management factors, and outcomes were recorded. Key outcomes were change in walking status, residential status and survival at 120 days. Univariate analysis was performed to compare differences in demographics, surgical and management factors for the key variables. Multivariate analysis was conducted to identify factors independently associated with outcomes. Results. Data from 9432 patients were analysed. The average age was 82.8 years (SD 9.8). 70.3% were females. 39.5% of patients were cognitively impaired on admission, 71.4% were from their own residence. At 120 days post injury, 10.9% (1029) had died 1029 (10.9%), 15.3% (1034) had a decrease in their residential status, 44.9% (2966) had a reduction in walking ability. On multivariate analysis; older age (RR1.1/yr, p<0.001), male sex (RR1.7, P<0.001), cognitive impairment (RR2.2, p<0.001) and ASA>3 (RR3.7, p=0.015) were risk factors for death. Similarly, increasing age (RR1.1 per year, p<0.001), cognitive impairment (RR1.2, p=0.04) and ASA>3 (RR2.9, p=0.047) were significant risk factors for worsening residential status. Decreasing mobility was associated with extracapsular fractures (RR1.4, p=0.01). After adjustment for demographics, ASA and fracture type, performing total hip arthroplasty was preventative for both worsening residential status (RR0.23, p<0.001) and decreasing walking ability (RR 0.21, p<0.001). There was no significant survival, functional or revision differences for other fixation types. Conclusion. There is a significant decline in walking ability post hip fracture which may be a key contributor to long-term morbidity. The benefits of THA in preserving mobility and independence should be further investigated. Additional discharge planning and multi-disciplinary team input are likely required for high-risk patients of older age, with cognitive impairment and extracapsular fractures


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_4 | Pages 14 - 14
3 Mar 2023
Mehta S Williams L Bhaskar D
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Introduction. Neck of femur (NoF) fractures have an inherent 6.5% 30-day mortality as per National hip fracture database(2019). Several studies have demonstrated a higher mortality rate in covid positive NoFs but have been unable to demonstrate whether there are risk factors that contribute to the risk of mortality in this patient group or whether COVID is solely responsible for the higher mortality. Aims. To assess risk factors that are concurrently present in a fracture NoF cohort that may contribute to higher mortality in COVID positive patients. Methods. A cross sectional, retrospective study was performed for a period of 1 year starting from 1st March 2020. All surgically treated neck of femur fracture patients having an isolated intra/extracapsular fracture were included in the study. Data fields recorded- patient demographics, date and time of admission, ward discharge, surgery, mode of surgery (fixation/arthroplasty), prehospital AMTS score, residential status and mobility, ASA grade as per anaesthetist's records, date of death (if deceased), cause of death (as per death certificate/ postmortem / coroner's report). Analysis of mortality was carried out by creating a matched comparison group for each risk factor as well as some combinations. Results. 344 patients were surgically treated for a neck of femur fracture in our DGH during the period of 1st March 2020 to 28th February 2021. 46 patients did not receive a COVID swab (reasons unknown) and were excluded from the study. 35 patients had a COVID-19 RT PCR positive test during their hospital stay and 264 patients remained negative. There were 12 deaths in COVID positive patients (34%) and 53 deaths in COVID negative patients (20%) within the time frame of the study. For each risk factor matched group COVID was seen to confer higher mortality in general. There was no mortality in ASA 1 or 2 patients. Mortality rates in matched groups for age and ASA revealed 23.8% mortality in COVID positive as opposed to 17.3% in COVID negative for ASA 3 and 33.3% mortality in COVID positive vs. 28% in ASA 4. 11 out of the 12 COVID positive patients who died had an AMTS score >6. No correlation was seen between COVID positive deaths and preinjury residential status, type of fracture or surgery offered, or preinjury mobility. The average length of hospital stay was much higher for COVID positive patients (19.5days) as compared to 9.5 days for COVID negative patients. Conclusion. Matched group analysis show that there is a 37.5% increase in COVID positive neck of femur fracture mortality in ASA 3 patients, the same number falls to 17.8% for ASA 4 patients. These figures are much lower compared to other studies in the UK. There is a need to understand the real cause of death in this subset and to improve death certification so that we can differentiate between patients whose mortality is ‘due to’ or ‘With’ COVID


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_3 | Pages 5 - 5
1 Apr 2019
Gogi N Azhar S Dimri R Chakrabarty G
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Fracture neck of femur (NOF) in elderly is a serious debilitating injury and has been presenting in increasing proportions. Some of these patients are unfortunate to come back with a contralateral injury. We attempted at looking into the incidence of these episodes in a cohort attending our trust and compared various parameters. We retrospectively assessed our hospital theatre data for fracture NOF in patients over 60 years in the last 3 years. We reviewed their demographics, mode of injury, time to contralateral injury, incidence of any other insufficiency fracture, operative procedure and any complications. There were 1435 patients who underwent surgery for fracture NOF over the 3 years. Forty-three of these had bilateral fractures. Females had 3 times more incidence as compared to males; average age at first injury was 84 years and at contralateral side was 85 years. Time between the two injuries ranged from 20 to 855 days (Median 242 days). Almost equal incidence of intra / extracapsular fractures was noted. Contralateral fracture pattern (Intra vs Extracapsular) for the was similar in 34 patients. Twelve patients had an associated insufficiency fracture. Fracture NOF in elderly is a rising epidemic. Only 3% of these patients suffer a contralateral fracture NOF which usually occurs within a year. The fracture pattern is frequently similar to the first fracture in and hence similar implants have been used. Only 21% patients were on bone protection medications. It is rather difficult to identify this small group and hence prevent a second contralateral incident


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_12 | Pages 23 - 23
1 Mar 2013
Naqvi S Iqbal S Braithwaite I Banim R Reynolds T
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Hip fractures accounts to about 86000 cases per annum in UK. AP and Lateral radiographs form an essential investigation in planning the management of these fractures. Recently it has been suggested that lateral view doesn't provide any additional information in majority of the cases. We looked retrospectively at 25 consecutive radiographs with intracapsular and extracapsular fracture neck of femur each presenting to our department between May 2010 and January 2011. These radiographs were put on the CD in 2 folders as AP and Lateral. It was reviewed by 2 Observers who suggested their preferred treatment. The results were compared for the intra observer agreement to assess the necessity of the lateral view of the radiographs. We also compared the treatment options with the gold standard and looked at the interobserver agreement. Of the 50 set of radiographs that were reviewed, Observer 1 had disagreed with himself on one occasion (98%agreement) compared to the Observer 2 who had two disagreements (96% agreement). When analyzing the intracapsular fractures, we found 100% agreement of OBSERVER 1 with himself when proposing treatment on AP and Lateral View. Whereas, OBSERVER 2 had only one disagreement. It gave us a Free marginal kappa value of more than 0.70 indicating excellent agreement. One difference doesn't have any statistical significance. In the extracapsular fractures, Kappa values ranged from 0.413 to 0.88. OBSERVER 1 did change his opinion after reviewing the lateral view but generally had good outcome (K=0.88). Whereas, the opinion of OBSERVER 2 was unaffected by the Lateral view. The X-ray diagnoses by OBSERVER 1 and OBSERVER 2 had only moderate agreement (K=0.52 (AP) and 0.57 (Lat). Comparing the observer opinion to the gold standard (operation performed) showed moderate agreement both on AP and Lateral view (OBSERVER 1 AP and Lat both K=0.64, OBSERVER 2 AP and Lat both K=0.41). The Lateral view failed to change the opinion of the observers (K > 0.7) but there was moderate to excellent agreement between the observers and observer vs operation (The Gold Standard) with kappa value of more than 0.52. We feel that the Lateral view doesn't make any difference in most of the cases as shown by a good intra-observer agreement. However, we cannot completely rule out their importance and they should be performed in occult fractures, pathological fractures, fractures extending into the shaft, young patients, and on the request of physician


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_10 | Pages 60 - 60
1 Jun 2018
MacDonald S
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Patients with painful metal-on-metal bearings presenting to the orthopaedic surgeon are a difficult diagnostic challenge. The surgeon must go back to basic principles, perform a complete history and physical exam, obtain serial radiographs and basic blood work (ESR, CRP) to rule out common causes of pain and determine if the pain is, or is not, related to the bearing. The Asymptomatic MoM Arthroplasty: Patients will present for either routine follow up, or because of concerns re: their bearing. It is important to emphasise that at this point the vast majority of patients with a MoM bearing are indeed asymptomatic and their bearings are performing well. The surgeon must take into account: a) which specific implant are they dealing with and what is its track record; b) what is the cup position; c) when to perform metal ion testing; d) when to perform further soft tissue imaging (MARS MRI, Ultrasound); e) when to discuss possible surgery. Painful MoM THA causes not related to the bearing couple: These can be broken down into two broad categories. Causes that are Extrinsic to the hip include: spine, vascular, metabolic and malignancy. Causes that are Intrinsic to the hip can either be Extracapsular (iliopsoas tendonitis and trochanteric bursitis) or Intracapsular (sepsis, loosening, thigh pain, prosthetic failure). Painful MoM THA causes related to the bearing couple: There are now described a number of possible clinical scenarios and causes of pain that relate to the metal-on-metal bearing couple itself: a) local hypersensitivity reaction without a significant soft tissue reaction; b) local hypersensitivity reaction with a significant soft tissue reaction; c) impingement and soft tissue pain secondary to large head effect. Metal ions: obtaining serum, or whole blood, cobalt and chromium levels is recommended as a baseline test. However, there is no established cutoff level to determine with certainty if a patient is having a hypersensitivity reaction. A 7 parts per billion cutoff has been suggested. This gives high specificity, but poor sensitivity. Metal ions therefore can be used as a clue, and one more test in the workup, but cannot be relied upon in isolation to make a diagnosis. MARS MRI: a useful tool for demonstrating soft tissue involvement, but there are many painless, well-functioning MoM implants that have soft tissue reactions, that don't require a revision. In the painful MoM hip an MRI, or ultrasound, is recommended to look for soft tissue destruction or a fluid-filled periprosthetic lesion (pseudotumor). Significant soft tissue involvement is concerning and is commonly an indication for revision in the painful MoM hip. Treatment: management of the painful MoM hip is directly related to the etiology of the pain. Unique to MoM bearing is the issue of pain secondary to a local hypersensitivity reaction. All above tests should be utilised to help determine the best course of action in any individual patient. The painful MoM bearing, that is demonstrating significant soft tissue involvement is a concerning scenario. Earlier revision, to prevent massive abductor damage, would seem prudent for these patients. The painful MoM bearing with no significant soft tissue changes can probably be followed and reviewed at regular intervals. If the pain persists and is felt to be secondary to a hypersensitivity reaction, then revision is really the only option, although the patient must be cautioned regarding the unpredictable nature of the pain relief


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_22 | Pages 40 - 40
1 May 2013
MacDonald S
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Pain following total hip arthroplasty is a relatively rare event. Several series place the incidence of some degree of pain post THA at approximately 5%. A systematic approach to determining etiology will direct treatment. Hip pain can be categorised as:. Extrinsic to the Hip. –. Spine +/− radiculopathy. –. Vascular disease. –. Metabolic (Paget's). –. Malignancy. Intrinsic to the Hip. Intracapsular/Implant. Loosening. Sepsis. Prosthetic failure. Osteolysis. Instability. Thigh pain. Stem tip pain. Hypersensitivity/ALVAL. Extracapsular. Iliopsoas tendonitis. Snapping Hip. Trochanter problems (bursitis). Heterotopic ossification. A full history and appropriate physical exam will direct the clinician. The use of routine radiographs, blood tests, and special tests (i.e., blood metal ions, advanced imaging techniques) will be discussed I detail


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_15 | Pages 90 - 90
1 Aug 2017
MacDonald S
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Metal-on-metal bearings (MoM) saw an increase in global utilisation in the last decade. This peaked in 2008 in the US, with approximately 35% of bearings being hard-on-hard (metal-on-metal, or ceramic-on-ceramic). Beginning in 2008, reports began to surface regarding local soft tissue reactions and hypersensitivity to MoM bearings. A major implant manufacturer recalled a resurfacing device in 2010 after national joint registries demonstrated higher than expected revision rates. Patients with painful MoM bearings are a difficult diagnostic challenge. The surgeon must go back to basic principles, perform a complete history and physical exam, obtain serial radiographs and basic blood work (ESR, CRP) to rule out common causes of pain and determine if the pain is, or is not, related to the bearing. The Asymptomatic MoM Arthroplasty: Patients will present for either routine follow up, or because of concerns regarding their bearing. It is important to emphasise that at this point the vast majority of patients with a MoM bearing are indeed asymptomatic and their bearings are performing well. The surgeon must take into account: a) which specific implant are they dealing with and what is its track record; b) what is the cup position; c) when to perform metal ion testing; d) when to perform further soft tissue imaging (MARS MRI, Ultrasound); e) when to discuss possible surgery. Painful MoM THA causes not related to the bearing couple: These can be broken down into two broad categories. Causes that are Extrinsic to the hip include spine, vascular, metabolic and malignancy. Causes that are Intrinsic to the hip can either be Extracapsular or Intracapsular. Painful MoM THA causes related to the bearing couple: There are now described a number of possible clinical scenarios and causes of pain that relate to the MoM bearing couple itself: A) Local hypersensitivity reaction without a significant soft tissue reaction; B) Local hypersensitivity reaction with a significant soft tissue reaction; C) Impingement and soft tissue pain secondary to large head effect. Factors related to a hypersensitivity reaction: Some patients, and prostheses, seem to be at a higher risk of developing issues following a MoM bearing, although our understanding of the interplay of these factors is still in evolution: patients at risk include all women and patients with smaller component sizes. Implant factors play a role with some implants having higher wear rates and being more prone to corrosion. Special tests: There is ongoing confusion related to the relative value of the various special tests that patients with a painful MoM undergo. A) Metal Ions - obtaining serum, or whole blood, cobalt and chromium levels is recommended as a baseline test. However, there is no established cutoff level to determine with certainty if a patient is having a hypersensitivity reaction. Metal ions therefore can be used as a clue, but cannot be relied upon in isolation to make a diagnosis. B) MARS MRI - a useful tool for demonstrating soft tissue involvement, but there are many painless, well-functioning MoM implants that have soft tissue reactions, that don't require a revision. In the painful MoM hip an MRI, or ultrasound, is recommended to look for soft tissue destruction or a fluid-filled periprosthetic lesion (pseudotumor). Significant soft tissue involvement is concerning and is commonly an indication for revision in the painful MoM hip. C) CT imaging - can be utilised to help determine cup position and combined anteversion, however, plain radiographs can give a rough estimate of this as well, so routine CT scan evaluations are not currently recommended. The painful MoM bearing, that is demonstrating significant soft tissue involvement is a concerning scenario. Earlier revision, to prevent massive abductor damage, would seem prudent for these patients. The painful MoM bearing with no significant soft tissue changes can probably be followed and reviewed at regular intervals. If the pain persists and is felt to be secondary to a hypersensitivity reaction, then revision is really the only option, although the patient must be cautioned regarding the unpredictable nature of the pain relief


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 38 - 38
1 Sep 2012
Harrison T Robinson P Cook A Parker M
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The purpose of the study was to identify factors that affect the incidence of deep wound infection after hip fracture surgery. Data from a hip fracture database of 7057 consecutively treated patients at a single centre was used to determine the relationship between deep wound sepsis and a number of factors. Fisher's exact test and the unpaired T test were used. All patients were initially followed up in a specialist clinic. In addition a phone call assessment was made at one year from injury to check that no later wound healing complications had occurred. There were 50 cases of deep infection (rate of 0.7%). There was no significant difference in the rate of deep sepsis with regards to the age, sex, pre-operative residential status, mobility or mental test score of the patient. Specialist hip surgeons and Consultants have a lower infection rate compared with surgeons below Consultant grade, p=0.01. The mean length of anaesthesia was longer in the sepsis group (76minutes) compared to the no sepsis group (65minutes), this was significant, p=0.01. The patient's ASA grade and fracture type were not significant factors. The rate of infection in intracapsular fractures treated by hemiarthroplasty was significantly greater than those that had internal fixation, p=0.001. The rate of infection in extracapsular fractures fixed with an extra-medullary device was significantly greater than those fixed with an intra-medullary device, p=0.021. The presence of an infected ulcer on the same leg as the fracture was not associated with a higher rate of deep infection. In conclusion we have found that the experience (seniority) of the surgeon, the length of anaesthesia and the type of fixation used are all significant factors in the development of deep sepsis. These are all potentially modifiable risk factors and should be considered in the treatment of hip fracture patients


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_19 | Pages 1 - 1
1 Apr 2013
Kotwal R Moideen AN Jones S
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Introduction. The reverse obliquity fractures of the proximal femur are anatomically and mechanically different from most intertrochanteric fractures. These fractures are complex and very difficult to treat. To evaluate the results of the treatment of reverse obliquity intertrochanteric fractures with cephalomedullary nails. Materials and Methods. Between 2005 and 2009, 1179 extracapsular fractures of the proximal femur were treated at our institution. Retrospective review of these x-rays identified 59 patients with reverse obliquity fracture pattern. We analysed our results of cephalomedullary nailing of these complex fractures and evaluated factors responsible for failure of fixation. Results. Of the 59 patients with reverse oblique fracture pattern, one patient was treated with DHS, and two other patients didn't have post-operative x-rays and therefore were excluded from the study. Of the remaining 56 patients treated with cephalomedullary nails, forty eight were treated with gamma nails, five with PFNA and three with ATN. There were 40 females and 16 males with median age of 81.3 years (17–103 years). Six of the fifty six (10.7%) failed to heal or had failure of fixation. The failure rate was four of forty eight for the gamma nails, one of five of the PFNA and one of three of ATN. One of thirty seven (2.7%) of anatomically reduced fractures and five of nineteen (26.3%) of non-anatomically reduced fractures had failure of treatment (p = 0.01). Three of thirteen (23.1%) with femoral medialisation and three of forty three (6.9%) without femoral medialisation had failure of treatment (p = 0.13). Four of forty four (9.1%) with avulsed lesser trochanter and two of twelve (16.6%) without avulsion had failure of treatment (p = 0.59). Three of thirty seven (8.1%) with tip apex distance (TAD) of less than twenty and three of nineteen (15.7%) with TAD more than twenty had failure of treatment (p = 0.65). Conclusion. Inspite of the recent advances in the methods of internal fixation available to surgeons, reverse obliquity intertrochanteric fractures continue to be a challenge for orthopaedic surgeons. In our study, although poor fracture reduction was observed to be the only significant factor associated with a high failure rate, femoral medialisation and tip apex distance of more than 20 had a high association with poor outcome


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIII | Pages 14 - 14
1 May 2012
Lam P
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Ankle sprains have been shown to be the most common sports related injury. Ankle sprain may be classified into low ankle sprain or high ankle sprain. Low ankle sprain is a result of lateral ligament disruption. It accounts for approximately 25% of all sports related injuries. The ankle lateral ligament complex consists of three important structures, namely the anterior talofibular ligament (ATFL), calcaneofibular ligament (CFL) and posterior talofibular ligament (PTFL). The ATFL is the weakest and most easily injured of these ligaments. It is often described as a thickening of the anterolateral ankle capsule. The ATFL sits in a vertical alignment when the ankle is plantarflexed and thus is the main stabiliser against an inversion stress. T he CFL is extracapsular and spans both the tibiotalar and talocalcaneal joints. The CFL is vertical when the ankle is dorsiflexed. An isolated injury to the CFL is uncommon. Early diagnosis, functional management and rehabilitation are the keys to preventing chronic ankle instability following a lateral ligament injury. Surgery does not play a major role in the management of acute ligament ruptures. Despite this up to 20% of patients will develop chronic instability and pain with activities of daily living and sport especially on uneven terrain. Anatomic reconstruction for this group of patients is associated with 90% good to excellent results. It is important that surgery is followed by functional rehabilitation. One of the aims of surgery in patients with recurrent instability is to prevent the development of ankle arthritis. It should be noted that the results of surgical reconstruction are less predictable in patients with greater than 10 year history of instability. Careful assessment of the patient with chronic instability is required to exclude other associated conditions such as cavovarus deformity or generalised ligamentous laxity as these conditions would need to be addressed in order to obtain a successful outcome. High ankle sprain is the result of injury to the syndesmotic ligaments. The distal tibiofibular joint is comprised of the tibia and fibula, which are connected by anterior inferior tibiofibular ligament, interosseous ligament and the posterior inferior tibiofibular ligament (superficial and deep components). The mechanism of injury is external rotation and hyperdorsiflexion. High index of suspicion is required as syndesmotic injuries can occur in association of low ankle sprains. The clinical tests used in diagnosing syndesmotic injuries (external rotation, squeeze, fibular translation and cotton) do not have a high predictive value. It is important to exclude a high fibular fracture. Plain radiographs are required. If the radiograph is normal then MRI scan is highly accurate in detecting the syndesmotic disruption. Functional rehabilitation is required in patients with stable injuries. Syndesmotic injuries are often associated with a prolonged recovery time. Accurate reduction and operative stabilisation is associated with the best functional outcome in patients with an unstable syndesmotic injury. Stabilisation has traditionally been with screw fixation. Suture button syndesmosis fixation is an alternative. Early short-term reviews show this alternate technique has improved patient outcomes and faster rehabilitation without the need for implant removal


The Bone & Joint Journal
Vol. 103-B, Issue 4 | Pages 782 - 787
3 Apr 2021
Mahmood A Rashid F Limb R Cash T Nagy MT Zreik N Reddy G Jaly I As-Sultany M Chan YTC Wilson G Harrison WJ

Aims

Despite the COVID-19 pandemic, incidence of hip fracture has not changed. Evidence has shown increased mortality rates associated with COVID-19 infection. However, little is known about the outcomes of COVID-19 negative patients in a pandemic environment. In addition, the impact of vitamin D levels on mortality in COVID-19 hip fracture patients has yet to be determined.

Methods

This multicentre observational study included 1,633 patients who sustained a hip fracture across nine hospital trusts in North West England. Data were collected for three months from March 2020 and for the same period in 2019. Patients were matched by Nottingham Hip Fracture Score (NHFS), hospital, and fracture type. We looked at the mortality outcomes of COVID-19 positive and COVID-19 negative patients sustaining a hip fracture. We also looked to see if vitamin D levels had an impact on mortality.