Aims. A review of the literature on elbow replacement found no consistency in the clinical outcome measures which are used to assess the effectiveness of interventions. The aim of this study was to define core outcome domains for elbow replacement. Methods. A real-time Delphi survey was conducted over four weeks using outcomes from a scoping review of 362 studies on elbow replacement published between January 1990 and February 2021. A total of 583 outcome descriptors were rationalized to 139 unique outcomes. The survey consisted of 139 outcomes divided into 18 domains. The readability and clarity of the survey was determined by an advisory group including a patient representative. Participants were able to view aggregated responses from other participants in real time and to revisit their responses as many times as they wished during the study period. Participants were able to propose additional items for inclusion. A Patient and Public Inclusion and Engagement (PPIE) panel considered the consensus findings. Results. A total of 45 respondents completed the survey. Nine core mandatory domains were identified: ‘return to work or normal daily role’; delivery of care was measured in the domains ‘patient satisfaction with the outcome of surgery’ and ‘would the patient have the same operation again’; ‘pain’; ‘revision’; ‘elbow function’; ‘independence in activities of daily living’; ‘health-related quality of life’; and ‘adverse events’. ‘Elbow range of motion’ was identified as important by consensus but was felt to be less relevant by the PPIE panel. The PPIE panel unanimously stated that pain should be used as the primary outcome domain. Conclusion. This study defined core domains for the clinical outcomes of elbow replacement obtained by consensus from patients, carers, and healthcare professionals. Pain may be used as the primary outcome in future studies, where appropriate. Further work is required to define the instruments that should be used. Cite this article: Bone Joint J 2024;106-B(11):xxx–xxx

Aims. Arthroplasties of the elbow, including total elbow arthroplasty, radial head arthroplasty, distal humeral hemiarthroplasty, and radiocapitellar arthroplasty, are rarely undertaken. This scoping review aims to outline the current research in this area to inform the development of future research. Methods. A scoping review was undertaken adhering to the Joanna Briggs Institute guidelines using Medline, Embase, CENTRAL, and trial registries, limited to studies published between 1 January 1990 and 7 February 2021. Endnote software was used for screening and selection, and included randomized trials, non-randomized controlled trials, prospective and retrospective cohort studies, case-control studies, analytical cross-sectional studies, and case series of ten or more patients reporting the clinical outcomes of elbow arthroplasty. The results are presented as the number of types of studies, sample size, length of follow-up, clinical outcome domains and instruments used, sources of funding, and a narrative review. Results. A total of 362 studies met the inclusion criteria. Most were of total elbow arthroplasty (246; 68%), followed by radial head arthroplasty (100; 28%), distal humeral hemiarthroplasty (11; 3%), and radiocapitellar arthroplasty (5; 1%). Most were retrospective (326; 90%) and observational (315; 87%). The median sample size for all types of implant across all studies was 36 (interquartile range (IQR) 21 to 75). The median length of follow-up for all studies was 56 months (IQR 36 to 81). A total of 583 unique outcome descriptors were used and were categorized into 18 domains. A total of 105 instruments were used to measure 39 outcomes. Conclusion. We found that most of the literature dealing with elbow arthroplasty consists of retrospective observational studies with small sample sizes and short follow-up. Many outcomes have been used with many different instruments for their measurement, indicating a need to define a core set of outcomes and instruments for future research in this area. Cite this article: Bone Joint J 2022;104-B(10):1148–1155

The aim of the New Zealand Elbow Arthroplasty Register is to evaluate the provision of elbow arthroplasty across the entire country by both recording accurate technical information and measuring the clinical outcomes of all elbow replacements performed in New Zealand. An initial form is completed at the time of surgery which includes details of the patient, surgical indications, the surgical procedure, the implant and the operating surgeon. Six months following surgery, all registered patients are asked to complete a questionnaire to measure the pain and function of the replaced elbow and to comment on any post operative complications. Data from 99 consecutive primary and 16 revision elbow arthroplasties was prospectively collected from January 2000 till December 2003. Rheumatoid arthritis was the commonest indication (63 cases) and the outcome was significantly better than for trauma and osteoarthritis. The Coonrad-Morrey was the most commonly used prosthesis (86 cases) followed by the Kudo (eight cases) and the Acclaim (five cases). 21 surgeons performed elbow arthroplasty during the study period but only five performed on average more than one case per year. Their results at six months were statistically superior to those provided by other surgeons. The number of complications reported by patients and the revision rate within the study period was low. An infection was seen in only two patients. The New Zealand Elbow Arthroplasty Register has become a robust method of assessment of the provision of elbow arthroplasty within the country. Our findings support the idea that elbow arthroplasty should not be performed by general orthopaedic surgeons on an occasional basis

We divided 309 patients with an inflammatory arthritis who had undergone primary elbow replacement using the Souter-Strathclyde implant into two groups according to their age. The mean follow-up in the older group (mean age 64 years) was 7.3 years while in the younger patients (mean age 42 years) it was 12 years. Survivorship for three different failure end-points (revision, revision because of aseptic loosening of the humeral component, and gross loosening of the humeral implant), was compared in both groups. Our findings showed that there was no significant difference in the incidence of loosening when young rheumatoid patients were compared with an older age group

Introduction: The design of the GSB III elbow arthroplasty has essentially remained unchanged since 1978 until recently. Because of observations of aseptic loosening of the ulnar component, the ulnar stem was changed in an excentric curved shape. The aim of the present study was to assess the clinical and radiographic outcome after more than 2 years of follow up with the new ulnar stem shape. Patients and methods: Between january 2000 and august 2002, 34 patients had undergone 36 total elbow replacements with the GSB III device with a new curved ulnar shape. Nineteen patients (20 elbows) underwent the operation for the first elbow arthroplasty and 16 patients underwent revision surgery. The mean follow up was 35 months (R: 25–49). The subjective satisfaction and pain intensity were assessed. Clinical exam recorded range of motion and strength. Radiographs were analysed for implant loosening and osteolysis. Results: There was a significant improvement of the average range of motion in flexion-extension from pre-operative 82degree to postoperative 105degree for all 36 elbows (t-test, p< 0,005). The 20 cases with primary elbow arthroplasty showed a significant improvement in the average range of flexion-extension from 76degree to 106degree (t-test, p< 0,001). The subjective assessment for satisfaction averaged 93 per cent at the time of follow up. For the 16 patients with revision elbow arthroplasty, the average range of flexion-extension improved from 90degree to 103degree (p< 0,01). The mean subjective satisfaction rated at 94 per cent. One case showed a radiolucent line at the ulnar component which remained unchanged at follow up. There was no component loosening. Discussion: The new excentric curved ulnar component shows no case of component loosening in our series for primary and revision elbow arthroplasty after 2 years. The range of motion and patient satisfaction are promising

Objective:. Total elbow joint arthroplasty has limited longevity and is therefore not appropriate for younger rheumatoid arthritis patients. Arthroplasty using an inter-positional membrane may be another surgical option for this population. However, clinical results for joint arthroplasty using the inter-positional membrane have not traditionally been favorable because rheumatoid activity could not be controlled. Today, rheumatoid activity can be controlled with biologics; therefore, the utility of the inter-positional membrane procedure was re-evaluated. Methods:. An 8×6 cm sheet of fascia was detached from the patient's tensor fascia lata muscle to produce a JK membrane. The fascia was stretched on a frame and kept in a 2% chromic acid potassium solution for 24 hours. Then, the fascia was exposed to direct sunlight in order to reduce the dichromic acid. The fascia was washed out in running water for 24 hours and was then stored in phenol with the addition of 70% alcohol. Elbow arthroplasties were performed on three elbow joints in two young female patients. The first case had a significantly damaged right elbow joint with severe joint dysfunction. A JK membrane arthroplasty was done for the first case in 2003, when this patient was 34 years old. Biologics were administered with methotrexate after the surgery. The second case demonstrated bilateral ankylosed elbows due to idiopathic juvenile arthritis. Bilateral JK membrane arthroplasties were performed in 2010, when this patient was 32 years old. Several operative and manual manipulations were necessary in order to increase the range of motion following surgery. Biologics were administered with cyclosporine. Results:. Joint function was significantly improved in all three joints without pain after the JK membrane elbow arthroplasties. In case one, the JOA (Japan Orthopaedic Association) elbow score improved from 21 points before surgery to 85 points after surgery and active elbow flexion improved to 110 degrees following surgery. In case two, the JOA elbow score was 55 and 82 points in the right elbow and 52 and 83 points in left elbow before and after surgery, respectively. In case two, active flexion improved to 120 degrees for the right elbow and 110 degrees for the left elbow following surgery. RA was well controlled in both patients. Conclusion:. Elbow arthroplasty using an inter-positional membrane appears to be useful in young patients when RA activity is controlled with biologics

We report 5 cases of linked shoulder and elbow replacement (LSER) following failure of single-joint arthroplasty. Whilst total humeral replacement has been reported for treatment following resection for tumour we know of no reports of linked shoulder and elbow prostheses for arthropathy alone. Between May and December 2005, 2 patients with total elbow arthroplasty and 3 patients with total shoulder arthroplasty were revised to LSER for loosening of the long humeral stems or periprosthetic fracture. Custom-made prostheses were produced using computer-aided design and manufacture technology. There were no early complications including infection. All 5 patients reported early improvement of symptoms, with the ability to bear weight axially through the limb, restored. This technique avoids the problem of a stress riser between the stems of separate shoulder and elbow replacements and solves the problem of salvage of long-stemmed implants where no further humeral fixation is possible

Introduction. Cement pressurisation in the distal humerus is technically difficult due to the anatomy of the humeral intramedullary (IM) cavity. Conventional cement restrictors often migrate proximally or leak, reducing the effect of pressurisation during implantation. Theoretically with a better cement bone interdigitation, the longevity of the elbow replacement can be improved. The aim of this cadaveric study was to evaluate the usefulness of a novel technique for cementation. Method. Eight paired fresh frozen cadaveric elbows were randomly allocated to conventional cementing techniques or cementing using a paediatric foley catheter as a temporary restrictor. The traditional cementing technique consisted of canal preparation using irrigation, brushing and drying prior to cementation, with no use of a cement restrictor. The new technique involved same canal preparation but prior to cementation a size 8 foley catheter was introduced and the balloon inflated to act as a temporary cement restrictor. The humeri were cut into 10mm sections. Each slice was photographed and radiographed. This dual imaging technique was used to establish the best methodology for evaluation of cement penetration. Cement penetration was calculated as a ratio of the area of intra-medullary cavity occupied by the cement. Results. There was no significant difference between the photographic and radiographic method of measuring cement penetration. Cement penetration was significantly better in the foley catheter group (P = 0.002-0.037). The maximum penetration was observed in the most distal 2-5cm. Conclusion. The foley catheter technique consistently and significantly achieved a better cement interdigitation into the cancellous bone, without leaving a void in the cement. This study has demonstrated a new cementing technique for elbow arthroplasty, utilising a paediatric foley catheter as a temporary humeral intra-medullary plug, increasing cement pressurisation and restricting proximal cement migration. Future studies using this methodology will not require supplementation of photographs with radiographic analysis

A systematic review of the English language literature has suggested that the performance of linked and unlinked elbow replacement implants differ in terms of function, survival and mode of failure; however, in this review, only one comparative series using contemporary implants was identified. We have performed a cohort study of Kudo, Souter-Strathclyde and Coonrad-Morrey elbow replacements performed at a single centre by or under the direct supervision of a single Consultant shoulder and elbow surgeon to see if these findings were reflected in clinical practice. The first forty implantations in patients with Rheumatoid arthritis for each device have been reviewed with respect to surgical complications, elbow function and implant survival. The follow-up was shorter for the Coonrad-Morrey cohort. In terms of pain relief and range of motion, the performance of the implants was comparable. The mode of failure was different, with no dislocations/ instability seen with the linked Coonrad-Morrey implants. The loosening rate of the Coonrad-Morrey implants (both clinical and radiographic) was lower, albeit with a shorter follow-up period. The loosening rates seen in this series were higher than those previously reported in the English language literature. We conclude that the functional performance of the implants, at similar stages of the surgical learning curves, are similar in patients with Rheumatoid arthritis, but that use of a linked implant removes the risk of post-operative instability and may reduce the risk of the radiographic and clinical loosening

We present the results of 525 primary Souter elbow arthroplasties undertaken in 406 patients between 1982 and 1997. There were 372 women and 34 men with a mean age of 57 years; 119 patients had a bilateral procedure. The elbows were affected by chronic inflammatory disease, usually rheumatoid arthritis, which had been present for a mean of 24.7 years (2 to 70). In about 30% the joints were grossly destroyed with significant loss of bone. In 179 elbows the ulnar components were metal-backed and retentive; in the remaining 346, with better bone stock, non-retentive, all-polyethylene prostheses were used. Because of complications, 108 further operations were required in 82 patients. During the early years the incidence of complications was higher. Dislocation was the indication for 30 further procedures in 26 patients. Thirty patients underwent 33 revision procedures for aseptic loosening, 12 had 29 operations because of deep infection, two for superficial infection, and 14 further operations were done for other reasons. The cumulative rate of success, without aseptic loosening, five and ten years after surgery, was 96% and 85%, respectively

This study assesses long term performance of the Souter-Strathclyde elbow arthroplasty. From 1984 to 1999, 68 Souter-Strathclyde prostheses were inserted in 53 patients; nine patients died, one was lost and 38 (88%) had full clinical examination. Mean survival was 72 months (range 8 to 187), 25 elbows survived to 5-year follow up, with improvement in pain, motion, stability and function. Mayo score was satisfactory in 92% of all 68 elbows. Complications occurred in 13 elbows (19%) and 14 elbows were revised for instability (six), fracture (three), loosening (three) and intraoperative problems (two). Survivorship at 10 years was 74% (95% Confidence Interval ± 7. 7)

Introduction: Distal humeral fractures represent a constant challenge to the most experienced surgeon. This is the first report of the use of an unlinked prosthesis for the treatment of distal humeral fractures in elderly persons. Materials and Methods: From July 2000 to June 2001, 9 iBP elbow arthroplasties were performed in patients with acute fractures of the distal humerus. The average age of the group was 71 years. The mean interval between injury and TER was 11 days. The follow-up period averaged 12 months (range 5 to 16). Results: Functional outcome was evaluated with patient-completed questionnaires. All patients had a flexion contracture of the elbow ranging from 15 to 30 degrees. All patients were able to perform daily activities, pain relief was satisfactory and patient satisfaction was high. All elbows met the criteria for functional motion and were stable at the latest follow-up examination. There were no major complications such as dislocation, ulnar nerve dysfunction or deep infection. Conclusion: Unlinked non-congruous elbow arthroplasty when combined with a surgical exposure that allows proper soft tissue balance and instrumentation that enables correct positioning of the components can be a successful alternative in the management of acute distal humeral fractures in selected patients when conventional fixation is not a viable option

This paper describes the development, operative technique and results of an unconstrained total elbow arthroplasty. Forty-seven elbow replacements were carried out in 44 patients between 1974 and 1982. There was a high rate of loosening in the early condylar replacements. The results in patients with post-traumatic arthritis were poor. The later design employs an ulnar stem, with a humeral stem if the distal humeral bone stock is poor. When used in carefully selected patients with rheumatoid arthritis, pain is reduced significantly, stability and movement are preserved and function is improved

Introduction: In the evaluation of the major joints, self assessment tools have become wide spread aiming at a more precise quantification of joint function. Different tools have been developed for the elbow joint. However, there are only few data on the relationship between subjective self-assessment of joint function and objective measures. We developed a comprehensive assessment set for the evaluation of subjective elbow function and objective clinical findings and investigate long-term results after implantation of GSB III Elbow arthroplasties in a first study. The PREE-G was cross-culturally adapted, following the recommendations of the American Association of Orthopedic Surgeons. Material and Methods: 79 patients (56 female, 23 male, mean age 64 years) after elbow arthroplasty between 1984 and 1996 due to rheumatoid (59) or posttraumatic (20) arthritis underwent an assessment of the joint function using the PREE, the Short Form 36 (SF-36), the Disabilities of Arm, Shoulder, Hand (DASH)) and the modified American Shoulder and Elbow Surgeons (mASES) for a clinical evaluation. In 62 patients implantation was performed unilaterally and in 17 patients bilaterally, resulting in 96 elbow joints altogether. The mean follow up time was 11,2 years. Results: In the SF-36 score, the mean physical component scale (PCS) was worse (37,2 vs 41,7, p=0,004), the mean mental component scale (MCS) better (52,3 vs 50,3, p=0,092) than normative values of a German population. Subjective assessment by the PREE revealed a mean of 66,8, by the mASES of 63,1 and by the DASH of 56,5 points. Clinical examination resulted in a mean mASES score of 71,6 points. Comparison between the patients self assessment and the objective score revealed a significant correlation between the DASH (r=0,46, p< 0,001), PREE (p=0,54, p< 0,001) and mASES (r=0,60, p< 0,001) with the clinical mASES. In contrast, no significant correlation was found between the physical component scale (PCS) and mental component scale (MCS) of SF-36 and the clinical mASES. Also the patients assessment scores DASH, PREE and mASES showed a strong significant correlation among one another (r=0,74–0,92, p< 0,001) and (PCS) (r=0,58–0,75, p< 0,001) but not with the (MCS) of SF-36. Conclusion: Assessment of long term results after elbow arthroplasty yielded favourable clinical and subjective results. The clinical outcome tended to be higher than results of the patient self-rated scores. Hereby, the newly developed assessment set proved to be a feasible tool for a comprehensive assessment of elbow function. In addition to clinical outcome assessment, with this set it is possible to gain important and new insights on the relationship between objective measures and subjective patients-assessment of elbow disorders and postoperative conditions

This study assesses the clinical performance of the Souter-Strathclyde elbow arthroplasty with a standardised index and long term survivorship analysis. We undertook assessment of 68 primary Souter-Strathclyde total elbow replacements. Of 53 patients assessed with pre-operative Souter-Strathclyde charts, nine died and one was lost to follow-up, 43 had radiographic and telephone review, and 38 (88%) had clinical examination according to the Mayo Elbow Performance Index. Survival of the 43 elbows was to a mean of 72 months (range: eight to 187 months) with improvement in pain, motion, stability and function. Eight of 10 elbows in deceased patients had satisfactory scores at the last assessment. Ulnar neuropraxia occurred in eight elbows (12%), persistent sensory deficit in two (3%) and motor deficit in one. Two triceps abscesses required local skin flap cover. Revision was undertaken in 14 elbows (20%) for instability (six) bony injury (three), loosening (three) and intraoperative problems (two). The survivorship at 13 years was 74% with 62 (91%) of all elbows achieving a satisfactory Mayo score

This study assesses the clinical performance of the Souter-Strathclyde elbow arthroplasty with a standardised index and long-term survivorship analysis. We undertook assessment of 68 primary Souter-Strathclyde total elbow replacements. Of 53 patients assessed with pre-operative Souter-Strathclyde charts, nine died and one was lost to follow-up, 43 had radiographic and telephone review, and 38 (88%) had clinical examination according to the Mayo Elbow Performance Index. Survival of the 43 elbows was to a mean of 72 months (range 8 to 187). A cohort of 25 elbows available for review with > 5-year follow up had improvement in pain, motion, stability and function. Eight of ten elbows in deceased patients had satisfactory scores at the last assessment. Ulnar neuropraxia occurred in eight elbows (12%), persistent sensory deficit in two (3%) and motor deficit in one. Two triceps abscesses required local skin flap cover. Revision was undertaken in 14 elbows (20%) for instability (6) bony injury (3), loosening (3) and intraoperative problems (2). The survivorship at 13 years was 74% with 62 (91%) of all elbows achieving a satisfactory Mayo score

We have reviewed 36 of 39 consecutive patients with an average age of 68 years who had semiconstrained elbow replacement for distal humeral nonunion at an average follow-up of 50.4 months (24 to 127). Of these, 31 (86%) had satisfactory results, three (8%) had fair, and two (6%) had poor results; 32 patients (88%) had moderate or severe pain before and 91% had no or only mild discomfort after the procedure. Motion had improved from a mean arc of 29 degrees to 103 degrees before operation to 16 degrees to 127 degrees after surgery. All five flail extremities were stable at last assessment. There were seven complications (18%): two patients had deep infection, two had particulate synovitis, two had ulnar neuropathy and one had worn polyethylene bushes. Five of these seven, excluding the two with transient nueropathy, required reoperation (13%). Joint replacement arthroplasty can be a safe and reliable treatment for this difficult clinical condition, seen most commonly in elderly patients. This is a significant advance, since repeated osteosynthesis has been shown to be ineffective in most patients

Aims: To evaluate the short to medium term outcome of the Souter-Strathclyde prosthesis when used as a primary elbow arthroplasty in rheumatoid arthritis. Introduction: The Souter-Strathclyde prosthesis has been evaluated in several studies. In our hospital the operation is carried out using the same strict precautions as for lower limb arthroplasty. At the onset of surgery the ulnar nerve is handled minimally. This study looked at infection and complication rates, and also at outcome. Methods: The operations were carried out in laminar flow theatres and scrubbed staff wore exhaust suits. At the start of the procedure the ulnar nerve was decompressed, but not mobilised from its bed, and held loosely with tape while being kept moist. Cases were identified from theatre and implant records. 61 implants in 53 patients were identified. Complication and revision rates were established from case sheets. Of this group 19 patients had died, leaving 40 implants in 34 patients suitable for review. Case notes were analysed. Patients were contacted by post and were requested to fill out a DASH form. 30 patients (34 implants) responded; 2 declined to be involved leaving 31 implants in 28 patients to analyse, 78% of those available. Results: From the 61 implants there were 4 complications within the first year; one ulnar nerve palsy – transient, one dislocated prosthesis – open reduction, two wound infections. The infection rate is thus 3.3%. Overall to date 4 implants from 61 required revision, a rate of 6.6% (range 13–92 months, mean 37 months). Reasons – one loose, two periprosthetic fractures and one infection. Mean follow up at clinic was 74 months (range 36–120). Mean DASH score at follow up was 48.7 (range 4.5–81.8). Conclusion: The lower incidence of ulnar nerve palsy, compared to published studies, may be attributable to the surgical technique. The use of laminar flow theatres and exhaust suits may account for the lower infection rates. The complication rate and revision rate is favourable compared to previous studies

Aim: To evaluate the short to medium term outcome of the Souter-Strathclyde prosthesis when used as a primary elbow arthroplasty in rheumatoid arthritis. Introduction: The Souter-Strathclyde prosthesis has been evaluated in several studies. In our hospital the operation is carried out using the same strict precautions as for lower limb arthroplasty. At the onset of surgery the ulnar nerve is handled minimally. This study looked at infection and complication rates, and also at outcome. Methods: The operations were carried out in laminar flow theatres with exhaust suits. At the start of the procedure the ulnar nerve was decompressed, but not mobilised from its bed, and held loosely with tape while being kept moist. Cases were identified from theatre and implant records. 61 implants in 53 patients were identified. Complication and revision rates were established from case sheets. Of this group 19 patients had died leaving 40 implants in 34 patients suitable for review. Case notes were analysed. Patients were contacted by post and were asked to fill out a DASH form. 30 patients (34 implants) responded. 26 patients (30 implants) attended a review clinic. Results: From the 61 implants there were 4 complications (one ulnar nerve dysthesia – transient, one dislocated prosthesis – open reduction, two wound infections) within the first year. Overall, 4 implants from 62 required revision, a rate of 6.5% (range 11–92 months, mean 37 months). Reasons – One loose, two periprosthetic fractures and one infection. Mean follow up was 74 months (range 36–120). Mean DASH score at follow up was 48.7 (range 4.5–81.8). Conclusion: The low incidence of ulnar nerve palsy, compared to published studies, may be attributable to the surgical technique. The use of laminar flow theatres and exhaust suits may account for the low infection rate. The complication rate and revision rate is comparable to previous published studies