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Bone & Joint Open
Vol. 4, Issue 7 | Pages 516 - 522
10 Jul 2023
Mereddy P Nallamilli SR Gowda VP Kasha S Godey SK Nallamilli RR GPRK R Meda VGR

Aims

Musculoskeletal infection is a devastating complication in both trauma and elective orthopaedic surgeries that can result in significant morbidity. Aim of this study was to assess the effectiveness and complications of local antibiotic impregnated dissolvable synthetic calcium sulphate beads (Stimulan Rapid Cure) in the hands of different surgeons from multiple centres in surgically managed bone and joint infections.

Methods

Between January 2019 and December 2022, 106 patients with bone and joint infections were treated by five surgeons in five hospitals. Surgical debridement and calcium sulphate bead insertion was performed for local elution of antibiotics in high concentration. In all, 100 patients were available for follow-up at regular intervals. Choice of antibiotic was tailor made for each patient in consultation with microbiologist based on the organism grown on culture and the sensitivity. In majority of our cases, we used a combination of vancomycin and culture sensitive heat stable antibiotic after a thorough debridement of the site. Primary wound closure was achieved in 99 patients and a split skin graft closure was done in one patient. Mean follow-up was 20 months (12 to 30).


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_5 | Pages 10 - 10
1 May 2015
McNally M Kendal A Corrigan R Stubbs D Woodhouse A
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Background:. In 1931, Gaenslen reported treatment of haematogenous calcaneal osteomyelitis through an incision on the sole of the heel, without the use of antibiotics. We have modified his approach to allow shorter healing times and early mobilisation in a modern series of cases. Method:. Sixteen patients with Cierny-Mader Stage IIIB chronic osteomyelitis were treated with split-heel incision, calcaneal osteotomy, radical excision, local antibiotics, direct skin closure and parenteral antibiotics. 4 patients had diabetic foot infection with neuropathy, 5 had infection after open injuries, 4 had haematogenous osteomyelitis and 3 had Grade 4 pressure ulceration with bone involvement. 14 had sinuses/ulcers and 12 had undergone previous surgery. Primary outcomes were eradication of infection, time to sinus/ulcer healing, mobility and need for modified shoes. Results:. Mean hospital stay was 19.2 days (7–44). 14 patients had no recurrence of infection at final follow-up (minimum 12 months; mean 53 months). Ulcers healed between 4 and 15 weeks. 2 patients with recurrent infection required amputation. Of the 14 salvaged patients, 10 mobilised unaided. 9 required modified shoes. Conclusion:. This protocol gave effective control of infection, ulcer healing and mobilisation within an acceptable time, but amputation remains a risk


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 286 - 286
1 Sep 2012
Alani A Taylor G
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Background. A pedobarograph is a device that records pressures exerted by the foot on contact with the ground. Clinically most publications using pedobarography investigated diabetic foot pressures for prevention of ulcers, and assessing gait and sway. Only limited work was done on the effects of foot surgery on foot pressures. Any comparison between papers is hampered by the absence of available defined normal ranges of foot pressures. Aims of Study. The objective of the research project is to describe the foot pressures for 250 volunteers and to identify any trends and relationships of age, sex, body mass index (BMI), shoe & foot size and ethnic origin to foot pressures. The study is to provide a baseline upon which further comparative clinical research can be built. Materials and Methods. a sample size of 250 volunteers was determined after statistical advice. Ethics approval was sought. Recruitment was done after consent from Leicester Royal Infirmary and Leicester University. Volunteers with lower limb injury, diabetes, peripheral vascular disease or spinal cord injuries were excluded. Participants walked barefooted onto a (Takscan) matrix pressure mat. They walked at a speed they considered normal for themselves, as recommended by Taylor et al. We used the two step initiation protocol, invented by Myers-Rice et al to control the stride length, volunteers stood two steps away from the mat and hit the mat in their second step. Five steps per foot were collected for each patient and the average per foot area was calculated. The five steps method provided a coefficient of reliability of 0.94. Each foot was divided into 13 areas using the Tekscan software package. Data analysis was done using SPSS. Study participants’ characteristics (age, sex, foot size, height, weight and BMI) were summarised as a whole and by ethnic group, in tabular and graphical form. Histograms of foot pressure parameters (mean peak pressure at the medial and lateral heel, the mid foot, the head of each metatarsal and at each toe) were generated. The confidence interval was set to 95% and the level of significance to 0.05. Regression analysis testing was carried out to determine any significant relations between the variables. Coefficient of determination was reported for models including age, sex and ethnic origin, with and without adjustment for other body size measures. Results. Study population demographics, as well as BMI, height, weight and the average foot size were described. The average peak foot pressure for each foot area for each ethnic group was described and compared. Regression analysis of the variables has shown statistically significant associations between >70 years age group and low midfoot pressure, high BMI/weight and high midfoot pressure, big foot size and high midfoot pressure. The white western European group had the highest overall foot pressures


Bone & Joint Open
Vol. 1, Issue 9 | Pages 568 - 575
18 Sep 2020
Dayananda KSS Mercer ST Agarwal R Yasin T Trickett RW

Aims

COVID-19 necessitated abrupt changes in trauma service delivery. We compare the demographics and outcomes of patients treated during lockdown to a matched period from 2019. Findings have important implications for service development.

Methods

A split-site service was introduced, with a COVID-19 free site treating the majority of trauma patients. Polytrauma, spinal, and paediatric trauma patients, plus COVID-19 confirmed or suspicious cases, were managed at another site. Prospective data on all trauma patients undergoing surgery at either site between 16 March 2020 and 31 May 2020 was collated and compared with retrospective review of the same period in 2019. Patient demographics, injury, surgical details, length of stay (LOS), COVID-19 status, and outcome were compared.