Aims. Smoking is associated with post-operative complications but smokers often under-report the amount they smoke. Our objective was to determine whether a urine dipstick test could be used as a substitute for quantitative cotinine assays to determine smoking status in patients. Patients and Methods. Between September 2013 and July 2014 we conducted a prospective cohort study in which 127 consecutive patients undergoing a planned foot and ankle arthrodesis or osteotomy were included. Patients self-reported their smoking status and were classified as: ‘never smoked’ (61 patients), ‘ex-smoker’ (46 patients), or ‘current smoker’ (20 patients). Urine samples were analysed with cotinine assays and cotinine dipstick tests. Results. There was a high degree of concordance between dipstick and assay results (Kappa coefficient = 0.842, p < 0.001). Compared with the quantitative assay, the dipstick had a sensitivity of 88.9% and a specificity of 97.3%. Patients claiming to have stopped smoking just before surgery had the highest rate of disagreement between reported smoking status and urine testing. Conclusion. Urine cotinine dipstick testing is cheap, fast, reliable, and easy to use. It may be used in place of a quantitative assay as a screening tool for detecting patients who may be smoking. A positive test may be used as a trigger for further assessment and counselling. Cite this article: Bone Joint J 2016;98-B:1418–24

Introduction:. Wound healing and poor bone healing are complications seen in patients who smoke and some surgeons prefer not to operate on smokers. However, self reporting of smoking by patients may be biased. This study compares self-reporting of smoking habits and cotinine levels in the urine of our patients. Method:. 77 patients admitted for an osteotomy or arthrodesis procedure between September 2013 and May 2014 agreed to participate in this study. A questionnaire was completed and a urine sample was obtained and tested for cotinine, a metabolite of nicotine, by 2 techniques: a dipstick, the COT One Step Cotinine Test, yielding a positive result when the cotinine in the urine exceeds 200 ng/mL and the Concateno laboratory assay test, providing a mean value to give a qualitative reading whereby the cut off for non-smokers is 500ng/ml. Results:. Questionnaire results showed that 12 participants were active smokers, 35 classed themselves as ex-smokers and 30 were non-smokers. A dipstick result was negative in all the non-smokers, in 31/35 (89%) of the ex-smokers and in 4/12 (25%) of the current smokers. The dipstick test was positive in 4 self-reporting ex-smokers and only 8 of the 12 current smokers. The laboratory assay gave readings from 21 to 45,657 with higher readings being from heavier smokers. It correctly gave a value < 500 for all self-reporting non-smokers but 3 of the 35 self-reporting ex-smokers had a value between 500–5000ng/ml. Conclusion:. Whilst the majority of our patients had matching self-reporting smoking status and urine cotinine levels, 10% of self-reported ex-smokers had a high level of urine cotinine due to the test limitations or reporting bias by our patients. The £1.50 COT dipstick test is a cheap and easy way to correctly confirm a non-smoker compared to the Concateno laboratory assay which costs £7 excluding portering costs

Aims

It is well established that there is a strong association between Perthes’ disease and worsening socioeconomic deprivation. It has been suggested that the primary determinant driving this association is exposure to tobacco smoke. This study aimed to examine this hypothesis.

Objectives

To review the systemic impact of smoking on bone healing as evidenced within the orthopaedic literature.

Aims

Prosthetic joint infection (PJI) remains a serious complication that is associated with high morbidity and costs. The aim of this study was to prepare a systematic review to examine patient-related and perioperative risk factors that can be modified in an attempt to reduce the rate of PJI.