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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 51 - 51
1 Mar 2012
Hay D Izatt M Adam C Labrom R Askin G
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Introduction. Luk (Luk et al. Spine vol 23(21) 2303-2307 1998) has shown that in posterior surgery, the correction achieved can be predicted by fulcrum bending films. The relevance to anterior correction has been disputed, as this commonly involves shortening the spine by the removal of intervertebral discs. The aim of the study was to see whether the pre-operative bending angle reflected the degree of correction achieved. Method. 91 patients with a structural thoracic curve had an anterior endoscopic correction using a single rod. The mean age was 16.1 years. (range 10-46) The majority of curves were Lenke type 1 (79%) or Type 2 (8%). In all cases disc clearance and bone grafting were performed. All had pre-operative fulcrum bending films. The mean Cobb angle achieved at the pre-operative bending film was compared with the post-operative correction at 2 months. The FBCI (Fulcrum Bending Correction Index) and correction rates were also calculated. The FBCI is calculated by dividing the correction rate by the fulcrum flexibility and expressed as a percentage. It takes into account the pre-operative flexibility of the curve. Results. The mean Cobb angle achieved at the pre-operative bending film was 20.4 degrees. The mean Cobb angle of the corrected curve at 2 months following surgery was 20.4 degrees, (p=0.96). The mean FBCI was 107%. The overall correction rate was 60.1%. Conclusion. In our series fulcrum bending films have been highly predictive of the correction achieved following anterior endoscopic correction. The correction rate of 60.1% is in keeping with other series. In addition, the FBCI was 107%. The instrumentation had corrected to the flexibility achieved at the time of the pre-operative bending films. This implies that the discectomies performed at time of surgery had not significantly increased the correction achieved


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_4 | Pages 60 - 60
1 Feb 2017
Khan H Meswania J Riva F Pressacco M Panagiotidou A Coathup M Blunn G
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Background

Hip resurfacing has advantages for the young active patient with arthritis; maintaining a large range of motion, preserving bone stock, and reduced dislocation risk. However high serum metal ion levels with metal-on-metal resurfacing, and their clinical implications, has led to a decline in the use of hip resurfacing. Ceramic bearing surfaces display the lowest frictional torque and excellent wear rates. Recent developments have enabled large, strong ceramic materials to be used as resurfacing components. Any wear debris that is generated from these articulations is inert. However an all-ceramic hip resurfacing could be at risk of fracture at the head-stem junction. A new ceramic hip resurfacing system with a titanium-ceramic modular taper junction has been developed. The introduction of a taper introduces the potential for fretting corrosion; we sought to determine the extent of this in an in-vitro model, and compared this prosthesis to the conventional 12/14 titanium-cobalt chrome (Ti6Al4V-CoCr) taper junction.

Methods

To simulate the gait cycle, sinusoidal cyclical loads between 300N-2300N, at a frequency of 3Hz, were applied to different head-neck offsets generating different bending moments and torques. The effect of increasing the bending moment and frictional torque were tested separately. Furthermore, the resurfacing head was mounted in a fixture held with just the stem, thus representing complete bone resorption under the head. An electrochemical assessment using potentiostatic tests at an applied potential of 200mV, was used to measure the fretting current (μA) and current amplitude (μA). In a short-term 1000 cycle test, six neck lengths (short to xxx-long) of the Ti6Al4V-CoCr taper were compared to the standard neutral (concentric), and 3mm A/P offset stem options for the resurfacing design. To represent frictional torque, four increments of increasing torque (2-4-6-8Nm) were applied to both tapers. In a long term test with the resurfacing stem, the worst-case scenario of the eccentric offset option and 8Nm of torque were applied, and potentiostatic measurements were taken every million cycles, up to 10 million cycles.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 192 - 192
1 Mar 2013
Harato K Tanikawa H Okubo M
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Introduction

According to previous reports, unilateral total knee arthroplasty (TKA) would produce the asymmetric changes of lower extremity in the coronal plane in patients with bilateral knee osteoarthritis (OA). To our knowledge, little attention has been paid to the alignment changes of trunk and contralateral limb. It was hypothesized that the unilateral correction of knee deformity would affect trunk bending in the coronal plane after unilateral total knee arthroplasty. The purpose of the current study was to investigate trunk bending in the coronal plane before and after the surgery.

Methods

Twenty patients (17 Females and 3 Males; mean 76 years old) with bilateral symptomatic knee osteoarthritis participated. They had radiographic bilateral OA of at least grade 3 severities according to the Kellgren-Lawrence scale. All the subjects underwent unilateral TKA using Balanced Knee System®, posterior stabilized design (Ortho Development, Draper, UT). All the subjects provided informed consent. All methods and procedures were approved by our institution's ethics committee. They were asked to step on the two scales and perform relaxed standing for five seconds, placing each foot on each scale independentlys. Thereafter, anteroposterior radiographs of the whole spine and bilateral long legs were taken with use of a vertical 35.4 × 101.7-cm film.

The shoulder tilting angle was defined by the height difference between the centers of the right and left acromioclavicular joints, and the pelvic tilting angle was defined by the height difference between the centers of the right and left femoral heads. To evaluate trunk bending, the shoulder-pelvis bending angle was defined as the angle between the shoulder girdle line (Fig. 1, Line a) and the pelvic line (Fig. 1, Line b). Femorotibial angle (FTA) was also evaluated. These radiographs were taken before the surgery and on postoperative day 21.

Simultaneously, knee flexion angles on TKA side, subjective pain level on TKA side and vertical knee forces (% body weight; BW) on TKA side during relaxed standing were also examined. Data evaluations were done both before and on postoperative day 21. Statistical difference between the data was evaluated using two-tailed Wilcoxon t-test. P-values of < 0.05 were considered as significant.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 316 - 316
1 Mar 2013
Russell N Rives A Bruce W Pelletier M Walsh W
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Introduction

Gamma Irradiation is often considered the gold standard for sterilizing bone allograft. However, a dose dependant decrease in the static mechanical properties of gamma irradiated bone has been well established. Supercritical Fluid Sterilization (SCF) using carbon dioxide represents a potential alternate method to sterilize allografts. This study aimed to evaluate the effect of SCF on the static and dynamic (fatigue) properties of cortical bone in 3-point bending.

Methods

Eighty paired 18-month old rabbit humeri were randomized to 4 treatments: Gamma Irradiation at 10 kGy or 25 kGy, SCF Control and SCF with Peracetic Acid (Figure 1) (n=20 pairs per group). One side was treated while the other acted as a control. Ten pairs in each group were tested statically at 5 mm/min; while ten were tested dynamically between 15–150 N at 4 Hz. Samples were fatigued to failure or 50000 cycles (run-out). All testing was performed at room temperature in a saline bath. A 2-tailed t-test was used to test for significance within pairs and a one-way ANOVA with Games-Howell post-hoc test was used to test between groups.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 79 - 79
1 Jan 2016
Cho S Youm Y Kim J
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Purpose

The NexGen® legacy posterior stabilized (LPS)-Flex total knee system (Zimmer, Warsaw, IN) is designed to provide 150° of flexion following total knee arthroplasty (TKA). But, recent reports found a high incidence of loosening of the femoral component related to the deep flexion provided. We evaluated 9- to 12-year clinical and radiological follow-up results after NexGen® LPS-Flex TKA.

Materials and Methods

A retrospective evaluation was undertaken of 209 knees in 160 patients (21 males, 139 females) who were followed up for more than 9 years after Nexgen®LPS-Flex TKA. Evaluations included preoperative and postoperative range of motion(ROM), Knee Society(KS) knee score, function scores, tibiofemoral angle and assessment of postoperative complications.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_11 | Pages 32 - 32
1 Nov 2022
Bernard J Bishop T Herzog J Haleem S Ajayi B Lui D
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Abstract. Aims. Vertebral body tethering (VBT) is a non-fusion technique to correct scoliosis allowing correction of scoliosis through growth modulation (GM) by tethering the convex side to allow concave unrestricted growth similar to the hemiepiphysiodesis concept. The other modality is anterior scoliosis correction (ASC) where the tether is able to perform most of the correction immediately where limited growth is expected. Methods. A retrospective analysis of 20 patients (M:F=19:1 – 9–17 years) between January 2014 to December 2016 with a mean five-year follow-up (4 to 7). Results. There were ten patients in each group with a total of 23 curves operated upon. VBT-GM mean age −12.5 years (9 to 14), mean Risser of 0.63 (0 to 2) and VBT-ASC was 14.9 years (13 to 17) and mean Risser of 3.66 (3 to 5). Mean preoperative VBT-GM Cobb was 47.4° (40°–58°) compared to VBT-ASC 56.5° (40°–79°). Postoperative VBT-GM Cobb was 20.3° and VBT-ASC was 11.2°. The early postoperative correction rate was 54.3% versus 81% whereas Fulcrum Bending Correction Index (FBCI) was 93.1% vs 146.6%. Latest Cobb angle at mean five years' follow-up was 19.4° (VBT-GM) and 16.5° (VBT-ASC). Overall, 5% of patients required fusion. Conclusion. We show a high success rate (95%) in helping children avoid fusion at five years post-surgery. VBT is a safe technique for scoliosis correction in the skeletally immature patient. This is the first report at five years showing two possible options of VBT depending on the skeletal maturity of the patient: GM and ASC


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 93 - 93
1 Jan 2016
Parekh J Gold J Noble P
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Introduction. Manifestation of high interface stresses coupled with micromotion at the interface can render the taper lock joint in a modular hip replacement prosthesis at risk for failure. Bending can lead to crevice formation between the trunnion and the head and can potentially expose the interface to the biological fluids, generating interface corrosion. Additionally, development of high stresses can cause the material to yield, ultimately leading to irreversible damage to the implant. The objective of this study is to elucidate the mechanical response of taper junction in different material combination assemblies, under the maximum loads applied during everyday activities. Methods. Computer simulations were executed using a verified FE model. A stable hexahedral mesh (33648 elements) was generated for the trunnion (taper size: 12/14mm) and a tetrahedral mesh (51182 elements) for the head (CoCr, size: 32mm). An assembly load of 4000N was applied along the trunnion axis followed by the application of a load of 230–4300N at 25° and 10° angle to the trunnion axis in the frontal and sagittal planes. A linear static solution was set up using Siemens NX Nastran. Two material combinations were tested - cobalt-chrome head with a titanium alloy trunnion and cobalt chrome head with a cobalt-chrome trunnion. Results. Table1 compares the results obtained from the simulation to those observed in experimental simulations performed under similar loading conditions in our lab. Larger vertical interface displacement was observed in the CoCr-CoCr assembly during toggle-inducing loads. The trunnion bending inside the femoral head was higher in the Ti-CoCr assembly (0.056) compared to the CoCr-CoCr assembly (0.027) with the overall bending of the Ti-CoCr assembly also observed to be much higher (Fig.1). Negligible difference between the stress measured in the femoral head and taper was observed (Fig.2). Discussion. Bending could potentially lead to the development of higher stresses especially under multiple cycles of loading. Fatigue and plastic deformation could result in irreparable damage to the interface leading to implant failure. Additionally, bending causes a separation of the interfaces at the trunnion-head junction, leading to crevice formation, triggering corrosion by exposure to the surrounding physiological environment. Thus, it is crucial that we understand the mechanics of the trunnion-head junction especially under conditions of functional loading


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_6 | Pages 55 - 55
1 Jul 2020
Jalal MMK Wallace R Simpson H
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Many pre-clinical models of atrophic non-union do not reflect the clinical scenario, some create a critical size defect, or involve cauterization of the tissue which is uncommonly seen in patients. Atrophic non-union is usually developed following high energy trauma leading to periosteal stripping. The most recent reliable model with these aspects involves creating a non-critical gap of 1mm with periosteal and endosteal stripping. However, this method uses an external fixator for fracture fixation, whereas intramedullary nailing is the standard fixation device for long bone fractures. OBJECTIVES. To establish a clinically relevant model of atrophic non-union using intramedullary nail and (1) ex vivo and in vivo validation and characterization of this model, (2) establishing a standardized method for leg positioning for a reliable x-ray imaging. Ex vivo evaluation: 40 rat's cadavers (adult male 5–6 months old), were divided into five groups (n=8 in each): the first group was fixed with 20G intramedullary nail, the second group with 18G nail, the third group with 4-hole plate, the fourth group with 6-hole plate, and the fifth group with an external fixator. Tibiae were harvested by leg disarticulation from the knee and ankle joints. Each group was then subdivided into two subgroups for mechanical testing: one for axial loading (n=4) and one for 4-point bending (n=4) using Zwick/Roell® machine. Statistical analysis was carried out by ANOVA with a fisher post-hoc comparison between groups. A p-value less than 0.05 was considered statistically significant. To maintain the non-critical gap, a spacer was inserted in the gap, the design was refined to minimize the effect on the healing surface area. In vivo evaluation was done to validate and characterize the model. Here, a 1 mm gap was created with periosteal and endosteal stripping to induce non-union. The fracture was then fixed by a hypodermic needle. A proper x-ray technique must show fibula in both views. Therefore, a leg holder was used to hold the knee and ankle joints in 90º flexion and the foot was placed in a perpendicular direction with the x-ray film. Lateral view was taken with the foot parallel to the x-ray film. Ex vivo: axial load stiffness data revealed that intramedullary nails are significantly stronger and stiffer than other devices. Bending load to failure showed that 18G nails are significantly stronger than 20G, thus it is used for the in vivo experiments. In vivo: final iteration revealed 3/3 non-union, and in controls with the periosteum and endosteum intact but with the 1mm non-critical gap, it progressed to 3/3 union. X-ray positioning: A-P view in supine position, there was an unavoidable degree of external rotation in the lower limb, thus the lower part of the fibula appeared behind the tibia. To overcome this, a P-A view of the leg was performed with the body in prone rather, this arrangement allowed both upper and lower parts of the fibula to appear clearly in both views. We report a novel model of atrophic non-union, the surgical procedure is relatively simple and the model is reproducible


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_4 | Pages 61 - 61
1 Feb 2017
Khan H Riva F Pressacco M Meswania J Panagiotidou A Coathup M Blunn G
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Background. Complications of metal-on-metal hip resurfacing, leading to implant failure, include femoral notching, neck fracture, and avascular necrosis. Revision arthroplasty options include femoral-only revision with a head, however mis-matching radial clearance could accelerate metal ion release. Alternatively, revision of a well-fixed acetabular component could lead to further bone loss, complicating revision surgery. We have developed a ceramic hip resurfacing system with a titanium-ceramic taper junction; taking advantage of the low frictional torque and wear rates that ceramic affords. Taking a revision scenario into account, the ceramic head has a deep female taper for the resurfacing stem, but also a superficial tapered rim. Should revision to this resurfacing be required, any femoral stem with a 12/14 taper can be implanted, onto which a dual taper adaptor is attached. The outer diameter of the taper adaptor then becomes the male taper for the superficial taper of the ceramic head; ultimately allowing retention of the acetabular component. In an in-vitro model, we have compared the fretting corrosion of this taper adaptor to existing revision taper options: a titanium-cobalt chrome (Ti-CoCr) taper junction, and a titanium-titanium sleeve-ceramic (Ti-Ti-Cer) taper junction. Methods. To simulate gait, sinusoidal cyclical loads between 300N-2300N, at a frequency of 3Hz was applied to different neck offsets generating different bending moments and torques. Bending moment and frictional torque were tested separately. An electrochemical assessment using potentiostatic tests at an applied potential of 200mV, was used to measure the fretting current (μA) and current amplitude (μA). In a short term 1000 cycle test with bending moment, four neck lengths (short to x-long) were applied. For frictional torque, four increments of increasing torque (2-4-6-8Nm) were applied. In a long-term test using the taper adaptor, the combination of worst-case scenario of bending and torque were applied, and fretting currents measured every million cycles, up to 10 million cycles. Results. Short-term test: When adjusting bending moment the taper adaptor displayed equivalent fretting currents for the short and medium neck lengths. Using the long neck the taper adaptor displayed a higher fretting current, though this was not significant (Kruskal-Wallis test). However, using the X-Long adaptor the fretting current was significantly higher than the other tapers (Fig. 1). Across the range of frictional torques, the taper adaptor displayed equivalent fretting currents to the Ti-CoCr single taper. The Ti-Ti-Cer displayed the lowest fretting currents but this was not significant when compared to the other combinations (Fig. 2). Long-term test: combining the worst case bending (X-Long) and torque (8Nm) showed consistent fretting currents and current amplitudes across 10 million cycles, with no significant variance of the median values (Fig. 3). Conclusion. Electro-chemical testing has highlighted caution if revision arthroplasty is performed using the X-Long taper adaptor. However for shorter neck lengths, fretting corrosion is comparable to existing revision tapers. The LIMA ceramic resurfacing arthroplasty is an integrated system and can be safely revised to a conventional hip system using a dual taper head, and taper adaptor


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 56 - 56
1 Jan 2016
Moussa H Scemama C Kerboull L
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Introduction. Excellent long-term survival rates associated with the absence of stem subsidence have been achieved with total hip arthroplasty (THA) using femoral components cemented line-to-line (“French Paradox”). Recently, short stems have been introduced in order to preserve diaphyseal bone and to accommodate to minimal invasive THA and a variety of clinical situations. The aim of the current study was to quantify the rotational and tilting stability of a Kerboull stem of varying length after line-to-line cementation using a validated in-vitro model. Materials & methods. The femoral component made of M30NW stainless steel was derived from the original Kerboull stem. It had a double taper, a highly polished surface, and a quadrangular cross-section. Four stem lengths were designed from the original length with a distal reduction of 6, 12, 17 and 22%, whereas the proximal body geometry of the implant remained unaffected. For each stem length, five specimens were implanted into a non-canal synthetic femoral model. The femoral preparation was performed in order to obtain rotational and tilting stability of the stem prior to the line-to-line cementation. Spatial micro-motions of the specimens were investigated using a validated rotational measuring set-up. In addition, in a second separate step, the specimens were exposed to a ventro-dorsal moment to mimic varus-valgus moment. Statistical analysis was performed using ANOVA with Fisher PLSD. Results. The maximum torque transfer from the stem within the cement mantle to the composite femur occurred at the level of the lesser trochanter, whereas the lowest torque transfer was observed at the tip of the stem. The relative movement at the tip was significantly greater for the original length when compared to 6 and 12% length reduction (p = 0.036 and 0.033, respectively). The 12% reduction resulted in a significant lower mean overall movement when compared to the original length (p = 0.044). The tilting behavior according to the stem lengths indicated that proximal bending value was significantly increased for 17% reduction when compared to 6% and 12% reduction (p = 0.035 and 0.032, respectively). Bending of the tip of the stem was in the same direction as the shoulder, indicating a backlash from the tip. At the tip, relative bending was increased when compared to the previous length up to 12% reduction and then decreased. However, the difference was not significant (p <0.05). Discussion & conclusion. The stem lengths evaluated in the current study showed similar results to previously reported cemented stems of different designs, indicating a close fixation to composite bone with small relative movement. Both 6 and 12% shortened versions showed significant reduced relative movement at the tip when compared to the original length, suggesting a limited role for the tip in terms of rotational stability. Regarding the medio-lateral torque, the stems always reacted with a backlash and did not tilt like a rigid body. Although not significant, the distal bending tended to increase with reduced length. These findings led us to develop a Kerboull stem with 12% distal reduction that is currently under clinical trial


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 180 - 180
1 Mar 2013
Gasparini G Guzzi P Pugliese T Galasso O
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The removal of cement debris at the time of primary and revision joint replacement has been facilitated through the introduction of coloured bone cements. Up to date, few studies have evaluated the effect of methilene blue dye on physical, mechanical and pharmacological properties of cements. In this light, we evaluated the effects of adding methylene blue to bone cement with or without antibiotics (gentamicin, vancomycin or both). The addition of methylene blue to plain cement significantly decreased its mean compression (95.4±3 MPa vs 100.1±6 MPa, p = 0.03) and bending (65.2±5 MPa vs 76.6±4 MPa, p < 0.001) strengths, mean setting time (570±4 seconds vs 775±11 seconds, p = 0.01), as well as its mean elastic modulus (2744±97 MPa vs 3281±110 MPa, p < 0.001). Bending resistance decreases after the supplementation of the coloured cement with vancomycin and gentamicin (55.7±4 MPa vs 65.2±5 MPa, p < 0.001). The release of antibiotics from the bone cement was significantly decreased by the methylene blue. Indeed, the release of gentamicin alone was 385.5±26 μg in comparison to 228.2±24 μg when the methylene blue was added (p < 0.001), while the release of gentamicin in combination with vancomycin was 613±25 μg vs 498.5±70 μg (p = 0.018) when the dye was added to the same formulation. With this study we demonstrated several theoretical disadvantages of the antibiotic-loaded bone cement coloured with methylene blue, although caution should be exercised in transferring our findings to the clinical context. Based on our findings, we do not recommend methylene blue supplementation of PMMA for routine clinical use


Bone & Joint Open
Vol. 1, Issue 4 | Pages 47 - 54
2 Apr 2020
Al-Mohrej OA Elshaer AK Al-Dakhil SS Sayed AI Aljohar S AlFattani AA Alhussainan TS

Introduction

Studies have addressed the issue of increasing prevalence of work-related musculoskeletal (MSK) pain among different occupations. However, contributing factors to MSK pain have not been fully investigated among orthopaedic surgeons. Thus, this study aimed to approximate the prevalence and predictors of MSK pain among Saudi orthopaedic surgeons working in Riyadh, Saudi Arabia.

Methods

A cross-sectional study using an electronic survey was conducted in Riyadh. The questionnaire was distributed through email among orthopaedic surgeons in Riyadh hospitals. Standardized Nordic questionnaires for the analysis of musculoskeletal symptoms were used. Descriptive measures for categorical and numerical variables were presented. Student’s t-test and Pearson’s χ2 test were used. The level of statistical significance was set at p ≤ 0.05.