Introduction

Collapse of femoral head associated with end-stage arthritis form hallmark of osteonecrosis of femoral head. Purpose was to assess efficacy of platelet rich plasma following core decompression in early stage of osteonecrosis of femoral head.

Introduction

Patients with osteonecrosis of the femoral head are typically younger, more active, and often require high rates of revision following primary total hip arthroplasty. However, outcomes of revision hip arthroplasty in this patient population have been rarely reported in the literature. The purpose of this study was to report the intermediate-term clinical and radiographic outcomes of revision hip arthroplasty in patients with osteonecrosis of the femoral head.

Introduction

The natural history of osteonecrosis of the femoral head (ONFH) is not cleanly understood, but most of them progresse to the joint destruction and requires total hip replacement arthroplasty. There are several head preserving procedure, but no single therapeutic method proved to be effective in preventing progression of the disease. The possibility has been raised that implantation of bone marrow containing osteogenic precursors may be effective in the treatment of this disease. However, there are no long-term follow-up results of cell therapy for ONFH. AS far as we know, there are no reports about bone graft and cell therapy for ONFH. Therefore, we performed a prospective clinical and radiological evaluation on ONFH treated with core decompression combined with autoiliac bone graft and an implantation of autologous bone marrow cells as a therapeutic method of ONFH.

Introduction

The pathophysiology of osteonecrosis of femoral head (ONFH) is uncertain for most cases with speculation of vascular impairment and changes in cell biology due to multi-factorial etiologies including corticosteroid, alcohol, smoking, trauma, radiation or caisson disease and genetic. Extracorporeal shockwave therapy (ESWT) began with an incidental observation of osteoblastic response pattern during animal studies in the mid-1980 that generated an interest in the application of ESWT to musculoskeletal disorders. The mechanism of shockwave therapy is not fully understood but several reports showed better clinical outcomes and promoted bone remodelling and regeneration effect of the femoral head after ESWT in ONFH. Therefore, we compared the clinical results of the use of extracorporeal shock wave therapy (ESWT) on the patients with ONFH in radiographic staging.

Post-traumatic osteonecrosis of the femoral head (ONFH) is a major complication of femoral neck fractures that require numerous solutions. The purpose of the current study is to investigate the effects of platelet-rich plasma (PRP) incorporated autologous granular bones graft for the treatment of pre-collapse stages (ARCO stage II-III) of post-traumatic ONFH.

A total of 46 patients were eligible and enrolled into the study. 24 patients were treated with core decompression and PRP incorporated autologous granular bones graft (treatment group: 9 females and 15 males, age range, 16–39 years), and 22 patients with core decompression and autologous granular bones graft (control group: 6 females and 16 males, age range, 18–42 years. During a minimum duration of follow-up of 36 months, multiple imaging techniques including X-ray and computed tomography (CT) scanning were used to evaluate the radiological results, and Harris hip score (HHS) and the visual analogue scale (VAS) were chosen to assess the clinical results.

Both treatment group and control group had a significant improved HHS (P < 0.001). The minimum clinically important difference (MCID) for HHS was reached in 91.7% of treatment group and 68.2% of control group (P = 0.0449). HHS in treatment group was significantly higher than control group at the last follow-up (P = 0.0254). VAS score was significantly declined in treatment group when compared with control group (P = 0.0125). Successful clinical results were achieved in 21 of 24 patients (87.5%) in treatment group compared with 13 of 22 patients (59.1%) in control group (P = 0.0284). Successful radiological results were achieved in 19 of 24 patients (79.2%) in treatment group compared with 11 of 22 patients (50%) in control group (P = 0.0380). The survival rates using requirement for further hip surgery as an endpoint were higher in treatment group in comparison to control group (P = 0.0260).

The PRP incorporated autologous granular bones graft is a safe and effective procedure for the treatment of pre-collapse stages (ARCO stage II-III) of post-traumatic ONFH.

Objectives

The purpose of the present study was to describe the long-term results of THA for ONFH in patients with SLE.

Background

Core decompression (CD) is effective to relieve pain and delay the advent of total hip arthroplasty (THA) for osteonecrosis of the femoral head (ONFH). However, the influence of CD on the subsequent THA has not been determined yet.

[Background]

Bipolar hemiarthroplasty (following BHA) have historically had poor results in patients with idiopathic osteonecrosis of femoral head (OFNH). However, most recent report have shown excellent results with new generation BHA designs that incorporate advances in bearing technology. These optimal outcomes with bipolar hemiarthroplasty will be more attractive procedure for young patients who need bone stock for future total arthroplasty. The purpose of the current study was to evaluate the clinical and radiographic finding of this procedure for the treatment of OFNH at our institution after 7-to 21years follow-up.

Purpose

Proximal femoral osteotomy is an attractive joint preservation procedure for osteonecrosis of the femoral head. The purpose of this study was to investigate the cause of failure of proximal femoral osteotomy in patients with osteonecrosis of the femoral head.

Background

The short stem prosthesis showed good results in patients with primary osteoarthritis. However, there were a few studies about the short stem THA in patients with osteonecrosis of the femoral head (ONFH).

BACKGROUND CONTEXT. Ceramic bearings are widely used in total hip arthroplasty (THR) along with metal and polyethylene bearings. There were several studies in past few years evaluating the advantage of one over the other. The young population with high activity levels has an increased risk of wear debris production at bearing surface and subsequent implant failure. Recently, interest and use of a ceramics with high wear resistance has been growing. Early reports on ceramic on ceramic THR have demonstrated excellent clinical and radiological results. PURPOSE. To evaluate clinical, functional and radiological outcomes of cement-less ceramic on ceramic primary total Hip Replacement (THR) in young patients (<50 years age) with diagnosis of avascular necrosis femoral head. STUDY DESIGN. Single - centre, prospective comparative study of prospectively collected outcomes, with a minimum of 12 month follow-up. PATIENT SAMPLE. 30 patients who underwent cement-less ceramic on ceramic primary THR in young patients (< 50 years age) for avascular necrosis of femoral head. OUTCOME MEASURES. For clinical evaluation, Harris hip scores was measured pre-operatively and post-operatively at predefined intervals. For radiological evaluation, Post- operative radiographs were checked for alignment of femoral stem, loosening of stem, presence of heterotopic ossification, loosening of acetabular component at predefined regular intervals. METHOD. This study included 30 patients, who underwent cement-less ceramic on ceramic primary THR in young patients (< 50 years age) for avascular necrosis of femoral head between July 2013 to April 2015 with a minimum of 12 month follow –up. RESULTS. The mean Harris hip score in our study increased from 32.73 pre-operatively to 87.8 post-operatively at the latest follow up with 90% hips having good to excellent results. This improvement was statistically significant (p<0.005). On evaluation of alignment of femoral stem 27 stems were central (90%) and 3 stems found to be in valgus (10%) and none to be in varus position. There was no significant correlation between stem alignment and clinical outcome based on Harris hip score. Not a single case of focal osteolysis, stem loosening or heterotopic ossification was seen in our study till latest follow-up. None of the major complication was noticed during evaluation of our cases except minor chronic hip pain in one patient which did not restricted his daily living activities. CONCLUSION. In our study, we found better results of ceramic on ceramic THR for younger patients(<50 years age) comparable to previous studies with no serious complication found in any patient. Based on our study, we recommend ceramic on ceramic THR for younger patients in the age group of less than 50 years of age. We need a study of large sample size with long term follow up to further confirm the findings of our study

Since its creation, labral repair has become the preferred method among surgeons for the arthroscopic treatment of acetabular labral tears resulting in pain and dysfunction for patients. Labral reconstruction is performed mainly in revision hip arthroscopy but can be used in the primary setting when the labrum cannot be repaired or is calcified. The purpose of this study was to compare the survival between primary labral repair and labral reconstruction with survival defined as no further surgery (revision or total hip replacement). Patients who underwent labral repair or reconstruction between January 2005 and December 2018 in the primary setting were included in the study. Patients were included if they had primary hip arthroscopy with the senior author for femoroacetabular impingement (FAI), involving either labral reconstruction or labral repair, and were within the ages of 18 and 65 at the time of surgery. Exclusion criteria included confounding injuries (Leggs Calves Perthes, avascular necrosis, femoral head fracture, etc.), history of unilateral or bilateral hip surgeries, or Tönnis grades of 2 or 3 at the time of surgery. Labral repairs were performed when adequate tissue was available for repair and labral reconstruction was performed when tissue was absent, ossified or torn beyond repair. A total of 501 labral repairs and 114 labral reconstructions performed in the primary setting were included in the study. Labral reconstruction patients were older (37±10) compared to labral repair (34±11).(p=0.021). Second surgeries were required in 19/114 (17%) of labral reconstruction and 40/501(8%) [odds ratio: 2.3; 95% CI 1.3 to 4.2] (p=0.008). Revision hip arthroscopy were required in 6/114(5%) labral reconstructions and 33/501(6.5%) labral repair (p=0.496). Total hip replacement was required in 13/114 labral reconstructions and 7/501 labral repairs [odds ratio:9.1 95%CI 3.5 to 23] (p=< 0.01). The mean survival for the labral repair group was 10.2 years (95%CI:10 to 10.5) and 11.9 years (98%CI:10.9 to 12.8) in the labral reconstruction group. Conversion to total hip was required more often following primary labral reconstruction. Revision hip arthroscopy rates were similar between groups as was the mean survival, with both over 10 years. Similar survival was seen in labral repair and reconstruction when strict patient selection criteria are followed

Femoral trans-trochanteric rotational osteotomy(TRO) is widely used for the younger patients who have idiopathic osteonecrosis of femoral head. However, it usually converts to THA, and in hip arthroplasty, the procedure is commonly technically demanding and surgeon needs higher level of surgical technique. This study was designed to investigate comparison between simple THA and THA following TRO, and indicates specific surgical techniques of THA following TRO. Materials and Methods. Between 2002 and 2012, the senior authors performed 20 cementless THA in 16 patients who had followed after TRO. The operation time, blood loss, post-operative X-ray findings, and overall clinical results (JOA score) were investigated. These data were compared with simple THA following 10 years. Results. A mean duration between TRO and THA was 58 month, a mean age at the time of THA was 52.1 years old. Pre-operative classification was all Type C and stage 2 or higher stage. Osteonecrosis of femoral head before THA was mean 56.2%. Operation time was 160 minutes, and mean blood loss was 764 g. In post-operative X-ray findings, a cup was at original anatomy in place in all cases. There is a tendency of slight varus femoral stem position after THA following TRO. The JOA score was improved from 42.1 to 74.2. Discussion. Technically, there are a couple of issues in THA following TRO. Specific surgical techniques are needed. Surgical results depend on hip range of motion before THA. There is a difficulty of improvements in ROM after THA following TRO

Osteonecrosis of femoral head is well known and recognised complication in Sickle cell disease patients. Due to the severity of the Osteonecrosis, hip pain is major limiting factor for these patients requiring total hip arthroplasty in relatively young age. We studied and report our results in total hip arthroplasty of sickle cell patients. We studied 80 patients from our combined Orthopaedic & Haematology Sickle cell clinic. Twenty four patients had painful Osteonecrosis with secondary osteoarthritis of hip and underwent total hip arthroplasty. Three patients had bilateral hip replacements. A total of twenty seven replacements were studied retrospectively. 19 patients had uncemented (Corail/Pinnacle), 5 patients had hybrid(Pinnacle/Exeter) and 3 patients had cemented(Exeter) total hip arthroplasties respectively. The patients were serially followed up for clinical and radiological assessments for loosening. Oxford hip score (OHS) was used to assess the functional outcome. The average age of the patients at the time of surgery was 38.4 (Range – 20 to 59 years. The average follow up was 5.1 years (Range – 6 months to 10 years). There were 13 female and 11 male patients. The average oxford hip score was 38.07 with 10% infection rate and 11% aseptic loosening. Arthroplasties carry high risk in patients with sickle cell disease. We report lower rates of infection and loosening rates compared to the earlier studies. Combined Haematological and Orthopaedic team input is optimal during assessment, surgery, peri-operative period and follow up. Our results of total hip replacements in sickle cell disease patients are good

Periprosthetic femoral fractures are becoming increasingly common and are a major complication of total hip arthroplasty (THA) and bipolar hemiarthroplasty (BHA). We report a retrospective review of the outcomes of treatment of 11 periprosthetic fractures after femoral revision using a long stem. Eleven female patients with a mean age of 79.2 years (70 to 91 years) were treated for a Vancouver type B1 fracture between 1998 and 2013. The status of the initial arthroplasty was THA in 5 patients and BHA in 6 patients. The original diagnosis was femoral neck fracture in 5 patients, osteoarthritis in 5 patients, and avascular necrosis of femoral head in 1 patient. Seven patients had had a cemented femoral component and 4 had had a cementless femoral component. The mean numbers of previous surgeries were 3.2 times (2 to 5 times). A previous history of fracture in the same femur was found in 7 hips including 5 femoral neck fractures, 3 periprosthetic fractures. The cause of the latest revision surgery was aseptic loosening in 6 hips, periprosthetic fracture in 3 hips, and infection in 2 hips. The average time to fracture after femoral revision using a long stem was 106.5 months (12 to 240 months). The average follow-up was 58.9 months (8 to 180 months). The fracture pattern was a transverse fracture in 6 hips and an oblique fracture in 5 hips. The type B1 fractures were treated with open reduction and internal fixation in 9 hips, 6 of which were reinforced with bone grafts. Seven patients were treated with a locking compression plate and cerclage wiring, and 2 patients were treated with a Dall-Miles system. Two other periprosthetic fractures were treated with femoral revision. One was revised because of stem breakage, and the other was a transverse fracture associated with very poor bone quality, which received a femoral revision with a long stem and a locking compression plate. All fractures except one achieved primary union. This failed case had a bone defect at the fracture site, and revision surgery using a cementless long stem and allografts was successful. These finding suggest that a type B1 fracture after revision using a long stem associated with very poor bone quality or bone loss might be considered as a type B3 fracture, and femoral revision might be the treatment of choice

Post-traumatic avascular necrosis of the femoral head usually occurs after hip dislocation and femoral neck fracture. Recently along the development of hip arthroscopy, early stage of avascular necrosis of the femoral head can be treated rthroscopically. We hereby present two cases of post-traumatic avascular necrosis patients treated with hip arthroscopy. Case 1. Twenty one year old female patient came to the hospital because of fall from height of 3 floors. Left acetabular fracture, both superior pubic rami fractures and severely displaced left femoral neck fracture were identified at the emergency department (Fig. 1-A). She underwent surgery at the injury day. After the repair of ruptured urinary bladder, internal fixation of the femoral neck was done. Four cannulated screws with washers were inserted for displaced femoral neck fracture, consistent with garden stage IV (Fig. 1-B). Skeletal traction of ipsilateral lower extremity was applied four weeks after the surgery for acetabular fracture. She visited us for painful limitation of motion on left hip at eight months postoperatively. Plain radiograph showed collapse of femoral head and osteophyte formation which were caused by post-traumatic avascular necrosis (Fig. 1-C,D). Femoral head was perforated by a screw. She was planned to remove the screw and resect the osteophyte arthroscopically. On arthroscopic examination, severe synovitis and folded, collapsed femoral cartilage were identified (Fig. 1-E). Screws were removed and osteophyte were also resected (Fig. 1-F). We filled the cavity caused by the screws with allogenic strut graft for structural support. After the surgery, pain was relieved and she came back to her active daily living and for six months, no other complication nor further collapse were identified postoperatively. Case 2. Fourty year old male patient was admitted to the hospital for fall from height about fifteen feet from the ground. Left femoral neck fracture was identified on the emergency department. Previously he had underwent intramedullary nailing for the femoral shaft fracture about five years ago. Urgent internal fixation with four cannulated screws was done on the day of injury. The fixation was unsatisfactory because previously inserted intramedullary nail hindered the proper trajectory of screws. Furthermore, direction of cephalad interlocking holes of the nail were not consistent with the anteversion of femoral neck, we could not place the screws through the nail. Four months after the index surgery, collapse of femoral head and loosening of screws have occurred. MRI showed the collapse of femoral head and posttraumatic avascular necrosis. Prominent bony beak of femoral neck were identified and he complained difficulty and pain on his hip during abduction. We left two screws for secure fixation and resected the bony beak using arthroscopic burr. After the surgery, he felt free from the pain on abduction of hip. Discussion. Even though collapse of the femoral head is identified, early intervention by the arthroscopy could minimize pain or delay the progression of arthritic change. Authors think that it might be helpful for the young adult patients in terms of pain relief and potential delay of the total hip arthroplasty

Purpose. Placement of the acetabular cup in accurate and optimal position is important in total hip arthroplasty (THA) to obtain satisfactory result. On the other hand, inaccurate manual cup placement with conventional cup placement guide was reported. We therefore have been applied the mechanical acetabular alignment guide for accurate cup placement. The purpose of this study was to validate the accuracy of the acetabular alignment guide for total hip arthroplasty. Materials and methods. Between 2003 and 2014, 52 primary THAs were performed in 48 patients with using the acetabular alignment guide by one surgeon (HT). There were 42 female and 6 male with a mean age at operation of 71.1 years old (47 to 91). The original diagnosis were osteoarthritis in 43 patients (46 hips), and avascular necrosis of femoral head in 5 patients (6 hips). Used acetabular implants were Stryker® Trident AD HA cup in 24 hips and Wright medical® Acetabular Cup System in 28 hips. After completion of anesthesia, half pins were inserted at the both anterior superior iliac spine vertically and the frame was attached to the pins horizontally in supine position. Then, the patients were placed in lateral decubitus position. Finally, the alignment rod, which indicated the optimal direction of the cup (abduction angle 40°, ante-version angle 20°), was connected to the frame. All operations were done by postero-lateral approach. Assessment of the cup abduction angle and ante-version angle was performed by Lewinnek's method using postoperative AP radiograph in supine position. Results. The average cup abduction angle was 41.9±6.1° and ante-version angle was 15.2±4.1° (corrected ante-version angle was 20.2±4.1°). In 49 hips (94%) out of 52 hips, cup was placed within safe zone which was described by Lewinnek (from 30° to 50° of abduction angle, from 5° to 25° of ante-version angle). We had only 3 outliers which abduction angles were 25, 27, and 52 degrees. In terms of the ante-version angle, there was no outlier. Discussion. Our study showed that acetabular alignment guide could help accurate cup placement in THA. To hold the patients in true lateral decubitus position during THA is quite difficult and pelvis can tilt intraoperatively, sometimes resulting in malposition of the cup. The acetabular alignment guide used in this study was stabilized firmly to both iliac crests with two half pins of external fixator. Once we attach a cup angle guide to the acetabular guide frame in supine position, we can know the exact direction for cup placement without being affected by change of the pelvic orientation. We conclude that the acetabular alignment guide is useful tool in case of lateral decubitus position for THA

Dislocation after total hip arthroplasty (THA) is one of the most serious complications. We recently modified the design of Lateral Flare femoral component (RevelationV2) with six degrees lower anteversion to reproduce the normal hip condition in Japanese. In addition, we added 10-degree slope on the posterior neck to prevent dislocation especially aimed to high anteversion cases. The purpose of this study is to verify the clinical outcome after this design modification. Hospital records and database were retrospectively reviewed. We investigated 46 consecutive hips in 43 patients who underwent primary total hip arthroplasty using RevelationV2 from September 2007 to August 2009. All patients implicated preoperative planning using CAT scan with their informed consents. The mean age and BMI at surgery were 63 years old and 23.1. Preoperative diagnosis was osteoarthritis (40/46: 87%), rheumatoid arthritis (2/46: 4%) or avascular necrosis of femoral head (4/46: 9%). There were 41 hips (89.2%) of Crowe I, 3(6.5%) of Crowe II and 2(4.3%) of Crowe III. Preoperative femoral neck anteversion averaged 28 degrees, whereas postoperative combined anteversion (the sum of femoral neck anteversion and anterior cup inclination) averaged 46 degrees. During follow up, 5 complications, in details, 3 mild peroneal nerve palsy, 1 pulmonary embolism and 1 dislocation following deep infection were reported. In conclusion, although no ordinal dislocation was found in this series, longer observation will need to judge appropriateness of this new component

Introduction. Perthes disease is associated with coxa breva, plana and magna, and a high riding prominent greater trochanter causing abductor shortening and weakness, leg shortening and extra-articular impingement. A trochanteric advancement with an infero-lateralizing sliding osteotomy of the proximal femur would lengthen femoral neck, improve abductor length and strength, relieve impingement and improve leg length. We assessed the mid-term outcomes for this procedure. Method. We included patients who underwent the operation by the senior author (JNOH) with more than 2 years follow-up. The osteotomies were performed under image intensifier guidance and fixed with blade plate or locking plates. We assessed functional scores, radiological changes in neck length, Tonnis grading for arthritis and evidence of progression in femoral head avascular necrosis, time interval for conversion to hip arthroplasty and associated complications. Results. Twenty four patients (25 hips) underwent the procedure at mean age of 18.7 years (range:9.3–38.8) with a mean follow-up of 5 years (range:2–13.8). At the last assessment, the mean Oxford Hip Score was 41.6 (range:58–27), Non-Arthritic Hip Score was 53.4 (range:25–77) and UCLA activity score was 4.2 (range:2–6). For changes in neck length, the mean “Head-centre-to-Greater-trochanteric-tip-distance” was 60 mm (range:43–78) compared to 39 mm (range:30–48) pre-operatively and the mean “Head-center-to-Lesser-trochanteric-tip-distance” was 54 mm (range:47–64) compared to 37 mm (range:31–41) pre-operatively. The mean Tonnis grade was 1.5 (range:1–3) compared to 1.3 (range:1–2) pre-operatively. Two patients underwent arthroplasty conversion at 2 and 13.8 years later. One patient needed head-neck debridement for impingement and 2 patients underwent trochanteric refixation for non-union. There was no progression in avascular necrosis of femoral head. Discussion. Symptomatic Perthes hip deformity in adolescents and young adults is difficult to treat with joint preserving surgery. The mid-term clinical, functional and radiological results for double proximal femur osteotomy are encouraging

Introduction. Venous thromboembolism (VTE) is one of the common complications after total hip replacements (THRs). To reduce the risk of VTE, early rising, active movement of the foot, the use of a foot pump or graduated compression stockings and prophylactic administration of anticoagulant drugs are important. Further, intraoperative factors should be taken intoãζζconsideration. Objective. The objective of this study is to assess the influence of surgical approaches, which are a modified Watson-Jones approach and a posterolateral approach, on the frequency of VTE after primary THRs. Materials and Methods. One hundred seventy-five patients underwent 199 primary total hip replacements by a single surgeon using modified Watson-Jones approach between gluteus medius muscle and tensor fascia lata (AL Group). The average age at the operation was 63.4 ±12.5 years old. The average BMI was 23.6±3.6. The original diagnosis consisted of 151 cases of osteoarthritis of the hip, 34 cases of avascular necrosis of the femoral head, 7 cases of rheumatoid arthritis and two cases of rapidly destructive coxopathies. Control group was 159 primary total hip replacements by a single surgeon using posterolateral approach (PL Group). The average age at the operation was 63.0±11.3 years old. The average BMI was 22.8±3.6. The original diagnosis consisted of 130 cases of osteoarthritis of the hip, 17 cases of avascular necrosis of the femoral head, 7 cases of rheumatoid arthritis and four cases of rapidly destructive coxopathies. VTE was detected by contrast computed tomography or ultrasound, and soluble fibrin monomer complex (SF) was measured on the first day after surgery. Results. The frequency of VTE was thirty three of 199 cases (16.6%) in the AL Group. On the other hand, the frequency of VTE was sixty three of 159 cases (39.6%) in the PL Group. The average value of SF on the first day after surgery was 16.1±28.1 in the AL Group, 15.4±20.6 in the PL Group, respectively. In each group, the SF values showed a significant difference between VTE detected cases (41.7±55.3 in the AL Group; 24.2±26.4 in the PL Group) and VTE non-detected ones (10.9±13.6 in the AL Group; 9.4±12.4 in the PL Group) by Mann-Whitney U test. Conclusion. Modified Watson-Jones approach is useful to reduce the risk of VTE, compared with posterolateral approach. The foot position to obstruct blood flow during THRs using poterolateral approach may be the risk factor for VTE