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The Bone & Joint Journal
Vol. 105-B, Issue 10 | Pages 1123 - 1130
1 Oct 2023
Donnan M Anderson N Hoq M Donnan L

Aims. The aim of this study was to investigate the agreement in interpretation of the quality of the paediatric hip ultrasound examination, the reliability of geometric and morphological assessment, and the relationship between these measurements. Methods. Four investigators evaluated 60 hip ultrasounds and assessed their quality based the standard plane of Graf et al. They measured geometric parameters, described the morphology of the hip, and assigned the Graf grade of dysplasia. They analyzed one self-selected image and one randomly selected image from the ultrasound series, and repeated the process four weeks later. The intra- and interobserver agreement, and correlations between various parameters were analyzed. Results. In the assessment of quality, there a was moderate to substantial intraobserver agreement for each element investigated, but interobserver agreement was poor. Morphological features showed weak to moderate agreement across all parameters but improved to significant when responses were reduced. The geometric measurements showed nearly perfect agreement, and the relationship between them and the morphological features showed a dose response across all parameters with moderate to substantial correlations. There were strong correlations between geometric measurements. The Graf classification showed a fair to moderate interobserver agreement, and moderate to substantial intraobserver agreement. Conclusion. This investigation into the reliability of the interpretation of hip ultrasound scans identified the difficulties in defining what is a high-quality ultrasound. We confirmed that geometric measurements are reliably interpreted and may be useful as a further measurement of quality. Morphological features are generally poorly interpreted, but a simpler binary classification considerably improves agreement. As there is a clear dose response relationship between geometric and morphological measurements, the importance of morphology in the diagnosis of hip dysplasia should be questioned. Cite this article: Bone Joint J 2023;105-B(10):1123–1130


Bone & Joint Research
Vol. 4, Issue 12 | Pages 190 - 194
1 Dec 2015
Kleinlugtenbelt YV Hoekstra M Ham SJ Kloen P Haverlag R Simons MP Bhandari M Goslings JC Poolman RW Scholtes VAB

Objectives. Current studies on the additional benefit of using computed tomography (CT) in order to evaluate the surgeons’ agreement on treatment plans for fracture are inconsistent. This inconsistency can be explained by a methodological phenomenon called ‘spectrum bias’, defined as the bias inherent when investigators choose a population lacking therapeutic uncertainty for evaluation. The aim of the study is to determine the influence of spectrum bias on the intra-observer agreement of treatment plans for fractures of the distal radius. Methods. Four surgeons evaluated 51 patients with displaced fractures of the distal radius at four time points: T1 and T2: conventional radiographs; T3 and T4: radiographs and additional CT scan (radiograph and CT). Choice of treatment plan (operative or non-operative) and therapeutic certainty (five-point scale: very uncertain to very certain) were rated. To determine the influence of spectrum bias, the intra-observer agreement was analysed, using Kappa statistics, for each degree of therapeutic certainty. . Results. In cases with high therapeutic certainty, intra-observer agreement based on radiograph was almost perfect (0.86 to 0.90), but decreased to moderate based on a radiograph and CT (0.47 to 0.60). In cases with high therapeutic uncertainty, intra-observer agreement was slight at best (-0.12 to 0.19), but increased to moderate based on the radiograph and CT (0.56 to 0.57). Conclusion. Spectrum bias influenced the outcome of this agreement study on treatment plans. An additional CT scan improves the intra-observer agreement on treatment plans for a fracture of the distal radius only when there is therapeutic uncertainty. Reporting and analysing intra-observer agreement based on the surgeon’s level of certainty is an appropriate method to minimise spectrum bias. Cite this article: Bone Joint Res 2015;4:190–194


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_22 | Pages 13 - 13
1 Dec 2017
Jenny J Matter-Parrat V Ronde-Oustau C
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Aim. Whether pre-operative microbiological sampling contributes to the management of chronic peri-prosthetic infection remains controversial. We assessed agreement between the results of pre-operative and intra-operative samples in patients undergoing single-stage prosthesis exchange to treat chronic peri-prosthetic infection. The tested hypothesis was that agreement between pre-operative and intra-operative samples exceeds 75% in patients undergoing single-stage exchange of a hip or knee prosthesis to treat chronic peri-prosthetic infection. Method. This single-centre retrospective study included 85 single-stage prosthesis exchange procedures in 82 patients with chronic peri-prosthetic infection at the hip or knee. Agreement between pre-operative and intra-operative sample results was evaluated. Changes to the initial antibiotic regimen made based on the intra-operative sample results were recorded. Associations between sample agreement and infection-free survival were assessed. Results. Of 149 pre-operative samples, 109 yielded positive cultures, in 75/85 cases. Of 458 intra-operative samples, 354 yielded positive cultures, in 85/85 cases. Agreement was complete in 54 (63%) cases and partial in 9 (11%) cases; there was no agreement in the remaining 22 (26%) cases. The complete agreement rate was significantly lower than 75% (p=0.01). The initial antibiotic regimen was inadequate in a single case. Agreement between pre-operative and intra-operative samples was not significantly associated with infection-free survival. Conclusions. Pre-operative sampling may contribute to the diagnosis of peri-prosthetic infection but is neither necessary nor sufficient to confirm the diagnosis and identify the causative agent. The spectrum of the initial antibiotic regimen cannot be safely narrowed based on the pre-operative sample results. We suggest the routine prescription of a probabilistic broad-spectrum antibiotic regimen immediately after the prosthesis exchange, even when a pathogen was identified before surgery. No funding from any part was received for the purpose of this study


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 553 - 553
1 Oct 2010
Malek I Hyder N Machani B Mevcha A
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Introduction: Large numbers of studies have been conducted to help the decision making of appropriate management of an ankle fracture. Aim: To assess intra-observer and inter-observer agreement of treatment for ankle fracture based on plain radiographs. Materials and Methods: Fifty patients with ankle fracture were randomly selected. Antero-posterior and lateral view ankle radiographs were blinded by the first author and then reviewed by five orthopaedic surgeons with varying clinical experience. The observers were asked for their opinion about how they would like to treat the fracture? They were provided with additional basic information of patient age, sex, mechanism of injury and associated comorbidities. This exercise was repeated again after four weeks. The kappa coefficient and observed agreement values were used for statistical analysis. Results: The kappa values on both occasions were 0.41(SE: 0.084, 95% Confidence interval: 0.248–0.576, P< 0.00001) and 0.29(SE: 0.099, 95% confidence interval: 0.098 TO 0.487, P< 0.00001). These results show only fair inter-observer agreement. The kappa values for intra-observer agreement were from 0.34 to 0.69 (P< 0.001) for different observers. The observed agreement for these observers was from 70% to 94%. Only two most senior observers had good agreement. Conclusion: These results show that there is only fair inter-observer agreement of the treatment for ankle fracture based on plain radiographs and only senior clinicians were consistent about their preferred mode of treatment on both occasions. There is a need of clear guidelines and better understanding of biomechanics of Ankle Fractures to minimize the ‘grey’ zone of when to intervene


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_4 | Pages 4 - 4
1 Feb 2014
Stynes S Konstantinou K Dunn K Lewis M Hay E
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Background. Pain with radiation to the leg is a common presentation in back pain patients. Radiating leg pain is either referred pain or radicular, commonly described as sciatica. Clinically distinguishing between these types of leg pain is recognized as difficult but important for management purposes. The aim of this study was to investigate inter-therapist agreement when diagnosing referred or radicular pain. Methods. Thirty-six primary care consulters with low back-related leg pain were assessed and diagnosed as referred or radicular leg pain by one of six trained experienced musculoskeletal physiotherapists. Assessments were videoed, excluding any diagnosis discourse, and viewed by a second physiotherapist who made an independent diagnosis. Therapists rated their confidence with diagnosis and reasons for their decision. Data was summarized using percentage agreements and kappa (K) coefficients with two sided 95% confidence intervals (CI). Results. The therapists assessing and therapists watching the video both diagnosed radicular pain in 25 of the 36 patients. Agreement was 72% with fair inter-rater reliability (K = 0.35, 95% CI 0.07, 0.63, p<0.05). Mean confidence in diagnosis was 87% for radicular pain and 83% for referred pain. In the subgroup of patients where therapists' confidence in diagnosis was ≥ 80% (n=28), agreement was 86% with substantial reliability (K = 0.65, 95% CI 0.37, 0.93 p<0.001). Conclusion. Reliability was fair among therapists when diagnosing back-related leg pain. This concurs with current opinion that differentiating between types of back-related leg pain can be difficult. However, when confidence in clinical diagnosis is high, levels of agreement and reliability indices improve substantially


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 17 - 17
1 Mar 2009
Poolman R Keijser L de Waal Malefijt M Blankevoort L Farrokhyar F Bhandari M
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Background: The selection of presentations at orthopedic meetings is an important process. If the peer reviewers do not consistently agree on the quality score, the review process is arbitrary and open to bias. The aim of this study was:. 1) To describe the inter reviewer agreement of a previously designed scoring scheme to rate abstracts submitted for presentation at the Dutch Orthopedic Association. 2) To test if quality of reporting of submitted abstracts increased in the years after the introduction of the scoring scheme. 3) To examine if a review process with a larger workload had lower inter rater agreement. Methods: We calculated intraclass correlation coefficients (ICC) to measure the level of agreement among reviewers using the International Society of the Knee (ISK) abstract quality of reporting system. Acceptance rate and quality of the abstracts are described. Results: Of 419 abstracts 229 (55%) were accepted. Inter-reviewer agreement to rate abstracts was substantial 0.68 (95%CI 0.47, 0.83) to almost perfect 0.95 (95%CI 0.92, 0.97) and did not change over the eligible time period. Less abstracts were accepted after 2004 (p = 0.039). The mean ISK abstract score, maximally 100 points, for accepted abstracts ranged from 60.4 (95%CI 57.7, 63.0) to 63.8 (95% CI 62.0, 65.7). The mean ISK abstract score for rejected abstracts varied from 45.8 (95%CI 40.3, 51.2) to 50.6 (95% CI 46.5, 54.8). Both scores for accepted and rejected abstracts did not change over time. Workload of the reviewers did not influence their level of agreement (p=0.167). Interpretation: The ISK abstract rating system has an excellent inter observer agreement. Other scientific orthopedic meetings could adopt this ISK rating system for further evaluation in local or international setting


The Journal of Bone & Joint Surgery British Volume
Vol. 70-B, Issue 2 | Pages 299 - 301
1 Mar 1988
Dias J Taylor M Thompson J Brenkel I Gregg P

Inter-observer agreement and reproducibility of opinion were assessed for the radiographic diagnosis of union of scaphoid fractures on films taken 12 weeks after injury. Weighted kappa statistics were used to compare the opinions of eight senior observers reviewing 20 sets of good quality radiographs on two occasions separated by two months. There was poor agreement on whether trabeculae crossed the fracture line, whether there was sclerosis at or near the fracture and on whether the proximal part of the scaphoid was avascular. As a consequence, agreement on union also was poor; it appears that radiographs taken 12 weeks after a scaphoid fracture do not provide reliable and reproducible evidence of healing


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_11 | Pages 315 - 315
1 Jul 2014
Dhooge Y Wentink N Theelen L van Hemert W Senden R
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Summary. The ankle X-ray has moderate diagnostic power to identify syndesmotic instability, showing large sensitivity ranges between observers. Classification systems and radiographic measurements showed moderate to high interobserver agreement, with extended classifications performing worse. Introduction. There is no consensus regarding the diagnosis and treatment of ankle fractures with respect to syndesmotic injury. The diagnosis of syndesmotic injury is currently based on intraoperative findings. Surgical indication is mainly made by ankle X-ray assessment, by several classification systems and radiographic measurements. Misdiagnosis of the injury results in suboptimal treatment, which may lead to chronic complaints, like instability and osteoarthritis. This study investigates the diagnostic power and interobserver agreement of three classification methods and radiographic measures, currently used to assess X-ankles and to identify syndesmotic injury. Patients and Methods. Twenty patients (43.2 ± 15.3yrs) with an ankle fracture, indicated for surgery, were prospectively included. All patients received a preoperative ankle X-ray, which was assessed by several observers: two orthopaedic surgeons, one trauma surgeon and two radiologists. The ankle X-ray was assessed on syndesmotic injury/stability and presence of fractures (fibula, medial/tertius malleolus). Three classification systems were used: Weber, AO-Müller (short-version n=3 options; extended-version n=27 options), Lauge-Hansen (short-version n=5 options; extended-version n=17 options) and two radiographic measurements were done: tibiofibular overlap (TFO) and ratio medial clearspace/superior clear space (MCS/SCS). All observers were instructed about the assessments before the measurements. During surgery, a proper intraoperative description of the syndesmosis was noted. Agreement (%), Intraclass Correlation Coefficients (ICC) and Kappa were calculated to determine interobserver agreement. Kappa statistic was interpreted according to Landis and Koch. To test the diagnostic power of ankle X-rays to identify syndesmotic instability, sensitivity and specificity were calculated with intraoperative findings serving as golden standard. Results. Six of 20 ankles showed syndesmotic instability intraoperatively. An overall sensitivity of 43% (specificity: 78) was found for X-rays in identifying syndesmotic instability, showing a wide range in sensitivity between observers (17–83%), with radiologists performing better (range 50–83%) than surgeons (range: 17–33%). Overall, substantial to perfect interobserver agreement (range 70–100%) was found for all short classification systems, showing an average kappa ≥0.60. The agreement reduced for more extended classification systems. E.g. observer agreement for the AO-Muller classification with 3, 9 and 27 options was respectively 85% (kappa 0.66), 68% (kappa 0.57) and 55% (kappa 0.51). One observer deviated slightly from others in all classification assessments. Removing this observer resulted in excellent agreement for all classification systems (>90%). Radiographic measurements showed moderate to high interobserver agreement, with TFO performing best (avg. ICC 0.88). Discussion/Conclusion. In ankle fractures, a preoperative X-ray has low sensitivity in detecting syndesmotic instability, showing large sensitivity ranges between observers. Further study is needed to investigate the contribution of classification systems in determining the best treatment method for syndesmotic injury. Ankle X-ray assessment using the three classification systems and radiographic measures was consistent among observers. Disagreement between observers can be attributed to intrinsic differences among the systems (e.g. stepwise classification vs. single assessment). No preference for one specific classification was found, as all showed comparable interobserver agreement. However classification systems with few options are recommended, as the observer agreement reduced with more extending classifications


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 171 - 171
1 Mar 2006
Sanchez R Salcedo C Martinez M Molina J Vera F Villarreal J
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Introduction and objectives: The purpose of the research is to show the agreement and reproducibility among 5 observers when they are questioned about 51 open fractures using two open fracture classifications for long bones (Gustilo and Aybar), interpreting the results obtained between both classifications. Material and Method: A classification protocol is established for open fractures. The fractures are graded independently using each of the systems being evaluated (Gustilo and Aybar), by visualising slides with clinical and radiologic images in addition to a report of the data in the clinical history. The survey is conducted twice with a time difference of one to eight weeks. 5 members of the Orthopedic and Traumatologic Surgery Department (OTSD) were questioned (1 Professor, 2 Specialists and 2 Residents). The statistical method used to analyse the results was the interobserver agreement percentage and the inter- and intraobserver kappa index. Results: The interobserver agreement percentage for the Gustilo classification was 58.82% and 39.21% for the Aybar classification. The kappa index for the interobserver agreement for the Gustilo classification was 0.51 and for the Aybar classification was 0.54. The kappa index for the intraobserver reproducibility was 0.69 for the Gustilo classification and 0.58 for the Aybar one. Conclusions: The interobserver agreemnet was considered moderate-poor for the Gustilo and Aybar classifications. The intraobserver reproducibility was considered substantial for the Gustilo classification and moderate for the Aybar one. We conclude that this agreement shows too much variability as to accept just one classification as the only valid method to take therapeutic decisions or for comparing results. Therefore, it’s necessary to create a more detailed and careful classification, which is quick to use, reliable, reproducible and which contains a more objective criteria


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 245 - 245
1 May 2009
Davidson D Beauchamp R Ghag R Mulpuri K Tredwell SJ
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Avascular necrosis (AVN) of the femoral head is a devastating complication of slipped capital femoral epiphysis (SCFE). The reported prevalence of AVN following unstable SCFE has ranged between fifteen and forty-seven per cent in the literature. The explanation for this discrepancy is not clear. The inter-observer and intra-observer agreement between Orthopaedic surgeons for the radiographic diagnosis of AVN following SCFE has not been reported. It is the objective of this study to estimate these parameters between two experienced pediatric Orthopaedic surgeons for the radiographic diagnosis of AVN following SCFE. A retrospective review of all one hundred and three cases of SCFE treated at a Canadian pediatric referral center between 1995 and 2005 was performed. Of these, eight were diagnosed, by the treating surgeon, with AVN. Each of these eight children and a random sample of fifteen of the remaining children, who were not diagnosed with AVN, were included in this study. The most recent anteroposterior and lateral radiographs were digitised and presented to two experienced pediatric orthopaedic surgeons in a blinded, random order. Each surgeon reviewed the radiographs independently and recorded which radiographs they believed to be consistent with AVN. The surgeons were told that each patient had SCFE and that some developed AVN, however neither the classification of the slip, nor the proportion who developed AVN were divulged. Each observer repeated this process two weeks after the initial review in order to determine intra-observer agreement. The kappa value was determined to assess inter-observer and intra-observer agreement. The first observer recorded eight cases of AVN at the initial and seven cases at the second observation time. The intra-observer agreement was 0.9. The second observer recorded six cases of AVN at the initial and five cases at the second observation time. The intra-observer agreement was 0.88. The inter-observer agreement was determined at the first observation time and was 0.79. On the basis of the results of this study, both the inter-observer and intra-observer agreement for the radiographic diagnosis of AVN following SCFE, amongst experienced pediatric Orthopaedic surgeons, was very high. It is unlikely that the reported discrepancy in prevalence of AVN following SCFE is due to a lack of inter-observer agreement, on the basis of the findings of this study. The inter-observer agreement between less experienced observers requires further study to determine if this may be the source of the variability in the reported prevalence of AVN following SCFE


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_23 | Pages 8 - 8
1 Dec 2016
Declercq P Goris S Neyt J Wauters J Spriet I
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Aim. Preoperative joint aspiration cultures (PJACs) are of great value in diagnosing prosthetic joint infections (PJIs). Studies investigating the predictive value of PJACs to identify causative pathogens in PJI, which is off course relevant for the correct initiation of antimicrobial treatment, are limited. The objective of this study was to investigate whether the PJACs are in agreement with causative pathogens in PJIs. Method. A retrospective monocentric study was conducted at the 40-bed orthopedics department of a tertiary centre. Medical files of patients with proven prosthetic knee or hip infection with PJACs from maximum 6 months prior to the first stage of a two-stage revision admitted between March 2010 and December 2014 were evaluated. A proven PJI was defined as at least two positive preoperative or intraoperative cultures, the presence of purulent synovial fluid or purulence at the implant site or surrounding the prosthesis without other identifiable causes, the presence of acute inflammation upon histopathological examination of the periprosthetic tissue at the time of surgery or the presence of a sinus tract communicating with the prosthesis. In order to identify the causative pathogen(s) per patient, a multidisciplinary team, consisting out of a microbiologist, a septic orthopedic surgeon, two infectious diseases specialists and two clinical pharmacists, assessed the relevance of pathogens cultured in the PJACs and intraoperative deep samples based on the current 2012 IDSA guidelines. Per patient, agreement of PJACs corresponding to the retained causative pathogen(s) was investigated in two ways: 1) on species level and 2) on Gram stain or fungi level. Results. Forty-six patients (66 ± 10 years; 26 males; 23 knee and 23 hip; 25 first revisions and 21 with multiple revisions) were included. PJACs remained sterile in seven patients. In 25 of 46 patients (54%) there was agreement in terms of causative pathogen species. In 39 of 46 patients (85%), there was agreement in terms of Gram staining or fungi results. In the other 7 patients, PJACs remained sterile, but with positive intraoperative culture results. Conclusions. Only half of PJAC results corresponded to the retained causative pathogens. Therefore, PJACs should not be used to initiate directed antimicrobial therapy; directed therapy should only be instituted when also intraoperatieve cultures are known. Initially, a (combination of) broad spectrum agent(s) should be preferred. Also preliminary narrowing of the spectrum can be implemented based on the Gram staining or fungi results of PJACs, as was seen in our study


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIII | Pages 149 - 149
1 May 2012
Mcdougall C Watts M Myers P Risebury M Jones M
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Many of the questionnaire based scoring systems (i.e. Rowe score) require some form of clinical assessment. These clinical components can be very difficult to perform on a large scale particularly when a patient lives a long distance from clinic. We have attempted to counter this problem by asking the patient to asses their own range of motion. The aim of this study was to test the agreement between patient and clinician measured shoulder external rotation range using a photo based self-assessment tool. Fifty-one professional and semi-professional rugby players were recruited to assess shoulder external rotation range. Each player was presented with a photo based shoulder external rotation range self-assessment tool, which featured four photos of progressive shoulder external rotation in 2 positions, 900 abduction (150, 300, 450 & 600 of external rotation) and 00 abduction (700, 800, 900 & 1000 of external rotation). The players were asked to perform active external rotation in these two positions and mark the image which best matched their maximal external rotation. The player was then independently assessed using the same tool, by a clinician. The difference between the player's and the clinician's assessment was analysed using a weighted Kappa test. The Kappa for the shoulder external rotation in 900 abduction was 0.75 and 0.71 for left and right respectively, and 0.57 and 0.55 for shoulder external rotation in 00 abduction. Thus, the strength of agreement between the player's and clinician's assessment of shoulder external rotation is good in 900 abduction and moderate in 00 abduction. These results demonstrate that the photo-based shoulder external rotation range self-assessment tool is a very useful addition to researchers' and clinicians' toolkits and may be most useful when a patient lives a great distance from/or is unable to attend a clinic


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_17 | Pages 75 - 75
24 Nov 2023
Reinert N Wetzel K Franzeck F Morgenstern M Clauss M Sendi P
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Background and aim

In 2019, specific diagnostic and antibiotic treatment recommendations for diabetic foot infection (DFI) and osteomyelitis (DFO) were introduced in our institution. They include principles on numbers of biopsies to obtain for microbiological/histopathological examinations, labeling anatomic localization, and antibiotic treatment (ABT) duration based on the aforementioned findings. ABT should be stopped after complete resection of infected bone. In case of incomplete resection, treatment is continued for 4–6 weeks. Two years after the introduction of these recommendations, we investigated the degree of implementation for hospitalized patients.

Method

Adult patients with DFI/DFO undergoing surgical intervention from 01/2019–12/2021 were reviewed retrospectively. Diagnostic procedures were assigned to each episode when performed ≤30 days before surgical invention. Chi-square and Mann-Whitney-U tests were performed where appropriate.


Bone & Joint 360
Vol. 10, Issue 6 | Pages 8 - 10
1 Dec 2021
Spacey K Wimhurst J Hasan R Sharma D


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 122 - 122
1 Sep 2012
Jensen C Overgaard S Aagaard P
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Introduction. Total leg muscle function in hip OA patients is not well studied. We used a test-retest protocol to evaluate the reproducibility of single- and multi-joint peak muscle torque and rapid torque development in a group of 40–65 yr old hip patients. Both peak torque and torque development are outcome measures associated with functional performance during activities of daily living. Material and Methods. Patients: Twenty patients (age 55.5±3.3, BMI 27.6±4.8) who underwent total hip arthroplasty participated in this study. Reliability: We used the intra-class correlation (ICC) and within subject coefficients of variation (CVws) to evaluate reliability. Agreement: Relative Bland-Altman 95% limits of agreements (LOA) and smallest detectable difference (SDD) were calculated and used for evaluation of measurement accuracy. Parameters: Maximal muscle strength (peak torque, Nm) and rate of torque development (Nm•sec-1) for affected (AF) and non-affected (NA) side were measured during unilateral knee extension-flexion (seated), hip extension-flexion, and hip adduction-abduction (standing), respectively. Contractile RTD100, 200, peak was derived as the average slope of the torque-time curve (torque/time) at 0–100, 0–200 and 0 peak relative to onset of contraction. Protocol: After 5 min level walking at self-selected and maximum speeds each muscle group was tested using 1–2 sub-maximal contraction efforts followed by 3 maximal contractions 4s duration. Statistics: The variance components were estimated using STATA12, with muscle function and occasion as independent variable and patients as random factor, using the restricted maximum likelihood method (=0.05). Results. For all exercises and sides, the ICC's for peak torque were good (0.81–0.96) with CVws ranging from 5.0–10.8%. Similar good ICC's were observed for RTD200 on the non-affected side (0.83–0.93), whereas most exercises (4/6) on the affected side showed moderate to good ICC (0.72–0.82). We found moderate CVws for RTD200 with 12.8–18.7% and 10.3–18.9%, affected and non-affected, respectively. With few exceptions the ICC's and CVws for RTD100 were moderate to poor on the affected side but good to moderate on the non-affected side. The SDD's for peak torque ranged from 14.9 Nm to 39.0 Nm, equal to relative LOA of 13.9–23.8%. For RTD200, the SDD's were 77–257 Nm•sec-1 and 29.2–86.2%, absolute and relative, respectively. With few exceptions interventions measuring RTD100 and RTDpeak would have to find changes exceeding 60% for them to be statistical significant. Conclusions. Our novel set-up for lower limb isometric muscle testing showed overall good reproducibility for peak torque, moderate for RTD200, while poor for RTD100 and RTDpeak. The results for peak torque and RTD200 are promising for defining relevant changes in muscle function in future longitudinal clinical trials in this patient group


The Journal of Bone & Joint Surgery British Volume
Vol. 30-B, Issue 1 | Pages 4 - 6
1 Feb 1948


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 197 - 197
1 Jul 2002
Liow R Rangan A
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We investigated the accuracy of clinical signs for the diagnosis of rotator cuff disease. Fifty patients with history suggestive of rotator cuff disease (subacromial impingement syndrome or rotator cuff tear) were examined by two observers to determine the accuracy of commonly used clinical tests for the condition. The observers were a consultant (cons.) with an established shoulder practice and a senior registrar (reg.) with an interest in shoulder surgery. The clinical signs of impingement syndrome we evaluated include the painful arc, the drop arm test, Neer’s sign and Hawkins’ sign. For rotator cuff pathology we evaluated the strength of abduction initiation and at 90 degrees abduction for supraspinatus, Speed’s and Yergason’s tests for biceps, strength of shoulder external rotation for infraspinatus and the Gerber lift-off test for subscapularis. We compared our clinical accuracy against a positive subacromial injection test for impingement syndrome, and the findings of rotator cuff tears at arthroscopy.

The consultant and the registrar did not differ significantly in their assessments (paired t-test, p> 0.05). The highly sensitive tests have poor specificity. The most sensitive tests for impingement syndrome were the Hawkins’ sign (cons:100%, reg: 97%) and the Neer’s sign (cons: 94%, reg: 81%). The Hawkins’ sign also had high negative and positive predictive values. The painful arc and the drop arm tests both had low sensitivity and specificity. Testing the supraspinatus strength at 90 degrees abduction was more sensitive for full thickness cuff tear than testing strength of abduction initiation (cons: 100% vs 67%; reg: 90% vs 50%). These tests were poor at differentiating partial thickness tears from full thickness tears.

Our findings echoed the conclusions of other papers in that the Neer’s and Hawkins’ signs are the most sensitive for impingement syndrome. Testing the supraspinatus at 90 degrees abduction was more sensitive than abduction initiation for full thickness supraspinatus tear.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 571 - 571
1 Nov 2011
Rouleau DM Kidder J de Villanueva JP Dynamidis S De Franco M Walch G
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Purpose: Recognition of the glenoid version is important for evaluation of different pathologies. There is no consensus on method to use to evaluate version. The purpose of this study was to compare different measurement strategies in one hundred-sixteen (116) patients with shoulder CT-scans.

Method: Scapula CT-scan axial images were revised and the cut below the base of the coracoid was selected. The glenoid version was measured according to the Friedman method (FM) and the “scapula body” methods (BM). In case of B2 glenoid three different reference lines have been measure: the neo-glenoid NG (posterior erosion surface), paleo-glenoid PG (original glenoid surface) and the intermediate-glenoid IG (line from anterior and posterior edge). Three orthopaedic surgeons independently examined the images two times and intra/inter-observer reliability was calculated using Intra-Class Correlation (ICC). The objective of this paper is to define which method shows best reliability.

Results: Group 1 (B2 excluded n=53): The average glenoid version was significantly different between two measurement techniques for all three observers, with an average of – 7.29° for BM technique and – 10.43° for FM. Intra-observer reliability was excellent for both methods (ICC: 0.958–0.979 for FM; 0.940–0.970 for BM). Inter-observer reliability was excellent for both methods (FM: ICC= 0.977; BM: ICC= 0.962). The light superiority of the first method was not significant. For group 2 – B2 glenoid (n=63): six different measures of version were taken resulting by two scapula reference line (FM and BM) and three glenoid reference line (PG, IG, NG). The average glenoid versions were significantly different (p0.82). The inter-observer reliability were also very-good or excellent for all methods (ICC > 0.79). The most reliable method for measurement of B2 glenoid version was the association of the Friedman line for the scapula axis and the intermediate glenoid line with excellent intra observer reliability (ICC > 0.957) and inter-observer reliability (ICC=0.954).

Conclusion: Measurement of glenoid version on axial cut of a Ct-scan is highly reliable. Significant differences exist between measures depending which method is used, underlying the importance of a consensus for research and clinical purpose. Despite very good performance of all methods, authors recommend the use of the Friedman method for the scapula axis reference and an intermediate glenoid line in case of B2 glenoid.


The Bone & Joint Journal
Vol. 105-B, Issue 9 | Pages 1007 - 1012
1 Sep 2023
Hoeritzauer I Paterson M Jamjoom AAB Srikandarajah N Soleiman H Poon MTC Copley PC Graves C MacKay S Duong C Leung AHC Eames N Statham PFX Darwish S Sell PJ Thorpe P Shekhar H Roy H Woodfield J

Aims. Patients with cauda equina syndrome (CES) require emergency imaging and surgical decompression. The severity and type of symptoms may influence the timing of imaging and surgery, and help predict the patient’s prognosis. Categories of CES attempt to group patients for management and prognostication purposes. We aimed in this study to assess the inter-rater reliability of dividing patients with CES into categories to assess whether they can be reliably applied in clinical practice and in research. Methods. A literature review was undertaken to identify published descriptions of categories of CES. A total of 100 real anonymized clinical vignettes of patients diagnosed with CES from the Understanding Cauda Equina Syndrome (UCES) study were reviewed by consultant spinal surgeons, neurosurgical registrars, and medical students. All were provided with published category definitions and asked to decide whether each patient had ‘suspected CES’; ‘early CES’; ‘incomplete CES’; or ‘CES with urinary retention’. Inter-rater agreement was assessed for all categories, for all raters, and for each group of raters using Fleiss’s kappa. Results. Each of the 100 participants were rated by four medical students, five neurosurgical registrars, and four consultant spinal surgeons. No groups achieved reasonable inter-rater agreement for any of the categories. CES with retention versus all other categories had the highest inter-rater agreement (kappa 0.34 (95% confidence interval 0.27 to 0.31); minimal agreement). There was no improvement in inter-rater agreement with clinical experience. Across all categories, registrars agreed with each other most often (kappa 0.41), followed by medical students (kappa 0.39). Consultant spinal surgeons had the lowest inter-rater agreement (kappa 0.17). Conclusion. Inter-rater agreement for categorizing CES is low among clinicians who regularly manage these patients. CES categories should be used with caution in clinical practice and research studies, as groups may be heterogenous and not comparable. Cite this article: Bone Joint J 2023;105-B(9):1007–1012


Bone & Joint Research
Vol. 13, Issue 1 | Pages 19 - 27
5 Jan 2024
Baertl S Rupp M Kerschbaum M Morgenstern M Baumann F Pfeifer C Worlicek M Popp D Amanatullah DF Alt V

Aims. This study aimed to evaluate the clinical application of the PJI-TNM classification for periprosthetic joint infection (PJI) by determining intraobserver and interobserver reliability. To facilitate its use in clinical practice, an educational app was subsequently developed and evaluated. Methods. A total of ten orthopaedic surgeons classified 20 cases of PJI based on the PJI-TNM classification. Subsequently, the classification was re-evaluated using the PJI-TNM app. Classification accuracy was calculated separately for each subcategory (reinfection, tissue and implant condition, non-human cells, and morbidity of the patient). Fleiss’ kappa and Cohen’s kappa were calculated for interobserver and intraobserver reliability, respectively. Results. Overall, interobserver and intraobserver agreements were substantial across the 20 classified cases. Analyses for the variable ‘reinfection’ revealed an almost perfect interobserver and intraobserver agreement with a classification accuracy of 94.8%. The category 'tissue and implant conditions' showed moderate interobserver and substantial intraobserver reliability, while the classification accuracy was 70.8%. For 'non-human cells,' accuracy was 81.0% and interobserver agreement was moderate with an almost perfect intraobserver reliability. The classification accuracy of the variable 'morbidity of the patient' reached 73.5% with a moderate interobserver agreement, whereas the intraobserver agreement was substantial. The application of the app yielded comparable results across all subgroups. Conclusion. The PJI-TNM classification system captures the heterogeneity of PJI and can be applied with substantial inter- and intraobserver reliability. The PJI-TNM educational app aims to facilitate application in clinical practice. A major limitation was the correct assessment of the implant situation. To eliminate this, a re-evaluation according to intraoperative findings is strongly recommended. Cite this article: Bone Joint Res 2024;13(1):19–27