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Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_32 | Pages 10 - 10
1 Sep 2013
Guyver P Hill JH DeBeer J Murphy A
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The aim of this audit was to assess the union rate of humeral shaft fractures treated conservatively in a functional brace in our unit, compared to a “gold standard” of 98% as reported by Sarmiento (JBJS 1977).

A retrospective clinical and radiographic review of 155 closed humeral shaft fractures managed with a humeral brace from 2005–2012 was performed. Pathological fractures and patients under 18 were excluded. The mean age was 60 (18–94) with 45 males and 72 females. 15 (10%) patients under 18 and 8 (5%) pathological fractures were excluded; 15 (10%) patients were lost to follow up.

Of the remaining 117 fractures, 83 (71%) went on to union and 34 (29%) developed a non-union. Mean time to union was 131 days (47–622). 80% of distal fractures and 75% of midshaft fractures united but only 58% of proximal fractures went on to unite. There was no significant difference in union rates between multi fragmentary (> 3 parts) and simple fracture patterns (69% vs 71% respectively).

Our study suggests that a lower threshold for operative intervention of proximal third humeral shaft fractures may be required.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 137 - 137
1 Mar 2010
Williams D Petruccelli D Winemaker M deBeer J
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Purpose: Medical research has classically been based on the male model, this is no different in the design of arthroplasty implants. Focus has recently shifted to gender-specific implant design but evidence is just developing in the literature as to gender specific outcomes. We hypothesised that outcomes in arthroplasty patients are affected by gender.

Methods: Patients were retrospectively identified from a prospectively collected database of total joint arthroplasties performed at one center. Six surgeons performed 1123 primary unilateral cemented TKA’s, and 989 primary unilateral cementless THA’s over a period of seven years. General demographic data was collected along with preoperative and 1-year clinical outcomes including the Harris Hip/Knee Society Score and Oxford Hip/Knee scores. These were compared to determine differences, if any, between males and females using independent samples t-test.

Results: The TKA sample was comprised of 540 (55%) females and 449 (45%) males. The THA sample included 744 (66%) females and 379 (34%) males.

In the TKA group, females were significantly younger, had higher BMI and had differing rates of comorbidities and complications. Female KSS, Oxford and ROM outcomes were significantly inferior to male scores preoperatively and at 1 year follow up. Significantly more females reported higher pain scores than males from pre-op to 1 year. Interestingly, females showed significantly more improvement from pre-op to 1 year in both scores.

In the THR group there were varying rates of complications and comorbidities by gender. Females did significantly worse in the HHS and Oxford hip score from pre-op until one year when results equalized. Similarly pain scores were higher for females preop and at 6 weeks but became equivalent thereafter. Females showed significantly greater improvements from pre-op to 1 year in both outcome scores.

Conclusion: As reported in the literature, results of this study indicate that women choose TJR at a later stage of disease than men do, presenting with inferior functional status. The effect of waiting seems most marked in the knee arthroplasty population with inferior outcomes and pain relief persisting out to 1 year. Surgeons must counsel females differently about expectations and recovery in joint arthroplasty.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 39 - 39
1 Mar 2008
Kaspar S deBeer J Petrucelli D
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There has never been a study of whether intra-articular steroid injections of arthritic hips can alter the outcomes of subsequent arthritis management, particularly total hip arthroplasty (THA). In this study forty patients with a history of steroid injection of the hip and subsequent THA are examined retrospectively for infections, revisions, and prospectively-gathered hip scores, as compared to matched non-steroid controls. The steroid group had an increased incidence of pain, infectious workup under usual care, and two revisions for deep infection within three years. We suggest that steroid injections of hips should be avoided in patients who are candidates for THA.

Despite the lack of demonstrated efficacy of intra-articular steroid injections for hip arthritis, the procedure is often utilized for diagnostic differentiation from spine pain, and attempted therapeutic management of painful hip arthritis. However, in the era of total hip arthroplasty (THA) the safety of this practice must be evaluated in the context of whether the injections pose any potential for complicating subsequent surgery, particularly with regard to infection. In this study, forty patients who underwent THA and had a history of previous steroid injection were compared retrospectively to forty carefully-matched patients who underwent THA in the same time period but had no history of prior steroid injection. Outcome measures included whether there was a septic workup under usual care, and this occurred in 20% of steroid patients within the first thirty-six months post-THA, as opposed to 0% in the controls. Furthermore, in a detailed analysis of Harris and Oxford scores, there was in the steroid group a higher incidence of night pain, increased severity of pain, and reduced function with activities of daily living at one year. There were two revisions for deep infection in the steroid group, and one revision for dislocation in each of the steroid and control groups. Pending the completion of the study, we provisionally suggest that steroid injection of hips may be ill-advised in a patient who will be a candidate for THA in the future. This suggestion is based primarily on the incidence of pain and infectious complications in the first postoperative year.

Funding Dr Kaspar holds academic research grants from McMaster University and from The Physicians’ Services Incorporated (PSI) Foundation, the latter of which was used to finance this study and the continuation thereof. There are no commercial grants or conflicts of interest.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 84 - 84
1 Mar 2008
Gamble P deBeer J Winemaker M Farrokhyar F Petruccelli D Kaspar S
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Failed open reduction internal fixation (ORIF) of the proximal femur can render patients severely disabled. This study analyzed the short-term functional results and complications of total hip arthroplasty (THA) for complications of ORIF of the proximal femur. Using the Hamilton Arthroplasty Database, thirty-six patients treated with a THA for complications of ORIF of the proximal femur were compared to a matched cohort. Analysis showed that THA for complications of ORIF of the proximal femur is a successful procedure despite increased intraoperative difficulty that results in comparatively lower short-term Harris Hip Scores. No statistically significant differences in intraoperative or postoperative complications were noted.

Open reduction internal fixation (ORIF) of the proximal femur is a common, successful orthopedic procedure. However, failed ORIF of the proximal femur can render patients severely disabled. The purpose of this study is to analyze and compare the short-term functional results and complications of total hip arthroplasty (THA) for complications of ORIF of the proximal femur.

After ethics approval, the Hamilton Arthroplasty Registry, a prospective database, was used to identify thirty-seven patients treated with THA for complications of ORIF of the proximal femur. From September 1998 to the present a group consisting of sixteen males and twenty females, with a mean age of sixty-seven, were matched to a cohort of patients treated with a primary THA. Using Wilcoxon Test and Chi-Square Tests, the two groups were compared (p< 0.05).

Initially, ORIF was used to treat thirty-six patients for proximal femur fracture. The mean follow-up was 13.5 months. The experimental group had a significantly lower (p=0.035) Harris Hip Score at the one year follow-up, however both groups showed a significant improvement from preoperative scores (p=0.0001). A significant difference was noted between the two groups in estimated blood loss (p=0.01) and operative time (p=0.01). There was no significant difference in complication rate.

THA for complications of ORIF of the proximal femur is a successful procedure improving patient’s pain and functional status. This is a more complicated procedure than primary THA, at times requiring the use of a revision stem, which results in significantly lower Harris Hip Scores. Nonetheless, there appears to be no comparative increase in short-term complications.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 362 - 363
1 Sep 2005
Kaspar S Kaspar J Orme C deBeer J
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Introduction and Aims: Intra-articular steroid hip injection (IASHI) has been extensively administered for painful hip arthritis since the 1950s, but with advances in medical and surgical management, its role is less certain today. There is very little published data on the utility or prescribing patterns of IASHI.

Method: A questionnaire seeking expert opinions on IASHI was developed and distributed to practising Ontario-based members of the Canadian Orthopaedic Association. Initial phone calls identified those who perform hip replacements, and subsequent faxed forms had a 73% response rate (99 surgeons). We systematically describe the current practices and expert opinions of 99 hip surgeons, on the use of IASHI, focusing on indications, current usage, and complications.

Results: Only 56% of surgeons felt that IASHI was actually useful therapeutically, though four in five surgeons cited the usefulness of hip injection for differentiating hip-spine co-morbidity in diagnostically challenging patients. Therapeutic benefit from IASHI was perceived to be poor, with 72% of surgeons estimating that between zero and 60% of their patients achieved any benefit at all from the injections, with duration of benefit uniformly estimated as being between zero and six months. Infection rates were considered to be less than 2% by most surgeons. One quarter of the surgeons felt that IASHI accelerates arthritis progression, most of whom had stated that it would be no great loss if IASHI was no longer available. Nineteen percent of the surgeons believed that there may be increased infection rate of THA after IASHI, and this was associated with lower numbers of IASHI ordered per year, compared to those who did not feel that infection rates would increase. The opinions of this large group of experts is consistent with efficacy studies, and forms a context for our ongoing studies of infected hip arthroplasty post-IASHI.

Conclusion: Opinions were mixed, with substantial numbers of surgeons stating that the procedure is not therapeutically helpful, may accelerate arthritis progression, or may increase infections after subsequent total hip arthroplasty. This information provides a systematic collection of expert opinions, as well as a context for forthcoming studies on effectiveness and complications.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 363 - 363
1 Sep 2005
Kaspar S deBeer J
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Introduction and Aims: Intra-articular steroid hip injection (IASHI) for osteoarthritis of the hip has not been well studied. The immunosuppressive nature of steroids may be hypothesised to interfere with asepsis in subsequent total hip arthroplasty (THA). We evaluate the infectious complications and functional outcomes of THA performed in patients who previously received IASHI.

Method: This is a retrospective cohort study of functional outcomes (Harris and Oxford hip scores), and infectious complications in the first year following THA, in patients without (n=40 controls) or with (n=40) a history of ipsilateral IASHI. Functional scores had been compiled in our database, at one tertiary care centre, and infectious complications (wound infection, deep infection, work-up with bone scans, revision surgery) were retrospectively reviewed from hospital records.

Results: The IASHI group had worse post-THA function (p=0.0008 ANOVA for Oxford functional hip scores across time, with mean one-year scores being worse by seven points out of 60). In the IASHI group there were five revision surgeries, four of which were for deep infection of the hip replacement (10%, versus 0% in controls, versus 1.02% in our database of 979 THA primaries, p < 0.001 by Log-Rank testing of Kaplan-Meier survivor-ship analysis). Additionally, each group had two superficial wound infections. Six additional IASHI patients underwent infectious work-ups for ongoing hip problems (compared to one patient worked-up in the control group). The total rate of culture-proven infection (either superficial or deep), or problems leading to negative infectious work-up, was 12/40 (steroid, 30%) versus 3/40 (control, 7.5%, p = 0.010 by Fisher’s Exact test).

Conclusion: IASHI should now be considered as relatively contra-indicated in patients who are (or will become) candidates for THA. IASHI appears to compromise the functional results of subsequent THA, with much higher infection and revision rates. We suggest a multi-centre review of infected THA post-IASHI.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 362 - 362
1 Sep 2005
Kaspar S Kaspar J Winemaker M Colterjohn N Wismer D deBeer J
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Introduction and Aims: Although cortical hypertrophy (CH) in total hip arthroplasty (THA) has been associated with thigh pain and loose femoral stems, its presence has been variable in the literature, and it is an implant-specific phenomenon. The relationship of bony change to clinical outcome has not previously been examined in ceramic THA.

Method: Hardened-bearing surfaces such as ceramics have the potential for altered patterns of force transmission into the femoral stem-bone interface, and as such could lead to altered bone remodelling. We investigate here the incidence and magnitude of CH at the Gruen zones, about the femoral stem of THA utilising ceramic-on-ceramic bearing surfaces without (n=36) or with (n=4) cement, and metal-polyethylene bearing surfaces without (n=40) or with (n=40) cement. Using multifactorial analysis, we examined the relationship of implant alignment, Harris and Oxford hip scores, and bone remodelling parameters.

Results: In this study of 120 patients, the hip scores and x-rays are examined in the first year after total hip arthroplasty (THA), in order to evaluate bone remodelling in relation to clinical outcomes. Ceramics had the highest incidence (25%) and mean size (1.5 mm) of CH, followed by metal-polyethylene (17%, < 1 mm). No cemented implants exhibited CH. There was no significant relationship of bone remodelling to one-year hip scores, although there were significantly reduced pain scores in cases that exhibited endosteal remodelling at one year. CH in ceramic hips appears to be a mechanical phenomenon that is not associated with pain, varus drift, subsidence, or altered clinical outcome. Cement may buffer the stresses seen by the femur, and hence the stimulus for CH appears to be simply mechanical, and is increased with hardened-bearing surfaces.

Conclusion: CH was more common in ceramic THA than metal-polyethylene, but was not associated with increased thigh pain or altered function. CH did not occur when cement was used, and as such we argue for a mechanical origin of the phenomenon, via altered load transmission into the femur through hardened-bearing surfaces.