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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_5 | Pages 138 - 138
1 Mar 2017
Schmaranzer F Haefeli P Hanke M Lerch T Werlen S Tannast M Siebenrock K
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Objectives

Delayed gadolinium enhanced MRI of cartilage (dGEMRIC) is a novel MRI-based technique with intravenous contrast agent that allows an objective quantification of biochemical cartilage properties. It enables a ‘monitoring' of the loss of cartilage glycosaminoglycan content which ultimately leads to osteoarthritis. Data regarding the longitudinal change of cartilage property after joint preserving hip surgery is sparse. We asked (1) if and how the dGEMRIC-index changes in patients undergoing open/arthroscopic treatment of femoroacetabular impingement (FAI) one year postoperatively compared to a control group of patients with non-operative treatment; (2) and if a change correlates with the clinical short term outcome.

Methods

IRB-approved prospective comparative longitudinal study of two groups involving a total of 61 hips in 55 symptomatic patients with FAI. The ‘operative' group consisted of patients that underwent open/arthroscopic treatment of their pathomorphology. The ‘non-operative' group consisted of conservatively treated patients. Groups were comparable for preoperative radiographic arthritis (Tönnis score), preoperative HOOS- and WOMAC-scores and baseline dGEMRIC indices.

All patients eligible for evaluation had preoperative radiographs and dGEMRIC scans at baseline and repeated dGEMRIC scans using the same scanner and protocol. (1) dGEMRIC indices of femoral and acetabular cartilage were assessed separately on the initial and follow-up dGEMRIC scans. Radial images were reformatted from a 3D T1 map for measurements. Regions of interest were placed manually peripherally and centrally within the cartilage based on anatomical landmarks at the 12 ‘hour' position of the clcok-face with the help of radial high-resolution PD-weighted MR images. (2) Patient-reported outcome was evaluated at baseline and at 1 year follow-up: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Hip disability and Osteoarthritis Outcome Score (HOOS). Statistical analysis included Student's t-Tests, Mann-Whitney U-tests and Wilcoxon signed-rank tests (p<0.05).


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 17 - 17
1 Feb 2017
Anwander H Hanke M Steppacher S Werlen S Siebenrock K Tannast M
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Introduction

Magnetic resonance imaging with intraarticular contrast (arthro-MRI) and radial cuts is the gold standard to quantify labral and chondral lesions in the setting of femoroacetabular impingement. To date, no study exists that has evaluated these findings as potential predictors of outcome for the long term follow-up after surgical treatment of FAI.

Objectives

The purpose of this study was to detect potential predictors for failure after surgical hip dislocation for FAI based on specific preoperative arthro-MRI of the hip at a minimum follow-up of 10 years.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 426 - 426
1 Sep 2012
Keck J Kienle K Siebenrock K Steppacher S Werlen S Mamisch TC
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Purpose

The purpose of this retrospective study was to investigate the acetabular morphology of pincer impingement hips in order to better understand damage pattern in these patients. We compared MRI measurements made at different postions from anterior to posterior on the acetbulum in patients with pure pincer type FAI to those made in patients with pure cam-type to collect parameters that may be useful in the diagnosis and classification of pincer impingement.

Material and Methods

From an initial consecutive retrospective population of 1022 patients that underwent MRI with clinical impingement signs 78 hips which were selected with as clear cam (n=57) or pincer (n=21) impingement on plain radiographics. On these MR Imaging was performed with a 1.5-Tesla system. For analysis, a lateral angle of overcoverage on coronal MRI (MR_LCE), the MR extrusion index and the alpha angle (after Nötzli) were used. In addition to these the gamma angle, the acetabular depth and the angle of lateral acetabular overcoverage were described clock-wise on 7 radial slides from anterior to posterior. These were compared between the cam and pincer population using students-t-test. Measurements were obtained by two observers and inter-observer variability was assessed.


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 2 | Pages 171 - 176
1 Mar 2001
Ito K Minka-II M Leunig M Werlen S Ganz R

We have observed damage to the labrum as a result of repetitive acetabular impingement in non-dysplastic hips, in which the femoral neck appears to abut against the acetabular labrum and a non-spherical femoral head to press against the labrum and adjacent cartilage. In both mechanisms anatomical variations of the proximal femur may be a factor. We have measured the orientation of the femoral neck and the offset of the head at various circumferential positions, using MRI data from volunteers with no osteoarthritic changes on standard radiographs. Compared with the control subjects, paired for gender and age, patients showed a significant reduction in mean femoral anteversion and mean head-neck offset on the anterior aspect of the neck. This was consistent with the site of symptomatic impingement in flexion and internal rotation, and with lesions of the adjacent rim. Furthermore, when stratified for gender and age, and compared with the control group, the mean femoral head-neck offset was significantly reduced in the lateral-to-anterior aspect of the neck for young men, and in the anterolateral-to-anterior aspect of the neck for older women. For patients suspected of having impingement of the rim, anatomical variations in the proximal femur should be considered as a possible cause.


The Journal of Bone & Joint Surgery British Volume
Vol. 79-B, Issue 2 | Pages 230 - 234
1 Mar 1997
Leunig M Werlen S Ungersböck A Ito K Ganz R

Since January 1993 we have carried out MR arthrography on 23 patients with clinical symptoms and signs of abnormality of the acetabular labrum. Most of the patients were young adults. Such symptoms are known precursors of osteoarthritis, and therefore early and accurate evaluation is required.

We assessed the value of MR arthrography of the hip as a minimally-invasive diagnostic technique, in a prospective study and compared the findings with those at subsequent operations. All the patients complained of groin pain; 22 had a positive acetabular impingement test and 15 had radiological evidence of hip dysplasia.

In 21 of the patients, MR arthrography suggested either degeneration or a tear of the labrum or both. These findings were confirmed at operation in 18 patients, but there was no abnormality of the labrum in the other three. In two of the patients, MR arthrography erroneously suggested an intact labrum. Both MR arthrography and intraoperative inspection located lesions of the superior labrum most often, and these appeared slightly larger on arthrography than at operation.

We consider that MR arthrography is a promising diagnostic technique for the evaluation of abnormalities of the acetabular labrum.