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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVIII | Pages 12 - 12
1 Jun 2012
Dean F McLeod I
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The benefits of surgical treatments for osteoarthritis (OA) of the knee are well established. There are also advances in non-surgical management techniques that can be used successfully, and these may be particularly suitable for patients with mild to moderate disease, or for those in whom surgery is contra-indicated. Intra-articular viscosupplementation is one such method, and studies have shown that this can give short-term symptomatic relief.

Our study looked at the patient perceived benefits of a course of Hylan G-F 20 (Synvisc¯) by comparing the modified Brief Pain Inventory short form (BPI-sf) scores before treatment and after three months. The BPI-sf is a validated, widely used, self-administered questionnaire that measures both sensory and reactive dimensions of the pain using scales of 0-10 or 0-100%. This study included 12 consecutive patients with OA of the knee treated with a course of three Synvisc¯ injections performed a week apart. The data were treated as non-parametric and therefore Wilcoxon signed rank tests were performed. The data are presented as median (IQR).

The results showed statistically significant (p<0.05), and clinically significant (reduction >1 point) improvements in worst, best, and average pain scores (over the previous 24 hours) three months following treatment compared to those before treatment. Relief obtained from routinely taken analgesia was significantly improved from 30%(12.5-57.5) to 75%(42.5-100) (p=0.009) following treatment. There were significant reductions in the interference of the pain with: general activity from 6(4.25-8.75) to 2.5(0-6.75), (p=0.006); mood from 6(2-8) to 0(0-5), (p=0.004); walking ability from 7.5(4-8.75) to 3.5(0.25-6), (p=0.004); normal work from 5.5(3.5-8) to 1.5(0-5), (p=0.009); relations with other people from 4(2-8) to 0(0-3.5), (p=0.006); sleep from 6(3.25-9.5) to 1.5(0-5.75), (p=0.004); enjoyment of life from 6(2.75-8.5) to 1.5(0-6), (p=0.005). All patients found the treatment acceptable.

We conclude that patients reported significant improvements in pain, physical and emotional functioning, and sleep three months following treatment with this viscosupplementation treatment.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVIII | Pages 2 - 2
1 Jun 2012
Ellapparadja P Husami Y McLeod I
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The posterolateral approach to ankle joint is well suited for ORIF of posterior malleolar fractures. There are no major neurovascular structures endangering this approach other than the sural nerve. The sural nerve is often used as an autologous peripheral nerve graft and provides sensation to the lateral aspect of the foot. Hence every attempt must be made to protect the sural nerve. The aim of this paper is to measure the precise distance of the sural nerve from surrounding soft tissue structures.

This is a retrospective image review study including patients with MRI of their ankle from January 09 - Nov 2010. We indentified 78 MRI scans out of which 64 were deemed eligible for assessment. All measurements were made from Axial T1 slices. Measurements were made from the lateral aspect of the TA to the central of the sural nerve, central of sural nerve to the posterior aspect of the peronei muscles and central of the sural nerve to the posterior aspect of fibula. Data were collected on a Microsoft Excel spreadsheet and the descriptive statistics calculated.

The key findings of the paper is the safety window for the sural nerve from the lateral border of TA is 7mm, 1.3cm and 2cm at 3 cm above ankle joint, at the ankle joint and at the distal tip of fibula respectively. Similarly the safety window for the nerve from the posterior aspect of fibula is 2cm, 1.6cm, 1.6cm at 3cm above ankle, at the ankle joint and the distal tip of fibula respectively.

Our study demonstrates the close relationship of the nerve in relation to tendoachilles, peronei and fibula in terms of exact measurements. The safety margins established in this study should enable the surgeon in preventing endangerment of the sural nerve encountered in this approach.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 64 - 64
1 Jan 2011
Cheng KCK St Mart J Robertson H Leanord A McLeod I
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Eradication of bacteria in forefoot surgery in necessary to prevent post-operative infections. Currently a lack of consensus exists on the optimum solution and preparation methods needed to achieve this. We compared the effect of povidine-iodine and chlorhexidine gluconate on lowering bacterial load and if any additional benefits are gained by pre-treatment with the use of a bristled brush.

Fifty consecutive patients undergoing forefoot surgery were recruited into the study and randomised to receive one of two surgical skin preparations (Povidine-iodine 1% with isopropyl alcohol 23% or Chlorhexi-dine gluconate 0.5% with isopropyl alcohol 70%). In addition to the skin preparation of the foot with the randomised solution the other foot was also scrubbed with a sterile surgical bristled brush for a standardised period (3 minutes) and then painted again. Swabs were taken from three sites and analysed via qualitative and quantitative analysis.

All four methods significantly decreased (p < 0.001), in all three sites, the number of colony forming units. Using two-way analysis of variance no significant interaction was observed between site of swab and method of preparation (p =0.970). This confirms that no preparation method was more superior in reducing the number of CFUs at any site than the others.

We suggest that either povidone –iodine with no more that 23% isopropyl alcohol or chlorhexidine gluconate with 70% isopropyl alcohol be used for surgical preparation in forefoot surgery. No additional benefit in reduction in bacterial load is gained by scrubbing the foot prior to painting with bristles.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 245 - 245
1 Mar 2010
Cheng K Robertson H Leanord A St-Mart JP Mcleod I
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Aim: To assess the effectiveness of povidone-iodine alcoholic tincture and the alcoholic chlorhexidine gluconate solution in the eradication of bacteria in forefoot surgery, and to assess any added benefits with the use of surgical bristles.

Methods: Fifty consecutive patients were prospectively enrolled into the study and randomised to receive one of two surgical skin preparations.

Results: The use of povidone-iodine with prior surgical scrubbing had a better eradication rate compared to povidone-iodine alone in the interdigital web-spaces. Prior surgical scrubbing with both solutions had a better eradication rate for the skin over the 1st metatarso-phalangeal joints. But neither solution with or without the use of surgical scrubbing was superior at eradicating organisms from the medial hallucal fold. However none of these results were statistically significant. None of the patients developed any post-operative wound infection.

Conclusions: Our results did not show any statistically significant advantage with either solution nor was there any apparent advantage with the use of the surgical scrub prior to the skin preparation. The authors believe that eradication of bacteria in forefoot surgery is dependant on a meticulous and methodical skin preparation technique and less so on the solution used and method of application.