Distraction osteogenesis (DO) mobilises bone regenerative potential and avoids the complications of other treatments such as bone graft. The major disadvantage of DO is the length of time required for bone consolidation. Mesenchymal stem cells (MSCs) have been used to promote bone formation with some good results. We hereby review the published literature on the use of MSCs in promoting bone consolidation during DO.Objectives
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Multifocal osteonecrosis (ON) was defined by Mont et al. as a disease involving three or more anatomic sites. Few papers have been published on the Chinese experience. The purpose of this study was to characterize the experience with multifocal ON in order to make an earlier diagnosis for more patients with this disorder. From 2003 to 2008, thirty nine patients with multifocal ON were identified in our clinical practice. Among them, thirty seven patients were post-SARS rehabilitating patients and two patients were found in clinic. All patients had a history of high dose corticosteroid therapy. The diagnosis was done by magnetic resonance imaging (MRI) and radiographs. All patients were treated by drug or other joint-salvaging procedure. Three patients had bilateral total hip arthroplasties.Introduction
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