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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_II | Pages 55 - 55
1 Feb 2012
Vioreanu M O'Brien D Dudeney S Hurson B O'Rourke K Kelly E Quinlan W
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The aim of operative treatment for ankle fractures is to allow early movement after internal fixation. The hypothesis of this study was that early mobilisation facilitated by a removable cast after internal fixation of ankle fractures would improve functional recovery of patients compared with that after conventional immobilisation in a cast.

Sixty-two patients between the age of seventeen and sixty-five with ankle fractures that required operative treatment were randomly allocated to two groups: immobilisation in a non weight bearing below knee cast for six weeks or early movement in a removable cast (at two weeks after removal of sutures) for the following four weeks. The follow-up examinations which consisted of subjective (clinical, Olerud-Molander score, AOFAS score, SF 36) and objective (swelling measurement, x-ray) evaluations were performed at two, six, nine, twelve and twenty four weeks post-operatively. Time of return to work was recorded.

There were two post-operative complications in the group treated with immobilisation in cast; two patients had deep vein thrombosis (DVT). There was one superficial wound infection treated with oral antibiotics and two deep wound infections requiring removal of metal in the group treated with early movement in a removable cast. Patients in group two (early movement) had higher functional scores at nine and twelve weeks follow-up. They also returned to work earlier (63.7 days) compared with the ones treated in cast (94.9 days). There was no statistical difference in Quality of Life (SF-36 Questionnaire) at six months between the two groups.

Early movement with the use of removable cast after removal of sutures in operated ankle fractures decreases swelling, prevents calf muscle wasting, improves functional outcome and facilitates early return to work of patients. Our findings support the use of a removable cast and early exercises in selected, compliant patients after surgery of the ankle.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_II | Pages 106 - 106
1 Feb 2012
Vioreanu M Robertson I O'Toole G Connolly P O'Byrne J
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Radiographic follow-up of traumatic spondylolisthesis of the axis is well documented in the literature. However, there is a paucity of studies regarding the long-term functional outcome of this type of injury.

To study the population, treatment and outcome following traumatic spondylolisthesis of the axis, we reviewed 36 consecutive patients presenting to our institution, a tertiary referral spinal trauma centre, over a 6-year period. We assessed: (a) the mechanism of injury, (b) the mode of treatment, (c) the radiographic classification using the Levine and Edwards system and (d) functional outcome using the Cervical Spine Outcomes Questionnaire (CSOQ) by BenDebba.

Of the 36 patients presenting there were 24 males and 12 females with a mean age of 46 (range18-82) years. The commonest mechanism of injury was road traffic accidents. There were 14 Type-I, 11 Type-II and 1 Type-IIA fractures. Twenty-seven patients were treated with halo vest immobilisation and nine were immobilised in a Minerva jacket. Four patients were converted from halo to Minerva because of pin failure. The mean duration of hospital stay was 10 (range 3-30) days. All fractures demonstrated radiographic union at a mean of 12 (range 10-16) weeks. There were no neurological complications. Upon review, all patients, whether Type-I or Type-II demonstrated low CSOQ scores approaching their pre-morbid status. However, Type-II fractures scored higher in 3 functional outcome categories when compared to Type-I fractures.

This unique study of an uncommon fracture shows for the first time a difference in the functional outcome scores of Type-II fractures of the axis when compared to Type-I fractures at a mean follow-up of 3 years and 10 months.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 612 - 612
1 Oct 2010
McHugh G Devitt B Moyna N O’Byrne J Vioreanu M Walls R
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Introduction: Quadriceps femoris (QF) atrophy has been associated with the development of knee OA and is a major cause of functional limitations in affected individuals. TKA reliably reduces pain but improvements in function are less predictable and deficits may persist for up to 2 years post-operatively. Patients undergoing elective surgery are routinely optimized medically but we hypothesized that pre-operative strength and fitness improvements would also enhance outcome.

Objectives: To determine the effect of a 6 week lower limb strengthening programme on post-operative QF strength and CSA, pain and functional scores.

To determine changes in Myosin Heavy Chain (MHC) isoform, hypertrophy marker IGF-1 and atrophy markers MuRF-1 and MAFbx.

Methods: 20 volunteers currently awaiting TKA were randomly assigned to a control [C] or intervention [I] group. [I] completed a 6 week home based, supervised exercise programme. Post-operatively all patients completed a standard inpatient physiotherapy routine.

Assessments were completed at baseline (T=0), T=6 weeks (just prior to operation) and 3 months post-operatively (T=18 weeks). Assessments included isokinetic dynamometry; MRI QF CSA and American Knee Society scores. A percutaneous muscle biopsy of the vastus lateralis muscle was also performed at T=0 and T=6 under local anaesthesia.

Results: At baseline there were no significant differences in parameters between groups. At T=18, [I] showed an 86% difference in QF peak torque above controls (P=0.003). CSA also improved by 6% versus a drop of 2.5% in [C] (P=0.041). Both groups showed improvements in Knee society function scores but [I] improved by 13 points more than [C] (P=0.044).

MHC IIa mRNA expression increased by 40% whilst IIx decreased by 60% representing a shift to a less fatigable fibre type (P=0.05 and 0.028 respectively). IGF-1, MuRF-1 and MAFbx mRNA levels did not change significantly in either group.

Conclusion: To our knowledge we have documented for the first time post-operative benefits by using a pre-operative training programme in TKA. This was manifest by continued rise in quadriceps peak torque, CSA and improved Knee society functional scores. We have also demonstrated the preservation of muscle plasticity in knee OA and suggest that factors other than known hypertrophy and atrophy pathways may be responsible.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 280 - 280
1 May 2006
Vioreanu M O’Briain D Dudeney S Hurson B O’Rourke K Kelly E Quinlan W
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Background: The aim of operative treatment for ankle fractures is to allow early movement after internal fixation. The hypothesis of this study was that early mobilisation facilitated by a removable cast after internal fixation of ankle fractures would improve functional recovery of patients compared with that after conventional immobilisation in a cast.

Material and Methods: Sixty two patients between the age of seventeen and sixty five with ankle fractures that required operative treatment were randomly allocated to two groups : immobilisation in a non weight bearing below knee cast for six weeks or early movement in a removable cast ( at two weeks after removal of sutures ) for the following four weeks. The follow up examinations which consisted of subjective (clinical, Olerud-Molander score, AOFAS score, SF 36 ) and objective ( swelling measurement, x-ray ) evaluations were performed at two, six, nine, twelve and twenty four weeks postoperatively. Time of return to work was recorded.

Results: There were no postoperative complications in the group treated with immobilisation in cast. There was one superficial wound infection treated with oral antibiotics in a patient with a previous dermatological condition around the fractured ankle in the group treated with early movement in a removable cast. Patients in group two ( early movement ) had higher functional scores at nine and twelve weeks follow up but not of statistical significance. They also return to work earlier ( 55.5 days ) compared with the ones treated in cast ( 98.7 days ). Patients treated in removable cast had higher mean SF-36 scores, but this difference was significant only for two of the eight aspects investigated.

Conclusions: Early movement with the use of removable cast after removal of sutures in operated ankle fractures decrease swelling, prevent calf muscle wasting, improve functional outcome and facilitate early return to work of patients. Our findings support the use of a removable cast and early exercises in selected, compliant patients after surgery of the ankle.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 281 - 281
1 May 2006
Vioreanu M Brophy S Kearns S Kelly E Hurson B O’Rourke S Quinlan W
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Introduction: The optimal management of ankle fractures in the elderly is controversial, with wide variation in the complication rates reported in the literature. Achieving a satisfactory outcome is essential as reduced mobility exacerbates pre-existing morbidity and diminishes the likelihood of independent living. However, in elderly patients surgery carries increased risks due to osteoporosis, poor skin condition and decreased vascularity.

Methods: We performed a retrospective review of outcome and complications in patients over 70 years of age with ankle fractures. Patients were admitted for manipulation under anaesthetic and application of cast (MUA) or open reduction and internal fixation (ORIF). Data were retrieved from medical and nursing notes relating to pre-operative functioning, type of injury, operative procedure and outcome. All X-rays were also reviewed to confirm fracture grade and union.

Results: A total of 134 patients over the age of 70 were admitted for management of ankle fractures during January 1995 and December 2003 and 117 of these were included in the study. 84 were operatively treated for ankle fractures and a further 27 patients underwent MUA. The mean age in both groups was 76 and there was a female predominance in both groups (89% in MUA, 79% in ORIF). 14.8% of the conservatively managed group were nursing home residents compared to 2.4% of the operatively treated group. The groups were similar with respect to ASA grade and co-morbidities. The median length of stay was shorter for the conservatively managed group (4 vs. 6 days). 7.5% of the MUA group required a second intervention compared to 4.5% of the operatively managed group. There were two below knee amputations in the operatively managed group, both related to open fractures, and one arthrodesis in each group. There were three wound complications in the operatively managed group. The rate of postoperative medical complications was the same in both cohorts. 7.4% of patients treated with MUA and 1.1% of patients treated operatively had reduced mobility at final follow-up.

Conclusion: The decision-making process for treatment of ankle fractures in the geriatric population is challenging. We observed significantly better functional results in the ORIF group than the MUA group. These results indicate that open reduction and internal fixation of ankle fractures in geriatric patients is efficacious and safe in selected patients


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 123 - 123
1 Feb 2004
Vioreanu M Quinlan J O’Byrne J
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Introduction: Fractures of the sternum result from a direct blow or from an indirect mechanism with hyperflexion of the spine. The association between spinal injury and sternal fractures has been reported but is commonly overlooked and underestimated.

Aims: Our aim was to study the clinical and radiological effects of an attendant sternal fracture on vertebral fractures. Berg first described the extra stability afforded to the thoracic spine by the sternal-rib complex and the adverse effects of damage to this “4th column” apropos of 2 cases.

Materials and Methods: None patients were admitted to our unit from October 1996 to August 2001 suffering from vertebral fractures and concomitant sternal fractures. The clinical notes and plain film radiographs of these patients were studied.

Results: The average age of the 9 patients (5 males and 4 females) was 33 years (range 21–73). Seven had been involved in road traffic accidents and 2 had fallen from a height. Four patients had injuries to their cervical spine, 4 to their thoracic spine and one had a lumbar spine fracture. In terms of neurological compromise, only one of the cervical groups had a neurological deficit compared to all 4 in the thoracic group (2 complete and 2 incomplete). The patient with the lumbar spine fracture suffered incomplete neurological compromise. All 6 of the patients with neurological compromise underwent surgical management. The other 3 patients were treated conservatively.

Conclusion: It has been traditionally accepted that the sternum is injured only in association with upper thoracic spine. Our findings suggest that spinal injury at lower thoracic, upper lumbar or cervical level may also be associated with sternal injuries. However, the relative severity of the vertebral injury and neurological compromise in the thoracic spine subgroup offers clear support of Berg’s “4th column” theory of thoracic spine fractures when compared to fractures of the cervical or lumbar spine with sternal injuries.