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Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_11 | Pages 95 - 95
1 Jul 2014
ALTERATIONS IN THE PROPERTIES OF RABBIT ARTICULAR CARTILAGE AND UNDERLYING BONE AT FOUR WEEKS AFTER ANTERIOR CRUCIATE LIGAMENT TRANSECTION
Florea C Malo M Rautiainen J Mäkelä J Nieminen M Jurvelin J Davidescu A Korhonen R
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Summary

In a rabbit model of early osteoarthritis, structural changes in femoral condyle cartilage were severer in the lateral compartment and preceded alterations in the underlying bone. In the medial compartment, altered bone properties occurred together with structural changes in cartilage.

Introduction

Early osteoarthritic changes in cartilage have been previously studied through anterior cruciate ligament transection (ACLT) in rabbits. However, parallel changes in the structure of subchondral and trabecular bone at 4 weeks after ACLT are not known.