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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_16 | Pages 78 - 78
19 Aug 2024
Holland CT Leal J Easley ME Nunley JA Ryan SP Bolognesi MP Wellman SS Jiranek WA
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This study evaluates patient reported outcome measurement information system (PROMIS) scores after total hip arthroplasty (THA) and total ankle arthroplasty (TAA) in matched cohorts, while simultaneously evaluating implant survivorship and 90-day hospital utilization. It is hypothesized that while both procedures would yield similar PROMIS score improvements, THA would demonstrate superior mid-term implant survivorship.

Primary THA and TAA patients from 2015–2022 with minimum one-year follow-up were retrospectively reviewed. After applying exclusion criteria, 2,092 THAs and 478 TAAs were included for analysis. Demographics, pre- and post-operative patient reported outcome measures (PROMs), revision surgeries, ED visits, and re-admissions were collected. THA and TAA patients were then propensity score matched at 2:1 ratio for age, sex, race, BMI, ASA, and comorbidities, resulting in a final cohort of 844 THAs and 455 TAAs for comparison.

There were similar pre-operative PROMIS Pain Interference (PI) scores between THA and TAA, with both showing improvement at six weeks. However, THA patients exhibited lower PI scores at one year (53.0 versus 54.0; p=0.009). Pre-operative PROMIS Physical Function (PF) was worse in THA patients but showed greater improvement compared to TAA patients at both six weeks (p<0.001) and one year (p<0.001). Pre-operative PROMIS depression scores were similar and improved similarly in both groups. Joint-specific PROMs (HOOS for THA and FAAM for TAA) improved in both cohorts. THA demonstrated superior survivorship free of all-cause revision at five years compared to TAA (95% versus 77%; p<0.0001).

Patients undergoing THA or TAA experienced significant improvements in their general and joint-specific PROMs post-operatively. However, patients undergoing THA demonstrated higher PROMIS PI and PF scores at one-year when compared to TAA, as well as improved survivorship. Generic PRO instruments enable comparison of medical treatments in different anatomic sites to the patients overall health.


The Bone & Joint Journal
Vol. 106-B, Issue 6 | Pages 555 - 564
1 Jun 2024
Leal J Holland CT Cochrane NH Seyler TM Jiranek WA Wellman SS Bolognesi MP Ryan SP

Aims

This study aims to assess the relationship between history of pseudotumour formation secondary to metal-on-metal (MoM) implants and periprosthetic joint infection (PJI) rate, as well as establish ESR and CRP thresholds that are suggestive of infection in these patients. We hypothesized that patients with a pseudotumour were at increased risk of infection.

Methods

A total of 1,171 total hip arthroplasty (THA) patients with MoM articulations from August 2000 to March 2014 were retrospectively identified. Of those, 328 patients underwent metal artefact reduction sequence MRI and had minimum two years’ clinical follow-up, and met our inclusion criteria. Data collected included demographic details, surgical indication, laterality, implants used, history of pseudotumour, and their corresponding preoperative ESR (mm/hr) and CRP (mg/dl) levels. Multivariate logistic regression modelling was used to evaluate PJI and history of pseudotumour, and receiver operating characteristic curves were created to assess the diagnostic capabilities of ESR and CRP to determine the presence of infection in patients undergoing revision surgery.


The Bone & Joint Journal
Vol. 106-B, Issue 1 | Pages 38 - 45
1 Jan 2024
Leal J Mirza B Davies L Fletcher H Stokes J Cook JA Price A Beard DJ

Aims

The aim of this study was to estimate the incremental use of resources, costs, and quality of life outcomes associated with surgical reconstruction compared to rehabilitation for long-standing anterior cruciate ligament (ACL) injury in the NHS, and to estimate its cost-effectiveness.

Methods

A total of 316 patients were recruited and randomly assigned to either surgical reconstruction or rehabilitation (physiotherapy but with subsequent reconstruction permitted if instability persisted after treatment). Healthcare resource use and health-related quality of life data (EuroQol five-dimension five-level health questionnaire) were collected in the trial at six, 12, and 18 months using self-reported questionnaires and medical records. Using intention-to-treat analysis, differences in costs, and quality-adjusted life years (QALYs) between treatment arms were estimated adjusting for baseline differences and following multiple imputation of missing data. The incremental cost-effectiveness ratio (ICER) was estimated as the difference in costs divided by the difference in QALYs between reconstruction and rehabilitation.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 6 - 6
1 Jul 2022
Hamilton T Knight R Stokes J Rombach I Cooper C Davies L Dutton S Barker K Cook J Lamb S Murray D Poulton L Wang A Strickland L Duren BV Leal J Beard D Pandit H
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Abstract

Introduction

This multi-centre randomised controlled trial evaluated the clinical and cost effectiveness of liposomal bupivacaine for pain and recovery following knee replacement.

Methodology

533patients undergoing primary knee replacement were randomised to receive either liposomal bupivacaine (266mg) plus bupivacaine hydrochloride (100mg) or control (bupivacaine hydrochloride 100mg), administered at the surgical site. The co-primary outcomes were pain visual analogue score (VAS) area under the curve (AUC) 6 to 72hours and the Quality of Recovery 40 (QoR-40) score at 72hours.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 77 - 77
1 Mar 2006
Ribas M Vilarrubias J Ginebreda I Silberberg J Leal J
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Introduction: Femoroacetabular Impingement had been until now an unknown pathology. It causes pain in the movements of flexion-adduction-internal rotation, due to a bump effect between the head-neck surface of the femur and the anterior acetabular rim.

Material and Method: We analysed our 14 first patients, 3 operated bilaterally with 1 year F.U.. In bilateral cases, the time between both operations ranged from 5 to 8 weeks. Mean Age: 36 years (27 to 48), all sports active patients.. The technique that we used was through our modified Hueter approach . The superoanterior rim of the acetabulum was excised as well as the deformity at the femoral side that causes a less femoral neck-offset. For that purpose we used special maxilofacial-reamers instead of chisels. In this way we avoid any bleeding from the femoral neck. With this technique we avoid a Trochanter osteotomy, as performed by other authors (Ganz, Trousdale) .

Results: Pain relief was obtained 4 weeks after surgery in 13 from 14 patients. Mean hospitalization time was 2,6 days (2 to 5). Improvement in ROM was significative (p= 0,006): from −17 mean internal rotation (−14 to −28) at 80 flexion to +23 mean one month postop internal rotation (14 to 32).There was a significant improvement of hip score according to Merle d’Aubigne evaluation (p=0,017): 13,8 points preop (13 to 15) to 16,9 at F.U. (16–18). Neither Trendelemburg nor osteonecrosis was observed in any patient, as possible complications related to the approach. Mean time of rehabilitation was 3,8 weeks ( 3 to 5). All patients returned to their respective sports activities

Discussion: The Modified Femoroacetabular Osteoplasty allows rapid improvement of the normal hip motion , relatively short rehabilitation time and sports resumption as well. However midterm new osteoarthritic changes had to be assessed, although clinical and functional improvement has been evident. This surgical procedure makes us think about other alternatives to hip endoprosthesis in young adults.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 99 - 99
1 Mar 2006
Ribas M Vilarrubias J Silberberg J Leal J Ginebreda I
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Introduction: knee revision in absence of Extensor Mechanism has been always a challenging problem in Orthopaedics. Many authors are in favour to abandone any endoprosthetic substitution in front of such a situation.

We think osteotendinous allografts, in this particular case whole Extensor Mechanism allografts, could play an essential role before any Knee Arthrodesis.

Material and Method: From 1999 up to 2004 11 patients (4 male, 7 female) (mean age 72, range 68 to 86) underwent to a whole Extensor Mechanism allografting procedure. Mean follow up was 2.7 years (1 to 5 years).

In the first four cases a whole Extensor Mechanism allograft was implanted, while the next seven cases the allograft was reinforced by means of a Leeds-Keio Dacron band.

Results: There was no infections in this serie. The mean obtained R.O.M. in the first three months was – 5 of active extension (range 0 to −15) and 95 active flexion (range 80 – 110). However 3 from the 4 former operated cases had a progressive loss of active extension up to −25 (range −20 to −35) at 18 months, that did not increase after this period. Ultrasonic exams showed a lengthening of the patellar tendon in these cases. None of these 3 patients wished to undergo to a patellar tendon reinforcement.

On the other hand those later cases, where patellar tendon was reinforced did not show any change over the time (at 18 months mean active extension was maintained to −5 (range 0 to 15)

Conclusions: Extensor mechanism allografts are very useful in difficult knee revisions with absence of extensor mechanism, so that knee arthrodesis is not the method of choice for these patients. However augmentation of patellar tendon is necessary to maintain with the years an active extension.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_I | Pages 84 - 84
1 Mar 2005
Ribas M Leal J Vilarrubias JM
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Introduction: Chiari osteotomy with capsuloplasty is an acetabulum-widening osteotomy which makes it possible to substantially correct dysplastic hips. This paper presents an overview of the results obtained after 25 years.

Materials and methods: Between 1983 and 2002, 127 Chiari osteotomies were carried out. 103 were revised (59 women, 40 men , 4 bilateral). Mean follow up: 11.2 years (range: 1 to 20 years). The endpoints were: operative time, VCA angles, acetabular inclination, pre-post-follow up CE angle, Merle d’Aubigne score, preop and postop Ahlbach score.

Results: Operative time: 1h 42′ (range: 57′ – 3h 10′). Ahlbach I – 26, II – 59, III – 18, IV – 0. Associated operations: Femoral osteotomy 77, varus-derotation osteotomy 36, Reconversion 31, Trochanteric retensioning. M 69. Angles measurement: preop: CE 5° (−34°−25°), VCA 18° (7°–26°), Tönnis 56° (43°–61°). Postop: CE 34° (10°–55°), VCA 31° (26°–39°), Tönnis 40° (38°–44°). Mean increase in acetabular inclination:16°. Merle d’Aubigné: preop 14.3(7–17), Follow-up 16.2(12–18). Excellent-good results 89(86.4%), Fair-poor results 14(14.6%) 2 went on to THA; Mean osteotomy displacement 26 mms (18–39). Invariability Ahlbach changes: If preop I 24/26(92.3%), if preop II 42/59(71.2%), if preop III 5 /18 (27.7%). Survival rate: 81.76% after 10 years.

Discussion and conclusions: Long term results seem satisfactory, with a survival rate of 81.76% after 10 years. This is a technique of choice in dysplasias with a new cup and in non-congruent hips, generally associated to a femoral osteotomy (77/103). It is crucial to perform the preop planning using Pawels test.