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Bone & Joint Research
Vol. 7, Issue 7 | Pages 485 - 493
1 Jul 2018
Numata Y Kaneuji A Kerboull L Takahashi E Ichiseki T Fukui K Tsujioka J Kawahara N

Objective

Cement thickness of at least 2 mm is generally associated with more favorable results for the femoral component in cemented hip arthroplasty. However, French-designed stems have shown favorable outcomes even with thin cement mantle. The biomechanical behaviors of a French stem, Charnley-Marcel-Kerboull (CMK) and cement were researched in this study.

Methods

Six polished CMK stems were implanted into a composite femur, and one million times dynamic loading tests were performed. Stem subsidence and the compressive force at the bone-cement interface were measured. Tantalum ball (ball) migration in the cement was analyzed by micro CT


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 56 - 56
1 Jan 2016
Moussa H Scemama C Kerboull L
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Introduction

Excellent long-term survival rates associated with the absence of stem subsidence have been achieved with total hip arthroplasty (THA) using femoral components cemented line-to-line (“French Paradox”). Recently, short stems have been introduced in order to preserve diaphyseal bone and to accommodate to minimal invasive THA and a variety of clinical situations. The aim of the current study was to quantify the rotational and tilting stability of a Kerboull stem of varying length after line-to-line cementation using a validated in-vitro model.

Materials & methods

The femoral component made of M30NW stainless steel was derived from the original Kerboull stem. It had a double taper, a highly polished surface, and a quadrangular cross-section. Four stem lengths were designed from the original length with a distal reduction of 6, 12, 17 and 22%, whereas the proximal body geometry of the implant remained unaffected. For each stem length, five specimens were implanted into a non-canal synthetic femoral model. The femoral preparation was performed in order to obtain rotational and tilting stability of the stem prior to the line-to-line cementation. Spatial micro-motions of the specimens were investigated using a validated rotational measuring set-up. In addition, in a second separate step, the specimens were exposed to a ventro-dorsal moment to mimic varus-valgus moment. Statistical analysis was performed using ANOVA with Fisher PLSD.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 85 - 85
1 Jun 2012
Masri FE Kerboull L Kerboull M Courpied JP Hamadouche M
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Introduction

The purpose of this study was to evaluate the in vivo migration patterns of a polished femoral component cemented line-to-line using EBRA –FCA.

Methods

The series included 164 primary consecutive THAs performed in 155 patients with a mean age of 63.8 years. A single prosthesis was used combining an all-polyethylene socket and a 22.2 mm femoral head. The monoblock double tapered femoral component made of 316-L stainless steel had a highly polished surface (Ra 0.04 micron) and a quadrangular section (Kerboull(r) MKIII, Stryker). The femoral preparation included removal of diaphyseal cancellous bone to obtain primary rotational stability of the stem prior to the line-to-line cementation. Stem subsidence was evaluated using EBRA-FCA software which accuracy is better than ± 1.5 mm (95% percentile), with a specificity of 100% and a sensitivity of 78% for detection of migration of more than 1.0 mm, using RSA as the gold standard.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 12 - 12
1 Jun 2012
Bercovy M Kerboull L
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We present a new technique for TKA implantation which utilizes patient-specific femoral and tibial positioning guides developed from MRI to offer an individualized approach to total knee replacement.

This is a prospective non controlled study which aims to analyse the precision of this technique, its advantages and inconvenients in comparison with the conventional instrumented technique.

Material

The MRI provides a consistent three-dimensional data set of the patient's anatomy which allows for 3D axis identification.

The ideal position and sizing is performed by the surgeon on this 3D model and the patient specific guides are manufactured in advance in order to reproduce the bone cuts corresponding to this positioning and implant size. There are no intramedullary nor extramedullary instruments during the surgery.

Method

We compared 20 patients operated with this technique with 20 patients operated with the conventional technique.

The hypothesis was a difference < 2° between the 2 techniques

The measured parameters were:

HKS, HKA, tibial slope, femoral rotation on CT

Duration, bleeding, pain on VAS and morphine consumption, active flexion, KSS, Oxford score, recovery of independant walking and delay of return to home.

Both groups were identical for gender, age, BMI, etiology, comorbidities, pain and rehabilitation protocols.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 300 - 300
1 May 2010
Hamadouche M Baqué F Lefevre N Kerboull L Kerboull M Courpied J
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Introduction: The purpose of this study was to report on the minimal 10-year followup results of a prospective randomized and a historical series of low friction cemented hip arthroplasties according to the surface finish of the femoral implant.

Patients and Methods: The prospective randomized series included 284 patients (310 hips) with a mean age of 64.1 years. Among these 310 hips, the femoral component had a highly polished surface (Ra = 0.04 micron, MKIII, Stryker) in 165 hips, and a matte surface finish (Ra = 1.7 microns, CMK3, Vector Orthopedique) in the remaining 145 hips. The historical series that was operated by the sames surgeons according to the same surgical technique included 111 patients (123 hips) with a satin finish femoral component (Ra = 0.9 micron, CMK2, Sanortho). Clinical results were rated according to the Merle d’Aubigne hip score. Radiologic analysis was performed according to the criteria of Barrack et al. for the definition of loosening. Moreover, a survival analysis according to the actuarial method was conducted.

Results: At the minimum 10-year follow-up evaluation, 43 patients (48 hips) were lost to follow-up (0.3 to 8.7 years), 80 patients (83 hips) were deceased (0.1 to 13.6 years), 26 patients had revision of either or both components (0.9 to 15.9 years), and 246 patients (276 hips) were alive and had not been revised after a mean 12.3 ± 1.9 years (10 to 16 years). Radiologic loosening of the femoral component, including revision, occured in one, four, and 15 hips for the polished, stain, and matte groups, respectively. The survival rate at 13 years of the femoral component, using loosening as the end point, was 97.3 ± 2.6% (95% CI, 92.2 to 100%), 97.1 ± 2.1% (95% CI, 93 to 100%), and 78.9 ± 5.8% (95% CI, 67.6 to 90.3%) for polished, satin, and matte stems, respectively.

Discussion: This study demonstrated that cement fixation of a femoral component was more reliable in the long term with a polished or satin surface finish. Based upon our results and the review of the literature, we recommend abondoning the use of cemented stems with a surface roughness greater than 1 micron.


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 3 | Pages 342 - 348
1 Mar 2010
El Masri F Kerboull L Kerboull M Courpied JP Hamadouche M

We have evaluated the in vivo migration patterns of 164 primary consecutive Charnley-Kerboull total hip replacements which were undertaken in 155 patients. The femoral preparation included removal of diaphyseal cancellous bone to obtain primary rotational stability of the stem before line-to-line cementing. We used the Ein Bild Roentgen Analyse femoral component method to assess the subsidence of the femoral component.

At a mean of 17.3 years (15.1 to 18.3) 73 patients were still alive and had not been revised, eight had been revised, 66 had died and eight had been lost to follow-up. The mean subsidence of the entire series was 0.63 mm (0.0 to 1.94). When using a 1.5 mm threshold, only four stems were considered to have subsided. Our study showed that, in most cases, a highly polished double-tapered stem cemented line-to-line does not subside at least up to 18 years after implantation.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 3 | Pages 304 - 309
1 Mar 2009
Kerboull L Hamadouche M Kerboull M

We describe 129 consecutive revision total hip replacements using a Charnley-Kerboull femoral component of standard length with impaction allografting. The mean follow-up was 8.2 years (2 to 16). Additionally, extramedullary reinforcement was performed using struts of cortical allograft in 49 hips and cerclage wires in 30.

There was one intra-operative fracture of the femur but none later. Two femoral components subsided by 5 mm and 8 mm respectively, and were considered to be radiological failures. No further revision of a femoral component was required. The rate of survival of the femoral component at nine years, using radiological failure as the endpoint, was 98%. Our study showed that impaction grafting in association with a Charnley-Kerboull femoral component has a low rate of subsidence. Reconstruction of deficiencies of distal bone with struts of cortical allograft appeared to be an efficient way of preventing postoperative femoral fracture for up to 16 years.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 124 - 125
1 Apr 2005
Kerboull L Hamadouche M Courpied J Kerboull M
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Purpose: The purpose of this retrospective study was to evaluate the clinical and radiological results of Charnley-Keroboull total hip arthroplasty performed in patients aged less than 50 years. We searched for factors which might affect wear and sustained fixation.

Material and methods: Among the 2,804 arthroplasties performed in patients aged less than 50 years between 1975 and 1995, we selected randomly 287 (10% of the annual operations). These prostheses were implanted in 222 patients (144 women and 78 men), mean age 40.1±8 years (15–50). All of the arthroplasties were inserted via a transtrochanteric approach. Charnley-Kerboull implants were cemented in all patients using a metal polyethylene bearing. Functional outcome was assessed with the Postel-Merle-d’Aubigné score. Cup wear was measured with the Chevrot technique. The actuarial method was used to calculate prosthesis survival.

Results: At last follow-up, 155 patients (210 hips) were living and had not had a revision procedure at mean 16.1±4.6 years, 23 patients (25 hips) required revision of the acetabular or femoral element, ten patients (10 hips) had died, and 34 patients (42 hips) were lost to follow-up. The mean preoperative functional score was 9.6±2.5 (9–15) versus 17.2±0.8 (9–18) at last follow-up (Wilcoxon rank test p< 0.001). For the acetabular element, there was certain loosening in 15 hips and possible loosening in 24. For the femoral element, loosening was certain for 12 implants and possible for four. Twentyfive hips required revision, including 17 for aseptic loosening. Mean wear was 0.12±0.21 mm (0–2.23). Among the 287 hips, 196 had wear measured at less than 0.1 mm/yr (mean 0.02 mm/yr). Mean overall implant survival, defining revision as failure, was 85.4±5.0% at twenty years (95%CI 78.4–92.4). Among the factors tested, only abnormally rapid wear (> 0.1 mm/yr) was predictive of failure.

Discussion: The results of this series allow us to conclude that total hip arthroplasty using a Charnley-Kerboull implant remains the best solution for young patients in terms of implant survival.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 138 - 139
1 Apr 2005
Hamadouche M Lefevre N Kerboull L Kerboull M Courpied J
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Purpose: Certain authors have indicated that the primum movens of loosening of cemented femoral stems is related to the decohesion of the cement implant interface. Under such conditions, improvement in this interface was attempted with the development of a rough surface for the femoral piece. The purpose of this retrospective analysis was to evaluate results a minimum ten years follow-up in a consecutive series of total hip arthroplasties comparing types of femoral implant surfaces.

Material and methods: Between January 1988 and December 1989, 311 THA were implanted in 286 patients aged 63.6±11.8 years (26–91). All implantations were performed via the transtrochanteric approach by two senior surgeons. Two types of femoral implant were used: 166 non-polished pieces with a round section Ra = 3 mm (CMK3, Vector Orthopédique) and 145 polished pieces with a quadrangular section Ra = 0.4 mm (MKIII, Stryker Howmedica). The preoperative data were comparable for the two groups. Functional results were assessed with the Postel Merle d’Aubigné score (PMA). Actuarial survival curves were plotted.

Results: At minimum ten years follow-up, 187 patients (204 hips) were living and had not required revision at mean follow-up of 11.7±2.5 years (10–14), 15 patients (15 hips) had revision of the acetabular and/or femoral element, 54 patients (58 hips) had died, and 30 patients (34 hips) were lost to follow-up. The mean preoperative function score was 11.2±2.5 (4–16) versus 17.5±0.5 (10–18) at last follow-up (Wilcoxon rank test, p< 0.001). Cumulative survival at 13 years, taking radiographic loosening of the femoral piece as the endpoint, was 78.9±5.8% (95%CI 67.6–90.3%) for unpolished implants versus 97.3±2.6 (95%CI 92.2–100) for polished implants. The difference was significantly different (p< 0.001).

Discussion: The results of this analysis indicate that radiographic survival of unpolished cemented femoral pieces is significant inferior compared with polished pieces. The increased adherence of the femoral cement is probably the cause of increased shear stress at the bone-cement interface. The respective influence of section and surface remain to be determined.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 250 - 250
1 Mar 2004
Lefevre N Moussa H Kerboull L Kerboull M Courpied J
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Aims: The purpose of this prospective randomized study was to report on the minimal 10-year follow-up results of a consecutive series of cemented total hip arthroplasty according to the surface finish of the femoral implant. Methods: Between January 1988 and December 1989, 311 total hip arthroplasties were performed in 286 patients. Implants were of Charnley Kerboull design combining a 22.2-mm femoral head and an all-polyethylene socket. The cemented femoral implant was available in two configurations: polished (Ra = 0.4 μm) and matte (Ra = 3 μm). The polished stem (MK III, Stryker Howmedica) was implanted in 166 hips, and the matte stem (CMK 3, Vecteur Orthopedic) in the remaining 145. The mean age of the patients was 63.6 years. Results: At the minimum 10-year follow-up evaluation, 187 patients (204 hips) were still alive and had not been revised at a mean of 11.7 years (10–14 years), 15 patients (15 hips) had been revised, 54 patients (58 hips) had died from unrelated causes, and 30 patients (34 hips) were lost to follow-up. The mean d’Aubigné hip score was 17.7 ± 0.3 at the latest follow-up. The survival rate at 13 years, using radiologic loosening as the end-point, was 97.3 ± 2.6% (95% confidence interval, 92.2 to 100%) for polished stems, versus 78.9 ± 5.8% (95% confidence interval, 67.6 to 90.3%) for matte stems (log-rank test, p = 0.0001). Conclusions: This study demonstrated that cemented fixation of femoral stems was significantly more reliable in the long-term with a polished surface.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 224 - 224
1 Mar 2004
Moussa H Madi F Kerboull L Courpied J Kerboull M
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Aims: The aim of this open prospective study was to evaluate the minimum 2-year follow-up outcome of a consecutive series of low friction total hip arthroplasties combining zirconia on polyethylene. Methods: Between January 1997 and June 1999 fifty-five total hip arthroplasties were performed in 51 patients. The mean age was 52.2 ± 12 years. The 22.2-mm femoral head made of zirconia ceramic was secured to the femoral component through a Morse taper that had an angle of 11°25 for 27 hips and 5°40 for 33 hips. All prostheses were of Charnley-Kerboull design. Clinical results were evaluated according to the Merle d’Aubigné hip score. Wear of the acetabular component and periprosthetic osteolysis was measured on serial radiographs of the pelvis. Results: The mean follow-up of the series was 32 months (24 to 48 months). No patient was lost to follow-up. The mean functional hip score significantly increased from 12.2 ± 2.6 preoperatively to 17.8 ± 0.2 at the latest follow-up (paired Student’s t test, p < 0.0001). None of the acetabular or femoral component had migrated. Wear of the socket was always undetectable on plain radiographs. However, lytic endosteal lesions of the calcar were observed in 19 of the 55 arthroplasties (34.5%). These lytic lesions appeared between the first and second postoperative year. Conclusions: Early calcar osteolysis observed in this study can be related to either run-in wear or to preliminary severe wear. The authors do not recommend further use of zirconia ceramic until long-term follow-up studies are available.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages - 61
1 Mar 2002
Hamadouche M Madi F Kerboull L Courpied J Kerboull M
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Purpose: New surfaces have been developed to reduce polyethylene wear. The zircone ceramic surface appears to have a theoretical advantage due to its interesting tribologic properties. The purpose of this prospective study was to assess clinical and radiological outcome at a minimal two years follow-up in a consecutive series of total hip arthroplasties using the polyethylene zircone junction.

Material and methods: La series included 56 total hip arthroplasties performed in 49 patients (30 women and 19 men), mean age 52.2 ± 12 years (25–76). Primary degenerative hip disease was the aetiology in 43% of the cases, dysplasia in 27%. The femoral component was made of 316L steel with a 11°25 Morse cone for 27 hips and a 5°40 cone for 29 hips. The femoral head measured 22.2 mm and was made of polycrystaline zircone ceramic stabilised in the tragonal form with yttrium (Y-TZP). All the arthroplasties were performed via transtrochanteric access using cemented Charnley-Kerboull implants. Clinical outcome was assessed with the Merle-d’Aubigné score. Classical landmarks on the AP pelvis views were used to assess implant migration. Cup wear was measured using the Livermore method. Actuarial survival curves were plotted.

Results: Mean follow-up was 32 months (24–48). None of the patients were lost to follow-up. The mean functional score at last follow-up was 17.8±0.2 (16–18) versus 12.2±2.6 before arthroplasty (Student t test for paired variables, p < 0.0001). No cases of migration of the femoral or acetabular component were observed. Acetabular wear was always less than the precision of the measurement method. Osteolytic lesions were however observed as endosteal defects in the Merkel region measuring less than 1 cm2, observed in 18 out of the 56 hips (32%). These osteolytic lesions generally appeared between the first and second year and did not appear to progress.

Discussion: Osteolysis in the Merkel region appeared early for one third of the hips, despite the absence of cup polyethylene wear. It would be reasonable to be prudent when using zirone ceramic heads. We are continuing our close follow-up of this group of patients. In addition, measurements of wear and migration are being made using the EBRA method.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages - 28
1 Mar 2002
Charrois O Kerboull L Vastel L Courpied J Kerboull M
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Purpose of the study: Extensive loss of femoral bone subsequent to implant loosening raises an unsolved problem. The purpose of this work was to examine mid-term results of 18 iterative total hip arthroplasties with femoral reconstruction using massive allografts performed between 1986 and 1997.

Materials and methods: Using the Vives classification, the femoral bone lesions were grade 3 (n = 2) and grade 4 (n = 16). The reconstruction was achieved with radiated massive allografts measuring 11 to 35 cm implanted in a split host femur. Charnley-Kerboull implants with a long stem were cemented in the reconstructed femurs.

Results: Mean follow-up was 4 years 10 months (range 2 to 9 years). Nine complications in 7 hips were observed: 6 trochanter nonunions, two recurrent prosthesis dislocations and 1 femoral fracture. At last follow-up, the functional result was excellent or very good in 12 hips (Merle d’Aubigné classification). A stable fixation persisted for 15 implants and 3 had loosened. Graft-host femur consolidation was achieved in all cases except 1. There were 3 cases with extensive resorption of the graft including 2 associated with loosening of the femoral component.

Discussion: Reconstruction of the femur after extensive bone loss using a massive allograft appears to be a useful method for restoring bone tissue and providing immediate mechanical support for the femur.


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 4 | Pages 658 - 663
1 Jul 1990
Sedel L Kerboull L Christel P Meunier A Witvoet J

Total hip replacement using an alumina head and socket and a titanium alloy stem is evaluated in a series of patients under 50 years of age. Between April 1977 and December 1986, 86 such replacements were performed in 75 patients, but mainly because patients had difficulty travelling from Africa, only 71 hips were followed up adequately; of these, 56 were primary procedures and 15 revisions. Survivorship analysis showed that 98% of the prostheses were retained for 10 years. On clinical and radiological examination 51 of the 71 hips were stable and acceptable, 15 had radiological changes on the acetabular side, and one on the femoral side; four other cases had clinical and radiological changes suggesting impending failure, possibly because fixation of the socket was inadequate. There were no differences between the results of the primary procedures and those of revisions. In these young patients, the results seem better with alumina-on-alumina hips than with other varieties, possibly because of their remarkably low wear.