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Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_16 | Pages 93 - 93
1 Dec 2015
Langvatn H Dale H Engesæter L Schrama J
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The aim of this study was to validate the information on operating room ventilation reported to the Norwegian Arthroplasty Register (NAR). We then wanted to assess the influence of operating room ventilation on the rate of revision due to infection after primary THA performed in operating rooms with conventional ventilation, “greenhouse”–ventilation and Laminar Airflow ventilation (LAF).

We identified cases of THA revisions due to deep infection and the type of ventilation system reported to the NAR from the primary THA. We included 5 orthopaedic units reporting 17947 primary THAs and 136 (0.8%) revisions due to infection during the 28 year inclusion period from 1987 to 2014. The hospitals were visited and the current and previous ventilation systems were evaluated together with the hospitals head engineer, and the factual ventilation on the specific operating rooms was thereby assessed. The association between revision due to infection and operating room ventilation was estimated by calculating relative risks (RR) in a Cox regression model.

73% of the primary THAs were performed in a room with LAF, in contrast to the reported 80 % of LAF. There was similar risk of revision due to infection after THA performed in operating rooms with laminar air flow compared to conventional ventilation (RR=0.7, 95 % CI: 0.2–2.3) and after THA performed in operating rooms with “greenhouse”-ventilation compared to conventional ventilation (RR=1.2, 0.1–11).

Surgeons are not fully aware of what kind of ventilation there is in the operating room. This study may indicate that, concerning reduction in incidence of THA infection, LAF does not justify the substantial installation cost. The numbers in the present study are too small to conclude strongly. Therefore, the study will be expanded to include all hospitals reporting to the NAR.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 111 - 111
1 Mar 2009
Fevang B Lie S Havelin L Engesæter L Furnes O
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Objective: To study the incidence of joint replacement procedure, arthrodesis, and synovectomy among patients with chronic inflammatory joint disease during the period 1994 to 2004.

Methods: Data from the Norwegian Arthroplasty Register was used to find the number of joint replacement procedures performed in Norway 1994 – 2004. The incidences of arthrodeses and synovectomies were obtained from the Norwegian Patient Register. Incidence rates were calculated based on age, year, and gender specific population rates for the Norwegian population, obtained from Statistics Norway.

Results: There were 8268 primary joint replacements, 3554 arthrodeses, and 5012 synovectomies performed in patients with inflammatory arthritis (IA) during the study period. A reduction in joint replacement procedures and synovectomies took place during the period 1994 to 2004, in patients with IA. For the oldest patients (80 years and older), no such trend was found. During the same time period, the incidence of joint replacements due to osteoarthritis increased. A significant reduction in the incidence of arthrodesis procedures was also found for the total study group, but not for the different subgroups.

Conclusion: The incidence of joint replacements and synovectomies among patients with chronic inflammatory joint disease decreased from 1994 to 2004. This may be the result of improved medical treatment of these patients.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 35 - 35
1 Mar 2009
Lie S Pratt N Engesæter L Havelin L Ryan P Graves S Furnes O
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There is an increased early postoperative mortality (operation risk) after joint replacement surgery. This mortality is normally associated with cardiovascular events, such as deep venous thrombosis, pulmonary embolism, and ischemic heart diseases.

Our objective was to quantify the magnitude of the increased mortality and how long the mortality after an operation persists.

We focused on the early postoperative mortality after surgery for total knee and total hip replacements from the national registries in Australia and Norway, which cover more than 95% of all operations in the two nations. Only osteoarthritis patients between 50 and 80 years of age were included. A total of 244.275 patients remained for analyses.

Smoothed intensity curves were calculated for the early postoperative period. Effects of risk factors were studied using a non-parametric proportional hazards model.

The mortality was highest immediately after the operation (~1 deaths per 10.000 patients per day), and it decreased until the 3rd postoperative week. The mortality was virtually the same for both nations and both joints. Mortality increased with age and was higher for males than for females.

A possible reduction of early postoperative mortality is plausible for the immediate postoperative period, and no longer than the 3rd postoperative week.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 90 - 90
1 Mar 2009
Furnes O Lie S Engesæter L Havelin L
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Background: During the 1990s a change in operative technique for primary hip replacement took place in Norway. This study was designed to measure the revision rate in different time periods in cemented Charnley total hip replacements reported to the Norwegian Arthroplasty Register.

Patients and methods: 26 873 primary cemented Charnley total hip replacements reported to the Norwegian Arthroplasty Register in the time periods 1987–91, 92–96, 97–01 and 2002–05 were studied. Only hips with Palacos and Simplex cements with and without antibiotic were studied. To compare the time periods Kaplan Meier analysis was used. To adjust for differences in approach to the hip, age, sex and use of systemic antibiotic prophylaxis Cox regression was used.

Results: There was 28 % less risk of revision due to all causes in the time period 1997–01 compared to 1987–91 (RR=0.72 (95% CI 0.60–0.86), p< 0,001). There was inferior result in the time period 1992–96 compared to 1987–91, but from 1997 there has been an improvement of results due to fewer aseptic loosenings of the femoral component (RR 0.44 (95% CI 0.35–0.56), p< 0.001). There was however more luxations in the later period, and there was no improvement in revisions due to aseptic loosening of the acetabular component.

Conclusion: There has been an improvement in revision rate of the cemented Charnley prosthesis the last two time periods, due to fewer aseptic loosenings of the femoral component. The reason is probably better technique of component placement and better cementation technique. In the future prevention of luxation and better cementation technique of the acetabulum should also be emphasised.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 250 - 250
1 Mar 2004
Furnes O Lie S Espehaug B Vollset S Engesæter L Havelin L
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Aims: To assess the influence of hip disease on the risk of revision, we studied different disease groups among 53 698 primary total hip replacements (THRs) reported to the NAR between 1987 and 1999. Methods: the revision rate in the 8 most common hip diseases were compared by kaplan-meier survival analyses and cox multiple-regression. To eliminate the influence of prosthesis type a subgroup of 16217 charnley prostheses were analysed. Results: we found statistically significant differences in prosthesis survival among the hip diseases, but after adjustment for prosthesis type most of the differences disappeared. In patients ≤60 years, 59% of the prostheses were uncemented and 33% could be defined as inferior uncemented prostheses. In the charnley subgroup only complications after fracture of the femoral neck had an increased risk for revision compared to primary osteoarthritis (rr 1.5, p=0.005). 10 years survival for cemented charnley prostheses with osteoarthritis was 92.0% for patients ≤60 years and 93.5% for patients > 60 years. Conclusions: after adjustment the results for all disease groups were good. The results of thrs in disease-groups where patients are operated on at a young age were less good because these patients had often been given inferior uncemented prostheses.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 207 - 208
1 Mar 2004
Engesæter L
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Foot pain in children is common. The reason for the pain can usually be determined from history and physical examination, but often a radiogram is necessary. The causes for painful foot can be divided into following categories:

• Trauma (Fractures, sprains, soft tissue injuries, puncture wounds, overuse syndromes)

• Infections (Osteomyelitis, septic arthritis, ingrown toe-nail)

• Arthritis (Degenerative, juvenile rheumatoid)

• Osteochondroses (Köhler, Freiberg, Sever) • Deformities (Bunions, tarsal coalitions)

• Tumors

• Others The specific treatment depends on the diagnosis and occasionally on the age of the child.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 258 - 258
1 Mar 2003
Engesæter L Furnes O Espehaug B Lie S Vollset S Havelin L
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Purpose: The outcome of primary total hip arthroplasty (THA) after a previous paediatric hip disease was studied in data from the Norwegian Arthroplasty Register (NAR).

Materials and Methods: 72,301 primary THAs were reported to the NAR for the period 1987 – February 2002. Of these, 5,459 (7.6%) were performed because of sequela after developmental dysplasia of hip (DDH), 737 (1.0%) because of DDH with dislocation, 961 (1.3%) because of Perthes’/ slipped femoral capital epiphysis (SFCE) and 50,369 (70%) because of primary osteoarthritis (OA). Prosthesis survival was calculated by the Kaplan-Meier method and relative risks for revision in a Cox model with adjustments for age, gender, type of systemic antibiotic, operation time, type of operating theatre and brand of prosthesis.

Results: Without any adjustments the THAs for all three groups of paediatric hip diseases had 1.4 – 2.0 times increased risk for revision compared to that of OA (p< 0.001). Due to huge differences in the studied groups, a more homogenous subset of the data had to be analysed. In this subset, only THAs with well documented prostheses, high-viscosity cements and antibiotic prophylaxis both systemically and in the cement were included (16,874 THAs). In this homogenous subset, no differences in the survivals could be detected for DDH without dislocation and for Perthes’/SFCE compared to OA. For DDH with dislocation the revision risk with all reasons for revisions as endpoint in the analyses was increased 3.3 times compared to OA (p< 0.001), 2.7 times with aseptic loosening as endpoint (p< 0.01) and 10 times with infection as endpoint (p< 0.001).

Conclusions: If well-documented THAs are used after paediatric hip diseases the results are just as good as after osteoarthritis, except for DDH with dislocation where increased revision risk is found.