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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLI | Pages 88 - 88
1 Sep 2012
Kumar V Malhotra R Bhan S
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We retrospectively reviewed 54 patients (92 hips) who underwent cementless total hip arthroplasty for bony ankylosis in ankylosing spondylitis between September 1988 and 2002. Clinical assessment was done at follow-up, which envisages assessment of the pain, function, deformities and range of motion using the Harris Hip Score. Radiographic analysis was done. Kaplan-Meier survivorship analysis was done at 5 and 8.5 years using the revision for the removal of femoral component, acetabular component or both due to any cause as the end point.

The mean age of the patients was 25.5 years. The mean duration of follow up was 8.5 years. The average preoperative Harris Hip Score of 49.5 improved to 82.6 post operatively. Post operatively 10 hips had mild to moderate pain. Anterior dislocation occurred in four hips (4.3 %) and sciatic nerve palsy in one hip. Heterotopic ossification was seen in 12 patients, reankylosis rate was 0%. Thirteen arthroplasties were revised due to aseptic loosening. Kaplan-Meier survivorship analysis with revision as end point revealed 98.8% survival at 5 years and 85.8% survival at 8.5 years 11 follow up.

Cementless THA in osseous ankylosis in ankylosing spondylitis is a worthwhile surgical intervention in bony ankylosis. Newfound mobility, manoeuvrability and improved ability to sit comfortably were the outcomes, which alleviated the patients’ daunted morale. However, the technically demanding nature of the procedure should not be underestimated.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 548 - 548
1 Nov 2011
Kumar Malhotra R Bhan S
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Background: Joint replacements are being performed on ever younger patients at a time when average expectancy of life is continuing to rise. Any reduction in the strength and mass of periprosthetic bone could threaten the longevity of implant by predisposing to loosening and migration of prosthesis, periprosthetic fracture and problems in revision arthroplasty.

Aims & Objectives: This study aims to analyse and compare prospectively the femoral periprosthetic stress-shielding around 4/5th and 1/3rd porous coated cementless femoral stems in patients undergoing unilateral cementless total hip replacement done using DEXA scan by quantifying the changes in bone mineral density around femoral component.

Material & Method: Femoral periprosthetic bone mineral density was measured in the seven Gruen Zones with DEXA scan at 2 weeks, 1 years and 2 years after surgery in 60 patients who had undergone unilateral cementless total hip replacement, of which 30 patients had been implanted with 4/5th porous coated stems and other 30 patients with 1/3rd porous coated stems.

Results: At both one and two years postoperatively, bone loss due to stress-shielding was seen in both stems with maximum loss in zone VII and minimum in zone III, IV, V. The maximum mean percentage bone mineral density loss in 4/5th porous coated stems in zone VII was 16.03% at one year and 22.42% at 2 years as compared to loss of 10.07% and 16.01% in 1/3rd porous coated stems. Increased bone loss was seen in patients who had larger diameter stem (> 13.0 mm) and in patients with low bone mineral density in the unoperated hip.

Conclusion: Bone loss as a result of stress-shielding is more pronounced in 4/5th porous coated stems as compared to 1/3rd porous coated stems.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 113 - 113
1 May 2011
Malhotra R Kumar V Eachempati K Bhan S
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Background: Durable long-term independent results with the Low Contact Stress rotating-platform (mobile-bearing) and the Insall Burstein-II (fixed-bearing) total knee prostheses have been reported, but no studies describing either the mid-term or long-term results and comparing the two prostheses are available, to our knowledge.

Methods: Thirty-two patients who had bilateral arthritis of the knee with similar deformity and preoperative range of motion on both sides and who agreed to have one knee replaced with a mobile-bearing total knee design and the other with a fixed-bearing design were prospectively evaluated. Comparative analysis of both designs was done at a mean follow-up period of six years, minimizing patient, surgeon, and observer-related bias. Clinical and radiographic outcome, survival, and complication rates were compared.

Results: Patients with osteoarthritis had better function scores and range of motion compared with patients with rheumatoid arthritis. However, with the numbers available, no benefit of mobile-bearing over fixed-bearing designs could be demonstrated with respect to Knee Society scores, range of flexion, subject preference, or patellofemoral complication rates. Radiographs showed no difference in prosthetic alignment. Two knees with a mobile-bearing prosthesis required a reoperation: one had an early revision because of bearing dislocation and another required conversion to an arthrodesis to treat a deep infection.

Conclusions: We found no advantage of the mobile-bearing arthroplasty over the fixed-bearing arthroplasty with regard to the clinical results at mid-term follow-up. The risk of bearing subluxation and dislocation in knees with the mobile-bearing prosthesis is a cause for concern and may necessitate early revision.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 393 - 394
1 Jul 2010
Kumar V Malhotra R Bhan S
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Background: Joint replacements are being performed on ever younger patients at a time when average expectancy of life is continuing to rise. Any reduction in the strength and mass of periprosthetic bone could threaten the longevity of implant by predisposing to loosening and migration of prosthesis, periprosthetic fracture and problems in revision arthroplasty.

Aims & Objectives: This study aims to analyse and compare prospectively the femoral periprosthetic stress-shielding around 4/5th and 1/3rd porous coated cementless femoral stems in patients undergoing unilateral cementless total hip replacement done using DEXA scan by quantifying the changes in bone mineral density around femoral component.

Material & Method: Femoral periprosthetic bone mineral density was measured in the seven Gruen Zones with DEXA scan at 2 weeks, 1 years and 2 years after surgery in 60 patients who had undergone unilateral cementless total hip replacement, of which 30 patients had been implanted with 4/5th porous coated stems and other 30 patients with 1/3rd porous coated stems.

Results: At both one and two years postoperatively, bone loss due to stress-shielding was seen in both stems with maximum loss in zone VII and minimum in zone III, IV, V. The maximum mean percentage bone mineral density loss in 4/5th porous coated stems in zone VII was 16.03% at one year and 22.42% at 2 years as compared to loss of 10.07% and 16.01% in 1/3rd porous coated stems. Increased bone loss was seen in patients who had larger diameter stem (> 13.0 mm) and in patients with low bone mineral density in the unoperated hip.

Conclusion: Bone loss as a result of stress-shielding is more pronounced in 4/5th porous coated stems as compared to 1/3rd porous coated stems.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 539 - 539
1 Aug 2008
Kumar V Malhotra R Bhan S
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Background: Joint replacements are being performed on ever younger patients at a time when average expectancy of life is continuing to rise. Any reduction in the strength and mass of periprosthetic bone could threaten the longevity of implant by predisposing to loosening and migration of prosthesis, periprosthetic fracture and problems in revision arthroplasty.

Aims & Objectives: This study aims to analyse the femoral periprosthetic stress-shielding following unilateral cementless total hip replacement using DEXA scan by quantifying the changes in bone mineral density around femoral component over a period of one year and identify the factors influencing the bone loss.

Material & Method: Femoral periprosthetic bone mineral density was measured in the seven Gruen Zones with DEXA scan at 2 weeks, 3 months and 1 year after surgery in 20 patients who had undergone unilateral cementless total hip replacement, of which 10 patients had been implanted with 4/5th porous coated CoCr stems and other 10 patients with 1/3rd porous coated titanium alloy stems.

Results: At both 3 months and one year postoperatively, bone loss due to stress-shielding was seen in both stems with maximum loss in zone VII and minimum in zone III, IV, V. The maximum mean percentage bone mineral density loss in 4/5th porous coated CoCr stems in zone VII was 16.03% at 3 month and 22.42% at 1 year as compared to loss of 10.07% and 16.01% in 1/3rd porous coated Ti alloy stems. Increased bone loss was seen in patients who had larger diameter stem (> 13.0 mm) and in patients with low bone mineral density in the unoperated hip.

Conclusion: Bone loss as a result of stress-shielding is more pronounced in 4/5th porous coated CoCr stems as compared to 1/3rd porous coated titanium alloy stems.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 3 | Pages 298 - 303
1 Mar 2006
Bhan S Pankaj A Malhotra R

We compared the safety and outcome of one-stage bilateral total hip arthroplasty with those of a two-stage procedure during different admissions in a prospective, randomised controlled trial in an Asian population. Of 168 patients included in the study, 83 had a single- and 85 a two-stage procedure. Most of the patients (59.9%) suffered from inflammatory arthritis.

The intra-operative complications, early systemic complications, the operating time, positioning of the components, the functional score, restoration of limb length and survival rates at 96 months were similar in the two groups. The total estimated blood loss was significantly lower in patients undergoing a one-stage procedure than in patients who had a two-stage procedure, but the transfusion requirements were significantly higher in the former group (p = 0.001). The hospital stay was significantly shorter in the one-stage group, 7.25 days (sd 1.30; 5 to 20) compared with 10 days (sd 1.65; 8 to 24) in the two-stage group (p = 0.023). We believe that a one-stage procedure is safe and appropriate in our population.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 11 | Pages 1549 - 1552
1 Nov 2005
Malhotra R Bhan S Kiran EK

We present seven patients with recurrent haemarthroses after total knee arthroplasty, caused by an inherent platelet function defect. These patients developed painful knee swelling, persistent bleeding and/or wound breakdown, a platelet factor 3 availability defect being identified in all cases. Surgical exploration, with joint debridement, lavage and synovectomy, was performed in four patients who did not improve with conservative therapy. Histopathological examination of synovium revealed a focal synovial reaction with histiocytic infiltration, and occasional foreign-body giant cells. One patient required an early revision because of aseptic loosening of their tibial component. The condition was treated by single-donor platelet transfusions with good results. The diagnosis, management, and relevance of this disorder are discussed.


The Journal of Bone & Joint Surgery British Volume
Vol. 86-B, Issue 7 | Pages 1090 - 1090
1 Sep 2004
LOGANI V EACHEMPATI KK MALHOTRA R BHAN S


The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 2 | Pages 320 - 321
1 Mar 1996
Mandal S Bhan S