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Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 557 - 558
1 Nov 2011
Hildebrand KA Monument MJ
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Purpose: The presence of hemarthrosis during joint injury is a potential inciting stimulus in the genesis of joint capsule fibrosis. Using a rabbit model of posttraumatic knee joint contracture, our hypothesis was that, bone marrow-derived elements of hemarthrosis rather than simply the presence of blood in the joint, trigger the induction of capsule fibrosis in post-traumatic joint contracture.

Method: 35 Skeletally mature New Zealand White female rabbits (12–18 months old, 5.5 ± 0.5 kg) were randomly assigned to one of five groups: Immobilization-Only (IMO), Immobilization+ Bone Marrow (IMBM), Immobilization+ Peripheral Blood (IMPB), Bone Marrow-Only (BMO), and Controls. Surgeries: Immobilization groups had one knee joint fixed at full flexion with a Kirschner wire drilled through the tibia, passed posterior (extra-articular) to the knee joint and bent around the femur. Bone marrow groups had cortical windows removed from the non-articular cartilage portion of the medial and lateral femoral condyles. In the IMPB group, autologous peripheral venous blood was injected into the immobilized knee joint to recreate a non-traumatic hemarthrosis. The control group did not have any intervention. Joint angle measurements: After 8 weeks, rabbits were euthanized, all muscular tissue was removed and maximum extension angle of the joints with intact capsule was measured using a standard torque applied via a custom made rabbit knee gripping device attached to a MTS TestStar II. Each joint was cycled 5 times (0.2 Nm) and the average of 5 cycles was calculated. Statistical analysis consisted of a one-way ANOVA with posthoc Scheffe test (significance p < 0.05). Data are presented as mean +/ − standard deviation.

Results: The IMBM (n=8) and IMPB (n=7) groups had significantly greater contractures (52 +/ − 12 and 58 +/ − 13 degrees, respectively) when compared to the BMO (n=7) and control (n=6) groups (32 +/ − 10 and 32 +/ − 13 degrees, respectively). The IMO group had average contracture measures of 44 +/ − 15 degrees. There was no statistically significant difference between the IMBM and IMPB groups.

Conclusion: The present study showed differences in the contracture severity of the immobilized knees associated with hemarthrosis compared to other experimental and control groups. There does not appear to be a difference whether the hemarthrosis arose from a fracture (bone marrow) versus peripheral blood in rabbits. Future work will look at reversibility of contractures in the various groups. Studies on the joint capsule will evaluate myofibroblast numbers in concert with mast cell and neuropeptide distribution based on our previous work. Such knowledge will aid the prevention and treatment of the difficult and disabling problem of contracture formation after joint injury.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 161 - 161
1 Mar 2010
Seo S Kim C Ha D Chung H
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The purpose of this study in to investigate the role of infrapatellar fat pad on primary total knee arthroplasty. We evaluated 100 patients who had been undergone TKA from August 2002 to July 2003, with open box posterior substituting femoral component implant (Scorpio PS Knee). The study was performed prospectively and randomly allocated. We divided two groups. Group 1 (50 knees) was preserved infrapatellar fat pad and repaired fad at wound closure. Group 2 (50 knees) was excised infrapatellar fat pad as possible and repaired only joint capsule. We analyzed and compared clinical results of Knee Society knee (KS) score, function score, patellar score and Insall-Salvati ratio in both groups. The complications of each group were evaluated. Patients were followed up for mean 40 months(17~52 months).

Mean KS score was 91.9 (91.94±5.58) in Group 1 and 90.9(90.92±6.38) in Group 2. Mean function score was 81.6(81.64±13.18) in Group 1 and 83.7(83.79±17.71) in Group 2. Mean patellar score was 29.9(29.89±9.10) in Group 1 and 27.9(27.90±1.80) in Group 2. And mean patellar height as Insall-Salvati ratio was 1.19(1.19±0.17) in Group 1 and 1.23(1.23±0.11) in Group 2. The differences between the Group 1 and Group 2 in all of index were statistically insignificant. In complications, 2 cases of recurrent hemarthrosis were observed in Group 1 patients.

We concluded The difference of clinical outcomes whether infrapatellar fat pad was excised or not were statistically insignificant. However, preservation of infrapatellar fat pad on open boxed PS TKA showed unique complications such as recurrent hemarthrosis which might be caused by fat pad adhesion to intercondylar notch. We propose that infrapatellar fat pad on primary PS TKA with open box design would like to be excised for prevention of unique complications.


Bone & Joint Open
Vol. 2, Issue 8 | Pages 618 - 630
2 Aug 2021
Ravi V Murphy RJ Moverley R Derias M Phadnis J

Aims

It is important to understand the rate of complications associated with the increasing burden of revision shoulder arthroplasty. Currently, this has not been well quantified. This review aims to address that deficiency with a focus on complication and reoperation rates, shoulder outcome scores, and comparison of anatomical and reverse prostheses when used in revision surgery.

Methods

A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) systematic review was performed to identify clinical data for patients undergoing revision shoulder arthroplasty. Data were extracted from the literature and pooled for analysis. Complication and reoperation rates were analyzed using a meta-analysis of proportion, and continuous variables underwent comparative subgroup analysis.