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Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 528 - 528
1 Nov 2011
Hourlier H Marié F Fennema P Reina N De Lestang M
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Purpose of the study: Conventional techniques for implantation of a TKA allow a neutral mechanical axis (HKA 180±3) in 70 to 86% of patients. The purpose of this work was to evaluate the contribution of intraoperative radiologic assistance for this objective.

Material and methods: We conducted a prospective randomised study in a single-operator consecutive series of cemented TKA, model TC-SB, excluding revisions and frontal deviations > 25. The series included 65 women and 39 men, mean age 73 years. All operations were performed on a radiolucent table. An extramedullary guide was used for the tibial cut and an intramedullary guide for the femoral cup. Patient randomisation was done after the cuts. According to the randomisation, the orientation of the cuts in the frontal plane was measured radiographically using a fluoroscope and an aiming plate situated on the hip, then the ankle. Secondary cuts were made if the angular deviation was greater than 1°. The position of the TKA assisted by the fluoroscope (group R+, n=52) and that of the non-assisted TKA (group R-, n=52) was assessed on the digitalised goniometry.

Results: Mean operative time was 70 minutes in group R+ and 59 minutes in group R-. In group R+, the mean mechanical alignment was 3.9 varus preoperatively and 0.13 valgus postoperatively (5 valgus to 3 varus) with 91% in the ±3 range. In group R-, the mean mechanical alignment was 6.7 varus preoperatively and 0.06 varus postoperatively (6 varus to 5 valgus) with 80% of the cases in the ±3 range. The standard deviation was 2 in group R+ and 2.7 in group R-, with no significant difference.

Discussion: The accuracy of the implantation obtained with the conventional instrumentation for the TC-SB prosthesis is among the best reported in the literature. Intraoperative radiological assistance enabled a tighter spread of the results around the mechanical alignment. The technique was simple to use and precise. The mean duration of exposure to the fluoroscope was 3 s (PDS 3 – 35 gray cm2).

Conclusion: We reserve this assistance in priority for patients with major bone deformities or medullary obstacles.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 538 - 538
1 Nov 2011
Gabrion V Gabrion A Sérot J Mertl P De Lestang M
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Purpose of the study: Dementia in the elderly subject aged over 75 years is currently an important public health problem. An important part of the activity in orthopaedic surgery involves this age group. In 2007, 16,812 elderly persons aged over 75 years were hospitalised in our University Hospital (769 in orthopaedic surgery): 1380 patients were considered demented (40 in orthopaedic surgery). The purpose of this work was to evaluate the cognitive function of this population in a teaching hospital unit of orthopaedic and traumatology surgery where the prevalence of dementia appears to be underestimated.

Material and methods: Data were collected over a period of four years. This study concerned 113 patient, including 83 women, mean age 81.8 years (range 75–92). The reason for hospitalisation was predominantly fracture of the proximal femur (73%); thirty patients had hip, knee or shoulder arthroplasty and 24 other situations. The Mini Mental State Examination (MMSE) was performed.

Results: The MMSE could be interpreted for 100 patients: < 24 for 33, 24 to 26 for 29 and > 27 for 38. Among the 24 patients with no cognitive disorder known before hospitalization (nine patients known to be demented were removed from the analysis) and for whom the MMSE was completed entirely, the most frequent alterations were noted for attention, calculation, and recall-memory items.

Discussion: Finally, one-third of the subjects aged over 75 years and hospitalized in our unit presented signs of altered cognitive function according to the MMSE(< 24). This score is one of the criteria for frailness of the elderly subject. This population has an unstable precarious medicosocial status with defective adaptation to stress and change in environment. These persons are exposed to a high risk of morbidity, mortality, dependence, longer hospital stay and institutionalization. The purpose of this screening is to improve management for these patients by proposing more specifically adapted care.

Conclusion: It is thus indispensable to screen for cognitive disorders systematically in patients aged over 75 years hospitalized in a surgery unit. The MMSE score can be used for this purpose. This work is in favour of a physician or better a geriatrician within the unit who could be financed directly by his-her own sector of activity.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 508 - 508
1 Nov 2011
Manopoulos P Havet É Mertl P Parizon P Lardanchet J De Lestang M
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Purpose of the study: Restrained implants with intrinsic stability guaranteed by a large central stem have been developed for revision knee arthroplasty, irrespective of the underlying cause. Successful restraint implies excellent fixation of the prosthetic implants which can be obtained using press-fit centromedullary stems. The purpose of this work was to assess the long-term results of this mode of fixation in this indication and to search for clinical correlations with potential radiological images around the stems.

Material and methods: We report 46 cases of Sigma®PFC TC3 revision total knee prostheses reviewed retrospectively at two years with a mean follow-up of eight years. Mean age at surgery was 68 years. Revision was indicated for aseptic loosening (n=24) and septic loosening (n=22). The knee society criteria were used for the clinical evaluation. Radiographic measurements were made semiautomatically with the Imagika® software.

Results: The mean clinical score improved from 42 points preoperatively to 84.7 at two years and 83.7 at last follow-up. Outcome was excellent (n=30), good (n=7), fair (n=1) and poor (n=1). The mean function score improved from 34.3 preoperatively to 69.1 at two years and 64.2 at last follow-up. Radiographic alignment was correct in all cases. The press-fit effect was observed for 63% of the femoral implants and 76% for the tibial implants. Around the stems, 57% of the implants exhibited condensation lines and 23% lucent lines measuring less than 2 mm. There was no relation between radiological findings and the clinical or functional scores. There were two failures, one for frontal instability at six years and the other for aseptic loosening at eight years. Excepting these two cases, there was one case of femoral implant migration with no clinical expression. For all other patients, the radiographic image remained unchanged between the two year check-up and the final follow-up.

Discussion: Thee presence of lucent lines or condensation lines is well known for this type of implant with long centromedullary stems. Nevertheless, this is the first clinical series evaluating the clinical impact of these radiographic images. In our opinion, these images are related to the relative mobility of these implants which should be checked regularly, although no long-term clinical expression occurs. For us, this type of implant enables good function and long-term stability.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 518 - 518
1 Nov 2011
Hourlier H Liné B Fennema P Blaysat M De Lestang M
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Purpose of the study: The risk of homologous blood transfusion for primary total knee arthroplasty (TKA) varies between centres from 4 to 72%. Measurement of mean blood loss for patients undergoing primary total hip or knee arthroplasty led us to adopt a global blood-sparing protocol.

Material and methods: This was a prospective observational study involving 90 TKA (TC-SB) implanted by one surgeon in 56 women and 33 men, mean age 74 years, ASA 3 for 29%, mean BMI=31. Programmed autologous transfusion and blood recovery were not applied. Alpha epoeitine (EPO was administered in the preoperative period in accordance with the predicted serum haemoglobin at discharge. Tranexamic acid (TA) was injected intravenously during the operation.

Results: The mean operative time was 63 minutes, mean tourniquet time 51 minutes. During the perioperatively period, the mean 7-day blood loss was 566±254 ml red cells and 1560±643 total blood. Mean serum haemoglobin at discharge was 1.0 g/dl. Fourteen percent of patients had a postoperative serum haemoglobin less than 10 g/dl (lowest level 8.4 g/dl). One patient had a transfusion; this was a man in his nineties who was operated on without a tourniquet and without TA because of a poor arterial system. Nearly 86% of patients received TA with a significant (p< 0.05) decrease in bleeding compared with those who did not receive TA (365 ml total blood). EPO was delivered for 22% of patients (2.8 injections on average) to reached 14.2 g/dl the day before the operation.

Discussion: This overall strategy for blood sparing enabled us to reduce the risk of transfusion and limit costs. In this series, the prescription of EPO was not targeted to reach a set level preoperatively but was based on the predicted serum haemoglobin level at discharge. Thus seven patients with a preoperative haematocrit below 39 did not receive EPO. None of these patients were transfused. Their discharge haemoglobin was between 10.7 and 12.4g/dl. Use of TA should be included in the calculation of the predicted discharge haemoglobin level in order to better determine candidates for EPO injections.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 275 - 276
1 Jul 2008
GABRION A PARIZON P HAVET E PATOU A ALOVOR G MERTL P DE LESTANG M
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Purpose of the study: Osteosynthesis procedures proposed for fractures of the proximal humerus have evolved greatly since the development of anterograde nailing systems with the objective of providing a conservative surgical solution for sometimes complex fractures. We analyzed retrospectively the results obtained in a consecutive series of 30 patients treated in our unit with a Telegraph® nail.

Material and methods: Between March 2001 and August 2003, 39 patients presenting fractures of the proximal humerus were treated with a Telegraph® nail. Accorrding to the Duparc classification, the fractures were: 17, 11 ST+T, 4 CT II, and 7 CT III. Five patients died before the review presented here. Four CT III fractures presented material disassembly early and required revision with a hemiarthroplasty. For the 30 patients reviewed here, we noted the Constant score and the results of the Matsen test as well as radiographic findings.

Results: Mean follow-up for the 30 patients was 16 months (range 6–33). Mean age at trauma was 58.7 years (range 19–91). The mean Constant score was 57.4 (range 16–84) with 72% after weighting. The Matsen test was positive for 59%. Subjectively, 69% of patients were satisfied or very satisfied. There were several complications: secondary intraoperative shaft fracture treated orthopedically, four nonunions of the surgical neck, four tuberosity migrations, three cases of head necrosis, two subacromial impingements (one with rotator cuff tear). Nonunion was generally observed with static locking and in one case with an oversized nail. We were unable to identify any factor predictive of head necrosis due to the small number of cephalotuberosity fractures. Disassembly was generally observed in patients with an initially displaced fracture with periosteal rupture, osteoporosis and old age.

Discussion and conclusion: Our results are less satisfactory than others published in the literature for series using this material and it is difficult to compare with results for series using other types of material because the study criteria were highly variable. Although all fractures in this series, including the most complex, appear to benefit from this nailing system, we did note that complications were not exceptional even though certain compliations observed were related to our learning curve. Surgeons should be aware that the planned option can be changed intraoperatively. Arthroplasty may be necessary in certain cases if the conditions are not adequate for stable osteosynthesis.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 266 - 266
1 Jul 2008
GABRION A ELFEKIH N BELLOT F VERNOIS J JARDÉ O DE LESTANG M
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Purpose of the study: The aim of this work was to compare the long-term clinical, ultrasonographic and iso-kinetic results obtained with two approaches to repair of the torn Achilles tendon.

Material and methods: The patients were reviewed at mean six years follow-up (range 2–12 years) and served as their own control. The series was composed of two groups of ten patients. The first group underwent open suture (OS) (mean age 48 years, age range 38–64 years) and the second was treated percutaneously with Tenolig® (PCS) (mean age 43 years, age range 25–68 years). The Mann, McComis and Kitaoka scores were noted as was the distance from the heal to the ground in one leg stance (comparison with opposite side). Cybex® was used to measure the isokinetic force and an ultrasound control was performed (tendon structure, dimensions).

Results: The calf of the operated side displayed amyot-rophy compared with the healthy side in all cases of PCS (mean 2 cm, range 0.5–6 cm). The heal-ground distance was often smaller compared with the healthy side in PCS. The Mann scores were equivalent for OS and PCS. The Kitaoka and McComis scores were, on average 86 (80–100) and 94 (60–95) respectively for OS versus 82 (85–100) and 91 (60–95) for PCS. Mean caliber of the operated Achilles tendon increased compared with the healthy side for both suture techniques. Isokinetic force was 3–6% greater with OS for peak force, average force, and total work.

Discussion and conclusion: Both techniques have specific complications: recurrent tears and sural nerve injury for PCS, risk for the skin and adherences for OS. The long-term outcome after PCS of the Achilles tendon is comparable with that of OS in terms of healing quality. Recorded values are however slightly higher with OS. Our results are in line with data in the literature. OS can be reserved for particularly active patients who wish to recover maximum function.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 137 - 137
1 Apr 2005
Havet E Berthelet J Gabrion A Mertl P de Lestang M
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Purpose: We report a series of 78 total hip arthroplasty revisions using a locked femoral stem, Ultime.

Material and methods: These patients presented aseptic loosening (88%) and septic loosening (12%). Fracture was associated in 17%. The preoperative Postel Merle d’Aubligné (PMA) score was 10.2 points. Using the Vives-SOFCOT classification, 29% of the loosenings were stage I, 37% stage II, 24% stage III, and 10% stage IV. All fractures were associated with lossening. We used a femoral window in 57% and trochanterotomy in 14 cases. The first eight patients in this series had an allograft (impacted piecemeal). Most of the patients resumed weight bearing the first week. The PMA score was used to assess outcome. AP and lateral views were used to evaluate stem-bone contact and cortical thickness at three levels.

Results: Early complications were phlebitis (n=1) and superficial haematoma (n=5). Late complications were dislocation (n=6), stem fracture (n=2), deep infection (n=3). At last follow-up, 81% of the aseptic loosenings, 77% of the septic loosenings, and 70% of the fractures on stem had a good or excellent PMA score with a mean gain of 4, 5, and 1 points respectively. Bone reconstruction showed an increase in internal cortical (2 to 4.4 mm) and stem-bone contact increased in the lower two-thirds of the stem. Allografts did not improve results. Furthermore, 28% of the patients had hip pain which could not be related to clinical findings or implant characteristics. Half of the patients were reoperated.

Conclusion: In this series, functional improvement was similar to that in published series. The femoral window facilitated the procedure and decreased intraoperative complications. The Ultime prosthesis met the objectives set by the manufacturer, i.e. primary stability and bone reconstruction authorising subsequent revision.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 142 - 142
1 Apr 2005
Gabrion A Havet E Evaillard M Vernois J Mertl P de Lestang M
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Purpose: Deep infections of the operative bed are rare but serious complications of first-intention total hip arthroplasty. Data from French series are scarce. We present a study of incidence, characteristic features and potential risk factors using a consecutive series of 790 implants performed during first-intention procedures in the same university hospital.

Material and methods: All patients who underwent first-intention surgery from November 1995 to May 1999 were included. We collected demographic, clinical, and therapeutic data. Deep infection was defined as bacteriological demonstration of the infectious agent from at least two intra-operative specimens during the revision procedure. Patient follow-up ranged from one month to four years. Univariate analysis was used to search for potential risk factors. The chi-square and Fischer exact tests were applied.

Results: Overall incidence was 1.77 deep infections for 100 operations (95%IC 0.84–2.7). Mean time to development ranged from 14 days to 32 months. Eleven infections were recognised within the first year and three after one year. Two risk factors were identified: absence of systemic antibiotic prophylaxis (relative risk = 4.74, p=0.03), and drainage discharge after 48 hr (relative risk = 3.62, p=0.02). Other variables associated with infection with a relative risk greater than 2 were obesity, corticosteroid therapy, and haematoma or postoperative wound healing problem.

Conclusion: The incidence found in this series is slightly higher than generally described in other countries. This study has incited us to revisit our protocols for preoperative skin preparation and to establish a systemic antibiotic prophylaxis.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 34 - 34
1 Jan 2004
Gabrion A Jarde O Hvet E Mertl P de Lestang M
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Purpose: Total ankle arthroplasty remains a difficult procedure. Some patients require revision surgery for arthrodesis.

Material and methods: We report nine patients with total ankle arthroplasties mainly implanted for post-traumatic osteoarthritis whose results deteriorated, requiring arthrodesis. One of these patients had rheumatoid arthritis.

Revision surgery was performed six months to seven years after arthroplasty. Arthrodesis was required for pain related or not to implant loosening or talar necrosis. One patient developed a major deviation of the hind foot secondary to progressive loosening. One patient developed infection early. An iliac graft was used to fill the bone defect in eight patients. An anterior plate-screw fixation was used for six patients, crossed screws for one, a tibiotalar nail for one, and an external fixator for one (with infection).

Results: Eight patients achieved bone healing with good pain relief. The functional result depended on the type of arthrodesis: talocrural alone or extended to the torsion couple.

Discussion: The evolution of ankle prostheses toward better bone sparing has allowed, in our experience, for revision arthrodesis under relatively good conditions using an iliac graft. We have not preferred one standard type of fixation but the anterior plate fixation has provided excellent stability.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages - 69
1 Mar 2002
Jardé O Havet E Mertl P de Lestang M
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Purpose: We reviewed 30 cases of osteochondrial lesions of the astragalus dome treated surgically.

Material and methods: Among the 30 patients, 17 practised sports and 24 had a history of trauma. Delay to surgery was ten months. All patients were treated by curettage using perforations according to Pridie. There were 11 direct approaches, 13 malleolar osteotomies and six arthroscopies. Cancellous grafts completed the treatment in six cases.

Results: Mean follow-up was three years seven months (minimum two years). All the patients had an arthroscan at last follow-up. The postoperative results were assessed according to clinical and arthroscan criteria.

Discusion: We emphasise the importance of the Fracture Osteonecrosis Geode (FOG) classification system and the subsequent pathophyisiological and prognostic conclusions. The Berndt and Harty classifications should be abandoned. Only symptomatic lesions should be treated. Surgical treatment (arthroscopy or direct access with cancellous graft) is required for efficacy at this stage. Surgical treatments provides very good results in 75% of the cases with pain relief and improved walking distance. We advocate arthroscopic perforation curettage for localised necrosis. In case of major substance loss, cancellous grfat requires a direct access.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages 25 - 25
1 Mar 2002
Jarde O Trinquier-Lautard J Garate F de Lestang M Vives P
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Purpose of the study: We reviewed 30 cases of osteochondral lesions of the astragalar vault treated surgically.

Material and methods: Among the 30 patients, 17 participated in sports activities and 24 had a history of trauma. Mean delay to surgery was 10 months. Treatment included osteochonritis curettage and Pridie perforations. Direct access was used in 11 cases, malleolar osteotomy in 13 and arthroscopy in 6. Cancellous bone grafts were used in 6 cases.

Results: Mean follow-up was 3 years 7 months (minimum 2 years). All patients had an arthroscan at last follow-up. Evaluation of post-operative outcome was based on clinical assessment and arthroscan findings. Surgical treatment provided very good results in 75 p. 100 of cases with pain relief and improved walking distance.

Discussion: Our cases pointed out the important contribution of the FOG (Fracture Osteonecrosis Geode) classification to pathogenic and prognostic analysis. The Berndt and Harty classifications were not found to be useful.

Conclusion: In case of localized necrosis, we propose arthroscopic perforation curettage. In case of bone loss, a direct cancellous graft may be used.