Prosthetic joint infection (PJI) remains one of the most challenging complications to manage following total joint arthroplasty (TJA). There is a paucity of published data on the management of PJI in smaller, rural hospital settings. In this study, we investigate [1] the success rate of surgical management for PJI following TJA and [2] the microbiology of infecting organisms in this unique geographical environment. We performed a retrospective single-centre study at a rural hospital (Southland Hospital, Invercargill, New Zealand) over a 3-year period (2019 to 2022). All patients presenting with a first episode of PJI fulfilling Musculoskeletal Infection Society criteria after hip or knee arthroplasty were included. All patients had a minimum follow up of 6 months. Treatment success was defined eradication of infection. Twenty-one cases (14 hips and 7 knees) were identified. These were managed with Debridement, antibiotics, and implant retention (DAIR) procedure (n=14, 67%), single-stage revision (n=6, 29%), or long-term suppressive antibiotics (n=1, 4%). Of the DAIR patients, infection recurred in 50% and underwent subsequent revision. Of the single-stage revision patients, 17% failed and underwent subsequent revision. The overall success rate was 90%. Methicillin-sensitive Staphylococcus aureus (MSSA) was the most isolated pathogen (57%,) with no methicillin-resistance Staphylococcus aureus (MRSA) identified. Overall, 90% of infecting organisms were cefazolin sensitive. These results suggest that management of PJI is a safe and viable treatment option when performed in a rural hospital setting, with comparable treatment success rates to urban centres. The incidence of MRSA is low in this setting. Rates of antibiotic resistance were relatively low and most organisms were sensitive to cefazolin, the routine antibiotic used in prophylaxis.
It is unclear if the prevalence of resistance organisms causing (PJI) in total hip/knee arthroplasty is different among North/South American and European countries. Therefore, we sought to compare causative organisms, rates of resistant organisms, and polymicrobial infections in hospitals in North/South America, and Europe. We performed a retrospective study of 654 periprosthetic hip (n=361) and knee (n=293) infections (January 2006-October 2019) identified at two facilities in the United States (US) (n=159), and single institutions located in Argentina (n=99), Uruguay (n=130), United Kingdom (UK) (n=103), Germany (n=59), and Russia (n=104). The analyses were performed for the entire cohort, knees, and hips. Alpha was set at 0.05.Aim
Method
Antibiotic-eluting calcium compounds can be used to deliver antibiotics in the management of prosthetic joint infection (PJI). Described omplications include wound drainage, heterotopic ossification(HO) as well as hypercalcaemia which is potentially life threatening. The aim of this study is to assess the incidence of hypercalcaemia and other complications between two calcium based antibiotic delivery systems. A retrospective study was performed. Thirty two patients treated with Stimulan or Cerament Calcium based antibiotic delivery system between August 2014 to January 2017 were included. Seven patients received Cerament, 21 cases received Stimulan and one patient received both. The volume used as well as pre- and post-operative serum calcium were recorded as well as any wound related complications and radiologic changes suggestive of heterotopic ossification. The postoperative serum adjusted Calcium were taken weekly during the initial post operative period. Patients with overactive parathyroid disease and pre-existing renal disease were excluded.Aim
Method
Revision surgery and debridement and implant retention are recognised approaches for managing prosthetic joint infections (PJI) but may not always be indicated. If the patient is unable to have or declines surgery, prolonged suppressive antibiotic therapy (PSAT) is an option. This study aims to define outcomes of PSAT from a single unit. A retrospective study was performed. All cases of PJI involving the hip or knee between 2012 and 2017 were identified from our institutional database and cross referenced with patient notes. One hundred and seventy eight cases were identified. Of these, 23 (12.9%) (10 hips, 13 knees) were treated with PSAT. Infection was diagnosed based on the MSIS criteria in all cases and all cases were managed by a multidisciplinary team which included specialist microbiologists. One case of long term antifungal therapy was additionally identified. Co-morbidity was assessed using the Charlson co-morbidity index. Exacerbations of infection and need for further surgery were recorded.Aim
Method
The ideal method of fixation for femoral components in total hip arthroplasty (THA) is unknown. While good results have been reported for cemented and uncemented components, there is relatively little published prospective data with twenty years or more of follow up. Results of the Furlong femoral component have been presented at an average of 17 years follow up. We have extended this follow up period to an average of 22.5 years with a minimum of 22 years and a maximum of 25 years. This study included all patients treated using the Furlong femoral component between 1986 and 1991. Patients were reviewed preoperatively and then at 6, 12, 26 and 52 weeks post operatively and annually thereafter. They were assessed clinically and radiographically and the Merle d'Aubigne Postel hip score was calculated at each visit. A Visual Analog Score (VAS) was also recorded to assess patient satisfaction with their procedure. A Kaplan Meier survival analysis was performed.Introduction
Methods
Optimal results from uncemented total hip arthroplasty (THA) requires the prosthesis to obtain initial stability, restoration of biomechanics, bone contact along the ingrowth surface and uniform stress transfer to the proximal femur. Anatomic variation within the population makes this difficult to reproduce in every patient. To achieve optimal fit and fill of the proximal femur, options are reshaping the canal or creating an implant which precisely fits the patient's anatomy. The former increases bone loss and risks weakening the supporting bone, creating areas of stress concentration or shielding. Computer assisted design-computer assisted manufacture (CAD-CAM) femoral components were designed to overcome these issues. We present the long term results of CAD-CAM femoral components used in primary THA. This was a prospective study looking at a consecutive, single surgeon series of THA's. Patients were reviewed pre operatively then at 6 weeks, 3 and 12 months post operatively and then yearly. Clinical as well as radiological review was performed at each visit and Harris Hip Score (HHS), Oxford Hip Score (OHS) and Western Ontario McMaster's (WOMAC) scores were calculated. Kaplan-Meier survival analysis was performed.Introduction
Methods
The variability of the endosteal geometry after removal of the femoral component can make proximal fit difficult to achieve with an ‘off the shelf’ prosthesis. Whatever the anatomy of the proximal femur, it is important to achieve immediate stability, preserve bone stock and protect the femur from cortical defects which can lead to subsequent fracture. In revision Total Hip Arthroplasty (THA) this requires a large inventory of modular components. The use of custom computer-assisted design-computer-assisted manufacture (CAD-CAM) components negates this need. Little has been published on the use of custom-made components in revision THA. We report the results of a cohort of patients who underwent revision THA using CAD-CAM femoral components. A prospective study was performed between 1991 and 1998. A consecutive series of patients who had revision THA using custom components were assessed clinically and radiologically. The design of the femoral components was governed by the existing femoral bone stock. Patients were reviewed pre operatively then at 6 weeks, 3months and 12 months postoperatively and then annually. Radiographs were assessed at each visit and Oxford, Harris and WOMAC hip scores were calculatedIntroduction
Methods
Metal on metal hip resurfacing arthroplasty (MoM HR) has the highest revision rates according to the UK National Joint Registry. Revisions for lesions associated with soft tissue necrosis (pseudotumors) have been associated with poor outcomes. There is a relative paucity of information on early revision of painful HR prostheses. We present the results of a series of patients who underwent early revision of painful MoM HR procedures. This prospective study involved a consecutive series of patients undergoing revision of HR to THA. The diagnoses leading to revision are discussed. Clinical and radiological assessments were performed pre operatively as well as 6 weeks, 12 months postoperatively and yearly thereafter. Pre and post operative Harris Hip Score, Oxford Hip Score and WOMAC scores were calculated. Patient satisfaction was assessed using a visual analogue scale.Introduction
Methods
There is no consensus on the ideal management of young, active patients with disabling coxarthrosis. Within this group, patients with femoral head defects secondary to cysts or avascular necrosis pose particular challenges. Resurfacing arthroplasty is contraindicated and the results of traditional total hip arthroplasty are suboptimal in this group. The BMHR was designed to offer a bone conserving option for these patients. We report the outcome of this device in the short term. This prospective study examines the clinical and radiological outcome of a consecutive series of patients treated with the BMHR arthroplasty. All patients had femoral head defects and disabling hip pain. Patients were reviewed pre operatively and then at 6 weeks, 12 weeks, and 1year post operatively and then yearly. Oxford, Harris and WOMAC hip scores were calculated at each review. Radiological assessment was also performed at each follow up.Introduction
Methods
